Additional file 4: Cell type identity scores calculated using SCType for each cell cluster in the full single cell RNAseq atlas.

Additional file 4: Cell type identity scores calculated using SCType for each cell cluster in the full single cell RNAseq atlas.

Additional file 5: Mann-Whitney p-values corresponding to relative frequency differences between RML and mock infected mice for each cell cluster in the full single cell RNAseq atlas.

Additional file 5: Table S2. DEGs in Model, S+Rg, S, and Rg groups.

Additional file 8: Table S5. DEGs uniquely regulated in the S+Rg group.

Persistent Zika virus infection in porcine conceptuses is associated with elevated in utero cortisol levels

En collaboration avec l'Agence de la santé publique du Canada (ASPC), ce tableau fournit aux Canadiens et aux chercheurs des données préliminaires pour surveiller uniquement les cas confirmés de coronavirus (COVID-19) au Canada. Étant donné la nature évolutive rapide de cette situation, ces données sont considérées comme préliminaires. Ce tableau fournira un résumé global des données affichées dans le tableau 13-10-0781-01.

Additional file 2: Table S1. The formula used to calculate R2 and F statistic between exposure and outcome; Table S2. Summary statistics of the anxiety disorders; Table S3–S12. Mendelian Randomization estimation for Amino acid(Table S3); Carbohydrate (Table S4); Co-factor or vitamin(Table S5);Energy(Table S6); Lipid(Table S7); Nucleotide (Table S8); Peptide (Table S9); Xenobiotic(Table S10);X(unknow metabolites) (Table S11);known metabolites (Table S12) on the risk of anxiety disorders; Table S13. The characteristics of SNPs and their genetic associations...

Additional file 6: Mann-Whitney p-values corresponding to relative frequency differences between RML and mock infected mice for each cell sub-cluster in the subset astrocyte dataset.

Additional file 7: Mann-Whitney p-values corresponding to relative frequency differences between RML and mock infected mice for each cell sub-cluster in the subset neuron dataset.

Additional file 9: Mann-Whitney p-values corresponding to relative frequency differences between RML and mock infected mice for each cell sub-cluster in the subset microglia dataset.

Additional file 4: Supplementary Table S1. The clustering results from the tested methods for SARS-CoV-2 sequences found in epidemiologically supported clusters isolated in British Columbia, Canada.

Additional file 13: Supplementary Table 1. The primer sequences in PCR analysis.

Additional file 13: Supplementary Table 1. The primer sequences in PCR analysis.

1. Animal movement influences the spatial spread of directly-transmitted wildlife disease through host-host contact structure. Wildlife disease hosts vary in home range-associated foraging and social behaviors, which may increase the spread and intensity of disease outbreaks. The consequences of variation in host home range movement and space use on wildlife disease dynamics are poorly understood, but could help to predict disease spread and determine more effective disease management strategies. 2. We developed a spatially-explicit individual-based...

In collaboration with the Public Health Agency of Canada (PHAC), this table provides Canadians and researchers with preliminary data to monitor only the confirmed cases of coronavirus (COVID-19) in Canada. Given the rapidly-evolving nature of this situation, these data are considered preliminary. This table will provide an aggregate summary of the data displayed in 13-10-0781-01.

Additional file 1 Supplementary Table S1. The expression levels of 1627 dynamically expressed genes in the reprogramming procedure of rhesus monkey fibroblast cells toward neuroephithelia stem cells. Supplementary Table S2 to S17. The enriched GO terms of genes in Cluster G0 to G15 of Figure 1A, respectively. Supplementary Table S18. The expression levels of 495 dynamically expressed TEs in the reprogramming procedure of rhesus monkey fibroblast cells toward neuroephithelia stem cells. Supplementary Table S19. The...

Additional file 10: Table S7. GO analysis of DEGs uniquely regulated in the S+Rg group.

Additional file 8: Table S5. DEGs uniquely regulated in the S+Rg group.

For nearly 100 years serotyping has been the gold standard for the identification of Salmonella serovars. Despite the increasing adoption of DNA-based subtyping approaches, serotype information remains a cornerstone in food safety and public health activities aimed at reducing the burden of salmonellosis. At the same time, recent advances in whole-genome sequencing (WGS) promise to revolutionize our ability to perform advanced pathogen characterization in support of improved source attribution and outbreak analysis. We present the...

En collaboration avec l'Agence de la santé publique du Canada (ASPC), ce tableau fournit aux Canadiens et aux chercheurs des données préliminaires pour surveiller uniquement les cas confirmés de coronavirus (COVID-19) au Canada. Étant donné la nature évolutive rapide de cette situation, ces données sont considérées comme préliminaires.

Zika virus (ZIKV) infection is a serious public threat with cases reported in about 70 countries and territories. One of the most serious consequences of ZIKV infection is congenital microcephaly in babies. Congenital microcephaly has been suggested to result from infection of neural progenitor cells (NPCs) in the developing fetal brain. However, the molecular and cellular mechanisms underlying microcephaly development remains to be fully elucidated. In this study, we employed quantitative proteomics to determine protein...

The utility of characterizing the effects of strain variation and individual/subgroup susceptibility on dose-response outcomes has motivated the search for new approaches beyond the popular use of the exponential dose-response model for listeriosis. While descriptive models can account for such variation, they have limited power to extrapolate beyond the details of particular outbreaks. In contrast, this study exhibits dose-response relationships from a mechanistic basis, quantifying key biological factors involved in pathogen-host dynamics. An efficient computational...

The PHAC agent-based model was used to explore the progression of the COVID-19 epidemic under three intervention scenarios (infection-preventing vaccination, illness-preventing vaccination and shielding) in individuals above three age thresholds (≥45, ≥55 and ≥65 years) while lifting shutdowns and physical distancing in the community. This data repository contains the PHAC modelling code in Anylogic used for this study.

Additional file 1 Supplementary Table S1. The expression levels of 1627 dynamically expressed genes in the reprogramming procedure of rhesus monkey fibroblast cells toward neuroephithelia stem cells. Supplementary Table S2 to S17. The enriched GO terms of genes in Cluster G0 to G15 of Figure 1A, respectively. Supplementary Table S18. The expression levels of 495 dynamically expressed TEs in the reprogramming procedure of rhesus monkey fibroblast cells toward neuroephithelia stem cells. Supplementary Table S19. The...