96 Works

Additional file 7 of Effective-component compatibility of Bufei Yishen formula III ameliorated COPD by improving airway epithelial cell senescence by promoting mitophagy via the NRF2/PINK1 pathway

Min-yan Li, Yan-qin Qin, Yan-ge Tian, Kang-chen Li, Brian G. Oliver, Xue-fang Liu, Peng Zhao & Jian-sheng Li
Additional file 7.

Additional file 9 of Folate regulates RNA m5C modification and translation in neural stem cells

Xiguang Xu, Zachary Johnson, Amanda Wang, Rachel L. Padget, James W. Smyth & Hehuang Xie
Additional file 9. Source codes used to generate figures.

Liver fluke (Opisthorchis viverrini) worm burdens and egg counts from humans in Thailand and Lao PDR

Thomas Crellen, Melissa Haswell, Paiboon Sithithaworn, Somphou Sayasone, Peter Odermatt, Poppy Lamberton, Simon Spencer & T. Deirdre Hollingsworth
Helminth transmission and morbidity are dependent on the number of mature parasites within a host, however, observing adult worms is impossible for many natural infections. An outstanding challenge is therefore relating routine diagnostics, such as faecal egg counts, to the underlying worm burden. This relationship is complicated by density-dependent fecundity (egg output per-worm reduces due to crowding at high burdens) and the skewed distribution of parasites (majority of helminths aggregated in a small fraction of...

Data from: Evaluating the foraging performance of individual honey bees in different environments with automated field RFID systems

Theotime Colin, Ryan J Warren, Stephen R Quarrell, Geoff R Allen & Andrew B Barron
Measuring the individual foraging performances of pollinators is crucial to guide environmental policies that aim at enhancing pollinator health and pollination services. Automated systems have been developed to track the activity of individual honey bees, but their deployment is extremely challenging. This has limited the assessment of individual foraging performances in full-strength bee colonies in the field. Most studies available to date have been constrained to use downsized bee colonies located in urban and suburban...

Data from: Variation in red fox Vulpes vulpes diet in five continents

Irene Castañeda, Tim S. Doherty, Patricia A. Fleming, Alyson M. Stobo-Wilson, John C. Z. Woinarski & Thomas M. Newsome
Understanding variation in the diet of widely distributed species can help us to predict how they respond to future environmental and anthropogenic changes. We studied the diet of the red fox Vulpes vulpes, one of the world’s most widely distributed carnivores. We compiled dietary data from 217 studies at 276 locations in five continents to assess how fox diet composition varied according to geographic location, climate, anthropogenic impact and sampling method. The diet of foxes...

Recent reconfiguration of an ancient developmental gene regulatory network in Heliocidaris Sea Urchins

Phillip Davidson, Haobing Guo, Abdull Massri, Jane Swart, Allison Edgar, Haobing Guo, Hannah Devens, Alejandro Berrio, Lingyu Wang, Demian Koop, Paula Cisternas, He Zhang, Yaloei Zhang, Maria Byrne, Guangyi Fan & Gregory Wray
Changes in developmental gene regulatory networks (dGRNs) underlie much of the diversity of life, but the evolutionary mechanisms that operate on interactions with these networks remain poorly understood. Closely related species with extreme phenotypic divergence provide a valuable window into the genetic and molecular basis for changes in dGRNs and their relationship to adaptive changes in organismal traits. Here we analyze genomes, epigenomes, and transcriptomes during early development in two sea urchin species in the...

Thermal tolerance of Arbacia lixula

Shawna Foo
As the ocean warms, the thermal tolerance of marine invertebrates is key to determining their distributional change, where acclimation to low pH may impact the thermal range of optimal development. We compared thermal tolerance of progeny from a low pH-acclimated sea urchin (Arbacia lixula) population from the CO2 vents of Ischia (Italy), and a nearby population living at ambient pH. The percentage of normally developing gastrulae and two-armed larvae were determined across 10 temperatures representing...

Additional file 1 of Incorporating a gender lens into nutrition and health-related policies in Fiji: analysis of policies and stakeholder perspectives

Briar L. McKenzie, Gade Waqa, Sarah Mounsey, Claire Johnson, Mark Woodward, Kent Buse, Anne Marie Thow, Rachael McLean & Jacqui Webster
Additional file 1: Supplementary table 1. Policy content analysis and WHO gender analysis, data extraction.

Total RNA sequencing of Phlebotomus chinensis sandflies in China revealed viral, bacterial, and eukaryotic microbes potentially pathogenic to humans

Jing Wang, Qin-yu Gou, Geng-yan Luo, Xin Hou, Guodong Liang & Mang Shi
Phlebotomus chinensis sandfly is a neglected insect vector in China that is well-known for carrying Leishmania. Recent studies have expanded its pathogen repertoire with two novel arthropod-borne phleboviruses capable of infecting humans and animals. Despite these discoveries, our knowledge of the general pathogen diversity and overall microbiome composition of this vector species is still very limited. Here we carried out a meta-transcriptomics analysis that revealed the actively replicating/transcribing RNA viruses, DNA viruses, bacteria, and eukaryotic...

Evolutionary changes in the chromatin landscape contribute to reorganization of a developmental gene network during rapid life history evolution in sea urchins

Phillip Davidson, Maria Byrne & Greg Wray
Chromatin configuration is highly dynamic during embryonic development in animals, exerting an important point of control in transcriptional regulation. Yet there exists remarkably little information about the role of evolutionary changes in chromatin configuration to the evolution of gene expression and organismal traits. Genome-wide assays of chromatin configuration, coupled with whole-genome alignments, can help address this gap in knowledge in several ways. In this study, we present a comparative analysis of regulatory element sequences and...

Long-term effectiveness of the midwifery initiated oral health-dental service program on maternal oral health knowledge, preventative dental behaviours and the oral health status of children in Australia

Ajesh George, Ariana Kong, Mariana S. Sousa, Amy Villarosa, Shilpi Ajwani, Hannah G. Dahlen, Sameer Bhole, Albert Yaacoub, Ravi Srinivas & Maree Johnson
The Midwifery Initiated Oral Health-Dental Service was developed to train midwives to promote maternal oral health, and a large trial showed it substantially improved the oral health, knowledge and behaviours of pregnant women. Evaluate the long-term effectiveness of the program (post-trial) on maternal oral health knowledge, dental behaviours, and early childhood caries in offspring. A prospective cohort study involving 204 women and children 3–4 years (followed after trial) was conducted in Sydney, Australia from 2017...

Additional file 2 of Folate regulates RNA m5C modification and translation in neural stem cells

Xiguang Xu, Zachary Johnson, Amanda Wang, Rachel L. Padget, James W. Smyth & Hehuang Xie
Additional file 2: Table 1. Library statistics.

An Approximated Collapsed Variational Bayes Approach to Variable Selection in Linear Regression

Chong You, John T. Ormerod, Xiangyang Li, Cheng Heng Pang & Xiao-Hua Zhou
In this work, we propose a novel approximated collapsed variational Bayes approach to model selection in linear regression. The approximated collapsed variational Bayes algorithm offers improvements over mean field variational Bayes by marginalizing over a subset of parameters and using mean field variational Bayes over the remaining parameters in an analogous fashion to collapsed Gibbs sampling. We have shown that the proposed algorithm, under typical regularity assumptions, (1) includes variables in the true underlying model...

Induction of significant neutralizing antibodies against SARS-CoV-2 by a highly attenuated pangolin coronavirus variant with a 104nt deletion at the 3'-UTR

Shanshan Lu, Shengdong Luo, Chang Liu, Muli Li, Xiaoping An, Mengzhe Li, Jun Hou, Huahao Fan, Panyong Mao, Yigang Tong & Lihua Song
SARS-CoV-2 related coronaviruses (SARS-CoV-2r) from Guangdong and Guangxi pangolins have been implicated in the emergence of SARS-CoV-2 and future pandemics. We previously reported the culture of a SARS-CoV-2r GX_P2V from Guangxi pangolins. Here we report the GX_P2V isolate rapidly adapted to Vero cells by acquiring two genomic mutations: an alanine to valine substitution in the nucleoprotein and a 104-nucleotide deletion in the hypervariable region (HVR) of the 3′-terminus untranslated region (3′-UTR). We further report the...

Additional file 6 of Folate regulates RNA m5C modification and translation in neural stem cells

Xiguang Xu, Zachary Johnson, Amanda Wang, Rachel L. Padget, James W. Smyth & Hehuang Xie
Additional file 6: Table 5. List of high-confidence m5C sites in mouse NSCs.

Can immune gene silencing via dsRNA feeding promote pathogenic viruses to control the globally invasive Argentine ant?

Antoine Felden, Jana Dobelmann, James W. Baty, Joseph McCormick, John Haywood & Philip J. Lester
Pest control methods that can target pest species with limited environmental impacts are a conservation and economic priority. Species-specific pest control using RNA interference is a challenging but promising avenue in developing the next generation of pest management. We investigate the feasibility of manipulating a biological invader’s immune system using double-stranded RNA (dsRNA) in order to increase susceptibility to naturally occurring pathogens. We used the invasive Argentine ant as a model, targeting the immunity-associated genes...

Additional file 2 of Extracellular matrix profiles determine risk and prognosis of the squamous cell carcinoma subtype of non-small cell lung carcinoma

Amelia L. Parker, Elise Bowman, Adriana Zingone, Brid M. Ryan, Wendy A. Cooper, Maija Kohonen-Corish, Curtis C. Harris & Thomas R. Cox
Additional file 2: Table S1. Differentially Expressed Hallmark Pathways in ECM-High vs ECM-Low Tumors. Table S2. Differentially Expressed MSigDb C2 Pathways in ECM-High vs ECM-Low Tumors. Table S3. Ligand-Receptor Interactions in ECM-High vs ECM-Low Tumors.

Health behaviors are largely not predictive of adverse events following influenza vaccination

Erika Bohn-Goldbaum, Yu Sun Bin, Robert Booy & Kate M Edwards
Identifying health behaviors associated with adverse events following immunization (AEFI) could identify intervention targets for AEFI prevention. University employees receiving an influenza vaccination (n = 1301) completed a series of online surveys for health behaviors including sleep, exercise, dietary intake, and smoking habits, and emotional state (baseline), and for indications of AEFI (three days post-vaccination) and influenza-like illness (ILI) symptoms (fortnightly follow-up for 4 months). 29.9% of participants reported an AEFI and 46.0% reported experiencing...

Additional file 1 of Genome-wide association study uncovers major genetic loci associated with flowering time in response to active accumulated temperature in wild soybean population

Guang Yang, Wei Li, Chao Fan, Miao Liu, Jianxin Liu, Wenwei Liang, Ling Wang, Shufeng Di, Chao Fang, Haiyang Li, Guohua Ding, Yingdong Bi & Yongcai Lai
Additional file 1: Table S1. Prier used in this study. Table S2. List of 392 Glycine soja accessions and acumulated temperature zones. Table S3. 92 SNPs that significantly associated with flowering time in average across the two-year experiment (2020 and 2021). Table S4. The genes conresponding to the genomic regions surrounding ~50Kb of 92 SNPs that signficantly associated with flowering time in average in 2020 and 2021. Table S5. 28 candidate genes related to flowering...

Induction of significant neutralizing antibodies against SARS-CoV-2 by a highly attenuated pangolin coronavirus variant with a 104nt deletion at the 3'-UTR

Shanshan Lu, Shengdong Luo, Chang Liu, Muli Li, Xiaoping An, Mengzhe Li, Jun Hou, Huahao Fan, Panyong Mao, Yigang Tong & Lihua Song
SARS-CoV-2 related coronaviruses (SARS-CoV-2r) from Guangdong and Guangxi pangolins have been implicated in the emergence of SARS-CoV-2 and future pandemics. We previously reported the culture of a SARS-CoV-2r GX_P2V from Guangxi pangolins. Here we report the GX_P2V isolate rapidly adapted to Vero cells by acquiring two genomic mutations: an alanine to valine substitution in the nucleoprotein and a 104-nucleotide deletion in the hypervariable region (HVR) of the 3′-terminus untranslated region (3′-UTR). We further report the...

Toxin cues affect cannibalism responses of cane toad tadpoles

Michael Crossland, Richard Shine & Jayna DeVore
In many species cannibalism is uncommon and involves non-selective consumption of conspecifics as well as heterospecifics. However, within their invasive Australian range cane toad larvae (Rhinella marina) specifically target and voraciously consume the eggs and hatchlings of conspecifics, often extirpating entire clutches. In contrast, toad larvae rarely consume the eggs and hatchlings of native frogs. Here, we use laboratory studies to demonstrate that this selective consumption is triggered by species-specific chemical cues: maternally-invested bufadienolide toxins...

Registration Year

  • 2022
    96

Resource Types

  • Dataset
    96

Affiliations

  • The University of Sydney
    58
  • University of Sydney
    38
  • Fudan University
    22
  • Chinese Academy of Medical Sciences & Peking Union Medical College
    22
  • UNSW Sydney
    21
  • Sichuan University
    20
  • Shanghai Jiao Tong University
    19
  • Shandong University
    14
  • Chinese PLA General Hospital
    14
  • Zhejiang University
    13