8 Works

Transmission experiments support clade-level differences in the transmission and pathogenicity of Cambodian influenza A/H5N1 viruses

Paul F. Horwood, Thomas Fabrizio, Srey Viseth Horm, Artem Metlin, Sopheaktra Ros, Songha Tok, Trushar Jeevan, Patrick Seiler, Phalla Y, Sareth Rith, Annika Suttie, Philippe Buchy, Erik A. Karlsson, Richard Webby & Philippe Dussart
Influenza A/H5N1 has circulated in Asia since 2003 and is now enzootic in many countries in that region. In Cambodia, the virus has circulated since 2004 and has intermittently infected humans. During this period, we have noted differences in the rate of infections in humans, potentially associated with the circulation of different viral clades. In particular, a reassortant clade 1.1.2 virus emerged in early 2013 and was associated with a dramatic increase in infections of...

Data from: Chromosome inversions and ecological plasticity in the main African malaria mosquitoes

Diego Ayala, Pelayo Acevedo, Marco Pombi, Ibrahima Dia, Daniela Boccolini, Carlo Costantini, Frederic Simard & Didier Fontenille
Chromosome inversions have fascinated the scientific community, mainly because of their role in the rapid adaption of different taxa to changing environments. However, the ecological traits linked to chromosome inversions have been poorly studied. Here, we investigated the roles played by 23 chromosome inversions in the adaptation of the four major African malaria mosquitoes to local environments in Africa. We studied their distribution patterns by using spatially explicit modeling and characterized the ecogeographical determinants of...

Data from: Dissecting functional components of reproductive isolation among closely related sympatric species of the Anopheles gambiae complex

Marco Pombi, Pierre Kengne, Geoffrey Gimonneau, Billy Tene-Fossog, Diego Ayala, Colince Kamdem, Federica Santalomazza, Wamdaogo Moussa Guelbeogo, N'Falé Sagnon, Vincenzo Petrarca, Didier Fontenille, Nora J. Besansky, Christophe Antonio-Nkondjio, Roch K. Dabire, Alessandra Della Torre, Frederic Simard & Carlo Costantini
Explaining how and why reproductive isolation evolves and determining which forms of reproductive isolation have the largest impact on the process of population divergence are major goals in the study of speciation. By studying recent adaptive radiations in incompletely isolated taxa, it is possible to identify barriers involved at early divergence before other confounding barriers emerge after speciation is complete. Sibling species of the Anopheles gambiae complex offer opportunities to provide insights into speciation mechanisms....

Transmission experiments support clade-level differences in the transmission and pathogenicity of Cambodian influenza A/H5N1 viruses

Paul F. Horwood, Thomas Fabrizio, Srey Viseth Horm, Artem Metlin, Sopheaktra Ros, Songha Tok, Trushar Jeevan, Patrick Seiler, Phalla Y, Sareth Rith, Annika Suttie, Philippe Buchy, Erik A. Karlsson, Richard Webby & Philippe Dussart
Influenza A/H5N1 has circulated in Asia since 2003 and is now enzootic in many countries in that region. In Cambodia, the virus has circulated since 2004 and has intermittently infected humans. During this period, we have noted differences in the rate of infections in humans, potentially associated with the circulation of different viral clades. In particular, a reassortant clade 1.1.2 virus emerged in early 2013 and was associated with a dramatic increase in infections of...

Genomic shifts, phenotypic clines and fitness costs associated with cold-tolerance in the Asian tiger mosquito

Stéphanie Sherpa, Jordan Tutagata, Thierry Gaude, Frédéric Laporte, Shinji Kasai, Intan Ishak, Xiang Guo, Jiyeong Shin, Sébastien Boyer, Sébastien Marcombe, Theeraphap Chareonviriyaphap, Jean-Philippe David, Xiao-Guang Chen, Xiaohong Zhou & Laurence Després
Climatic variation is a key driver of genetic differentiation and phenotypic traits evolution, and local adaptation to temperature is expected in widespread species. We investigated phenotypic and genomic changes in the native range of the Asian tiger mosquito, Aedes albopictus. We first refine the phylogeographic structure based on genome-wide regions (1,901 double-digest restriction-site associated DNA single nucleotide polymophisms [ddRAD SNPs]) from 41 populations. We then explore the patterns of cold adaptation using phenotypic traits measured...

Data from: Plasmodium vivax diversity and population structure across four continents

Cristian Koepfli, Priscila T. Rodrigues, Tiago Antao, Pamela Orjuela-Sánchez, Peter Van Den Eede, Dionicia Gamboa, Nguyen Van Hong, Jorge Bendezu, Annette Erhart, Céline Barnadas, Arsène Ratsimbasoa, Didier Menard, Carlo Severini, Michela Menegon, Baki Y. M. Nour, Nadira Karunaweera, Ivo Mueller, Marcelo U. Ferreira, Ingrid Felger & Bakri Y. M. Nour
Plasmodium vivax is the geographically most widespread human malaria parasite. To analyze patterns of microsatellite diversity and population structure across countries of different transmission intensity, genotyping data from 11 microsatellite markers was either generated or compiled from 841 isolates from four continents collected in 1999–2008. Diversity was highest in South-East Asia (mean allelic richness 10.0–12.8), intermediate in the South Pacific (8.1–9.9) Madagascar and Sudan (7.9–8.4), and lowest in South America and Central Asia (5.5–7.2). A...

Data from: Evidence of human infection by a new mammarenavirus endemic to Southeastern Asia.

Kim R. Blasdell, Veasna Duong, Marc Eloit, Fabrice Chretien, Sowath Ly, Vibol Hul, Vincent Deubel, Serge Morand & Philippe Buchy
Southeastern Asia is a recognised hotspot for emerging infectious diseases, many of which have an animal origin. Mammarenavirus infections contribute significantly to the human disease burden in both Africa and the Americas, but little data exists for Asia. To date only two mammarenaviruses, the widely spread lymphocytic choriomeningitis virus and the recently described Wēnzhōu virus have been identified in this region, but the zoonotic impact in Asia remains unknown. Here we report the presence of...

Data from: Challenging the conceptual framework of maintenance hosts for influenza A viruses in wild birds

Alexandre Caron, Julien Cappelle & Nicolas Gaidet
1.The conceptual framework considering Anseriformes and Charadriiformes as the main maintenance hosts for influenza A viruses (IAV) in wild birds has shaped IAV research and surveillance over the last decades. 2.We challenge this framework by reviewing the worldwide surveillance data on non-Anseriformes and non-Charadriiformes (NANC) species, generally considered as playing little role in IAV maintenance, available in literature and online data bases (close to 200 sources). 3.Globally, we found an IAV infection rate of 1.51%...

Registration Year

  • 2022
    1
  • 2020
    2
  • 2017
    2
  • 2016
    2
  • 2015
    1

Resource Types

  • Dataset
    8

Affiliations

  • Institut Pasteur du Cambodge
    8
  • Istituto Superiore di Sanità
    2
  • Institut Pasteur
    2
  • James Cook University
    2
  • National Institute of Infectious Diseases
    1
  • University of Gezira
    1
  • Maladies Infectieuses et Vecteurs : Ecologie, Génétique, Evolution et Contrôle
    1
  • University of Notre Dame
    1
  • Institute for Game and Wildlife Research
    1
  • Walter and Eliza Hall Institute of Medical Research
    1