9 Works

Data from: MHC structuring and divergent allele advantage in a urodele amphibian: a hierarchical multi-scale approach

Lorenzo Talarico, Wieslaw Babik, Silvio Marta, Venusta Pietrocini & Marco Mattoccia
The proteins encoded by extraordinarily polymorphic major histocompatibility complex (MHC) genes are involved in the adaptive immune response. Balancing selection is believed to maintain MHC polymorphism in the long-term, although neutral processes also play a role in shaping MHC diversity. However, the relative contribution of these processes is poorly understood. Here we characterized MHC class II variation of a low-dispersal, pond-breeding newt (Triturus carnifex) over a restricted, geographically structured area. We aimed to: (1) evaluate...

Archived data for: Balancing selection, genetic drift, and human mediated-introgression interplay to shape MHC (functional) diversity in Mediterranean brown trout

Lorenzo Talarico, Silvio Marta, Anna Rita Rossi, Simone Crescenzo, Gerardo Petrosino, Marco Martinoli & Lorenzo Tancioni
The extraordinary polymorphism of Major Histocompatibility Complex (MHC) genes is considered a paradigm of pathogen-mediated balancing selection, although empirical evidence is still scarce. Furthermore, the relative contribution of balancing selection to shape MHC population structure and diversity, compared to that of neutral forces, as well as its interaction with other evolutionary processes such as hybridization, remains largely unclear. To investigate these issues, we analysed adaptive (MHC-DAB gene) and neutral (11 microsatellite loci) variation in 156...

Lattice Boltzmann simulations on the tumbling to tank-treading transition: effects of membrane viscosity

Fabio Guglietta, Marek Behr, Luca Biferale, Giacomo Falcucci & Mauro Sbragaglia
The tumbling to tank-treading (TB-TT) transition for red blood cells (RBCs) has been widely investigated, with a main focus on the effects of the viscosity ratio λ (i.e., the ratio between the viscosities of the fluids inside and outside the membrane) and the shear rate γ ̇ applied to the RBC. However, the membrane viscosity μm plays a major role in a realistic description of RBC’s dynamics, and only a few works have systematically focused...

Data from: All is fish that comes to the net: metabarcoding for rapid fisheries catch assessment

Lorenzo Talarico, Tommaso Russo, Giulia Maiello, Charles Baillie, Giuliano Colosimo, Lorenzo D'Andrea, Federico Di Maio, Fabio Fiorentino, Simone Franceschini, Germana Garofalo, Dario Scannella, Stefano Cataudella & Stefano Mariani
AbstractMonitoring marine resource exploitation is a key activity in fisheries science and biodiversity conservation. Since research surveys are time-consuming and costly, fishery-dependent data (i.e. derived directly from fishing vessels) are increasingly credited with a key role in expanding the reach of ocean monitoring. Fishing vessels may be seen as widely ranging data-collecting platforms, which could act as a fleet of sentinels for monitoring marine life, in particular exploited stocks. Here, we investigate the possibility of...

Data from: The speed–curvature power law in Drosophila larval locomotion

Myrka Zago, Francesco Lacquaniti & Alex Gomez-Marin
We report the discovery that the locomotor trajectories of Drosophila larvae follow the power-law relationship between speed and curvature previously found in the movements of human and non-human primates. Using high-resolution behavioural tracking in controlled but naturalistic sensory environments, we tested the law in maggots tracing different trajectory types, from reaching-like movements to scribbles. For most but not all flies, we found that the law holds robustly, with an exponent close to three-quarters rather than...

Data from: Hybridization masks speciation in the evolutionary history of the Galápagos marine iguana

Amy MacLeod, Ariel Rodríguez, Miguel Vences, Pablo Orozco-TerWengel, Carolina García, Fritz Trillmich, Gabriele Gentile, Adalgisa Caccone, Galo Quezada & Sebastian Steinfartz
The effects of the direct interaction between hybridization and speciation—two major contrasting evolutionary processes—are poorly understood. We present here the evolutionary history of the Galápagos marine iguana (Amblyrhynchus cristatus) and reveal a case of incipient within-island speciation, which is paralleled by between-island hybridization. In-depth genome-wide analyses suggest that Amblyrhynchus diverged from its sister group, the Galápagos land iguanas, around 4.5 million years ago (Ma), but divergence among extant populations is exceedingly young (less than 50...

Microsatellite data from: Genetic assessment reveals inbreeding, possible hybridization and low levels of genetic structure in a declining goose population

Johanna Honka, Serena Baini, Jeremy Searle, Laura Kvist & Jouni Aspi
The population numbers of taiga bean goose (Anser fabalis fabalis) have halved during recent decades. Since this subspecies is hunted throughout most of its range, the decline is of management concern. Knowledge of the genetic population structure and diversity is important for guiding management and conservation efforts. Genetically unique subpopulations might be hunted to extinction if not managed separately, and any inbreeding depression or lack of genetic diversity may affect the ability to adapt to...

Data from: Magnetic resonance and ultrasound contrast imaging of polymer-shelled microbubbles loaded with iron oxide nanoparticles

Claudia Sciallero, Luca Balbi, Gaio Paradossi & Andrea Trucco
Dual-mode contrast agents (CAs) have great potential for improving diagnostics. However, the effectiveness of CAs is strictly related to both the solution adopted to merge the two agents into a single probe unit, and the ratio between the two agents. In this study, two dual-mode CAs for simultaneous magnetic resonance imaging (MRI) and ultrasound imaging (UI) were assessed. For this purpose, different densities of superparamagnetic iron oxide nanoparticles (SPIONs) were anchored to the external surface...

Velocity, density and energy budget statistics from the article: Validation and application of the lattice Boltzmann algorithm for a turbulent immiscible Rayleigh-Taylor system

Hugo Saraiva Tavares, Luca Biferale, Mauro Sbragaglia & Alexei Abaevich Mailybaev
We develop a multicomponent lattice Boltzmann (LB) model for the 2D Rayleigh--Taylor turbulence with a Shan-Chen pseudopotential implemented on GPUs. Accuracy of the LB model is tested both for early and late stages of instability. For the developed turbulent motion we analyze the balance between different terms describing variations of the kinetic and potential energies. Then, we analyze the role of interface in the energy balance, and also the effects of the vorticity induced by...

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  • University of Rome Tor Vergata
  • University of Milan
  • University of Genoa
  • Technische Universität Braunschweig
  • University of Bologna
  • Miguel Hernandez University
  • Charles Darwin Foundation
  • University of Salford
  • Instituto Nacional de Matemática Pura e Aplicada
  • Sapienza University of Rome