19 Works

Data from: Evolution of flexible biting in hyperdiverse parasitoid wasps

Thomas Van De Kamp, István Mikó, Arnold H. Staniczek, Benjamin Eggs, Daria Bajerlein, Tomáš Faragó, Lea Hagelstein, Elias Hamann, Rebecca Spiecker, Tilo Baumbach, Petr Janšta & Lars Krogmann
One key event in insect evolution was the development of mandibles with two joints, which allowed powerful biting, but restricted their movement to a single degree of freedom. These mandibles define the Dicondylia, which constitute over 99 percent of all extant insect species. It was common doctrine that the dicondylic articulation of chewing mandibles remained unaltered for more than 400 million years. We report highly modified mandibles overcoming the restrictions of a single degree of...

High plasticity in marmoset monkey vocal development from infancy to adulthood

Steffen Hage, Yasemin Gultekin, Kurt Hammerschmidt & David Hildebrand
The vocal behavior of human infants undergoes dramatic changes across their first year, while becoming increasingly speech-like. Surprisingly, vocal development in nonhuman primates has been assumed to be largely predetermined and completed within the first postnatal months. Contradicting this assumption, we found a dichotomy between the development of call features and vocal sequences in marmoset monkeys suggestive of a role for experience. While changes in call features were related to physical maturation, sequences of and...

Synchronous activity patterns in the dentate gyrus during immobility

Martin Pofahl, Negar Nikbakht, André Haubrich, Theresa Nguyen, Nicola Masala, Fabian Distler, Oliver Braganza, Jakob Macke, Kurtulus Golcuk, Laura Ewell & Heinz Beck
The hippocampal dentate gyrus is an important relay conveying sensory information from the entorhinal cortex to the hippocampus proper. During exploration, the dentate gyrus has been proposed to act as a pattern separator. However, the dentate gyrus also shows structured activity during immobility and sleep. The properties of these activity patterns at cellular resolution, and their role in hippocampal-dependent memory processes have remained unclear. Using dual-color in-vivo two-photon Ca2+ imaging, we show that in immobile...

Weak coordination between leaf drought tolerance and proxy traits in herbaceous plants

Maria Májeková, Tomáš Hájek, Agnes J. Albert, Francesco De Bello, Jiří Doležal, Lars Götzenberger, Stepan Janeček, Jan Lepš, Pierre Liancourt & Ondrej Mudrák
Increased drought is predicted to have a major impact on plant performance under environmental change. Yet leaf hydraulic traits directly related to drought tolerance, such as leaf turgor loss point (πtlp), are underrepresented in trait-based studies and have been largely overlooked within the main frameworks evaluating trait–trait coordination and trade-offs: the leaf economics spectrum and the global spectrum of plant form and function. Using 122 herbaceous species from the Central European temperate grasslands, we investigated...

Transcriptional response of mushrooms to artificial sun exposure

Franz-Sebastian Krah, Jaqueline Hess, Florian Hennicke, Ritwika Kar & Claus Bässler
Climate change causes increased tree mortality leading to canopy loss and thus sun-exposed forest floors. Sun exposure creates extreme temperatures and radiation, with potentially more drastic effects on forest organisms than the current increase in mean temperature. Such conditions might potentially negatively affect the maturation of mushrooms of forest fungi. A failure of reaching maturation would mean no sexual spore release and, thus, entail a loss of genetic diversity. However, we currently have a limited...

Supplementary data for article: Central insulin modulates dopamine signaling in the human striatum

Stephanie Kullmann
Objective: Activity in the dopaminergic pathways of the brain is highly sensitive to body weight and metabolic states. Animal studies show that dopamine neurons are important targets for the metabolic hormone insulin with abolished effects in the insulin resistant state, leading to increases in body weight and food intake. In humans, the influence of central acting insulin on dopamine and effects of their interplay are still elusive. Research Design and Methods: We investigated whether central...

Distinct synaptic transfer functions in same-type photoreceptors

Cornelius Schröder, Takeshi Yoshimatsu, Jonathan Oesterle, Philipp Berens & Tom Baden
Many sensory systems use ribbon-type synapses to transmit their signals to downstream circuits. The properties of this synaptic transfer fundamentally dictate which aspects in the original stimulus will be accentuated or suppressed, thereby partially defining the detection limits of the circuit. Accordingly, sensory neurons have evolved a wide variety of ribbon geometries and vesicle pool properties to best support their diverse functional requirements. However, the need for diverse synaptic functions does not only arise across...

Evaluating grazing response strategies in winter annuals: a multi-trait approach

Susanne Kurze, Mark C. Bilton, Leonor Álvarez-Cansino, Sara Bangerter, Rüdiger Prasse, Katja Tielbörger & Bettina M. J. Engelbrecht
Plants minimize fitness losses through grazing by three fundamental strategies: tolerance, avoidance and escape. Annual species have been traditionally assumed to escape grazing through their short life cycle and seed dormancy, however, their grazing response strategies remain almost unexplored. How traits and their coordination affect species’ grazing responses, and whether the generalized grazing model, which posits convergent filtering by grazing and drought, is applicable to this ecologically and economically important species group thus remain unclear....

The emergence of ecotypes in a parasitoid wasp: a case of incipient sympatric speciation in Hymenoptera?

Pawel Malec, Justus Weber, Marc Fiebig, Denise Meinert, Carolin Rein, Ronja Reinisch, Maik Henrich, Viktoria Polyvas, Marie Pollmann, Lea Von Berg, Christian König, Johannes L.M. Steidle & Robin Böhmer
Background To understand which reproductive barriers initiate speciation is a major question in evolutionary research. Despite their high species numbers and specific biology, there are only few studies on speciation in Hymenoptera. This study aims to identify very early reproductive barriers in a local, sympatric population of Nasonia vitripennis (Walker 1836), a hymenopterous parasitoid of fly pupae. We studied ecological barriers, sexual barriers, and the reduction in F1-female offspring as a postmating barrier, as well...

Supplementary tables for Low-density lipoprotein cholesterol is associated with insulin secretion

Corinna Dannecker, Robert Wagner, Andreas Peter, Julia Hummel, Andreas Vosseler, Hans-Ulrich Häring, Andreas Fritsche, Andreas L. Birkenfeld, Norbert Stefan & Martin Heni
Objective: Pharmacological lowering of LDL cholesterol potently reduces cardiovascular risk while concurrently increasing type 2 diabetes risk. The aim of this study was to investigate the relationship between LDL cholesterol concentrations and insulin secretion and glucagon levels. Methods: 3,039 subjects without cholesterol lowering therapy, but with increased risk for diabetes, underwent routine blood tests and a 5-point oral glucose tolerance test (OGTT). Glucagon concentrations, insulin secretion and insulin clearance indices were derived from the OGTT....

Two-photon calcium recordings of cones

Takeshi Yoshimatsu, Philipp Bartel, Cornelius Schröder, Filip Janiak, Francois St-Pierre, Philipp Berens & Tom Baden
For colour vision, retinal circuits separate information about intensity and wavelength. This requires circuit-level comparison of at least two spectrally distinct photoreceptors. However, many vertebrates use all four ‘ancestral’ photoreceptors (‘red’, ‘green’, ‘blue’, ‘UV’), and in those cases the nature and implementation of this computation remains poorly understood. Here, we establish the complete circuit architecture of outer retinal circuits underlying colour processing in the tetrachromatic larval zebrafish, which involves all four ancestral cone types and...

Data from: Middle Bronze Age land use practices in the north-western Alpine foreland – A multi-proxy study of colluvial deposits, archaeological features and peat bogs

Sascha Scherer, Benjamin Höpfer, Katleen Deckers, Elske Fischer, Markus Fuchs, Ellen Kandeler, Eva Lehndorff, Johanna Lomax, Sven Marhan, Elena Marinova, Julia Meister, Christian Poll, Humay Rahimova, Manfred Rösch, Kristen Wroth, Julia Zastrow, Thomas Knopf, Thomas Scholten & Peter Kühn
This paper aims to reconstruct Middle Bronze Age (MBA) land use practices in the north-western Alpine foreland (SW Germany, Hegau). We used a multi-proxy approach including the biogeochemical proxies from colluvial deposits in the surrounding of the well-documented settlement site of Anselfingen and offsite pollen data from two peat bogs. This approach allowed in-depth insights into the MBA subsistence economy and shows that the MBA in the north-western Alpine foreland was a period of establishing...

Negative impact of roadside mowing on arthropod fauna and its reduction with arthropod-friendly mowing technique

Johannes Steidle, Thomas Kimmich, Michael Csader & Oliver Betz
This dataset contains data from the paper: “Steidle, J. L.M., Kimmich, T., Csader, M. Betz, O. 2021. Negative impact of roadside mowing on arthropod fauna and its reduction with “arthropod-friendly” mowing technique. Journal of Applied Entomology.” The study investigates the impact of a conventional mowing head ("MK1200") and a supposedly "insects-friendly" mowing head ("Eco 1200") during roadside mowing on the arthropod fauna. Mowing with a conventional mowing head caused considerable losses in arthropods, ranging from...

Bat phylogenetic responses to regenerating Amazonian forests

Fábio Z. Farneda, Ricardo Rocha, Sabhrina Gita Aninta, Adrià López-Baucells, Erica M. Sampaio, Jorge M. Palmeirim, Paulo E. D. Bobrowiec, Cristian S. Dambros & Christoph F. J. Meyer
1. Throughout the tropics, regenerating secondary forests occupy vast areas previously cleared for agriculture and cattle ranching. However, despite the importance of regenerating forests in mitigating the pervasive negative consequences of forest loss and fragmentation on forest-associated biodiversity, longitudinal studies on species’ phylogenetic responses to matrix regeneration are rare. 2. We surveyed bats in continuous primary forest, primary forest fragments and in the regenerating secondary forest matrix of a whole-ecosystem Amazonian fragmentation experiment, ~15 and...

Efficacy and safety of Chinese patent medicine (Kang-ai injection) as an adjuvant in the treatment of patients with hepatocellular carcinoma: a meta-analysis

Chuihua Sun, Fang Dong, Ting Xiao & Wenni Gao
Kang-ai injection (KAI) is an authorized herbal medicine used in cancer treatment. However, its clinical efficacy in hepatocellular carcinoma (HCC) has not been investigated thoroughly. To systematically evaluate the efficacy and safety of KAI in patients with HCC. The Web of Science, PubMed, Cochrane Library, EMBASE, CBM, CNKI, VIP and Wanfang databases were systematically searched (date range: inception to December 2020) using the key terms ‘Kang-ai injection’ and ‘hepatocellular carcinoma’. The current analysis included controlled...

Biomechanics of the human thumb and the evolution of dexterity

Fotios Alexandros Karakostis, Daniel Haeufle, Ioanna Anastopoulou, Konstantinos Moraitis, Gerhard Hotz, Vangelis Tourloukis & Katerina Harvati
Systematic tool production and use is one of humanity’s defining characteristics, possibly originating as early as >3 million years ago.​1–3​ Although heightened manual dexterity is considered to be intrinsically intertwined with tool use and manufacture, and critical for human evolution, its role in the emergence of early culture remains unclear. Most previous research on this question exclusively relied on direct morphological comparisons between early hominin and modern human skeletal elements, assuming that the degree of...

Supplemental Data to: Mediterranean Diet, Alzheimer Disease Biomarkers, and Brain Atrophy in Old Age

Tommaso Ballarini, Debora Melo Van Lent, Julia Brunner, Alina Schröder, Steffen Wolfsgruber, Slawek Altenstein, Frederic Brosseron, Katharina Buerger, Peter Dechent, Laura Dobisch, Emrah Düzel, Birgit Ertl-Wagner, Klaus Fliessbach, Silka Dawn Freiesleben, Ingo Frommann, Wenzel Glanz, Dietmar Hauser, John Dylan Haynes, Michael T. Heneka, Daniel Janowitz, Ingo Kilimann, Christoph Laske, Franziska Maier, Coraline Danielle Metzger, Matthias H. Munk … & Michael Wagner
Objective: To determine whether following a Mediterranean-like diet (MeDi) relates to cognitive functions and in vivo biomarkers for Alzheimer disease (AD), we analyzed cross-sectional data from the German DZNE-Longitudinal Cognitive Impairment and Dementia Study. Method: The sample (n = 512, mean age 69.5 ± 5.9 years) included 169 cognitively normal participants and individuals at higher AD risk (53 with relatives with AD, 209 with subjective cognitive decline, and 81 with mild cognitive impairment). We defined...

Optimising flower fields as an effective farmland eco-scheme also during non-breeding

Mirjam R. Rieger, Sarah Mailänder, Lea Stier, Matteo Santon, Julia Staggenborg & Nils Anthes
1. The Common Agricultural Policy (CAP) of the European Union implements several farmland eco-schemes, but most are considered ineffective in halting the population declines of farmland birds. Sown flower fields are among the few eco-scheme types that rate as clearly beneficial. Yet, current CAP regulations lack minimum criteria for flower fields to qualify as eco-scheme, and thus only partially exploit their potential biodiversity benefits. 2. Earlier research on the attraction of farmland birds to different...

Efficacy and safety of Chinese patent medicine (Kang-ai injection) as an adjuvant in the treatment of patients with hepatocellular carcinoma: a meta-analysis

Chuihua Sun, Fang Dong, Ting Xiao & Wenni Gao
Kang-ai injection (KAI) is an authorized herbal medicine used in cancer treatment. However, its clinical efficacy in hepatocellular carcinoma (HCC) has not been investigated thoroughly. To systematically evaluate the efficacy and safety of KAI in patients with HCC. The Web of Science, PubMed, Cochrane Library, EMBASE, CBM, CNKI, VIP and Wanfang databases were systematically searched (date range: inception to December 2020) using the key terms ‘Kang-ai injection’ and ‘hepatocellular carcinoma’. The current analysis included controlled...

Registration Year

  • 2021
    19

Resource Types

  • Dataset
    19

Affiliations

  • University of Tübingen
    19
  • University of Hohenheim
    3
  • University of Sussex
    2
  • Huazhong University of Science and Technology
    2
  • Capital Medical University
    2
  • Southern Medical University
    2
  • University of Bayreuth
    2
  • Charles University
    2
  • Institute of Hematology & Blood Diseases Hospital
    2
  • Shanghai Children's Hospital
    2