6,879 Works

Data from: How can we get close to zero?: the potential contribution of biomedical prevention and the investment framework towards an effective response to HIV

John G. Stover, Timothy B. Hallett, Zunyou Wu, Mitchell Warren, Chaitra Gopalappa, Carel Pretorius, Peter D. Ghys, Julio Montaner, Bernhard Schwartländer & John Stover
Background: In 2011 an Investment Framework was proposed that described how the scale-up of key HIV interventions could dramatically reduce new HIV infections and deaths in low and middle income countries by 2015. This framework included ambitious coverage goals for prevention and treatment services resulting in a reduction of new HIV infections by more than half. However, it also estimated a leveling in the number of new infections at about 1 million annually after 2015....

Data from: Is HIV short-sighted? Insights from a multistrain nested model

Katrina Abigail Lythgoe, Lorenzo Pellis & Christophe Fraser
An important component of pathogen evolution at the population level is evolution within hosts. Unless evolution within hosts is very slow compared to the duration of infection, the composition of pathogen genotypes within a host is likely to change during the course of an infection, thus altering the composition of genotypes available for transmission as infection progresses. We develop a nested modeling approach that allows us to follow the evolution of pathogens at the epidemiological...

Data from: A comparative analysis of the mechanisms underlying speciation on Lord Howe Island

Alexander S. T. Papadopulos, Zuzana Price, Celine Devaux, Helen Hipperson, Carole M. Smadja, Ian Hutton, William J. Baker, Roger K. Butlin & Vincent Savolainen
On Lord Howe Island, speciation is thought to have taken place in situ in a diverse array of distantly related plant taxa (Metrosideros, Howea and Coprosma; Proc. Natl Acad. Sci. USA 108, 2011, 13188). We now investigate whether the speciation processes were driven by divergent natural selection in each genus by examining the extent of ecological and genetic divergence. We present new and extensive, ecological and genetic data for all three genera. Consistent with ecologically...

Organic Esters for detailed NMR Analysis

Henry Rzepa
1H NMR Spectra

Cumyl ethyl malonate

Henry Rzepa
Ethyl malonyl chloride (234mg, 1.56mmole) was added in one go to a stirred solution of cumyl acohol (227mg, 1.67mmole) and N,N-dimethylaniline (164mg, 1.36mmole) in diethyl ether (2ml). The reaction was exothermic and the mixture went cloudy. After stirring at room temperature over the weekend, the supernatant of the reaction was applied to a column of silica gel and the product eluted with hexane : ethyl acetate (5 : 1) as a sweet-smelling, colourless oil (248mg).

Fe(+)C trigonal, quad pinned back, quad

Henry Rzepa
Gaussian Calculation

IDOZOQ, NBO = triple 1-105

Henry Rzepa
Gaussian Calculation

TISQOE Re-O(+)

Henry Rzepa
Gaussian Calculation

TISQOE Re-O(+)

Henry Rzepa
Gaussian Calculation

TISQOE W-O

Henry Rzepa
Gaussian Calculation

TISQOE Os-O(2+)

Henry Rzepa
Gaussian Calculation

MPV 1, b3lyp+GD3BJ/Def2-SVPP, SCRF=THF, reactant t-butyl, , G = -1712.715051

Henry Rzepa
Gaussian Calculation

MPV 1, b3lyp+GD3BJ/Def2-SVPP, SCRF=THF, reactant perfluoro-t-butyl, G = -2605.305170

Henry Rzepa
Gaussian Calculation

MPV 1, b3lyp+GD3BJ/3-21G, SCRF=THF, TS, G = -1548.478051 (epimer, G = -1548.473944, DG = 2.6)

Henry Rzepa
Gaussian Calculation

GAJXOH, Molybdenum

Henry Rzepa
Gaussian Calculation

MPV 2 + t-butyl, b3lyp+GD3BJ/Def2-SVPP, SCRF=THF, TS, G = -1712.698928 DG = 1.39

Henry Rzepa
Gaussian Calculation

MPV 1, b3lyp+GD3BJ/3-21G, SCRF=THF, TS, epimer, G = -1548.473944 IRC

Henry Rzepa
Gaussian Calculation

Two new reality-based suggestions for molecules with a quadruple bond to carbon.

Henry Rzepa
Gaussian 16 calculations

Data from: Changes in liana density over 30 years in a Bornean rain forest supports the escape hypothesis

David Newbery, Cedric Zahnd & Elaine Campbell
In two permanent plots of lowland dipterocarp forest at Danum a liana census in 1988 was repeated in 2018 using the same method. Trees ≥ 30 cm gbh (girth at breast height) were recorded for number of lianas ≥ 2 cm gbh on their stems. The forest was evidently in a late stage of recovery from a large natural disturbance. Over the interval, mean number of lianas per tree decreased by 22 and 34 %...

Me2S-CC dimerisation wB97XD/Def2-TZVPPD SCRF=DCM, (Ci symmetry) reactant

Henry Rzepa
Gaussian Calculation

Me2S-CC 1,1-dimerisation wB97XD/Def2-TZVPPD SCRF=DCM, 2nd phase, 3-7 G = -1108.064236

Henry Rzepa
Gaussian Calculation

MeCl-CC 1,1-Dimerisation Def2-TZVPPD/SCRF=DCM, G = -1152.143950

Henry Rzepa
Gaussian Calculation

Fish species and production in Welsh rivers along a biodiversity gradient (2012 - 2013)

I. Durance, H.B. Feeley, M.C. Pye, C. Gutierrez-Canovas, S.J. Ormerod & G. Woodward
This dataset consists of fish species, fish length and fish weight from samples taken from small and medium catchments across Wales. Samples were collected in the summers and autumns of 2012 and 2013 using electrofishing. All the collected individuals were counted and recorded to represent the fish diversity and abundance of each sampling site and date. The main goal of this survey was to relate fish production with a gradient of aquatic biodiversity associated with...

Data from: Metabarcoding of freshwater invertebrates to detect the effects of a pesticide spill

Carmelo Andujar, Paula Arribas, Clare Gray, Katherine Bruce, Guy Woodward, Douglas W. Yu & Alfried P. Vogler
Biomonitoring underpins the environmental assessment of freshwater ecosystems and guides management and conservation. Current methodology for surveys of (macro)invertebrates uses coarse taxonomic identification where species-level resolution is difficult to obtain. Next-generation sequencing of entire assemblages (metabarcoding) provides a new approach for species detection, but requires further validation. We used metabarcoding of invertebrate assemblages with two fragments of the cox1 "barcode" and partial nuclear ribosomal (SSU) genes, to assess the effects of a pesticide spill in...

Data from: An exploratory study of staff perceptions of shift safety in the critical care unit and routinely available data on workforce, patient and organisational factors

Clare Leon-Villapalos, Stephen J Brett & Mary Wells
Objectives To explore: bedside professional reported (BPR) perceptions of safety in intensive care staff; and the relationships between BPR safety, staffing, patient and work environment characteristics. Design An exploratory study of self-recorded staff perceptions of shift safety and routinely collected data. Setting A large teaching hospital comprising 70 critical care beds. Participants All clinical staff working in adult critical care. Interventions Staff recorded whether their shift felt “safe, unsafe or very unsafe” for 29 consecutive...

Registration Year

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    70
  • 2014
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  • 2013
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  • 2012
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Resource Types

  • Dataset
    6,879

Affiliations

  • Imperial College London
    6,879
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    35
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