6 Works

Data from: Ethanol abolishes vigilance-dependent astroglia network activation in mice by inhibiting norepinephrine release

Martin Paukert, Liang Ye, Murat Orynbayev, Xiangyu Zhu, Eunice Lim, Ram Dereddi, Amit Agarwal, Dwight Bergles & Manzoor Bhat
This collection of data sets was obtained during a study of the effect of acute ethanol intoxication on vigilance-dependent astroglia network activation in mice. The main findings have been that ethanol inhibits astroglia activation by inhibiting vigilance-dependent norepinephrine release. This leads to a failure of activation of alpha1A-adrenergic receptors on astroglia. Further, this study has revealed that ethanol inhibition of cerebellar Bergmann glia Ca2+ activation does not account for ataxic motor behavior, but may rather...

Survey of Core Facilities Raw Data

Isabelle Kos-Braun, Bjoern Gerlach & Claudia Pitzer
Recently, it has become evident that academic research faces issues with the reproducibility of research data. As Core Facilities (CFs) have a central position in the research infrastructure they are able to promote and disseminate good research standards through their users. To identify the most important factors for research quality, we polled 253 CFs across Europe about their practices and analysed in detail the interaction process between CFs and their users, from the first contact...

Exploring whole-genome duplicate gene retention with complex genetic interaction analysis

Elena Kuzmin, Benjamin VanderSluis, Alex N. Nguyen Ba, Wen Wang, Elizabeth N. Koch, Matej Usaj, Anton Khmelinskii, Mojca Mattiazzi Usaj, Jolanda Van Leeuwen, Oren Kraus, Amy Tresenrider, Michael Pryszlak, Ming-Che Hu, Brenda Varriano, Michael Costanzo, Michael Knop, Alan Moses, Chad L. Myers, Brenda J. Andrews & Charles Boone
Whole-genome duplication has played a central role in genome evolution of many organisms, including the human genome. Most duplicated genes are eliminated and factors that influence the retention of persisting duplicates remain poorly understood. Here, we describe a systematic complex genetic interaction analysis with yeast paralogs derived from the whole-genome duplication event. Mapping digenic interactions for a deletion mutant of each paralog and trigenic interactions for the double mutant provides insight into their roles and...

A scalable realization of local U(1) gauge invariance in cold atomic mixtures

Fred Jendrzejewski, Markus K. Oberthaler, Alexander Mil, Torsten V. Zache, Apoorva Hedge, Andy Xia, Rohit P. Bhatt, Philipp Hauke & Jürgen Berges
In the fundamental laws of physics, gauge fields mediate the interaction between charged particles. An example is quantum electrodynamics -- the theory of electrons interacting with the electromagnetic field -- based on U(1) gauge symmetry. Solving such gauge theories is in general a hard problem for classical computational techniques. While quantum computers suggest a way forward, it is difficult to build large-scale digital quantum devices required for complex simulations. Here, we propose a fully scalable...

A little damping goes a long way: code and data

Steve Heim, Matthew Millard, Charlotte Le Mouel & Alexander Badri-Spröwitz
It is currently unclear if damping plays a functional role in legged locomotion, and simple models often do not include damping terms. We present a new model with a damping term that is isolated from other parameters: that is, the damping term can be adjusted without retuning other model parameters for nominal motion. We systematically compare how increased damping affects stability in the face of unexpected ground-height perturbations. Unlike most studies, we focus on task-level...

European soil seed bank communities across a climate and land-cover gradient

Jan Plue, Hans Van Calster, Inger Auestad, Sofia Basto, Reneé M. Bekker, Hans Henrik Bruun, Richard Chevalier, Guillaume Decocq, Ulf Grandin, Martin Hermy, Hans Jacquemyn, Anna Jakobsson, Rein Kalamees, Rob H. Marrs, Bryndis Marteinsdóttir, Per Milberg, Robin J. Pakeman, Gareth Phoenix, Ken Thompson, Vigdis Vandvik, Markus Wagner, Sara A.O. Cousins, Ove Eriksson, Jamshid Ghorbani, Małgorzata Jankowska-Błaszczuk … & Alistair G. Auffret
This is the data set used for the publication Buffering effects of soil seed banks on plant community composition in response to land use and climate, published in the journal Global Ecology and Biogeography. Aim. Climate and land use are key determinants of biodiversity, with past and ongoing changes posing serious threats to global ecosystems. Unlike most other organism groups, plant species can possess dormant life-history stages such as soil seed banks, which may help...

Registration Year

  • 2020

Resource Types

  • Dataset


  • Heidelberg University
  • National Research Institute for Agriculture, Food and Environment
  • Research Institute for Nature and Forest
  • Jan Kochanowski University
  • University of Münster
  • Centre for Ecology and Hydrology
  • Johns Hopkins University
  • University of Groningen
  • University of Minnesota
  • University of California, Berkeley