10 Works

Macrophage coordination of the interferon lambda immune response

Scott Read
Lambda interferons (IFN-λs) are a major component of the innate immune defense to viruses, bacteria and fungi. In human liver, IFN-λ not only drives antiviral responses, but also promotes inflammation and fibrosis in viral and non-viral diseases. Here we demonstrate that macrophages are primary responders to IFN-λ, uniquely positioned to bridge the gap between IFN-λ producing cells and lymphocyte populations that are not intrinsically responsive to IFN-λ. While CD14+ monocytes do not express the IFN-λ...

Data from: When to cut your losses: dispersal allocation in an asexual filamentous fungus in response to competition

Justin Y. Chan, Stephen P. Bonser, Jeff R. Powell & William K. Cornwell
Fungal communities often form on ephemeral substrates and dispersal is critical for the persistence of fungi among the islands that form these metacommunities. Within each substrate, competition for space and resources is vital for the local persistence of fungi. The capacity to detect and respond by dispersal away from unfavorable conditions may confer higher fitness in fungi. Informed dispersal theory posits that organisms are predicted to detect information about their surroundings which may trigger a...

Data from: Climate warming and plant biomechanical defences: silicon addition contributes to herbivore suppression in a pasture grass

Scott N. Johnson, James M. W. Ryalls, Craig V. M. Barton, Mark G. Tjoelker, Ian J. Wright & Ben D. Moore
1. Plants, notably the Poacae, often accumulate large amounts of silicon (Si) from the soil. Si has multiple functional roles, particularly for alleviating abiotic and biotic stresses (e.g. defence against herbivores). Recent evidence suggests that environmental change, including temperature changes, can diminish Si accumulation which could affect functions such as herbivore defence. 2. Using a field warming experiment, we grew a pasture grass (Phalaris aquatica) that was either supplemented or untreated with Si (+Si and...

Data from: Adaptive variation for growth and resistance to a novel pathogen along climatic gradients in a foundation tree

Collin W. Ahrens, Richard A. Mazanec, Trudy Paap, Katinka X. Ruthrof, Anthea Challis, Giles Hardy, Margaret Byrne, David T. Tissue & Paul D. Rymer
Natural ecosystems are under pressure from increasing abiotic and biotic stressors, including climate change and novel pathogens, which are putting species at risk of local extinction, and altering community structure, composition, and function. Here, we aim to assess adaptive variation in growth and fungal disease resistance within a foundation tree, Corymbia calophylla to determine local adaptation, trait heritability, and genetic constraints in adapting to future environments. Two experimental planting sites were established in regions of...

Data from: Inbreeding alters context‐dependent reproductive effort and immunity in male crickets

Kristin R. Duffield, Kylie J. Hampton, Thomas M. Houslay, John Hunt, Ben M. Sadd & Scott K. Sakaluk
Infection can cause hosts to drastically alter their investment in key life‐history traits of reproduction and defence. Infected individuals are expected to increase investment in defence (e.g., by increasing immune function) and, due to trade‐offs, investment in other traits (e.g., current reproduction) should decrease. However, the terminal investment hypothesis postulates that decreased lifespan due to infection and the associated reduction in the expectation for future offspring will favour increased investment towards current reproduction. Variation in...

Data from: Standing genomic variation within coding and regulatory regions contributes to the adaptive capacity to climate in a foundation tree species

Collin W Ahrens, Margaret Byrne & Paul D Rymer
Global climate is rapidly changing and the ability for tree species to adapt is dependent on standing genomic variation; however the distribution and abundance of functional and adaptive variants are poorly understood in natural systems. We test key hypotheses regarding the genetics of adaptive variation in a foundation tree: genomic variation is associated with climate and genomic variation is more likely to be associated with temperature than precipitation or aridity. To test these hypotheses, we...

Plant functional traits differ in adaptability and are predicted to be differentially affected by climate change

Collin Ahrens, Margaret Andrew, Richard Mazanec, Katinka Ruthrof, Anthea Challis, Giles Hardy, Margaret Byrne, David T. Tissue & Paul Rymer
1. Climate change is testing the resilience of forests worldwide pushing physiological tolerance to climatic extremes. Plant functional traits have been shown to be adapted to climate, and have evolved patterns of trait correlations (similar patterns of distribution) and coordinations (mechanistic trade-off). We predicted that traits would differentiate between populations associated with climatic gradients, suggestive of adaptive variation, and correlated traits would adapt to future climate scenarios in similar ways. 2. We measured genetically determined...

Data from: More than iso/anisohydry: hydroscapes integrate plant water‐use and drought tolerance traits in ten eucalypt species from contrasting climates

Ximeng Li, Chris J. Blackman, Jennifer M. R. Peters, Brendan Choat, Paul D. Rymer, Belinda E. Medlyn & David T. Tissue
The iso/anisohydric continuum describes how plants regulate leaf water potential and is commonly used to classify species drought response strategies. However, drought response strategies comprise more than just this continuum, incorporating a suite of stomatal and hydraulic traits. Using a common garden experiment, we compared and contrasted four metrics commonly used to describe water use strategy during drought in ten eucalyptus species comprising four major ecosystems in eastern Australia. We examined the degree to which...

Data from: Soil organic carbon stability in forests: distinct effects of tree species identity and traits

Gerrit Angst, Kevin E. Mueller, David M. Eissenstat, Susan Trumbore, Katherine H. Freeman, Sarah E. Hobbie, Jon Chorover, Jacek Oleksyn, Peter B. Reich & Carsten W. Mueller
Rising atmospheric CO2 concentrations have increased interest in the potential for forest ecosystems and soils to act as carbon (C) sinks. While soil organic C contents often vary with tree species identity, little is known about if, and how, tree species influence the stability of C in soil. Using a 40‐year‐old common garden experiment with replicated plots of eleven temperate tree species, we investigated relationships between soil organic matter (SOM) stability in mineral soils and...

Multivariate stabilizing sexual selection and the evolution of male and female genital morphology in the red flour beetle

Clarissa House, Philip Tunstall, James Rapkin, Mathilda Janicot Bale, Matthew J. G. Gage, Enrique Del Castillo & John Hunt
Male genitals are highly divergent in animals with internal fertilization. Most studies attempting to explain this diversity have focussed on testing the major hypotheses of genital evolution (the lock-and-key, pleiotropy and sexual selection hypotheses) and quantifying the form of selection targeting male genitals has played an important role in this endeavour. However, we currently know far less about selection targeting female genitals or how male and female genitals interact during mating. Here we use formal...

Registration Year

  • 2019

Resource Types

  • Dataset


  • Western Sydney University
  • Murdoch University
  • Cleveland State University
  • University of Cambridge
  • University of Minnesota
  • Polish Academy of Sciences
  • Institute of Dendrology
  • Macquarie University
  • Department of Agriculture and Food Western Australia
  • Technical University Munich