2 Works

Data from: Plasmodium vivax diversity and population structure across four continents

Cristian Koepfli, Priscila T. Rodrigues, Tiago Antao, Pamela Orjuela-Sánchez, Peter Van Den Eede, Dionicia Gamboa, Nguyen Van Hong, Jorge Bendezu, Annette Erhart, Céline Barnadas, Arsène Ratsimbasoa, Didier Menard, Carlo Severini, Michela Menegon, Baki Y. M. Nour, Nadira Karunaweera, Ivo Mueller, Marcelo U. Ferreira, Ingrid Felger & Bakri Y. M. Nour
Plasmodium vivax is the geographically most widespread human malaria parasite. To analyze patterns of microsatellite diversity and population structure across countries of different transmission intensity, genotyping data from 11 microsatellite markers was either generated or compiled from 841 isolates from four continents collected in 1999–2008. Diversity was highest in South-East Asia (mean allelic richness 10.0–12.8), intermediate in the South Pacific (8.1–9.9) Madagascar and Sudan (7.9–8.4), and lowest in South America and Central Asia (5.5–7.2). A...

Data from: Chronic household air pollution exposure is associated with impaired alveolar macrophage function in Malawian non-smokers

Jamie Rylance, Chikondi Chimpini, Sean Semple, David G. Russell, Malcolm J. Jackson, Robert S. Heyderman & Stephen B. Gordon
Background: Household air pollution in low income countries is an important cause of mortality from respiratory infection. We hypothesised that chronic smoke exposure is detrimental to alveolar macrophage function, causing failure of innate immunity. We report the relationship between macrophage function and prior smoke exposure in healthy Malawians. Methods: Healthy subjects exposed daily to cooking smoke at home volunteered for bronchoalveolar lavage. Alveolar macrophage particulate content was measured as a known correlate of smoke exposure....

Registration Year

  • 2015
    2

Resource Types

  • Dataset
    2

Affiliations

  • Liverpool School of Tropical Medicine
    2
  • University of Gezira
    1
  • University of Aberdeen
    1
  • Walter and Eliza Hall Institute of Medical Research
    1
  • University of Melbourne
    1
  • Istituto Superiore di Sanità
    1
  • University of Colombo
    1
  • University of Basel
    1
  • University of Sao Paulo
    1
  • Swiss Tropical and Public Health Institute
    1