4 Works

Data from: Pulmonary anatomy in the Nile crocodile and the evolution of unidirectional airflow in Archosauria.

Emma R. Schachner, John R. Hutchinson, C. G. Farmer & CG Farmer
The lungs of birds have long been known to move air in only one direction during both inspiration and expiration through most of the tubular gas-exchanging bronchi (parabronchi). Recently a similar pattern of airflow has been observed in American alligators, a sister taxon to birds. The pattern of flow appears to be due to the arrangement of the primary and secondary bronchi, which, via their branching angles, generate inspiratory and expiratory aerodynamic valves. Both the...

Data from: The Oxytricha trifallax macronuclear genome: a complex eukaryotic genome with 16,000 tiny chromosomes

Estienne C. Swart, John R. Bracht, Vincent Magrini, Patrick Minx, Xiao Chen, Yi Zhou, Jaspreet S. Khurana, Aaron D. Goldman, Mariusz Nowacki, Klaas Schotanus, Seolkyoung Jung, Robert S. Fulton, Amy Ly, Sean McGrath, Kevin Haub, Jessica L. Wiggins, Donna Storton, John C. Matese, Lance Parsons, Wei-Jen Chang, Michael S. Bowen, Nicholas A. Stover, Thomas A. Jones, Sean R. Eddy, Thomas G. Doak … & Laura F. Landweber
The macronuclear genome of the ciliate Oxytricha trifallax displays an extreme and unique eukaryotic genome architecture with extensive genomic variation. During sexual genome development, the expressed, somatic macronuclear genome is whittled down to the genic portion of a small fraction (~5%) of its precursor “silent” germline micronuclear genome by a process of “unscrambling” and fragmentation. The tiny macronuclear “nanochromosomes” typically encode single, protein-coding genes (a small portion, 10%, encode 2–8 genes), have minimal noncoding regions,...

Data from: Transcriptome sequencing and microarray development for the woodrat (Neotoma spp.): custom genetic tools for exploring herbivore ecology

Jael Malenke, Brett Milash, Aaron Miller, Denise Dearing, J. R. Malenke, A. W. Miller & M. D. Dearing
Massively parallel sequencing has enabled the creation of novel, in-depth genetic tools for nonmodel, ecologically important organisms. We present the de novo transcriptome sequencing, analysis and microarray development for a vertebrate herbivore, the woodrat (Neotoma spp.). This genus is of ecological and evolutionary interest, especially with respect to ingestion and hepatic metabolism of potentially toxic plant secondary compounds. We generated a liver transcriptome of the desert woodrat (Neotoma lepida) using the Roche 454 platform. The...

Data from: Unidirectional pulmonary airflow patterns in the savannah monitor lizard

Emma R. Schachner, Robert L. Cieri, James P. Butler & C. G. Farmer
The unidirectional airflow patterns in the lungs of birds have long been considered a unique and specialized trait associated with the oxygen demands of their volant lifestyle, endothermic metabolism and unusual pulmonary architecture; however, the discovery of similar flow patterns in the lungs of crocodilians indicates that this character is likely ancestral for all archosaurs, the group that includes extant birds and crocodilians as well as their extinct relatives, such as pterosaurs and dinosaurs. Unidirectional...

Registration Year

  • 2013

Resource Types

  • Dataset


  • University of Utah
  • Howard Hughes Medical Institute
  • Princeton University
  • Royal Veterinary College
  • University of Bern
  • Harvard Medical School
  • Washington University School of Medicine
  • Bradley University