14 Works

No rebound effect after a course of clopidogrel in patients with acute TIA or minor stroke

Xinmiao Zhang, Jing Jing, Xingquan Zhao, Liping Liu, Anxin Wang, Yuesong Pan, David Wang, S. Claiborne Johnston, Yilong Wang, Yongjun Wang & Xia Meng
Previous studies demonstrated that discontinuation of clopidogrel in patients after ACS was associated with a rebound increase in risk of recurrent events. In this study, we aimed to investigate the rebound effect after discontinuation of clopidogrel therapy in patients with TIA or stroke. All patients with minor stroke or TIA were recruited from the Clopidogrel in High-Risk Patients With Acute Nondisabling Cerebrovascular Events (CHANCE) trial. Patients were divided into two groups: patients who discontinued clopidogrel...

Data from: Local habitat condition rather than geographic distance determines the genetic structure of Tamarix chinensis populations in Yellow River Delta, China

Zhu Zhu, Luoyan Zhang, Lexuan Gao, Shaoqing Tang, Yao Zhao & Ji Yang
Understanding the extent of genetic diversity in natural populations and the correlations between population structure and environmental heterogeneity is of great importance to estimation of the potential for species to undergo rapid adaptive changes in response to environmental variation. In this study, we systematically sampled 800 individuals from 26 Tamarix chinensis populations distributed throughout the Yellow River Delta (YRD) region in China, where a mosaic of habitat patches varying in soil salinity was detected. By...

Additional file 1 of Genetic analysis of 55 cases with fetal skeletal dysplasia

Ying Bai, Yue Sun, Ning Liu, Li Wang, Zhihui Jiao, Yaqin Hou, Huikun Duan, Qianqian Li, Xiaofan Zhu, Jingjing Meng & Xiangdong Kong
Additional file 1. Table S1: 811 genes of a genetic skeletal disease panel; Table S2: Primer sequence in this study; Table S3: Summary of clinical information and molecular results for 55 cases with skeletal abnormalities.

Data from: Petrocodon retroflexus sp. nov. (Gesneriaceae) from a karst cave in Guizhou, China

Jing Guo, Tao Meng, Hongbo Pang & Qiang Zhang
Petrocodon retroflexus Q. Zhang & J. Guo, a new species of Gesneriaceae from Guizhou, China, is described and illustrated. The new species is morphologically similar to Petrocodon viridescens W. H. Chen, Mich. Möller & Y. M. Shui, but differs by its leaf blade being ovate, broadly ovate to elliptic, 8–20 × 5–15 cm and densely pilose on both surfaces, narrowly triangular, 9 mm long, densely pilose bracts, white corolla that is decurved near the middle,...

Data from: Odontochilus napoensis sp. nov. (Orchidoideae: Orchidaceae) from southwestern Guangxi, China

Huan Tang, Hui-Zhe Feng & Yun-Feng Huang
Odontochilus napoensis, a new species from southwestern Guangxi, China, is described and illustrated. It is close to Odontochilus inabae (Hayata) T. P. Lin, but can be distinguished by its glabrous ovary, solitary flower, and 2.0–3.5 mm long filaments of flanges. It is also similar to O. nanlingensis (L. P. Siu & K. Y. Lang) Ormerod, but differs by the solitary, not resupinate flower, and light greenish–brown lateral sepals.

No rebound effect after a course of clopidogrel in patients with acute TIA or minor stroke

Xinmiao Zhang, Jing Jing, Xingquan Zhao, Liping Liu, Anxin Wang, Yuesong Pan, David Wang, S. Claiborne Johnston, Yilong Wang, Yongjun Wang & Xia Meng
Previous studies demonstrated that discontinuation of clopidogrel in patients after ACS was associated with a rebound increase in risk of recurrent events. In this study, we aimed to investigate the rebound effect after discontinuation of clopidogrel therapy in patients with TIA or stroke. All patients with minor stroke or TIA were recruited from the Clopidogrel in High-Risk Patients With Acute Nondisabling Cerebrovascular Events (CHANCE) trial. Patients were divided into two groups: patients who discontinued clopidogrel...

Bitter taste receptor genes of primates

Ping Feng
Bitter taste perception plays a critical role in deterring animals from consuming harmful and toxic substances. To characterize the evolution of primate Tas2rs and test whether dietary preference has shaped the Tas2rs repertoire of primates, we identified Tas2r genes of 35 genomes including 16 Cercopithecidae species, 6 Hominidae species, 4 Cebidae species, 3 Lemuridae species, and other 6 species. The results showed that the total numbers of primates' Tas2rs ranged from 27 to 51, which...

New insights into aging-associated characteristics of female subcutaneous adipose tissue through integrative analysis of multi-omics data

Zichao Li, Shun Wang, Shaojie Liu, Ziwen Xu, Xiaowei Yi, Hongtao Wang, Juanli Dang, Xinxin Wei, Bingyue Feng, Zinuo Liu, Ming Zhao, Qiong Wu & Dahai Hu
Aging could be critical in limiting the application of subcutaneous adipose tissue (SAT) in tissue repair and reconstruction. However, no systematic study on the characteristics of SAT aging has been conducted. In this study, a scanning electronic microscope was used to detect the structural and compositional changes of SAT collected from nine females in three age groups. Multi-omics data of SAT from 37 females were obtained from Gene Expression Omnibus database, and 1860 genes, 56...

New insights into aging-associated characteristics of female subcutaneous adipose tissue through integrative analysis of multi-omics data

Zichao Li, Shun Wang, Shaojie Liu, Ziwen Xu, Xiaowei Yi, Hongtao Wang, Juanli Dang, Xinxin Wei, Bingyue Feng, Zinuo Liu, Ming Zhao, Qiong Wu & Dahai Hu
Aging could be critical in limiting the application of subcutaneous adipose tissue (SAT) in tissue repair and reconstruction. However, no systematic study on the characteristics of SAT aging has been conducted. In this study, a scanning electronic microscope was used to detect the structural and compositional changes of SAT collected from nine females in three age groups. Multi-omics data of SAT from 37 females were obtained from Gene Expression Omnibus database, and 1860 genes, 56...

Sevoflurane reduces lipopolysaccharide-induced apoptosis and pulmonary fibrosis in the RAW264.7 cells and mice models to ameliorate acute lung injury by eliminating oxidative damages

Fushuang Zheng, Xiuying Wu, Jin Zhang, Zhiling Fu & Yan Zhang
Sevoflurane is identified as an effective candidate drug for acute lung injury (ALI) treatment, but its curing effects and detailed mechanisms have not been fully disclosed. The present study was designed to resolve this academic issue. The ALI mice models were established, and Hematoxylin-eosin staining assay was performed to examine tissue morphologies. Cell viability was determined by CCK-8 assay, and Annexin V-FITC/PI double staining assay was used to examine cell apoptosis. The expression levels of...

Data from: Cytology and sexuality of 11 species of Elatostema (Urticaceae) in limestone karsts suggests that apomixis is a recurring phenomenon

Long-Fei Fu, Lan-Ying Su, Azim Mallik, Fang Wen & Yi-Gang Wei
Limestone karsts across southern China to southeastern Asia are renowned biodiversity hotspots. The karst are characterized by exposed calcareous rocks, seasonal droughts and thin soils that are deficient in N and P but with high Ca and Mg content. The stressful habitat may result in high biodiversity through mechanisms such as niche differentiation, hybridization, polyploidy and apomixis. The genus Elatostema (Urticaceae) has particularily high species diversity in this area and can be used a model...

Shared response to changes in drainage basin: Phylogeography of the Yunnan Small Narrow-mouthed Frog, Glyphoglossus yunnanensis (Anura: Microhylidae)

Dong Ru Zhang, Hong Hui, Guo Hua Yu, Shuo Liu, Si Qi Yuan, Heng Xiao, Ding Qi Rao & Xin Qiang Song
Aim: With the late Cenozoic uplift of the Qinghai-Tibetan Plateau (QTP), drainage of the southeastern edge of the QTP changed significantly. However, the impact of this dramatic change on the geographical distribution and genetic diversity of endemic organisms is still poorly understood. Here, we examined the geographical patterns of genetic variation in the Yunnan small narrow-mouthed frog, Glyphoglossus yunnanensis (Microhylidae), and two alternative hypotheses were tested: that is, the geographical distribution of genetic variation was...

Sevoflurane reduces lipopolysaccharide-induced apoptosis and pulmonary fibrosis in the RAW264.7 cells and mice models to ameliorate acute lung injury by eliminating oxidative damages

Fushuang Zheng, Xiuying Wu, Jin Zhang, Zhiling Fu & Yan Zhang
Sevoflurane is identified as an effective candidate drug for acute lung injury (ALI) treatment, but its curing effects and detailed mechanisms have not been fully disclosed. The present study was designed to resolve this academic issue. The ALI mice models were established, and Hematoxylin-eosin staining assay was performed to examine tissue morphologies. Cell viability was determined by CCK-8 assay, and Annexin V-FITC/PI double staining assay was used to examine cell apoptosis. The expression levels of...

Additional file 1 of Genetic analysis of 55 cases with fetal skeletal dysplasia

Ying Bai, Yue Sun, Ning Liu, Li Wang, Zhihui Jiao, Yaqin Hou, Huikun Duan, Qianqian Li, Xiaofan Zhu, Jingjing Meng & Xiangdong Kong
Additional file 1. Table S1: 811 genes of a genetic skeletal disease panel; Table S2: Primer sequence in this study; Table S3: Summary of clinical information and molecular results for 55 cases with skeletal abnormalities.

Registration Year

  • 2022
    10
  • 2017
    1
  • 2016
    2
  • 2015
    1

Resource Types

  • Dataset
    14

Affiliations

  • Guangxi Normal University
    14
  • Chinese Academy of Sciences
    7
  • Zhejiang University
    6
  • Jilin University
    6
  • Fudan University
    6
  • Huazhong University of Science and Technology
    5
  • Jiangsu Academy of Agricultural Sciences
    4
  • Henan University
    4
  • Southwest Medical University
    4
  • Air Force Medical University
    4