11 Works

Diagnostic and prognostic role of protein and ultrastructural alterations at cell–extracellular matrix junctions in neoplastic progression of human oral malignancy

Harsh Nitin Dongre, Snehal Mahadik, Chetan Ahire, Pallavi Rane, Shilpi Sharma, Fatima Lukmani, Asawari Patil, Devendra Chaukar, Sudeep Gupta & Sharada Suhas Sawant
Despite advancements in technology and increase in favorable outcomes associated with oral cancer, early detection remains the most significant factor in limiting mortality. The current study aimed to develop early diagnostic and prognostic markers for oral tumorigenesis. Protein and ultrastructural alterations at cell-extracellular matrix (ECM) adhesion junctions were examined concurrently using immunohistochemistry (IHC) and transmission electron microscopy (TEM) on progressive grade of oral carcinomas (n = 285). The expression of hemidesmosome (HD) proteins-integrin β4, BP180,...

Supramolecular Assembly Induced Emission of Thiazole Orange with Sulfobutylether β‐cyclodextrin: A Stimuli‐Responsive Fluorescence Sensor for Tyramine

Raman Khurana, Nilotpal Barooah, Achikanath C. Bhasikuttan & Jyotirmayee Mohanty

Diagnostic and prognostic role of protein and ultrastructural alterations at cell–extracellular matrix junctions in neoplastic progression of human oral malignancy

Harsh Nitin Dongre, Snehal Mahadik, Chetan Ahire, Pallavi Rane, Shilpi Sharma, Fatima Lukmani, Asawari Patil, Devendra Chaukar, Sudeep Gupta & Sharada Suhas Sawant
Despite advancements in technology and increase in favorable outcomes associated with oral cancer, early detection remains the most significant factor in limiting mortality. The current study aimed to develop early diagnostic and prognostic markers for oral tumorigenesis. Protein and ultrastructural alterations at cell-extracellular matrix (ECM) adhesion junctions were examined concurrently using immunohistochemistry (IHC) and transmission electron microscopy (TEM) on progressive grade of oral carcinomas (n = 285). The expression of hemidesmosome (HD) proteins-integrin β4, BP180,...

Ultra‐Bright Rhodamines with Sulfobutylether‐β‐Cyclodextrin: A Viable Supramolecular Dye Laser in Aqueous Medium

Raman Khurana, Sandeep Agarwalla, G. Sridhar, Nilotpal Barooah, Achikanath C. Bhasikuttan & Jyotirmayee Mohanty
Abstract Although aqueous dye lasers are much sought after, they have been of no practical use, as laser dyes show a strong tendency for aggregation in water, thus diminishing their optical output....

Lung cancer with dual EGFR and ALK driver alterations at baseline: a retrospective observational cohort study

Vanita Noronha, Anuradha Chougule, Pratik Chandrani, Rajiv Kumar Kaushal, Vijay Maruti Patil, Nandini Menon, Akhil Kapoor, Sunil Chopade, Ajaykumar Singh, Omshree Shetty, Amit Dutt, Shripad Banavali & Kumar Prabhash
Lung cancer with dual EGFR and ALK driver alterations at baseline: a retrospective observational cohort study

Cyclodextrin-assisted modulation of the photophysical properties and acidity constant of pyrene-armed calix[4]arene

Jyotirmayee Mohanty, V. S. Kalyani & D. D. Malkhede
The supramolecular pKa shift and modulation in the monomer and excimer emission behaviour of pyrene-armed calixarene with cyclodextrins find applications in ratiometric sensing.

The Contrasting Recognition Behavior of β-Cyclodextrin and Its Sulfobutylether Derivative towards 4′,6-Diamidino-2-phenylindole

Jyotirmayee Mohanty, Meenakshi N. Shinde & Achikanath C. Bhasikuttan
Abstract The noncovalent interactions between 4′, 6-diamidino-2-phenylindole (DAPI) and sulfobutylether β-cyclodextrin (SBE7β-CD) are evaluated by using photochemical measurements and compared with...

pH-responsive molecular assemblies of pyridylbutadiene derivative with cucurbit[7]uril

Raman Khurana, Jyotirmayee Mohanty, Anuji K. Vasu & Sriram Kanvah
pH-responsive emission behavior of supramolecular complexes between pyridylbutadiene with CB7 and formation of molecular assemblies is described.

Lung cancer with dual EGFR and ALK driver alterations at baseline: a retrospective observational cohort study

Vanita Noronha, Anuradha Chougule, Pratik Chandrani, Rajiv Kumar Kaushal, Vijay Maruti Patil, Nandini Menon, Akhil Kapoor, Sunil Chopade, Ajaykumar Singh, Omshree Shetty, Amit Dutt, Shripad Banavali & Kumar Prabhash
Lung cancer with dual EGFR and ALK driver alterations at baseline: a retrospective observational cohort study

Redox‐mediated Negative Differential Resistance (NDR) Behavior in Perylenediimide Derivative: A Supramolecular Approach

Jyotirmayee Mohanty, Nilotpal Barooah, Raman Khurana, Narayanan Padma & Achikanath Bhasikuttan
Abstract Deaggregated perylenediimide (PDI) derivatives exhibit exceptionally high quantum yields, photostability and appropriate molecular features for organic electronics. This work demonstrates ...

Modulation in the acidity constant of acridine dye with cucurbiturils: stimuli-responsive pKa tuning and dye relocation into live cells

R. Khurana, N. Barooah, Achikanath Bhasikuttan & Jyotirmayee Mohanty
Cucurbit[7/8]uril–acridine complexes result in striking modulation of the excited state properties of acridine and allowed a tunable upward pKa shift, which is applied for controlled relocation of the dye from the host to live cells.

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  • Homi Bhabha National Institute
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  • Tata Memorial Hospital
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  • Department of Physical and Technical Sciences
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  • Bhabha Atomic Research Centre
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