This dataset (Andean_AGB.xlsx) has the data employed in the paper entitled Old-growth Andean forests as globally important carbon sinks and future carbon refuges. The data was compiled as the results of the work of several research teams spread out across the Andean region. The information available here has data about aboveground carbon stocks and dynamics and the main explanatory variables, such as climate and symbiotic root associations.
Data from: Positive allosteric modulation of the α7 nicotinic acetylcholine receptor as a treatment for cognitive deficits after traumatic brain injuryDavid J. Titus, Timothy Johnstone, Nathan H. Johnson, Sidney H. London, Meghana Chapalamadugu, Derk Hogenkamp, Kelvin W. Gee & Coleen M. Atkins
Cognitive impairments are a common consequence of traumatic brain injury (TBI). The hippocampus is a subcortical structure that plays a key role in the formation of declarative memories and is highly vulnerable to TBI. The α7 nicotinic acetylcholine receptor (nAChR) is highly expressed in the hippocampus and reduced expression and function of this receptor are linked with cognitive impairments in Alzheimer’s disease and schizophrenia. Positive allosteric modulation of α7 nAChRs with AVL-3288 enhances receptor currents...
Comparison of adult census size and effective population size support the need for continued protection of two Solomon Island endemicsSarah A. Cowles, Brian C. Weeks, Lindsey Perrin, Nancy Chen & J. Albert C. Uy
Because a population’s ability to respond to rapid change is dictated by standing genetic variation, we can better predict a population’s long-term viability by estimating and then comparing adult census size (N) and effective population size (Ne). However, most studies only measure N or Ne, which can be misleading. Using a combination of field and genomic sequence data, we here estimate and compare N and Ne in two range-restricted endemics of the Solomon Islands. Two...
Interindividual plasticity in metabolic and thermal tolerance traits from populations subjected to recent anthropogenic heatingMelissa Drown, Amanda DeLiberto, Moritz Ehrlich, Douglas Crawford & Marjorie Oleksiak
To better understand temperature’s role in the interaction between local evolutionary adaptation and physiological plasticity, we investigated acclimation effects on metabolic performance and thermal tolerance among natural Fundulus heteroclitus populations from different thermal environments. F. heteroclitus populations experience large daily and seasonal temperature variations, as well as local mean temperature differences across their large geographic cline. In this study, we focus on three populations: one locally heated (32°C) by thermal effluence (TE) from the Oyster...
Construction of a novel risk model based on the random forest algorithm to distinguish pancreatic cancers with different prognoses and immune microenvironment featuresYalan Lei, Rong Tang, Jin Xu, Bo Zhang, Jiang Liu, Chen Liang, Qingcai Meng, Jie Hua, Xianjun Yu, Wei Wang & Si Shi
Immune-related long noncoding RNAs (irlncRNAs) are actively involved in regulating the immune status. This study aimed to establish a risk model of irlncRNAs and further investigate the roles of irlncRNAs in predicting prognosis and the immune landscape in pancreatic cancer. The transcriptome profiles and clinical information of 176 pancreatic cancer patients were retrieved from The Cancer Genome Atlas (TCGA). Immune-related genes (irgenes) downloaded from ImmPort were used to screen 1903 immune-related lncRNAs (irlncRNAs) using Pearson’s...
The dicationic guest 2,7-dimethyldiazapyrenium is bound inside the host cucurbituril, forming a very stable inclusion complex in which the host undergoes structural distortions to accommodate the guest.
Complexation of Ferrocene Derivatives by the Cucurbituril Host: A Comparative Study of the Cucurbituril and Cyclodextrin Host FamiliesAngel E. Kaifer, Vladimir Sindelar, Mikhail V. Rekharsky, Yoshihisa Inoue, Kimoon Kim, Young Ho Ko, N. Selvapalam, Woo Sung Jeon, Kwangyul Moon, Sang Hyun Park, Hyungpil Chun, Jin Yong Lee, Eun Sung Lee, S. Samal & David Sobransingh
The formation of inclusion complexes between cucurbituril (CB) and ferrocene and its derivatives has been investigated. The X-ray crystal structure of the 1:1 inclusion complex between ferrocene and CB revealed that the guest molecule resides in the host cavity with two different orientations. Inclusion of a set of five water-soluble ferrocene derivatives in CB was investigated by 1H NMR spectroscopy and calorimetric and voltammetric techniques. Our data indicate that all neutral and cationic guests form...
Synthesis and Binding Properties of Monohydroxycucurbituril: A Key Derivative for the Functionalization of Cucurbituril HostsNan Dong, Jing He, Tao Li, Andrea Peralta, Mehdi Rashvand Avei, Mingfang Ma & Angel E. Kaifer
We present a simple, direct method to prepare monohydroxylated cucurbituril (CB7-OH) through the direct oxidation of its precursor host, cucurbituril (CB7). Although the conversion takes place in low yield (14%), the isolation of CB7-OH from the reaction mixture is straightforward, and the unreacted CB7 can be easily recovered. ITC measurements with several selected guests confirmed that CB7-OH binds all of them in aqueous solution with similar, albeit slightly lower, binding affinities than those observed with...
First Atlantic satellite tracks of lost years green turtles support the importance of the Sargasso Sea as a sea turtle nurseryKatherine Mansfield, Jeanette Wyneken & Jiangang Luo
In-water behaviour and long-term movements of oceanic-stage juvenile sea turtles are not well described or quantified. This is due to technological or logistical limitations of tracking small, fast-growing animals across long distances and time-periods within marine habitats. Here we present the first long-term offshore tracks of oceanic green turtles (Chelonia mydas) in western North Atlantic waters. Using a tag attachment technique developed specifically for young (<1 year old) green turtles, we satellite tracked 21 oceanic-stage...
2019 Survey of Florida Residents to Evaluate Public Comprehension of the “Cone of Uncertainty” GraphicScotney Evans, Kenneth Broad, Alberto Cairo, Sharanya Majumdar, Brian McNoldy, Barbara Millet & Leigh Rauk
This data set contains results from an online survey targeting a sample of 2,847 Florida residents in 2019. Unlike previous public surveys that focused more on evacuation decisions, forecast usage, and perception of hurricane risk, our approach specifically pays attention to the details of design elements of the forecast graphics with the long-term goal of minimizing misinterpretation of future graphics. The survey comprised 55 mostly multiple-choice and True/False questions, including demographic information and a series...
Regularized satellite tracks from: Ocean warming alters the distributional range, migratory timing, and spatial protections of an apex predator, the tiger shark (Galeocerdo cuvier)Neil Hammerschlag
Data are regularized tiger shark satellite tracks used in "Ocean warming alters the distributional range, migratory timing, and spatial protections of an apex predator, the tiger shark (Galeocerdo cuvier)" published in Global Change Biology. Paper abstract below: Given climate change threats to ecosystems, it is critical to understand responses of species to warming. This is especially important in the case of apex predators since they exhibit relatively high extinction risk and changes to their distribution...
Abstract from the article associated with the dataset: George, Mullinix, et al PeerJ 2021. Reef-building corals are ecosystem engineers that compete with other benthic or- ganisms for space and resources. Corals harvest energy through their surface by photosynthesis and heterotrophic feeding, and they divert part of this energy to defend their outer colony perimeter against competitors. Here, we hypothesized that corals with a larger space-filling surface and smaller perimeters increase energy gain while reducing the...
The carbon isotope fractionation in algal organic matter (Ep), including the long-chain alkenones produced by the coccolithophorid family Noelaerhabdaceae, is used to reconstruct past atmospheric CO2 levels. The conventional proxy linearly relates Ep to changes in cellular carbon demand relative to diffusive CO2 supply, with larger Ep values occurring at lower carbon demand relative to supply (i.e. abundant CO2). However, the response of Gephyrocapsa oceanica, one of the dominant alkenone producers of the last few...
Unusual Electrochemical Properties of the Inclusion Complexes of Ferrocenium and Cobaltocenium with CucurbiturilAngel E. Kaifer & Winston Ong
Ferrocenium and cobaltocenium form highly stable 1:1 inclusion complexes with the host cucurbituril. From electronic absorption spectroscopic data the association equilibrium constants for both complexes were found to be larger than 106 L/mol. The electrochemical reduction of either guest leads to a modest loss in binding affinity.
A supramolecular complex between benzoates and a bambusuril crystallizes out immediately after mixing in chloroform but only in the presence of residual water molecules. In this complex each of the two portals of the macrocycle is occupied by one benzoate. Carboxylate groups are connected through hydrogen bo
Supramolecular Assembly of 2,7-Dimethyldiazapyrenium and Cucurbituril: A New Fluorescent Host for Detection of Catechol and DopamineAngel E. Kaifer, Vladimir Sindelar, Mabel A. Cejas, Françisco M. Raymo, Weizhong Chen & Samantha E. Parker
Abstract The formation of a highly stable inclusion complex between 2,7-dimethyldiazapyrenium (Me2DAP2+) and the cucurbituril host (CB8) was demonstrated by X-ray crystallography; MALDI-TOF mass...
Abstract Methods for the preparation of anion-free bambusuril (BU6) are presented. They are based on the oxidation of iodide anion, which is bound inside the macrocycle, utilizing dark oxidation...
The formation of inclusion complexes between the cucurbituril host and a cationic guest containing ferrocenylmethyl and adamantyl residues connected to an ammonium nitrogen initially leads to an ∼1:1 mixture of two isomeric microscopic complexes, which evolves as a function of time toward the thermodynamically stable mixture, dominated by the adamantyl-included complex.
Pronounced pH effects on the kinetics of cucurbituril-based pseudorotaxane formation and dissociationAngel E. Kaifer, Wei Li, Serena Silvi & Vladimir Sindelar
Deprotonation of the two terminal COOH groups on a 4,4′-bipyridinium linear derivative leads to a pronounced slow down on the kinetics of threading and unthreading by the cucurbituril host.
University of Miami44
University of Tennessee Health Science Center2
North West Agriculture and Forestry University2
Sixth Affiliated Hospital of Sun Yat-sen University2
Sun Yat-sen University2
University of Pennsylvania2
Central South University2
Southwest Medical University2