31 Works

Additional file 9 of Genome-wide profiling of retroviral DNA integration and its effect on clinical pre-infusion CAR T-cell products

Lipei Shao, Rongye Shi, Yingdong Zhao, Hui Liu, Alexander Lu, Jinxia Ma, Yihua Cai, Tatyana Fuksenko, Alejandra Pelayo, Nirali N. Shah, James N. Kochenderfer, Scott M. Norberg, Christian Hinrichs, Steven L. Highfill, Robert P Somerville, Sandhya R. Panch, Ping Jin & David F. Stroncek
Additional file 9: Table S4. Differential integration sites at gene locus based on clinical outcomes.

Additional file 1 of Integrated metabolomic and transcriptomic analyses of the synergistic effect of polymyxin–rifampicin combination against Pseudomonas aeruginosa

Mohd Hafidz Mahamad Maifiah, Yan Zhu, Brian T. Tsuji, Darren J. Creek, Tony Velkov & Jian Li
Additional file 1: Table S1. Significantly changed metabolites at 15 min. Table S2. Significantly changed metabolites at 1 h. Table S3. Significantly changed metabolites at 4 h. Table S4. Significantly changed metabolites at 24 h. Table S5. DEGs induced by polymyxin B at 1 h. Table S6. DEGs induced by rifampicin B at 1 h. Table S7. DEGs induced by the combination of polymyxin B and rifampicin at 1 h. Table S8. DEGs induced by...

Additional file 11 of Multicohort transcriptome analysis of whole blood identifies robust human response signatures in Plasmodium falciparum infections

Yan-hui Zhang, Xin-zhuan Su, Jian Li, Jia-jian Shi & Li-hua Xie
Additional file 11: Table S2. The upregulated genes in malaria-infected relative to noninfected individuals in the discovery datasets.

Additional file 10 of Multicohort transcriptome analysis of whole blood identifies robust human response signatures in Plasmodium falciparum infections

Yan-hui Zhang, Xin-zhuan Su, Jian Li, Jia-jian Shi & Li-hua Xie
Additional file 10: Table S1. The subsets of genes and immune cell types identified from the ImmPort database.

Additional file 12 of Multicohort transcriptome analysis of whole blood identifies robust human response signatures in Plasmodium falciparum infections

Yan-hui Zhang, Xin-zhuan Su, Jian Li, Jia-jian Shi & Li-hua Xie
Additional file 12: Table S3. The downregulated genes in malaria-infected relative to noninfected individuals in the discovery datasets.

Additional file 12 of Multicohort transcriptome analysis of whole blood identifies robust human response signatures in Plasmodium falciparum infections

Yan-hui Zhang, Xin-zhuan Su, Jian Li, Jia-jian Shi & Li-hua Xie
Additional file 12: Table S3. The downregulated genes in malaria-infected relative to noninfected individuals in the discovery datasets.

Protective effects of psoralen polymer lipid nanoparticles on doxorubicin - induced myocardial toxicity

Fansu Meng, Yong Ouyang, Qianqian Ma, Manling Du, Hui Liu, Yong Zhuang, Mujuan Pang, Tiange Cai & Yu Cai
Abstract Doxorubicin (DOX) induced myocardial toxicity may limit its therapeutic use in clinic. Psoralen (PSO), a major active tricyclic furocoumarin extracted from Psoralea corylifolia, is widely used as an antineoplastic agent in treatment of leukemia and other cancers. This study is aim to find the protective effect of psoralen polymer lipid nanoparticles (PSO-PLN) on doxorubicin-induced myocardial toxicity in mice. The model of myocardial toxicity induced by DOX was established. The experiment was divided into 6...

Additional file 11 of Evolution and functional analysis of the GRAS family genes in six Rosaceae species

Yibo Bai, Hui Liu, Kaikai Zhu & Zong-Ming Cheng
Additional file 11: Table S1. Total of 333 GRAS genes were identified in six Rosaceae species. Table S2. Ks values of six Rosaceae species. Table S3. Duplication events of six Rosaceae species. Table S4. ka/Ks values of six Rosaceae species. Table S5. Primers used to detect drought stress and salt stress gene expression.

Protective effects of psoralen polymer lipid nanoparticles on doxorubicin - induced myocardial toxicity

Fansu Meng, Yong Ouyang, Qianqian Ma, Manling Du, Hui Liu, Yong Zhuang, Mujuan Pang, Tiange Cai & Yu Cai
Abstract Doxorubicin (DOX) induced myocardial toxicity may limit its therapeutic use in clinic. Psoralen (PSO), a major active tricyclic furocoumarin extracted from Psoralea corylifolia, is widely used as an antineoplastic agent in treatment of leukemia and other cancers. This study is aim to find the protective effect of psoralen polymer lipid nanoparticles (PSO-PLN) on doxorubicin-induced myocardial toxicity in mice. The model of myocardial toxicity induced by DOX was established. The experiment was divided into 6...

Characteristic of decreased bacterial diversity in psoriasis

Tong Su, Fang Liu, Cai-Xia Kou, Hai-Bo Liu, Sheng-Jing Xu, Dong-Yan Zhang, Fan Wei-Xin, Chao Fang & Min Zhang
ABSTRACT Disturbance of commensal intestinal microbiota is related to chronic inflammatory dermatosis. We analyzed the diversity of the gut microbiota to characterize the biological variation of psoriasis (Ps). Significant differences of gut microbiome profiles were revealed in murine model with psoriasis by sequencing 16S rRNA V3-V4 variable region. Group comparisons included the imiquimod cream (IMQ group, n=8), the imiquimod cream and antibiotics (ATB) (PC+IMQ group, n=8) and the healthy control (CTRL group, n=8). The gut...

Characteristic of decreased bacterial diversity in psoriasis

Tong Su, Fang Liu, Cai-Xia Kou, Hai-Bo Liu, Sheng-Jing Xu, Dong-Yan Zhang, Fan Wei-Xin, Chao Fang & Min Zhang
ABSTRACT Disturbance of commensal intestinal microbiota is related to chronic inflammatory dermatosis. We analyzed the diversity of the gut microbiota to characterize the biological variation of psoriasis (Ps). Significant differences of gut microbiome profiles were revealed in murine model with psoriasis by sequencing 16S rRNA V3-V4 variable region. Group comparisons included the imiquimod cream (IMQ group, n=8), the imiquimod cream and antibiotics (ATB) (PC+IMQ group, n=8) and the healthy control (CTRL group, n=8). The gut...

VIBRATION CHARACTERISTICS, CHEMICAL BONDS AND WEAK INTERACTIONS OF 4- AND 5-HYDROXYSALICYLIC ACID INVESTIGATED BY TERAHERTZ SPECTROSCOPY AND DENSITY FUNCTIONAL THEORY

Yuan Tang, Zhi Li, Yan Guo, Xianhua Yin, Shan Tu & Dapeng Zhang
The terahertz (THz) absorption spectra of 4- and 5-hydroxysalicylic acid were measured by terahertz time-domain spectroscopy (THz-TDS) in the range of 0.4-2.8 THz. The unit cells of both were calculated by density functional theory (DFT), and the theoretical simulation and experimental data were basically in agreement. To further interpret the origin of the characteristic absorption peaks, vibration characteristics and interactions of the unit cell model were analyzed by using potential energy distribution (PED) and interaction...

Additional file 7 of Genome-wide profiling of retroviral DNA integration and its effect on clinical pre-infusion CAR T-cell products

Lipei Shao, Rongye Shi, Yingdong Zhao, Hui Liu, Alexander Lu, Jinxia Ma, Yihua Cai, Tatyana Fuksenko, Alejandra Pelayo, Nirali N. Shah, James N. Kochenderfer, Scott M. Norberg, Christian Hinrichs, Steven L. Highfill, Robert P Somerville, Sandhya R. Panch, Ping Jin & David F. Stroncek
Additional file 7: Table S2. Differentially expressed genes in non-transduced and transduced CAR T-cell products.

Additional file 8 of Genome-wide profiling of retroviral DNA integration and its effect on clinical pre-infusion CAR T-cell products

Lipei Shao, Rongye Shi, Yingdong Zhao, Hui Liu, Alexander Lu, Jinxia Ma, Yihua Cai, Tatyana Fuksenko, Alejandra Pelayo, Nirali N. Shah, James N. Kochenderfer, Scott M. Norberg, Christian Hinrichs, Steven L. Highfill, Robert P Somerville, Sandhya R. Panch, Ping Jin & David F. Stroncek
Additional file 8: Table S3. Differential alternative splicing transcripts with viral integration.

Lightweight design of a clamp band joint via a constrained sequential approximate optimization method in the irregular design domain

Baoshi Yu, Yongjun Lei, Zhixiang Wang, Dapeng Zhang & Haiyang Li
The clamp band joint (CBJ) is a multi-component and complex device for connecting and separating satellites from launch vehicles. In this article, the pre-tightening and connection process are analysed sequentially through an implicit–explicit calculation method. Because of the time-consuming nonlinear analysis, a constrained sequential approximate optimization (CSAO) method in the irregular design domain is proposed for the lightweight optimization design of CBJs. A novel constrained space-filling and non-collapsing sequential sampling method is adopted to address...

Establishment of a subcutaneous adipogenesis model and distinct roles of LKB1 regulation on adipocyte lipid accumulation in high-altitude Bos grunniens

Yongqi Yue, Yonglin Hua, Jing Zhang, Yu Guo, Dan Zhao, Wentao Huo, Yan Xiong, Fenfen Chen, Yaqiu Lin, Xianrong Xiong & Jian Li
The domestic yak was regarded as a valuable model to explore the molecular mechanism of high-altitude animal adaptation, including the extreme tolerance of starvation and cold stress, which is closely associated with specifically seasonal deposition and metabolism of subcutaneous adipose tissue. However, the key regulators for these processes remain largely unknown. Here, the yak adipogenesis model in vitro was established and liver kinase b1 (LKB1) was regarded as a key negative regulator involved in yak...

Additional file 6 of Genome-wide profiling of retroviral DNA integration and its effect on clinical pre-infusion CAR T-cell products

Lipei Shao, Rongye Shi, Yingdong Zhao, Hui Liu, Alexander Lu, Jinxia Ma, Yihua Cai, Tatyana Fuksenko, Alejandra Pelayo, Nirali N. Shah, James N. Kochenderfer, Scott M. Norberg, Christian Hinrichs, Steven L. Highfill, Robert P Somerville, Sandhya R. Panch, Ping Jin & David F. Stroncek
Additional file 6: Table S1. Characteristics of CAR T-cell products.

Additional file 6 of Genome-wide profiling of retroviral DNA integration and its effect on clinical pre-infusion CAR T-cell products

Lipei Shao, Rongye Shi, Yingdong Zhao, Hui Liu, Alexander Lu, Jinxia Ma, Yihua Cai, Tatyana Fuksenko, Alejandra Pelayo, Nirali N. Shah, James N. Kochenderfer, Scott M. Norberg, Christian Hinrichs, Steven L. Highfill, Robert P Somerville, Sandhya R. Panch, Ping Jin & David F. Stroncek
Additional file 6: Table S1. Characteristics of CAR T-cell products.

Additional file 7 of Genome-wide profiling of retroviral DNA integration and its effect on clinical pre-infusion CAR T-cell products

Lipei Shao, Rongye Shi, Yingdong Zhao, Hui Liu, Alexander Lu, Jinxia Ma, Yihua Cai, Tatyana Fuksenko, Alejandra Pelayo, Nirali N. Shah, James N. Kochenderfer, Scott M. Norberg, Christian Hinrichs, Steven L. Highfill, Robert P Somerville, Sandhya R. Panch, Ping Jin & David F. Stroncek
Additional file 7: Table S2. Differentially expressed genes in non-transduced and transduced CAR T-cell products.

Lightweight design of a clamp band joint via a constrained sequential approximate optimization method in the irregular design domain

Baoshi Yu, Yongjun Lei, Zhixiang Wang, Dapeng Zhang & Haiyang Li
The clamp band joint (CBJ) is a multi-component and complex device for connecting and separating satellites from launch vehicles. In this article, the pre-tightening and connection process are analysed sequentially through an implicit–explicit calculation method. Because of the time-consuming nonlinear analysis, a constrained sequential approximate optimization (CSAO) method in the irregular design domain is proposed for the lightweight optimization design of CBJs. A novel constrained space-filling and non-collapsing sequential sampling method is adopted to address...

Additional file 2 of Quantifying substantial carcinogenesis of genetic and environmental factors from measurement error in the number of stem cell divisions

Xinhui Liu, Jifeng Yang, Hongkai Li, Qing Wang, Yuanyuan Yu, Xiaoru Sun, Shucheng Si, Lei Hou, Lu Liu, Fan Yang, Ran Yan, Yifan Yu, Zhentao Fu, Zilong Lu, Dejin Li, Hao Xue, Xiaolei Guo, Fuzhong Xue & Xiaokang Ji
Additional file 2: Table S1. Ranked matrix of LCR in global scope and the contribution of the genetic and environmental factors on the variation in cancer risk. Table S2. Ranked matrix of LCR in national-wide of China and the contribution of the genetic and environmental factors on the variation in cancer risk. Table S3. Ranked matrix of LCR in counties of Shandong province, China and the contribution of the genetic and environmental factors on the...

Establishment of a subcutaneous adipogenesis model and distinct roles of LKB1 regulation on adipocyte lipid accumulation in high-altitude Bos grunniens

Yongqi Yue, Yonglin Hua, Jing Zhang, Yu Guo, Dan Zhao, Wentao Huo, Yan Xiong, Fenfen Chen, Yaqiu Lin, Xianrong Xiong & Jian Li
The domestic yak was regarded as a valuable model to explore the molecular mechanism of high-altitude animal adaptation, including the extreme tolerance of starvation and cold stress, which is closely associated with specifically seasonal deposition and metabolism of subcutaneous adipose tissue. However, the key regulators for these processes remain largely unknown. Here, the yak adipogenesis model in vitro was established and liver kinase b1 (LKB1) was regarded as a key negative regulator involved in yak...

VIBRATION CHARACTERISTICS, CHEMICAL BONDS AND WEAK INTERACTIONS OF 4- AND 5-HYDROXYSALICYLIC ACID INVESTIGATED BY TERAHERTZ SPECTROSCOPY AND DENSITY FUNCTIONAL THEORY

Yuan Tang, Zhi Li, Yan Guo, Xianhua Yin, Shan Tu & Dapeng Zhang
The terahertz (THz) absorption spectra of 4- and 5-hydroxysalicylic acid were measured by terahertz time-domain spectroscopy (THz-TDS) in the range of 0.4-2.8 THz. The unit cells of both were calculated by density functional theory (DFT), and the theoretical simulation and experimental data were basically in agreement. To further interpret the origin of the characteristic absorption peaks, vibration characteristics and interactions of the unit cell model were analyzed by using potential energy distribution (PED) and interaction...

Additional file 1 of Integrated metabolomic and transcriptomic analyses of the synergistic effect of polymyxin–rifampicin combination against Pseudomonas aeruginosa

Mohd Hafidz Mahamad Maifiah, Yan Zhu, Brian T. Tsuji, Darren J. Creek, Tony Velkov & Jian Li
Additional file 1: Table S1. Significantly changed metabolites at 15 min. Table S2. Significantly changed metabolites at 1 h. Table S3. Significantly changed metabolites at 4 h. Table S4. Significantly changed metabolites at 24 h. Table S5. DEGs induced by polymyxin B at 1 h. Table S6. DEGs induced by rifampicin B at 1 h. Table S7. DEGs induced by the combination of polymyxin B and rifampicin at 1 h. Table S8. DEGs induced by...

Additional file 8 of Genome-wide profiling of retroviral DNA integration and its effect on clinical pre-infusion CAR T-cell products

Lipei Shao, Rongye Shi, Yingdong Zhao, Hui Liu, Alexander Lu, Jinxia Ma, Yihua Cai, Tatyana Fuksenko, Alejandra Pelayo, Nirali N. Shah, James N. Kochenderfer, Scott M. Norberg, Christian Hinrichs, Steven L. Highfill, Robert P Somerville, Sandhya R. Panch, Ping Jin & David F. Stroncek
Additional file 8: Table S3. Differential alternative splicing transcripts with viral integration.

Registration Year

  • 2022
    31

Resource Types

  • Dataset
    31

Affiliations

  • National Center for AIDS/STD Control and Prevention,China CDC
    30
  • Nanjing Agricultural University
    26
  • Huazhong University of Science and Technology
    25
  • Zhejiang University
    16
  • Lanzhou University
    15
  • Chinese Academy of Medical Sciences & Peking Union Medical College
    15
  • Anhui Medical University
    14
  • Shandong University
    13
  • Chinese Academy of Sciences
    13
  • Shanghai Jiao Tong University
    11