59 Works

Cooperation-based concept formation in male bottlenose dolphins

Stephanie King, Richard Connor, Michael Krützen & Simon Allen
In Shark Bay, Western Australia, male bottlenose dolphins form a complex nested alliance hierarchy. At the first level, pairs or trios of unrelated males cooperate to herd single females. Multiple first-order alliances cooperate in teams (second-order alliances) in the pursuit and defense of females, and multiple teams also work together (third-order alliances). Yet it remains unknown how dolphins classify these nested alliance relationships. We used 30 years of behavioural data combined with 40 contemporary sound...

Recent activity in expanding populations and purifying selection have shaped transposable element landscapes across natural accessions of the Mediterranean grass Brachypodium distachyon

Christoph Stritt, Sean P Gordon, Thomas Wicker, John P Vogel & Anne C Roulin
Transposable element (TE) activity has emerged as a major cause of variation in genome size and structure among species. To what extent TEs contribute to genetic variation and divergence within species, however, is much less clear, mainly because population genomic data have so far only been available for the classical model organisms. In this study, we use the annual Mediterranean grass Brachypodium distachyon to investigate TE dynamics in natural populations. Using whole-genome sequencing data for...

A liposome assay showing the absence of scrambling in TTYH proteins and a lipidomics analysis of TTYH2

Anastasiia Sukalskaia & Raimund Dutzler
The Tweety homologues (TTYHs) are members of a conserved family of eukaryotic membrane proteins that are abundant in the brain. The three human paralogs were assigned to function as anion channels that are either activated by Ca2+ or cell swelling. To uncover their unknown architecture and its relationship to function, we have determined the structures of human TTYH1–3 by cryo-electron microscopy. All structures display equivalent features of a dimeric membrane protein that contains five transmembrane...

Accompanied versus unaccompanied walking for continuous oxygen saturation measurement during 6-min walk test in COPD: A randomised cross-over study

Thomas F. Riegler, Anja Frei, Sarah R. Haile & Thomas Radtke
Is there is a difference in the 6-Minute Walk Test (6MWT) distance when the assessor accompanies the patient to continuously measure oxygen saturation (SpO2) compared to the patient walking unaccompanied? We conducted a randomised cross-over study to evaluate the impact of the assessor walking with the patient during 6MWT (6MWTwith) versus patient walking alone (6MWTwithout). At the end of a pulmonary rehabilitation programme, each patient performed two 6MWTs in random order and separated by 30...

Ecology drives the evolution of diverse social strategies in Pseudomonas aeruginosa

Alexandre Figueiredo, Andreas Wagner & Rolf Kümmerli
Bacteria often cooperate by secreting molecules that can be shared as public goods between cells. Because the production of public goods is subject to cheating by mutants that exploit the good without contributing to it, there has been great interest in elucidating the evolutionary forces that maintain cooperation. However, little is known on how bacterial cooperation evolves under conditions where cheating is unlikely of importance. Here we use experimental evolution to follow changes in the...

Alternative reproductive tactic in male Drosophila prolongata

Jhoniel Perdigón Ferreira & Stefan Lüpold
Species with intense male-male competition for access to females often show alternative reproductive tactics (ARTs) where males of lower competitive ability adopt a sneaky behavior to gain access to mates. These ARTs are usually associated with intrasexual dimorphisms, in that males with distinct morphologies show different tactics. In some cases, however, males adopt different tactics without being dimorphic. Male Drosophila prolongata exhibit continuous variation in body size and shape, with enlarged forelegs that they use...

Electrophysiological recordings showing allosteric modulation of LRRC8 channels by targeting their cytoplasmic domains with specific sybodies

Sonja Rutz, Dawid Deneka, Raimund Dutzler & Marta Sawicka
Members of the LRRC8 family form heteromeric assemblies, which function as volume-regulated anion channels. These modular proteins consist of a transmembrane pore and cytoplasmic leucine-rich repeat (LRR) domains. Despite their known molecular architecture, the mechanism of activation and the role of the LRR domains in this process has remained elusive. Here we have addressed this question by generating synthetic nanobodies, termed sybodies, which target the LRR domain of the obligatory subunit LRRC8A.We used these binders...

Different molecular changes underlie the same phenotypic transition: Origins and consequences of independent shifts to homostyly within species

Emiliano Mora Carrera
The repeated transition from outcrossing to selfing is a key topic in evolutionary biology. However, the molecular basis of such shifts has been rarely examined due to lack of knowledge of the genes controlling these transitions. A classic example of mating system transition is the repeated shift from heterostyly to homostyly. Occurring in 28 angiosperm families, heterostyly is characterized by the reciprocal position of male and female sexual organs in two (or three) distinct, usually...

African wild dog access to kills

Neil Jordan, Krystyna Golabek, Dominik Behr, Reena Walker, Laura Plimpton, Samantha Lostrom, Megan Claase, Leanne Van Der Weyde & J. Weldon McNutt
Patterns of food sharing in collectively hunting species are likely to influence social dynamics and evolution. Despite this, little is known about competition within social groups at carcasses and other food sources, making the social drivers and implications of food sharing difficult to assess. We quantified carcass access and feeding behavior in free-ranging African wild dogs, Lycaon pictus, at natural kill sites, confirming and quantifying previous descriptions of a youngest-feed-first system. Using data on feeding...

Registration Year

  • 2021

Resource Types

  • Dataset


  • University of Zurich
  • Swiss Federal Institute of Technology in Zurich
  • University of Cambridge
  • Leipzig University
  • Swiss Federal Institute of Aquatic Science and Technology
  • McGill University
  • Swiss Ornithological Institute
  • University of Helsinki
  • Botswana Predator Conservation Trust
  • State University of Campinas