4 Works

What does it mean to be wild? Assessing anthropogenic environments of nonhuman primate specimens in museum collections

Andrea Eller, Stephanie Canington, Sana Saiyed, Courtney Hoffman, Rita Austin & Sabrina Sholts
Natural history collections are often thought to represent environments in a pristine natural state, free from human intervention – the so-called “wild”. In this study, we aim to assess the level of human influence represented by natural history collections of wild-collected primates over 120 years at the Smithsonian Institution’s National Museum of Natural History (NMNH). Our sample consisted of 875 catarrhine primate specimens in NMNH collections, representing 13 genera collected from 39 countries (1882–2004). Using...

High-density 3-D coordinate data of avian and non-avian dinosaur endocasts

Akinobu Watanabe, Amy Balanoff, Paul Gignac, M. Eugenia Gold & Mark Norell
How do large and unique brains evolve? Historically, comparative neuroanatomical studies have attributed the evolutionary genesis of highly encephalized brains to deviations along, as well as from, conserved scaling relationships among brain regions. However, the relative contributions of these concerted (integrated) and mosaic (modular) processes as drivers of brain evolution remain unclear, especially in non-mammalian groups. While proportional brain sizes have been the predominant metric used to characterize brain morphology to date, we perform a...

Draft de novo genome assembly of the elusive jaguarundi, Puma yagouaroundi

Gaik Tamazian, Pavel Dobrynin, Anna Zhuk, Daria Zhernakova, Polina Perelman, Natalia Serdyukova, Alexander Graphodatsky, Aleksey Komissarov, Sergei Kliver, Nikolay Cherkasov, Alan Scott, David Mohr, Klaus-Peter Koepfli, Stephen O'Brien & Ksenia Krasheninnikova
The Puma lineage within the family Felidae consists of three species that last shared a common ancestor around 4.9 million years ago. Whole-genome sequences of two species from the lineage were previously reported: the cheetah (Acinonyx jubatus) and the mountain lion (Puma concolor). The present report describes a whole-genome assembly of the remaining species, the jaguarundi (Puma yagouaroundi). We sequenced the genome of a male jaguarundi with 10X Genomics linked reads and assembled the whole-genome...

Large mitochondrial DNA deletions in HIV sensory neuropathy

Ricardo Roda, David Bargiela, Weiran Chen, Ken Perry, Ronald J. Ellis, David B. Clifford, Ajay Bharti, Asha Kallianpur, Michelli F Oliveira, Monica M. Diaz, Leah H. Rubin, Christina Gavegnano, Justin C. McArthur, Ahmet Hoke & Michael Polydefkis
Objective: The primary objective of this study was to evaluate the correlation of large mitochondrial DNA deletions in skin samples of people with HIV with measure of neuropathy and prior exposure to therapy. We hypothesized that deletions would be associated with the presence of neuropathy. As secondary objectives we determined the correlation of deletion burden with demographic data and neuropathy measures. Methods: In this retrospective cohort study we measured the accumulation of large mtDNA deletions...

Registration Year

  • 2021

Resource Types

  • Dataset


  • Johns Hopkins University School of Medicine
  • Emory University School of Medicine
  • University of Notre Dame
  • University of California, San Diego
  • New York Institute of Technology
  • Smithsonian Institution
  • University of Oslo
  • Washington University in St. Louis
  • Saint Petersburg State University
  • University of Oklahoma