Additional file 5: Table S2. DEGs in Model, S+Rg, S, and Rg groups.

Additional file 6: Table S3. Co-regulated DEGs among the three-treatment group and Model group.

Additional file 15: Supplementary Table 3. The results of Univariate Cox regression analysis for pan-cancer.

Additional file 7: Mann-Whitney p-values corresponding to relative frequency differences between RML and mock infected mice for each cell sub-cluster in the subset neuron dataset.

Additional file 8: Differentially expressed transcripts between cells isolated from RML and Mock infected mice within each cell cluster in the full single cell RNAseq atlas. Differentially expressed transcripts were defined by criteria of FDR p-value < 0.05, |log2FC| > 0.5 and �ll-expression difference > -0.1 or < 0.1 for increased/decreased genes respectively.

Growth-regulating factors (GRFs) are plant-specific transcription factors with vital roles in multiple biological processes. Although GRFs have been identified in various plant species, a comprehensive analysis of GRF genes in peach (Prunus persica) has not yet been reported. In this study, 10 PpGRF genes distributed on 6 chromosomes were identified in peach genome and their properties were analyzed systematically. Expression pattern analysis suggested that most PpGRFs were preferentially expressed in young tissues. Multiple types of...

Osimertinib is a recently approved third-generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) that selectively inhibits both EGFR-TKI-sensitizing and EGFR-T790M resistance mutations. The aim of the present meta-analysis was to investigate the efficacy and safety of osimertinib for patients with EGFR-mutated non-small-cell lung cancer (NSCLC). Databases were searched for randomized controlled studies that reported the efficacy and safety of osimertinib versus other treatments (chemotherapy, other EGFR-TKIs, etc.) in treating EGFR-mutated NSCLC. The measured effects...

Additional file 8: Differentially expressed transcripts between cells isolated from RML and Mock infected mice within each cell cluster in the full single cell RNAseq atlas. Differentially expressed transcripts were defined by criteria of FDR p-value < 0.05, |log2FC| > 0.5 and �ll-expression difference > -0.1 or < 0.1 for increased/decreased genes respectively.

Additional file 2: Globally distinguishing transcriptional markers of each cell cluster within the full single-cell atlas. Only positive markers were reported, identified via criteria of |log2FC| > 0.5, FDR p-value < 0.05 and �ll expression difference > 0.1.

Additional file 4: Cell type identity scores calculated using SCType for each cell cluster in the full single cell RNAseq atlas.

Additional file 4: Cell type identity scores calculated using SCType for each cell cluster in the full single cell RNAseq atlas.

Additional file 5: Mann-Whitney p-values corresponding to relative frequency differences between RML and mock infected mice for each cell cluster in the full single cell RNAseq atlas.

Additional file 5: Table S2. DEGs in Model, S+Rg, S, and Rg groups.

Additional file 8: Table S5. DEGs uniquely regulated in the S+Rg group.

Additional file 2: List of differentially expressed gene in RNA-seq.

Additional file 2: List of differentially expressed gene in RNA-seq.

Additional file 9: Table S6. GO analysis of common DEGs in S and S+Rg groups.

Additional file 11: Table S8. KEGG pathway analysis of Model, S+Rg, S, and Rg groups.

Additional file 6: Mann-Whitney p-values corresponding to relative frequency differences between RML and mock infected mice for each cell sub-cluster in the subset astrocyte dataset.

Additional file 14: Supplementary Table 2. The results of expression differences for pan-cancer analysis.

Additional file 14: Supplementary Table 2. The results of expression differences for pan-cancer analysis.

Additional file 5: Mann-Whitney p-values corresponding to relative frequency differences between RML and mock infected mice for each cell cluster in the full single cell RNAseq atlas.

Additional file 6: Table S3. Co-regulated DEGs among the three-treatment group and Model group.

Additional file 7: Table S4. Common DEGs in S and S+Rg groups.

Additional file 7: Table S4. Common DEGs in S and S+Rg groups.