470 Works

MOESM1 of Comparative study of excretoryâ secretory proteins released by Schistosoma mansoni-resistant, susceptible and naĂŻve Biomphalaria glabrata

Conor Fogarty, Min Zhao, Donald McManus, Mary Duke, Scott Cummins & Tianfang Wang
Additional file 1: Database S1. The B. glabrata protein database used in the proteomic data analysis.

Additional file 8 of Comparative study of excretory–secretory proteins released by Schistosoma mansoni-resistant, susceptible and naïve Biomphalaria glabrata

Conor E. Fogarty, Min Zhao, Donald P. McManus, Mary G. Duke, Scott F. Cummins & Tianfang Wang
Additional file 8: Table S5. A list of the total proteins, unique proteins and corresponding peptides identified in susceptible B. glabrata SCW with reference to the S. mansoni proteome, and enriched GO terms related to the proteins.

Variations in leaf economics spectrum traits for an evergreen coniferous species: Tree size dominates over environment factors

Zhili Liu, Kouki Hikosaka, Fengri Li & Guangze Jin
Many leaf traits strongly vary with tree size and environmental factors, but the importance of these factors to intraspecific variations of leaf traits in forest trees have rarely been simultaneously evaluated. We measured needle longevity and specific leaf area (SLA) and nitrogen (N) content of every needle age (0 to 4 year old) for 65 individuals with 0.3-100 cm diameter at breast height (DBH) for an evergreen coniferous species, Pinus koraiensis Sieb. et Zucc., in...

Data from: Determination of the most effective design for the measurement of photosynthetic light-response curves for planted Larix olgensis trees

Qiang Liu, Weiwei Jia & Fengri Li
A photosynthetic light-response (PLR) curve is a mathematical description of a single biochemical process and has been widely applied in many eco-physiological models. To date, many PLR measurement designs have been suggested, although their differences have rarely been explored, and the most effective design has not been determined. In this study, we measured three types of PLR curves (High, Middle and Low) from planted Larix olgensis trees by setting 31 photosynthetically active radiation (PAR) gradients....

Using BART to Perform Pareto Optimization and Quantify its Uncertainties

Akira Horiguchi, Thomas J. Santner, Ying Sun & Matthew T. Pratola
Techniques to reduce the energy burden of an industrial ecosystem often require solving a multiobjective optimization problem. However, collecting experimental data can often be either expensive or time-consuming. In such cases, statistical methods can be helpful. This article proposes Pareto Front (PF) and Pareto Set (PS) estimation methods using Bayesian Additive Regression Trees (BART), which is a nonparametric model whose assumptions are typically less restrictive than popular alternatives, such as Gaussian Processes (GPs). These less...

Moisture and mold-proof characteristics of surface modified wood for musical instrument soundboards

Caiping Xu, Zhenbo Liu, Wanli Li & Xingyun Li
Wood is the major material for musical instrument soundboards fabrication on account of practical and cultural reasons. However, as a natural material, wood is easy to be degraded due to moisture or fungi corrosion. The traditional wood protection methods are normally meant for the structural materials, which might not suitable for the soundboard materials. Therefore, in this work, a novel nanomaterial-based modification method was applied to effectively protect wood from moisture and fungi, without causing...

Joint control of plant ecological strategy by climate, regeneration mode, and ontogeny in Northeastern Chinese forests

Xiangjun Zhang & Shuli Wang
Research on how plant ecological strategies (competitive, stress-tolerant, or ruderal) vary within species may improve our understanding of plant and community responses to climate warming and also successional changes. With increasing temperature, the importance of ruderal (R) and stress-tolerance (S) components is hypothesized to decrease, while the strength of the competitive (C) component should increase. Offshoots and younger plants are predicted to have greater R and smaller S components. Leaf area, leaf dry matter content,...

Morphology and phylogeny of two new Thalassiosiroid taxa (Bacillariophyceae), with two marginal rimoportulae

Biaobiao Niu, Yaqiong Guo, Nina Lundholm & Yang Li
Thalassiosira and related taxa i.e. the taxa within Thalassiosirales are among the most abundant and widespread diatoms. The vast majority have one marginal rimoportula, but very few always have two. The knowledge on Thalassiosiroid taxa in Chinese waters is restricted, and to explore the diversity, monoclonal strains were established from southern Chinese coastal waters. Morphological data were based on light and scanning electron microscopy. The D1‒D3 region of the ribosomal large subunit (LSU) and the...

Comprehensive analysis of PPPCs family reveals the clinical significance of PPP1CA and PPP4C in breast cancer

Wenjun Xie, Ying Sun, Yu Zeng, Linfei Hu, Jingtai Zhi, Hang Ling, Xiangqian Zheng, Xianhui Ruan & Ming Gao
The phosphoprotein phosphatase catalytic subunit (PPPCs) family has been shown to play an important role in the development and progression of various malignancies, but its expression patterns and biological functions in breast cancer (BC) remain unclear. Therefore, we aimed to investigate the clinical significance and biological functions of the PPPCs family to understand its possible significance in the diagnosis, prognosis and treatment of breast cancer. We comprehensively investigated the expression levels, diagnostic accuracy, prognostic outcomes,...

N(6)-adenosine-methyltransferase-14 promotes glioma tumorigenesis by repressing argininosuccinate synthase 1 expression in an m6A-dependent manner

You-Qing Miao, Wei Chen, Jianfeng Zhou, Qiyang Shen, Ying Sun, Tao Li & Sheng-Chan Wang
Glioma is one of the leading causes of tumor-related deaths worldwide, but its potential mechanism remains unclear. This study aimed to explore the biological role and potential mechanism of argininosuccinate synthase 1 (ASS1) in glioma. The relative expression levels of ASS1 in glioma specimens and cell lines were calculated by quantitative reverse transcription-polymerase chain reaction (qRT-PCR) and Western blotting. The biological functions of ASS1 were demonstrated using the 5-ethynyl-2ʹ-deoxyuridine (EdU) assay, transwell assay, and in...

Arabidopsis Glutathione-S-Transferases GSTF11 and GSTU20 function in Aliphatic Glucosinolate Biosynthesis

Aiqin Zhang
GSH conjugation with intermediates is required for the biosynthesis of glucosinolate (GSL) by serving as a sulfur supply. Glutathione-S-transferases (GSTs) primarily work on GSH conjugation, suggesting their involvement in GSL metabolism. Although several GSTs, including GSTF11 and GSTU20, have been recently postulated to act in GSL biosynthesis, molecular evidence is lacking. Here, we demonstrated that GSTF11 and GSTU20 play nonredundant, although partially overlapping, roles in aliphatic GSL biosynthesis. In addition, GSTU20 plays a more important...

Cenozoic rifting and inversion of Beibuwan Basin and its linkage with the strike-slip movement along the Ailao Shan-Red River Shear Zone

Yanjun Cheng, Zhiping Wu, Jie Zhang, Yuqing Liu, Zhengkai Wang & Yining Dai
The Cenozoic Beibuwan Basin is located along the eastern margin of the Ailao Shan Red River Shear Zone (ASRRSZ). The rifting and inversion processes of this basin provide important clues to the mechanism by which extrusion tectonics drive continental rifting and inversion development. However, the rifting and inversion of this basin remain ambiguous. Here, we employ seismic data, information about the time and displacement of faulting, syn-rift fault and isopach maps to analyse the Cenozoic...

Data from: Driving factors on greenhouse gas emissions in permafrost region of Daxing’an Mountains, Northeast China

Weifeng Gao, Dawen Gao, Tijiu Cai & Hong Liang
Permafrost regions are an important source of greenhouse gases. However, the effects of different permafrost wetland types on greenhouse gas emissions and the driving factors are still unclear in the permafrost region. Here, we selected three typical permafrost wetlands from the Daxing’an Mountains to investigate the effects of permafrost wetland types on greenhouse gas emissions. The cumulative N2O, CO2, and CH4 emissions were 84–122, 657,942–1,446,121, and 173–16,924 kg km−2, respectively. The linear mixed effects model...

Aralia elata genome and annotation

Yu Wang
We report a chromosome-level genome of Aralia elata with a total length of 1.08 Gb and a contig N50 of 1.2 Mb using SMRT, HiC, and next-generation sequencing. The Aralia elata genome is the first chromosome-level genome of genus Aralia. This dataset also includes the annotation of Aralia elata genome and the gene expression profiles.

LINC00857 regulated by ZNF460 enhances the expression of CLDN12 by sponging miR-150-5p and recruiting SRSF1 for alternative splicing to promote epithelial-mesenchymal transformation of pancreatic adenocarcinoma cells

Yong Zhang, Yuan Fang, Lijie Ma, Jing Xu, Chentao Lv, Li Deng & Guanghui Zhu
Recent research unveiled that LINC00857 plays a regulatory role in multiple human cancers, such as lung adenocarcinoma and gastric cancer. Nevertheless, the function of LINC00857 in pancreatic adenocarcinoma (PAAD) remains unclear. This study concentrates on LINC00857 to discuss the relevant molecular mechanism of this gene in PAAD. Quantitative reverse transcription polymerase chain reaction (RT-qPCR) and western blot were implemented for measuring the expressions of RNAs and proteins. Wound healing and Transwell assays were used to...

Feasibility of urban bird and nest amount evaluation by the street view image virtual survey

Tian Panli, Panli Tian, Chentao Liang, Huimei Wang & Wenjie Wang
The use of Street View maps in urban bird and nest surveys is worth exploring. Using Baidu Street-View (BSV) map, 49338 seamless spherical photos of 2741 sites were collected in Qingdao. Study evaluated the effectiveness and reproducibility of birds and nests using three observation angles and four experimenters. The BSV method and citizen science data were compared to evaluate their spatial distribution consistency. The BSV time machine is used to assess them time dynamics. The...

LncRNA-UCA1 regulates lung adenocarcinoma progression through competitive binding to miR-383

Li Tang, Sheng Wang, Yapeng Wang, Kang Li & Qiang Li
The present study aimed to assess the role of the long non-coding RNA-urothelial cancer associated 1 (lncRNA-UCA1)/microRNA (miR)-383/vascular endothelial growth factor A (VEGFA) axis in regulating lung adenocarcinoma physiology through in vivo and in vitro experiments. The expression profile of lncRNA-UCA1 was analyzed by genome-wide analysis from GSE146459. The cell counting Kit-8, colony formation, wound healing and transwell assays were performed to evaluate the effects of lncRNA-UCA1 in vitro. In addition, luciferase reporter assays were...

Utilizing network pharmacological analysis to investigate the key targets and mechanisms of kaempferol against oxaliplatin-induced neurotoxicity

Hongxing Wang, Jing Quan, Youming Deng, Jie Chen, Ke Zhang & Zhan Qu
This study investigated the pharmacological mechanism of kaempferol in the treatment of oxaliplatin-induced neuropathic pain by network pharmacological method and cells experiment. The kaempferol and disease target genes were obtained from several databases, including TCMSP, SwissTargetPrediction, GeneCards, and CTD. Then, the common target genes of drugs and diseases were obtained using Venny online tools. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) functional analyses were carried out to obtain the enriched molecular...

Ecological relationships among habitat type, food nutrients, parasites and hormones in wild boar during winter

Dongqi Liu
Habitat quality and parasite assembly influence wildlife health, and they are key indicators of health and survivability of wildlife populations. To investigate the potential ecological relationships among habitat type, food nutrients, parasites and hormones in wild boar (Sus scrofa), we collected samples of wild boar feces and available plants in their habitat by line transects during winter. Along transects, we identified the composition of plants foraged by wild boar and measured the content of nutrients...

UXT attenuates the CGAS-STING1 signaling by targeting STING1 for autophagic degradation

Mingyu Pan, Yue Yin, Tongyu Hu, Xinxia Wang, Tian Jia, Jing Sun, Quanyi Wang, Wei Meng, Juanjuan Zhu, Chunsun Dai, Haiyang Hu & Chen Wang
STING1 (stimulator of interferon response cGAMP interactor 1), the pivotal adaptor protein of CGAS (cyclic GMP-AMP synthase)-STING1 signaling, is critical for type I IFN production of innate immunity. However, excessive or prolonged activation of STING1 is associated with autoinflammatory and autoimmune diseases. Thus, preventing STING1 from over-activation is important to maintain immune homeostasis. Here, we reported that UXT (ubiquitously expressed prefoldin like chaperone), a small chaperone-like protein, was essential to prevent the excessive activation of...

Autophagy loss impedes cancer-associated fibroblast activation via downregulating proline biosynthesis

Jingru Bai, Tong Liu, Bo Tu, Meng Yuan, Zhaoqi Shu, Minghe Fan, Sihan Huo, Yuyao Guo, Lina Wang, Hua Wang & Ying Zhao
Cancer-associated fibroblasts (CAFs) are considered one of the most critical stromal cells that interact with pancreatic ductal adenocarcinoma (PDAC) and promote tumor growth, metastasis, and treatment resistance. Previous studies illustrated macroautophagy/autophagy contributes to CAF activation during tumor progression. Here in our study, we found that autophagy deficiency in CAFs impedes CAF activation by inhibiting proline biosynthesis and collagen production. Furthermore, we uncovered that autophagy promotes proline biosynthesis through mitophagy-mediated regulation of NADK2 (NAD kinase 2,...

Additional file 3 of The effectiveness of case management for cancer patients: an umbrella review

Nina Wang, Jia Chen, Wenjun Chen, Zhengkun Shi, Huaping Yang, Peng Liu, Xiao Wei, Xiangling Dong, Chen Wang, Ling Mao & Xianhong Li
Additional file 3.

Additional file 11 of System analysis based on the pyroptosis-related genes identifies GSDMC as a novel therapy target for pancreatic adenocarcinoma

Cheng Yan, Yandie Niu, Feng Li, Wei Zhao & Liukai Ma
Additional file 11: Drugs with significant differences in IC50 values between high-risk and low-risk groups.

Additional file 11 of System analysis based on the pyroptosis-related genes identifies GSDMC as a novel therapy target for pancreatic adenocarcinoma

Cheng Yan, Yandie Niu, Feng Li, Wei Zhao & Liukai Ma
Additional file 11: Drugs with significant differences in IC50 values between high-risk and low-risk groups.

Additional file 2 of Exploring AI-2-mediated interspecies communications within rumen microbial communities

Xiaozhen Liu, Qinmeng Liu, Sihuai Sun, Hengxi Sun, Yao Wang, Xihui Shen & Lei Zhang
Additional file 2: Table S2. The rumen microbiota and the presence of quorum sensing molecules.

Registration Year

  • 2023
  • 2022
  • 2021
  • 2020
  • 2019
  • 2018
  • 2017

Resource Types

  • Dataset


  • Northeast Forestry University
  • Chinese Academy of Medical Sciences & Peking Union Medical College
  • Fudan University
  • Shanghai Jiao Tong University
  • Capital Medical University
  • Sichuan University
  • Huazhong University of Science and Technology
  • Zhejiang University
  • Chinese Academy of Sciences
  • Nanjing Medical University