2 Works

Data from: Genome-wide patterns of transposon proliferation in an evolutionary young hybrid fish

Stefan Dennenmoser, Fritz J. Sedlazeck, Michael C. Schatz, Janine Altmüller, Matthias Zytnicki & Arne W. Nolte
Hybridization can induce transposons to jump into new genomic positions, which may result in their accumulation across the genome. Alternatively, transposon copy numbers may increase through non-allelic (ectopic) homologous recombination in highly repetitive regions of the genome. The relative contribution of transposition bursts versus recombination-based mechanisms to evolutionary processes remains unclear because studies on transposon dynamics in natural systems are rare. We assessed the genome-wide distribution of transposon insertions in a young hybrid lineage (“invasive...

Data from: Long-term evolution on complex fitness landscapes when mutation is weak

David M. McCandlish
Understanding evolution on complex fitness landscapes is difficult both because of the large dimensionality of sequence space and the stochasticity inherent to population-genetic processes. Here I present an integrated suite of mathematical tools for understanding evolution on time-invariant fitness landscapes when mutations occur sufficiently rarely that the population is typically monomorphic and evolution can be modeled as a sequence of well-separated fixation events. The basic intuition behind this suite of tools is that surrounding any...

Registration Year

  • 2018

Resource Types

  • Dataset


  • Cold Spring Harbor Laboratory
  • University of Cologne
  • Johns Hopkins University
  • French National Institute for Agricultural Research
  • Carl von Ossietzky University of Oldenburg