4 Works

Data from: Development and validation of a score to detect paroxysmal atrial fibrillation after stroke

Timo Uphaus, Mark Weber-Krüger, Martin Grond, Gerrit Toenges, Anke Jahn-Eimermacher, Marek Jauss, Paulus Kirchhof, Rolf Wachter & Klaus Gröschel
Objective: Prolonged monitoring times (72h) are recommended to detect paroxysmal atrial fibrillation (pAF) after ischemic stroke, but not yet clinical practice; therefore, an individual patient selection for prolonged ECG monitoring might increase the diagnostic yield of pAF in a resource-saving manner. Methods: We used individual patient data from three prospective studies (ntotal=1556) performing prolonged Holter ECG monitoring (at least 72h) and centralized data evaluation after TIA or stroke in patients with sinus rhythm. Based on...

Qualification and teaching of peer-student tutors in undergraduate medical education: Does it affect the understanding and acquiring of CanMEDS competencies?

Maike Brathuhn, Anja Zimmermann, Cornelia Enzenbach & Daisy Rotzoll
Objective: The Canadian Medical Education Directives for Specialists (CanMEDS), described by scientists of the Royal College of Physicians and Surgeons of Canada, specify the competencies that medical students should acquire during their studies of human medicine. These include the skills of Medical Expert, Communicator, Collaborator, Manager, Professional, Health Advocate and Scholar. We investigated the opinion of former student tutors that are currently active as clinical residents to understand whether they acquired and applied the CanMEDS...

Data from: Comparison of T2*-weighted and QSM contrasts in Parkinson's disease to visualize the STN with MRI

Anneke Alkemade, Gilles De Hollander, Max C. Keuken, Andreas Schäfer, Derek V.M. Ott, David Weise, Sonja A. Kotz, Birte U. Forstmann & Derek V. M. Ott
The subthalamic nucleus (STN) plays a crucial role in the surgical treatment of Parkinson's disease (PD). Studies investigating optimal protocols for STN visualization using state of the art magnetic resonance imaging (MRI) techniques have shown that susceptibility weighted images, which display the magnetic susceptibility distribution, yield better results than T1-weighted, T2-weighted, and T2*-weighted contrasts. However, these findings are based on young healthy individuals, and require validation in elderly individuals and persons suffering from PD. Using...

Genomic basis for skin phenotype and cold adaptation in the extinct Steller's sea cow

Diana Le Duc, Akhil Velluva, Molly Cassatt-Johnstone, Remi-Andre Olsen, Sina Baleka, Chen-Ching Lin, Johannes R. Lemke, John R. Southon, Alexander Burdin, Ming-Shan Wang, Sonja Grunewald, Wilfried Rosendahl, Ulrich Joger, Sereina Rutschmann, Thomas B. Hildebrandt, Guido Fritsch, James A. Estes, Janet Kelso, Love Dalén, Michael Hofreiter, Beth Shapiro & Torsten Schöneberg
Steller’s sea cow, an extinct sirenian and one of the largest Quaternary mammals, was described by Georg Steller in 1741 and eradicated by humans within 27 years. Here, we complement Steller’s descriptions with paleogenomic data from 12 individuals. We identified convergent evolution between Steller’s sea cow and cetaceans but not extant sirenians, suggesting a role of several genes in adaptation to cold environments. Among these are inactivations of lipoxygenase genes, which in humans and mouse...

Registration Year

  • 2021
  • 2018
  • 2017

Resource Types

  • Dataset


  • University Hospital Leipzig
  • University Medical Center of the Johannes Gutenberg University Mainz
  • National Yang Ming Chiao Tung University
  • University Hospitals Birmingham NHS Foundation Trust
  • University of Göttingen
  • Max Planck Institute for Evolutionary Anthropology
  • Curt Engelhorn Centre Archaeometry
  • Institute of Human Genetics
  • Max Planck Institute for Human Cognitive and Brain Sciences
  • Staatliches Naturhistorisches Museum