A role for myosin II cluster and membrane energy in cortex rupture for Dictyostelium discoideum cells

Emmanuel Asante-Asamani, Daniel Grange, Devarshi Rawal, Zully Santiago, John Loustau & Derrick Brazill
Blebs, pressure driven protrusions of the cell membrane, facilitate the movement of eukaryotic cells such as the soil amoeba Dictyostelium discoideum, white blood cells and cancer cells. Blebs initiate when the cell membrane separates from the underlying cortex. A local rupture of the cortex, has been suggested as a mechanism by which blebs are initiated. However, much clarity is still needed about how cells inherently regulate rupture of the cortex in locations where blebs are...

Registration Year

  • 2022
    1

Resource Types

  • Dataset
    1

Affiliations

  • Hunter College
    1
  • Baruch College
    1
  • Clarkson University
    1
  • Stony Brook University
    1