5 Works

Vector bionomics and vectorial capacity as emergent properties of mosquito behaviors and ecology

Sean Wu, Penny Hancock, Arnaud Le Menach, Tanya Russell, Thomas Burkot, , Derek Cummings, Kelly Compton, Daniel Citron, John Marshall, Biyonka Liang, Catherine Moyes, Qian Zhang, David Smith, Samson Kiware, Anne Wilson, Thomas Scott, John Henry, Steven Lindsay, Amit Verma & Hector Sanchez C.
Mosquitoes are important vectors for pathogens that infect humans and other vertebrate animals. Some aspects of adult mosquito behavior and mosquito ecology play an important role in determining the capacity of vector populations to transmit pathogens. Here, we re-examine factors affecting the transmission of pathogens by mosquitoes using a new approach. Unlike most previous models, this framework considers the behavioral states and state transitions of adult mosquitoes through a sequence of activity bouts. We developed...

Anopheles stephensi occurrence data 1985 - 2019

Marianne Sinka, Samuel Pironon, Nicola Massey, Joshua Longbottom, Janet Hemingway, Catherine Moyes & Katherine Willis
In 2012, an unusual outbreak of malaria occurred in Djibouti City followed by increasingly severe annual outbreaks. Investigations revealed the presence of an Asian mosquito species; Anopheles stephensi, which thrives in urban environments. Anopheles stephensi has since been identified in Ethiopia and Sudan. By combining data for An. stephensi across its full range (Asia, Arabian Peninsula, Horn of Africa) with spatial models that identify the species’ preferred habitat, we provide evidence-based maps predicting the possible...

Data from: Low coverage genomic data resolve the population divergence and gene flow history of an Australian rain forest fig wasp

Graham Stone, Lisa Cooper, Lynsey Bunnefeld, Jack Hearn, James Cook & Konrad Lohse
Population divergence and gene flow are key processes in evolution and ecology. Model-based analysis of genome-wide datasets allows discrimination between alternative scenarios for these processes even in non-model taxa. We used two complementary approaches (one based on the blockwise site frequency spectrum (bSFS), the second on the Pairwise Sequentially Markovian Coalescent (PSMC)) to infer the divergence history of a fig wasp, Pleistodontes nigriventris. Pleistodontes nigriventris and its fig tree mutualist Ficus watkinsiana are restricted to...

Anopheles stephensi mosquitoes as vectors of Plasmodium vivax and falciparum, Horn of Africa, 2019

Fitsum G. Tadesse, Temesgen Ashine, Hiwot Teka, Endashaw Esayas, Louisa A. Messenger, Wakweya Chali, Lisette Meerstein-Kessel, Thomas Walker, Sinknesh Wolde Behaksra, Kjerstin Lanke, Roel Heutink, Claire L. Jeffries, Daniel Abebe Mekonnen, Elifaged Hailemeskel, Surafel K. Tebeje, Temesgen Tafesse, Abrham Gashaw, Tizita Tsegaye, Tadele Emiru, Kigozi Simon, Eyuel Asemahegn Bogale, Gedeon Yohannes, Soriya Kedir, Girma Shumie, Senya Asfer Sabir … & Teun Bousema
An. stephensi, an efficient malaria vector in parts of Asia and Africa, was observed in 75.3% of water sources surveyed, and contributed to 80.9% of wild-caught Anopheles mosquitoes in Awash Sebat Kilo, Ethiopia. High susceptibility of these mosquitoes to Plasmodium falciparum and vivax infection presents a challenge for malaria control in the Horn of Africa. This study was conducted in Awash Sebat Kilo, Ethiopia, an area of perennial malaria transmission, from April to September 2019....

Selection and exploitation of prevalent, tandemly repeated genomic targets for improved real-time PCR-based detection of Wuchereria bancrofti and Plasmodium falciparum in mosquitoes

Michael Zulch, Nils Pilotte, Jessica Grant, Corrado Minetti, Lisa Reimer & Steven Williams
Background Optimization of polymerase chain reaction (PCR)-based diagnostics requires the careful selection of molecular targets that are both highly repetitive and pathogen-specific. Advances in both next-generation sequencing (NGS) technologies and bioinformatics-based analysis tools are facilitating this selection process, informing target choices and reducing labor. Once developed, such assays provide disease control and elimination programs with an additional set of tools capable of evaluating and monitoring intervention successes. The importance of such tools is heightened as...

Registration Year

  • 2020
    5

Resource Types

  • Dataset
    5

Affiliations

  • Liverpool School of Tropical Medicine
    5
  • University of Oxford
    2
  • London School of Hygiene & Tropical Medicine
    1
  • University of Washington
    1
  • Royal Botanic Gardens
    1
  • U.S. President's Malaria Initiative
    1
  • Clinton Health Access Initiative
    1
  • University of California, Berkeley
    1
  • World Health Organization
    1
  • United States Agency for International Development
    1