It is of the utmost importance for the elements that influence public compliance to the COVID-19 vaccine to be assessed, including misconceptions, rumors, and conspiracy theories. Hence our study aimed to estimate the distribution of the most common misconceptions and their predictors in Saudi Arabia. We distributed an online questionnaire to participants who were 18 years or older at the time of the survey, which included four sections: demographic characteristics of participants, level of their...

Abstract There is a global improvement in critical care services that leads to prolonged survival after ICU stay. This improvement has increased the demand for multidisciplinary critical care services beyond the ICU. Recently, efforts focused on the patient’s quality of life after ICU discharge and family involvement in their care. Most older adults who survive an ICU stay are challenged by complex medication changes following discharge, as are their caregivers. Limited literature addresses the standard...

Additional file 3: Table S2. The up- and down-regulated N-glycopeptides.

Additional file 2: Table S2. Association results for the multi-ancestry index SNPs with the gene prioritization.

Additional file 17: Table S9. PheWAS UKB-MVP meta-analysis results for each index lipid variant at Bonferroni threshold for multiple testing p<=3.5e-8)

Additional file 10: Table S7. DESE phenotype-tissue association results using both GTEx gene-level and transcript-level selective expression.

Additional file 22: Table S14. Test for difference in effects for index variants from sex-stratified meta-analysis.

Additional file 23: Table S15. Comparison of the sex-specific effects.

Additional file 23: Table S15. Comparison of the sex-specific effects.

Additional file 25: Table S16. Comparison of effect size estimates for sex-stratified analysis in the replication cohorts.

Acne Vulgaris is one of the most common chronic inflammatory skin disorders that affect majority of teen-agers worldwide. Isotretinoin (ITT) is the drug of choice in the management of acne, but, it suffers from serious side-effects including hepatotoxicity, and some psychological disturbances following its oral intake. The objective of this study was to develop and optimize ITT loaded nanoemulsions (ITT-SNEDDS) and to incorporate resveratrol (RSV)in optimum formulation to decrease ITT side effects The ITT solubility...

Nanosized copper silicates with three different structural morphology (amorphous, nanotubes and MEL) were prepared using different synthesis methods. The physico-chemical properties of copper silicates were characterized by XRD, FT-IR, SEM, HRTEM, N2-physisorption, XPS and H2-TPR techniques. The results indicated that the preparation conditions affect reduction behavior and textural properties of nanosized copper silicates. Hydrothermal synthesis method yielded chrysocolla-like CuSiO3 nanotubes, which possessed high surface area and pore volume with easy reducibility. The catalytic performances of...

Additional file 19: Table S11. Significant female-specific multi-ancestry meta-analysis results.

Additional file 19: Table S11. Significant female-specific multi-ancestry meta-analysis results.

Additional file 29: Table S19. Comparison of sex-stratified effect sizes in the UK Biobank for BMI, waist hip ratio adjusted for BMI, alcohol use, and smoking status.

Additional file 8: Table S6. Association of lipid index variants with CAD, T2D and NAFLD.

Additional file 1: Table S1. Characteristics of contributing cohorts (as provided by each participating cohort).

Additional file 2: Table S1. Differentially expressed genes related with ERQC and ERAD.

To date, publicly available plastid genomes of legumes have for the most part been limited to the subfamily Papilionoideae. Here we report 13 new plastid genomes of legumes spanning all three subfamilies. The genomes representing Caesalpinioideae and Mimosoideae are highly conserved in gene content and gene order, similar to the ancestral angiosperm genome organization. Genomes within the Papilionoideae, however, have reduced sizes due to deletions in nine intergenic spacers primarily in the large single copy...

Additional file 5: Table S4. Frequency of lipid-related publications for the PoPS+ prioritized genes.

A parenteral medical combination containing vaborbactam (VBR) and meropenem (MRP) is used mainly to treat complicated urinary tract infections. A novel ultra-performance liquid chromatography (UPLC)- tandem mass spectrometric (MS/MS) method was developed for the sensitive determination of both compounds in human plasma. Sample preparation was performed by precipitation technique. The chromatographic separation was accomplished using the Acquity C18-BEH column, 0.01 M ammonium formate: acetonitrile (47:53, v/v) as a mobile phase with a flow rate of...

The gut microbiota is often affected by the dietary and lifestyle habits of the host, resulting in a better efficacy that favors energy harvesting from the consumed food. Our objective was to characterize the composition of gut microbiota in adult Saudis and investigate possible association with lifestyle and dietary practices. Feces from 104 Saudi volunteers (48% males) were tested for microbiota by sequencing the V3-V4 region of bacterial 16S ribosomal RNA (rRNA). For all participants,...

Additional file 12: Table S8. PheWAS UKB-MVP meta-analysis results for each lipid PGS.

Additional file 30: Table S20. Colocalization results for the sex-specific loci.

Additional file 33: Table S22. Mouse genes with lipid phenotypes (silver set).