3 Works

Data from: The effect of sitagliptin on carotid artery atherosclerosis in Type 2 Diabetes: the PROLOGUE randomized controlled trial

Jun-Ichi Oyama, Koichi Node, Atsushi Tanaka, Toyoaki Murohara, Masafumi Kitakaze, Tomoko Ishizu, Yasunori Sato, Haruo Kamiya, Masaharu Ishihara, Koji Maemura, Hirofumi Tomiyama, Yukihito Higashi, Hirotsugu Yamada, Kentaro Yamashita, Yasuko K. Bando, Shinichiro Ueda & Teruo Inoue
Background: Experimental studies have suggested that dipeptidyl peptidase-4 (DPP-4) inhibitors provide cardiovascular protective effects. We performed a randomized study to evaluate the effects of sitagliptin added on to the conventional therapy compared with conventional therapy alone (diet, exercise, and/or drugs, except for incretin-related agents) on the intima-media thickness (IMT) of the carotid artery, a surrogate marker for the evaluation of atherosclerotic cardiovascular disease, in people with type 2 diabetes mellitus (T2DM). Methods and Findings: We...

Data from: Rab6 is required for multiple apical transport pathways but not the basolateral transport pathway in Drosophila photoreceptors

Nozomi Iwanami, Yuri Nakamura, Takunori Satoh, Ziguang Liu & Akiko K. Satoh
Polarized membrane trafficking is essential for the construction and maintenance of multiple plasma membrane domains of cells. Highly polarized Drosophila photoreceptors are an excellent model for studying polarized transport. A single cross-section of Drosophila retina contains many photoreceptors with 3 clearly differentiated plasma membrane domains: a rhabdomere, stalk, and basolateral membrane. Genome-wide high-throughput ethyl methanesulfonate screening followed by precise immunohistochemical analysis identified a mutant with a rare phenotype characterized by a loss of 2 apical...

Data from: Nuclear internal transcribed spacer-1 as a sensitive genetic marker for environmental DNA studies in common carp Cyprinus carpio

Toshifumi Minamoto, Kimiko Uchii, Teruhiko Takahara, Takumi Kitayoshi, Tsuji Satsuki, Hiroki Yamanaka, Hideyuki Doi & Satsuki Tsuji
The recently developed environmental DNA (eDNA) analysis has been used to estimate the distribution of aquatic vertebrates by using mitochondrial DNA (mtDNA) as a genetic marker. However, mtDNA markers have certain drawbacks such as variable copy number and maternal inheritance. In this study, we investigated the potential of using nuclear DNA (ncDNA) as a more reliable genetic marker for eDNA analysis by using common carp (Cyprinus carpio). We measured the copy numbers of cytochrome b...

Registration Year

  • 2016
    3

Resource Types

  • Dataset
    3

Affiliations

  • Hiroshima University
    3
  • Hyogo College of Medicine
    1
  • Tokyo Medical University
    1
  • Animal Science Research Institute
    1
  • Ryukoku University
    1
  • University of Hyogo
    1
  • Chiba University
    1
  • Shimane University
    1
  • Osaka Ohtani University
    1
  • National Cerebral and Cardiovascular Center
    1