937 Works

From crypsis to masquerade: ontogeny changes the colour defences of a crab spider hiding as bird droppings

Long Yu, Xin Xu, Fan Li, Wei Zhou, Hua Zeng, Eunice Tan, Shichang Zhang & Daiqin Li
Selection imposed by visually-hunting predators has driven the evolution of colour-based antipredator defence strategies such as crypsis, masquerade, mimicry and aposematism. Individuals of many animals are generally considered to rely on a single type of defence strategy, but individuals of some species use multiple colour-based defences. Many animals switch between colour-based defences against visually-hunting predators during ontogeny. However, why this occurs remains poorly understood. The crab spider Phrynarachne ceylonica is an often-cited example of a...

Rivers as the largest source of mercury to coastal oceans worldwide

Maodian Liu, Qianru Zhang, Taylor Maavara, Shaoda Liu, Xuejun Wang & Peter Raymond
Mercury is a potent neurotoxic substance and accounts for 250,000 intellectual disabilities annually. Worldwide, coastal fisheries contribute the majority of human exposure to mercury through fish consumption. Recent global mercury cycling and risk models attribute all the mercury loading to the ocean to atmospheric deposition. Nevertheless, new regional research has noted that the riverine mercury export to coastal oceans may also be significant to the oceanic burden of mercury. Here we construct an unprecedented high-spatial-resolution...

Protein disulfide isomerases (PDIs) negatively regulate ebolavirus structural glycoprotein expression in the endoplasmic reticulum (ER) via the autophagy-lysosomal pathway

Bin Wang, Jing Zhang, Xin Liu, Qingqing Chai, Xiaoran Lu, Xiaoyu Yao, Zhichang Yang, Liangliang Sun, Silas F. Johnson, Richard C Schwartz & Yong-Hui Zheng
Zaire ebolavirus (EBOV) causes a severe hemorrhagic fever in humans and non-human primates with high morbidity and mortality. EBOV infection is dependent on its structural glycoprotein (GP), but high levels of GP expression also trigger cell rounding, detachment, and downregulation of many surface molecules that is thought to contribute to its high pathogenicity. Thus, EBOV has evolved an RNA editing mechanism to reduce its GP expression and increase its fitness. We now report that the...

Rapid increase in China’s industrial ammonia emissions: evidence from unit-based mapping

Yuang Chen, Qianru Zhang, Xingrui Cai, Haoran Zhang, Huiming Lin, Chaoyue Zheng, Zhanqiang Guo, Shanying Hu, Long Chen, Shu Tao, Maodian Liu & Xuejun Wang
Ammonia (NH3) is an important precursor of secondary inorganic aerosols and greatly impacts nitrogen deposition and acid rain. Previous studies have mainly focused on the agricultural NH3 emissions, while recent research has noted that industrial sources could be significant in China. However, detailed estimates of NH3 emitted from industrial sectors in China are lacking. Here we established an unprecedented high-spatial-resolution dataset of China’s industrial NH3 emissions using up-to-date measurements of NH3 and point source-level information...

High dimensionality of stoichiometric niches in soil fauna

Bing Zhang, Haozhen Chen, Mingqin Deng, Jingyi Li, Angélica González & Shaopeng Wang
The ecological niche is a fundamental concept to understand species coexistence in natural communities. The recently developed framework of the multidimensional stoichiometric niche (MSN) characterizes species niches using chemical elements in living organisms. Despite the fact that living organisms are composed by multiple elements, stoichiometric studies have so far mostly focused on carbon (C), nitrogen (N), and phosphorus (P), and therefore a quantitative analysis of the dimensionality of the MSN in living organisms is still...

Turbulent Mechanisms for the Deep Convective Boundary Layer in the Taklimakan Desert

Hongsheng Zhang, Lu Zhang, Wei Wei & Ali Mamtimin
The deep convective boundary layer (CBL) in the Taklimakan Desert plays an important role in the climate system in East Asia. Based on the observation experiment and large-eddy simulation, turbulent mechanisms for its formation were revealed in this study. This explained why the daily maximum CBL depth was independent of surface heating. In the late-morning, there was a weak temperature inversion and a near-neutral residual layer (RL) above the CBL. With the development of the...

Optimization of the vancomycin administration regimen by clinical pharmacists based on a population pharmacokinetics model: a prospective interventional study

Haodi Lu, Lufen Duan, Yanxia Yu, Jingjing Li, Lu Shi, Sudong Xue, Qian Zhang, Qin Zhou, Chenqi Zhu, Erning Shang, Xinxin Yan & Lian Tang
In vancomycin treatment, the rates of correct blood sampling and initial trough concentrations within the target range are very low. Studies of interventions by clinical pharmacists based on population pharmacokinetics (PPK) models are limited. This study aimed to evaluate the intervention effect of clinical pharmacist-mediated optimization of the vancomycin administration regimen based on a PPK model. Retrospectively enrolled patients constituted the control group, and prospectively enrolled patients constituted the intervention group. The vancomycin administration regimen,...

Additional file 2 of Dissecting super-enhancer driven transcriptional dependencies reveals novel therapeutic strategies and targets for group 3 subtype medulloblastoma

Meng Li, Yujie Han, Chaochen Wang, Wenfeng Kang, Wenyan Jiang, Lei Zhang & Yujie Tang
Additional file 2: Supplementary Table S2

Additional file 5 of Dissecting super-enhancer driven transcriptional dependencies reveals novel therapeutic strategies and targets for group 3 subtype medulloblastoma

Meng Li, Yujie Han, Chaochen Wang, Wenfeng Kang, Wenyan Jiang, Lei Zhang & Yujie Tang
Additional file 5: Supplementary Table S5

Additional file 4 of Dissecting super-enhancer driven transcriptional dependencies reveals novel therapeutic strategies and targets for group 3 subtype medulloblastoma

Meng Li, Yujie Han, Chaochen Wang, Wenfeng Kang, Wenyan Jiang, Lei Zhang & Yujie Tang
Additional file 4: Supplementary Table S4

Data from: Nitrogen enrichment alters multiple dimensions of grassland functional stability via changing compositional stability

Qianna Xu, Xian Yang, Jian Song, Jingyi Ru, Jianyang Xia, Shaopeng Wang, Shiqiang Wan & Lin Jiang
Anthropogenic nutrient enrichment is known to alter the composition and functioning of plant communities. However, how nutrient enrichment influences multiple dimensions of community- and ecosystem-level stability remains poorly understood. Using data from a nitrogen (N) and phosphorus (P) addition experiment in a temperate semi-arid grassland that experienced a natural drought, we show that N enrichment, not P enrichment, decreased grassland functional and compositional temporal stability, resistance, and recovery, but increased functional and compositional resilience. Compositional...

Additional file 3 of Rapid and sensitive single-cell RNA sequencing with SHERRY2

Lin Di, Bo Liu, Yuzhu Lyu, Shihui Zhao, Yuhong Pang, Chen Zhang, Jianbin Wang, Hai Qi, Jie Shen & Yanyi Huang
Additional file 3: Table S2.Comparison of SHERRY and SHERRY2 performances on bulk RNA. (recording data values of Additional file 1: Fig. S2).

Additional file 3 of Rapid and sensitive single-cell RNA sequencing with SHERRY2

Lin Di, Bo Liu, Yuzhu Lyu, Shihui Zhao, Yuhong Pang, Chen Zhang, Jianbin Wang, Hai Qi, Jie Shen & Yanyi Huang
Additional file 3: Table S2.Comparison of SHERRY and SHERRY2 performances on bulk RNA. (recording data values of Additional file 1: Fig. S2).

Additional file 4 of Mutagenesis of the odorant receptor co-receptor (Orco) reveals severe olfactory defects in the crop pest moth Helicoverpa armigera

Xiao-Bin Fan, Bao-Tong Mo, Guo-Cheng Li, Ling-Qiao Huang, Hao Guo, Xin-Lin Gong & Chen-Zhu Wang
Additional file 4. Table S2. Summary of the chemicals used in our experiments.

Additional file 10 of Small molecule modulation of microbiota: a systems pharmacology perspective

Qiao Liu, Bohyun Lee & Lei Xie
Additional file 10. Table S9. Background targets list used in target functional annotation analysis.

Additional file 2 of Small molecule modulation of microbiota: a systems pharmacology perspective

Qiao Liu, Bohyun Lee & Lei Xie
Additional file 2. Table S1. Microbes with pathogenic effects on human health by manually literature review.

Additional file 4 of Small molecule modulation of microbiota: a systems pharmacology perspective

Qiao Liu, Bohyun Lee & Lei Xie
Additional file 4. Table S3. The Microbes with unknown effects in literature reviews and their SRWR inferred microbe effects.

Additional file 6 of Small molecule modulation of microbiota: a systems pharmacology perspective

Qiao Liu, Bohyun Lee & Lei Xie
Additional file 6. Table S5. Drugs that are found in both drug screen results using Drugbank database and that using STITCH database.

Additional file 7 of Small molecule modulation of microbiota: a systems pharmacology perspective

Qiao Liu, Bohyun Lee & Lei Xie
Additional file 7. Table S6. Potential homolog proteins that have homologs with pathogenic microbe proteins but do not have homologs with commensal microbe proteins.

Additional file 2 of Mutagenesis of the odorant receptor co-receptor (Orco) reveals severe olfactory defects in the crop pest moth Helicoverpa armigera

Xiao-Bin Fan, Bao-Tong Mo, Guo-Cheng Li, Ling-Qiao Huang, Hao Guo, Xin-Lin Gong & Chen-Zhu Wang
Additional file 2. Table S1. The TPM value of main olfactory related genes in Orco-/- and wild type.

Additional file 2 of Comprehensive analysis of alternative polyadenylation regulators concerning CD276 and immune infiltration in bladder cancer

Ming Xiong, Wencheng Li, Longwang Wang, Liang Chen, Zhaohui Chen, Chengcheng Wei, Futian Zhang, Jiawei Chen, Gallina Kazobinka, Jun Zhao & Teng Hou
Additional file 2: Supplementary Table 1. The results of the GSEA.

Additional file 2 of Comprehensive analysis of alternative polyadenylation regulators concerning CD276 and immune infiltration in bladder cancer

Ming Xiong, Wencheng Li, Longwang Wang, Liang Chen, Zhaohui Chen, Chengcheng Wei, Futian Zhang, Jiawei Chen, Gallina Kazobinka, Jun Zhao & Teng Hou
Additional file 2: Supplementary Table 1. The results of the GSEA.

Additional file 1 of Circulating tumor DNA integrating tissue clonality detects minimal residual disease in resectable non-small-cell lung cancer

Siwei Wang, Ming Li, Jingyuan Zhang, Peng Xing, Min Wu, Fancheng Meng, Feng Jiang, Jie Wang, Hua Bao, Jianfeng Huang, Binhui Ren, Mingfeng Yu, Ninglei Qiu, Houhuai Li, Fangliang Yuan, Zhi Zhang, Hui Jia, Xinxin Lu, Shuai Zhang, Xiaojun Wang, Youtao Xu, Wenjia Xia, Tongyan Liu, Weizhang Xu, Xinyu Xu … & Rong Yin
Additional file 1. Table S1: Patient demography.

Additional file 10 of Transcriptomic analysis of paternal behaviors in prairie voles

Florian Duclot, Yan Liu, Samantha K. Saland, Zuoxin Wang & Mohamed Kabbaj
Additional file 10. Differential expression analysis details. For conciseness, the labels of pairwise comparisons were coded in two letters: the first one represents the phenotype (M: mothers, F: fathers, P: paternal males, A: attackers), whereas the second one represents the structure (M: MPOA, N: NAc, L: LS). For instance, PLvAL refers to the comparison between the Paternal and Attackers phenotypes in the LS. DE: differentially expressed.

Additional file 10 of Transcriptomic analysis of paternal behaviors in prairie voles

Florian Duclot, Yan Liu, Samantha K. Saland, Zuoxin Wang & Mohamed Kabbaj
Additional file 10. Differential expression analysis details. For conciseness, the labels of pairwise comparisons were coded in two letters: the first one represents the phenotype (M: mothers, F: fathers, P: paternal males, A: attackers), whereas the second one represents the structure (M: MPOA, N: NAc, L: LS). For instance, PLvAL refers to the comparison between the Paternal and Attackers phenotypes in the LS. DE: differentially expressed.

Registration Year

  • 2022
    937

Resource Types

  • Dataset
    937

Affiliations

  • Peking University
    937
  • Chinese Academy of Medical Sciences & Peking Union Medical College
    571
  • Zhejiang University
    533
  • Huazhong University of Science and Technology
    502
  • Capital Medical University
    490
  • Shanghai Jiao Tong University
    489
  • Sichuan University
    483
  • Chinese Academy of Sciences
    424
  • Fudan University
    419
  • University of Chinese Academy of Sciences
    373