105 Works
Saliva proteomic profile of early childhood caries and caries-free children
Bethania Paludo Oliveira, Marília Afonso Rabelo Buzalaf, Natália Caldeira Silva, Talita Mendes Oliveira Ventura, Júlia Toniolo & Jonas Almeida Rodrigues
Saliva plays an important antimicrobial role and it is related to the pathogenesis of early childhood caries (ECC). The aim of this study was to compare the proteomic profile of unstimulated saliva of children aged 3–5 years who had ECC and caries-free (CF) children. After the saliva collection from 20 children (ECC: n = 10; CF: n = 10), the samples were processed for proteomic analysis on a mass spectrometer. 1638 proteins were identified, of...
Individual and species variation in mixed-species aggregations of harvestmen
Ignacio Escalante, Marisol Domínguez, Daisy Gómez-Ruíz & Glauco Machado
This dataset is associated with the published paper Escalante, I, M Domínguez, D Gómez-Ruiz, and G Machado. Benefits and costs of multi-specific aggregations in harvestmen (Arachnida: Opiliones). Frontiers in Ecology and Evolution (DOI 10.3389/fevo.2021.766323). Please refer to the paper for the extensive explanations on the collection, analysis, presentation, and analyses of the data. We provide the first description of mixed-species roosting aggregations of seven species of the genus Prionostemma from Costa Rica. We surveyed several...
Data from: Analysis of the PEBP gene family and identification of a novel FLOWERING LOCUS T orthologue in sugarcane
Julien Venail, Paolo Da Silva Santos, Joao Manechini, Leonardo Alves, Maximiliano Scarpari, Thais Falcao, Elisson Romanel, Michael Brito, Renato Vicentini, Luciana Pinto & Stephen Jackson
Sugarcane (Saccharum spp.) is an important economic crop for both sugar and biomass, the yields of which are negatively affected by flowering. The molecular mechanisms controlling flowering in sugarcane are nevertheless poorly understood. RNA-seq data analysis and database searches have enabled a comprehensive description of the PEBP gene family in sugarcane. It is shown to consist of at least 13 FLOWERING LOCUS T (FT)-like genes, two MOTHER OF FT AND TFL (MFT)-like genes, and four...
A large-scale assessment of ant diversity across the Brazilian Amazon Basin: integrating geographic, ecological, and morphological drivers of sampling bias
Joudellys Andrade-Silva, Fabricio Baccaro, Lívia Prado, Benoit Guenard, Dan Warren, Jamie Kass, Evan Economo & Rogerio Silva
Tropical ecosystems are often biodiversity hotspots, and invertebrates represent the main underrepresented component of diversity in large-scale analyses. This problem is partly related to the scarcity of data widely available to conduct these studies and the lack of systematic organization of knowledge about invertebrates’ distributions in biodiversity hotspots. Here, we introduce and analyze a comprehensive data compilation of Amazonian ant diversity. Using records from 1817 to 2020 from both published and unpublished sources, we describe...
Dataset: Local hydrological conditions influence tree diversity and composition across the Amazon basin
Manuel J. Marca-Zevallos, Gabriel M. Moulatlet, Thaiane R. Sousa, Juliana Schietti, Luiz De Souza Coelho, José Ferreira Ramos, Diogenes De Andrade Lima Filho, Iêda Leão Amaral, Francisca Dionízia De Almeida Matos, Lorena M. Rincón, Juan David Cardenas Revilla, Marcelo Petratti Pansonato, Rogerio Gribel, Edelcilio Marques Barbosa, Ires Paula De Andrade Miranda, Luiz Carlos De Matos Bonates, Juan Ernesto Guevara, Rafael P. Salomão, Leandro Valle Ferreira, Dário Dantas Do Amaral, Nigel C.A. Pitman, Corine Vriesendorp, Tim R. Baker, Roel Brienen, Marcelo De Jesus Veiga Carim … & Flávia R.C. Costa
Tree diversity and composition in Amazonia are known to be strongly determined by the water supplied by precipitation. Nevertheless, within the same climatic regime, water availability is modulated by local topography and soil characteristics (hereafter referred to as local hydrological conditions), varying from saturated and poorly drained to well-drained and potentially dry areas. While these conditions may be expected to influence species distribution, the impacts of local hydrological conditions on tree diversity and composition remain...
Ultrasound reference values for peripheral nerve cross-sectional areas and indices in a sample of healthy individuals in Brazil
Glauber Voltan, Fred Bernardes-Filho, Helena Barbosa Lugão, Marcello Henrique Nogueira-Barbosa & Marco Andrey Cipriani Frade
Abstract Objective: To establish peripheral nerve cross-sectional area (CSA) reference values (absolute values, measures of asymmetry, and measures of focality) for healthy individuals in Brazil. Materials and Methods: Sixty-six healthy volunteers underwent high-resolution ultrasound of the peripheral nerves. We obtained CSA measurements for three peripheral nerves, at specific locations: the median nerve, in the carpal tunnel (MT); the ulnar nerve, at the cubital tunnel site (UT) and at the pre-tunnel site (UPT); and the common...
Reducing care time after implementing protocols for acute ischemic stroke: a systematic review
Karina Fonseca de Souza Leite, Samuel Ribeiro dos Santos, Rubia Laine de Paula Andrade, Mariana Gaspar Botelho Funari de Faria, Nanci Michele Saita, Ricardo Alexandre Arcêncio, Igor Simões da Silva Isaac, Carlos Eduardo Menezes de Rezende, Tereza Cristina Scatena Villa, Octavio Marques Pontes Neto & Aline Aparecida Monroe
Abstract Background The treatment of acute ischemic stroke with cerebral reperfusion therapy requires rapid care and recognition of symptoms. Objective To analyze the effectiveness of implementing protocols for acute ischemic stroke in reducing care time. Methods Systematic review, which was performed with primary studies in Portuguese, English, and Spanish published between 2011 and 2020. Inclusion criteria: study population should comprise people with acute ischemic stroke and studies should present results on the effectiveness of using...
Reducing care time after implementing protocols for acute ischemic stroke: a systematic review
Karina Fonseca de Souza Leite, Samuel Ribeiro dos Santos, Rubia Laine de Paula Andrade, Mariana Gaspar Botelho Funari de Faria, Nanci Michele Saita, Ricardo Alexandre Arcêncio, Igor Simões da Silva Isaac, Carlos Eduardo Menezes de Rezende, Tereza Cristina Scatena Villa, Octavio Marques Pontes Neto & Aline Aparecida Monroe
Abstract Background The treatment of acute ischemic stroke with cerebral reperfusion therapy requires rapid care and recognition of symptoms. Objective To analyze the effectiveness of implementing protocols for acute ischemic stroke in reducing care time. Methods Systematic review, which was performed with primary studies in Portuguese, English, and Spanish published between 2011 and 2020. Inclusion criteria: study population should comprise people with acute ischemic stroke and studies should present results on the effectiveness of using...
Evaluation of the Happy Child Program: a randomized study in 30 Brazilian municipalities
Iná S. Santos, Tiago N. Munhoz, Raquel Siqueira Barcelos, Cauane Blumenberg, Caroline Cardozo Bortolotto, Alicia Matijasevich, Cristiane Salum, Hernane Guimarães dos Santos Júnior, Letícia Marques, Luciano Correia, Marta Rovery de Souza, Pedro Israel Cabral de Lira, Vitor Pereira & Cesar G. Victora
Abstract The Happy Child Program (Programa Criança Feliz - PCF, in Portuguese) reaches 1.4 million Brazilian children under three years of age with home visits aimed at promoting neuropsychomotor development. Based on a conceptual model, PCF implementation and impact were evaluated in a randomized study in 30 municipalities. A total of 3,242 children were allocated to the intervention (IG) or control (CG) group, 80.0% of whom were prospectively followed up from late 2018 to late...
Social determinants of health and unfavourable outcome of tuberculosis treatment in the prison system
Melisane Regina Lima Ferreira, Rubia Laine de Paula Andrade, Pedro Augusto Bossonario, Regina Célia Fiorati, Ricardo Alexandre Arcêncio, Carlos Eduardo Menezes de Rezende, Nathalia Halax Orfão & Aline Aparecida Monroe
Abstract This article aims to analyze the unfavorable outcome of tuberculosis treatment among the population deprived of liberty by social determinants of health. This retrospective cohort was conducted in the states of Rondônia and São Paulo, Brazil, with inmates with tuberculosis notified between 2008 and 2017. Data were collected from SINAN and TB-WEB and analyzed by relative risk (RR) and confidence intervals (95%CI), which tested the association between the dependent variable (unfavorable outcome (deaths from...
Defibrillation Threshold Testing and Long-term Follow-up in Chagas Disease
Marco Paulo Cunha Campos, Luiz Fernando Gouveia Bernardes, João Paulo Chaves de Melo, Lucas Corsino dos Santos, Cristiano Honório Ribeiro Teixeira, Maria Licia Ribeiro Cury Pavão, Elerson Arfelli, Adilson Scorzoni Filho, Anis Rassi Jr, José A. Marin-Neto & André Schmidt
Abstract Background Sudden cardiac death is the most common cause of death in chronic Chagas cardiomyopathy (CCC). Because most CCC patients who are candidates for implantable cardioverter-defibrillators (ICD) meet criteria for high defibrillation threshold values, a defibrillator threshold test (DTT) is suggested. Objectives We investigated the use of DTT in CCC patients, focusing on deaths related to ICD and arrhythmic events, as well as treatment during long-term follow-up. Methods We retrospectively evaluated 133 CCC patients...
Subjective cognitive decline, mild cognitive impairment, and dementia - syndromic approach: recommendations of the Scientific Department of Cognitive Neurology and Aging of the Brazilian Academy of Neurology
Jerusa Smid, Adalberto Studart-Neto, Karolina Gouveia César-Freitas, Marcia Cristina Nascimento Dourado, Renata Kochhann, Breno José Alencar Pires Barbosa, Lucas Porcello Schilling, Márcio Luiz Figueiredo Balthazar, Norberto Anízio Ferreira Frota, Leonardo Cruz de Souza, Paulo Caramelli, Paulo Henrique Ferreira Bertolucci, Márcia Lorena Fagundes Chaves, Sonia Maria Dozzi Brucki, Ricardo Nitrini, Elisa de Paula França Resende & Francisco Assis Carvalho Vale
ABSTRACT This consensus, performed by the Brazilian Academy of Neurology (BAN) will approach practically how to evaluate patients with cognitive complaints and how to clinically and etiologically diagnose the three clinical syndromes associated with the different stages of cognitive decline: subjective cognitive decline (SCD), mild cognitive impairment (MCI), and dementia. This BAN consensus discusses SCD diagnosis for the first time, updates MCI and dementia diagnoses, recommends the adequate cognitive tests and the relevant etiological work-up...
Prevalence of cognitive impairment in Brazilian indigenous community from Amazonas
Anna Paula de Carvalho, Sonia Maria Dozzi Brucki, Ricardo Nitrini, Camila Carlos Bezerra, Fernanda Carini da Silva & Juliana Nery de Souza-Talarico
ABSTRACT. Studies on the prevalence of dementia in the indigenous population are still scarce worldwide. In the few available studies, prevalence evidence varies from low to very high, with early onset of the disease and high mortality rate after the initial diagnosis. Still, little is known about the rate of dementia in indigenous populations from low- and middle-income countries, where the dementia prevalence in the general population is estimated to increase significantly in the next...
Diagnosis of vascular cognitive impairment: recommendations of the scientific department of cognitive neurology and aging of the Brazilian Academy of Neurology
Breno José Alencar Pires Barbosa, José Ibiapina Siqueira Neto, Gilberto Sousa Alves, Felipe Kenji Sudo, Claudia Kimie Suemoto, Fernanda Tovar-Moll, Jerusa Smid, Lucas Porcello Schilling, Marcio Luiz Figueredo Balthazar, Norberto Anízio Ferreira Frota, Leonardo Cruz de Souza, Francisco Assis Carvalho Vale, Paulo Caramelli, Paulo Henrique Ferreira Bertolucci, Sonia Maria Dozzi Brucki, Ricardo Nitrini, Eliasz Engelhardt & Márcia Lorena Fagundes Chaves
ABSTRACT Since the publication of the latest recommendations for the diagnosis and treatment of Vascular Dementia by the Brazilian Academy of Neurology in 2011, significant advances on the terminology and diagnostic criteria have been made. This manuscript is the result of a consensus among experts appointed by the Scientific Department of Cognitive Neurology and Aging of the Brazilian Academy of Neurology (2020-2022). We aimed to update practical recommendations for the identification, classification, and diagnosis of...
Additional file 3 of MarineMetagenomeDB: a public repository for curated and standardized metadata for marine metagenomes
Muhammad Kabiru Nata’ala, Anderson P. Avila Santos, Jonas Coelho Kasmanas, Alexander Bartholomäus, João Pedro Saraiva, Sandra Godinho Silva, Tina Keller-Costa, Rodrigo Costa, Newton C. M. Gomes, André Carlos Ponce de Leon Ferreira de Carvalho, Peter F. Stadler, Danilo Sipoli Sanches & Ulisses Nunes da Rocha
Additional file 3. Table S3: Attributes chosen to represent different synonyms from SRAdb’s ‘sample_attribute’.
Additional file 4 of MarineMetagenomeDB: a public repository for curated and standardized metadata for marine metagenomes
Muhammad Kabiru Nata’ala, Anderson P. Avila Santos, Jonas Coelho Kasmanas, Alexander Bartholomäus, João Pedro Saraiva, Sandra Godinho Silva, Tina Keller-Costa, Rodrigo Costa, Newton C. M. Gomes, André Carlos Ponce de Leon Ferreira de Carvalho, Peter F. Stadler, Danilo Sipoli Sanches & Ulisses Nunes da Rocha
Additional file 4. Table S4: Marine ‘MarMDB’ attributes groups and their respective values.
Additional file 7 of MarineMetagenomeDB: a public repository for curated and standardized metadata for marine metagenomes
Muhammad Kabiru Nata’ala, Anderson P. Avila Santos, Jonas Coelho Kasmanas, Alexander Bartholomäus, João Pedro Saraiva, Sandra Godinho Silva, Tina Keller-Costa, Rodrigo Costa, Newton C. M. Gomes, André Carlos Ponce de Leon Ferreira de Carvalho, Peter F. Stadler, Danilo Sipoli Sanches & Ulisses Nunes da Rocha
Additional file 7. Table S7: Packages and their versions used for the WebApp.
Genetic diversity of Trypanosoma cruzi strains isolated from chronic chagasic patients and non-human hosts in the state of São Paulo, Brazil
Thiago Kury Moreno de Souza, Elizabeth Visone Nunes Westphalen, Sansão da Rocha Westphalen, Helena Hilomi Taniguchi, Carlos Roberto Elias, Gabriela Motoie, Ricardo Gava, Vera Lucia Pereira-Chioccola, Christina Terra Gallafrio Novaes, Noêmia Barbosa Carvalho, Edimar Alcides Bocchi, Fátima das Dores da Cruz, Mussya Cisotto Rocha, Samuel Katsuyuki Shinjo, Maria Aparecida Shikanai-Yasuda, Paola Andrea Ortiz, Marta Maria Geraldes Teixeira & José Eduardo Tolezano
BACKGROUND Trypanosoma cruzi shows an exuberant genetic diversity. Currently, seven phylogenetic lineages, called discrete typing units (DTUs), are recognised: TcI-TcVI and Tcbat. Despite advances in studies on T. cruzi and its populations, there is no consensus regarding its heterogeneity. OBJECTIVES This study aimed to perform molecular characterisation of T. cruzi strains, isolated in the state of São Paulo, to identify the DTUs involved and evaluate their genetic diversity. METHODS T. cruzi strains were isolated from...
Leukotriene B4 Loaded in Microspheres Inhibits Osteoclast Differentiation and Activation
Francine Lorencetti-Silva, Maya Fernanda Manfrin Arnez, João Pedro de Queiroz Thomé, Marcio Santos de Carvalho, Fabrício Kitazono de Carvalho, Alexandra Mussolino de Queiroz, Lúcia Helena Faccioli & Francisco Wanderley Garcia Paula-Silva
Abstract To investigate osteoclast formation in vivo and if leukotriene B4 (LTB4) loaded in microspheres (MS) could be used as a therapeutical strategy to promote a sustained delivery of the mediator and prevent osteoclast differentiation. Methods: In vivo, apical periodontitis was induced in mice to investigate osteoclast differentiation and signaling in absence of 5-lipoxygenase (5-LO). In vitro, LTB4-MS were prepared using an oil-in-water emulsion solvent extraction-evaporation process. Characterization and efficiency of LTB4 encapsulation were investigated....
Diagnosis of frontotemporal dementia: recommendations of the Scientific Department of Cognitive Neurology and Aging of the Brazilian Academy of Neurology
Leonardo Cruz de Souza, Mirna Lie Hosogi, Thais Helena Machado, Maria Teresa Carthery-Goulart, Mônica Sanches Yassuda, Jerusa Smid, Breno José Alencar Pires Barbosa, Lucas Porcello Schilling, Marcio Luiz Figueredo Balthazar, Norberto Anízio Ferreira Frota, Francisco Assis Carvalho Vale, Paulo Caramelli, Paulo Henrique Ferreira Bertolucci, Márcia Lorena Fagundes Chaves, Sonia Maria Dozzi Brucki, Ricardo Nitrini, Valéria Santoro Bahia & Leonel Tadao Takada
ABSTRACT “Frontotemporal dementia” (FTD) is a clinical syndrome characterized by the focal involvement of the frontal and/or temporal lobes. FTD has three clinical phenotypes: the behavioral variant and two linguistic subtypes, namely, non-fluent/agrammatic primary progressive aphasia (PPA-NF/A) and semantic PPA (PPA-S). FTD is the second most common cause of dementia in individuals under the age of 65 years. This article presents recommendations for the diagnosis of FTD in the Brazilian scenario, considering the three levels...
Diagnosis and management of Parkinson’s disease dementia and dementia with Lewy bodies: recommendations of the Scientific Department of Cognitive Neurology and Aging of the Brazilian Academy of Neurology
Jacy Bezerra Parmera, Vitor Tumas, Henrique Ballalai Ferraz, Mariana Spitz, Maira Tonidandel Barbosa, Jerusa Smid, Breno José Alencar Pires Barbosa, Lucas Porcello Schilling, Márcio Luiz Figueiredo Balthazar, Leonardo Cruz de Souza, Francisco Assis Carvalho Vale, Paulo Caramelli, Paulo Henrique Ferreira Bertolucci, Márcia Lorena Fagundes Chaves, Sonia Maria Dozzi Brucki, Ricardo Nitrini, Raphael Machado Castilhos & Norberto Anízio Ferreira Frota
ABSTRACT Parkinson’s disease dementia (PDD) and dementia with Lewy bodies (DLB) represent the second most common type of degenerative dementia in patients aged 65 years and older, leading to progressive cognitive dysfunction and impaired quality of life. This study aims to provide a consensus based on a systematic Brazilian literature review and a comprehensive international review concerning PDD and DLB. Moreover, we sought to report on and give recommendations about the best diagnostic approaches focusing...
Treatment of dementia: recommendations of the Scientific Department of Cognitive Neurology and Aging of the Brazilian Academy of Neurology
Paulo Caramelli, Valeska Marinho, Jerson Laks, Marcus Vinicius Della Coletta, Florindo Stella, Einstein Francisco Camargos, Jerusa Smid, Breno José Alencar Pires Barbosa, Lucas Porcello Schilling, Marcio Luiz Figueredo Balthazar, Norberto Anízio Ferreira Frota, Leonardo Cruz de Souza, Francisco Assis Carvalho Vale, Márcia Lorena Fagundes Chaves, Sonia Maria Dozzi Brucki, Ricardo Nitrini, Helen Bedinoto Durgante & Paulo Henrique Ferreira Bertolucci
ABSTRACT There is currently no cure for neurodegenerative or vascular dementias, but some pharmacological and non-pharmacological interventions may contribute to alleviate symptoms, slow disease progression and improve quality of life. Current treatment approaches are based on etiology, symptom profile and stage of dementia. This manuscript presents recommendations on pharmacological and non-pharmacological treatments of dementia due to Alzheimer’s disease, vascular cognitive impairment, frontotemporal dementia, Parkinson’s disease dementia, and dementia with Lewy bodies.
Treatment of dementia: recommendations of the Scientific Department of Cognitive Neurology and Aging of the Brazilian Academy of Neurology
Paulo Caramelli, Valeska Marinho, Jerson Laks, Marcus Vinicius Della Coletta, Florindo Stella, Einstein Francisco Camargos, Jerusa Smid, Breno José Alencar Pires Barbosa, Lucas Porcello Schilling, Marcio Luiz Figueredo Balthazar, Norberto Anízio Ferreira Frota, Leonardo Cruz de Souza, Francisco Assis Carvalho Vale, Márcia Lorena Fagundes Chaves, Sonia Maria Dozzi Brucki, Ricardo Nitrini, Helen Bedinoto Durgante & Paulo Henrique Ferreira Bertolucci
ABSTRACT There is currently no cure for neurodegenerative or vascular dementias, but some pharmacological and non-pharmacological interventions may contribute to alleviate symptoms, slow disease progression and improve quality of life. Current treatment approaches are based on etiology, symptom profile and stage of dementia. This manuscript presents recommendations on pharmacological and non-pharmacological treatments of dementia due to Alzheimer’s disease, vascular cognitive impairment, frontotemporal dementia, Parkinson’s disease dementia, and dementia with Lewy bodies.
Are recaptures of banded birds efficient at detecting altitudinal migrations in the Atlantic Forest?
Fabio Schunck, Marco Antonio Rego, Luís Fábio Silveira & Carlos Candia-Gallardo
ABSTRACT Altitudinal migration in birds comprises seasonal movements between breeding and non-breeding areas in mountainous regions, attributed to biotic and abiotic factors. Different authors have suggested the existence of altitudinal migration between high and low areas of the mountains of the Atlantic Forest, with movement from high to low during the winter when birds would be fleeing the cold and in search of food, but there is no documented evidence. Through recaptures of understory birds,...
Electrocardiographic Evaluation of Normal Newborns in the First Week of Life – Observational Study
Marina de Souza Pimenta, Nelson Samesima, Carlos Alberto Pastore, Vera Lucia Jornada Krebs, Gabriela Nunes Leal & Werther Brunow de Carvalho
Abstract Background The neonatal period is marked by major changes in the cardiovascular system, especially in the first week of life. Unlike the adult population, studies on electrocardiogram (ECG) data in the neonatal period are scarce. This is the first study to describe electrocardiographic changes in a cohort of newborns with normal echocardiograms. Objectives To analyze the electrocardiographic patterns of a population of full-term NB, without any cardiac morphological or functional anomalies, and compare the...
Affiliations
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Universidade de São Paulo80
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University of Sao Paulo25
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Universidade Federal de Minas Gerais16
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Helmholtz Centre for Environmental Research12
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Federal University of Technology – Paraná12
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University of Aveiro12
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University of Algarve12
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University of Lisbon12
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Leipzig University11
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Helmholtz Centre Potsdam - GFZ German Research Centre for Geosciences11