1,092 Works

CF3F2I-CC 1,2-dimerisation, Def2-TZVPPD, G = -1822.241919 DG = 11.1

Henry Rzepa
Gaussian 16 (C01) calculation

Prevalence of Batrachochytrium dendrobatidis and Batrachochytrium salamandrivorans in thre Hoang Lien Range, northwest Vietnam

Benjamin Tapley, Phillip Jervis, Luan Nguyen, Christopher Portway, Chung Nguyen, Hao Luong, Daniel Kane, Lola Brookes, Matthew Perkins, Pria Ghosh, Claudia Wierzbicki, Jennifer Shelton, Matthew Fisher & Jodi Rowley
This study aims to investigate the presence of the amphibian chytrid fungi Batrachochytrium dendrobatidis (Bd) and Batrachochytrium salamandrivorans (Bsal) in the Hoang Lien Range, northwest Vietnam as well as any patterns in Bd infection in space, time and host species over a five-year sampling period. This study also aims to investigate the presence of Bsal in the Hoang Lien Range.

DragonDrop: passive dynamics and control strategies of aerial righting in the dragonfly

Sam Fabian, Rui Zhou & Huai-Ti Lin
Dragonflies perform dramatic aerial manoeuvres when hunting prey or chasing rivals but glide leisurely with wings virtually fixed. This makes dragonflies a great system to explore how to minimize the trade-off between manoeuvrability and stability. We challenged the dragonfly by dropping it from selected inverted attitudes and digitised the 6-degrees-of-freedom aerial recovery kinematics via custom motion capture techniques. From these kinematic data we then performed rigid-body inverse dynamics to reconstruct the forces and torques involved...

Data from: The effect of resource limitation on the temperature-dependence of mosquito population fitness

PJ Huxley, KA Murray, S Pawar & LJ Cator
Laboratory-derived temperature dependencies of life history traits are increasingly being used to make mechanistic predictions for how climatic warming will affect vector-borne disease dynamics, partially by affecting abundance dynamics of the vector population. These temperature-trait relationships are typically estimated from juvenile populations reared on optimal resource supply, even though natural populations of vectors are expected to experience variation in resource supply, including intermittent resource limitation. Using laboratory experiments on the mosquito Aedes aegypti, a principal...

Multi-year time shift study of bacteria and phage dynamics in the phyllosphere

Emily Dewald-Wang, Nicole Parr, Katie Tiley, Alina Lee & Britt Koskella
Coevolutionary dynamics shape diversity within and among populations but are difficult to study directly. Time shift experiments, where populations of species A from one point in time are experimentally challenged against populations of species B from past, contemporary, and/or future time points, and vice versa, are a particularly powerful tool to measure coevolution. This approach has been primarily applied to study host-parasite interactions and proven useful in directly measuring coevolutionary change and distinguishing among coevolutionary...

Comparative evaluation of ten lateral flow immunoassays to detect SARS-CoV-2 antibodies

Gala Garrod, Sophie Owen, Kenneth Baillie, Lisa Baldwin, Lottie Brown, Rachel Byrne, Ana Cubas-Atienzar, Luis Cuevas, Alice Fraser, Thomas Fletcher, Lynsey Goodwin, Grant Kay, Konstantina Kontogianni, Jenifer Mason, Peter Openshaw, Stefanie Menzies, Shona Moore, Malcolm Semple, Joseph Taylor, Lance Turtle, Christopher Williams & Emily Adams
Background: Rapid mobilisation from industry and academia following the outbreak of the novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), led to the development and availability of SARS-CoV-2 lateral flow immunoassays (LFAs). High-quality LFAs are urgently needed at the point of care to add to currently available diagnostic tools. In this study, we provide evaluation data for ten LFAs suitable for use at the point of care. Methods: COVID-19 positive patients (N=45), confirmed by...

Data from: A Silurian ophiuroid with soft tissue preservation

Reece Carter, Mark Sutton, Derek Briggs, David Siveter & Derek Siveter
Palaeozoic brittle stars are not equipped with the fused arm ossicles (vertebrae) that facilitate the remarkable mode of walking that characterizes living forms. Here we describe a stem ophiuroid from the Herefordshire Lagerstätte (Silurian, Wenlock Series) which is remarkable in preserving the body cavity uncompacted and long tube feet which lack suckers. We tentatively assign the specimen to Protaster. The morphology of the arms and attitude of the specimen suggest that locomotion was achieved by...

Gene-drive suppression of mosquito populations in large cages as a bridge between lab and field

Andrew Hammond, Paola Pollegioni, Tania Persampieri, Ace North, Roxana Minuz, Alessandro Trusso, Alessandro Bucci, Kyros Kyrou, Ioanna Morianou, Alekos Simoni, Tony Nolan, Ruth Müller & Andrea Crisanti
CRISPR-based gene-drives targeting the gene doublesex in the malaria vector Anopheles gambiae effectively suppressed the reproductive capability of mosquito populations reared in small laboratory cages. To bridge the gap between laboratory and the field, this gene-drive technology must be challenged with vector ecology. Here we report the suppressive activity of the gene-drive in age-structured An. gambiae populations in large indoor cages that permit complex feeding and reproductive behaviours. The gene-drive element spreads rapidly through the...

Evidence shortfalls in the recommendations and guidance underpinning ecological mitigation for infrastructure developments

Sara Bronwen Hunter, Sophus Zu Ermgassen, Harriet Downey, Richard Griffiths & Caroline Howe
1. In the UK and European Union, legal protection of species from the impacts of infrastructure development depends upon a number of ecological mitigation and compensation (EMC) measures to moderate the conflict between development and conservation. However, the scientific evidence supporting their effectiveness has not yet been comprehensively assessed. 2. This study compiled the measures used in practice, identified and explored the guidance that informed them and, using the Conservation Evidence database, evaluated the empirical...

Data from: Achieving a step change in the tuberculosis epidemic through comprehensive community-wide intervention: A model-based analysis

Sourya Shrestha, Emily Kendall, Rebekah Chang, Roy Joseph, Parastu Kasaie, Laura Gillini, Anthony Todd Fojo, Michael Campbell, Nimalan Arinaminpathy & David Dowdy
Background: Global progress towards reducing tuberculosis (TB) incidence and mortality has consistently lagged behind World Health Organization targets leading to a perception that large reductions in TB burden cannot be achieved. However, several recent and historical trials suggest that intervention efforts that are comprehensive and focused can have substantial epidemiological impact. We aimed to quantify the potential epidemiological impact of an intensive but realistic, community-wide campaign utilizing existing tools, and designed to achieve a “step...

Vegetation responses to Soay sheep grazing on St Kilda

Mick Crawley
1. The population of Soay sheep on the island of Hirta in the Outer Hebrides has been the subject of continuous study for more than 35 years. This paper focuses on the botanical aspects of the plant-herbivore interaction, showing how the vegetation affects and is affected by the sheep. 2. Grazing impacts on biomass and spatial structure varied across plant communities, with Holcus/Agrostis grasslands affected most and Wet Heath least, consistent with the hypothesis that...

Data from: Developmental origins of the crocodylian skull table and platyrostral face

Zachary S. Morris, Kent A. Vliet, Arhat Abzhanov & Stephanie E. Pierce
The dorsoventrally flattened skull typifies extant Crocodylia perhaps more than any other anatomical feature and is generally considered an adaptation for semi-aquatic feeding. Although the evolutionary origins have been extensively studied, the developmental origins of craniofacial flattening have yet to be explored. To understand how the skull table and platyrostral snout develop, we quantified embryonic development and post-hatching growth (ontogeny) of the crocodylian skull in lateral view using geometric morphometrics. Our dataset (n=103) includes all...

Data from: Fractal triads efficiently sample ecological diversity and processes across spatial scales

Elizabeth Simpson & William Pearse
The relative influence of ecological assembly processes, such as environmental filtering, competition, and dispersal, vary across spatial scales. Changes in phylogenetic and taxonomic diversity across environments provide insight into these processes, however, it is challenging to assess the effect of spatial scale on these metrics. Here, we outline a nested sampling design that fractally spaces sampling locations to concentrate statistical power across spatial scales in a study area. We test this design in northeast Utah,...

TS2, b3lyp+GD3BJ/Def2-TZVPP G = -1714.704527

Henry Rzepa
Gaussian 16 (C01) calculation

Post Product b3lyp three THF solvents Def2-TZVPP, adamantanylmethanol - ketone removed G = -1209.700176

Henry Rzepa
Gaussian 16 (C01) calculation. Total product free energy -1947.198458

Post Product b3lyp three THF solvents Def2-TZVPP, ketone, G -737.498282

Henry Rzepa
Gaussian 16 (C01) calculation. Total product free energy -1947.198458

PAXLOVID NCI

Henry Rzepa
Gaussian 16 (C01) calculation

Productivity, niche availability, species richness and extinction risk: Untangling relationships using individual-based simulations

Euan Furness, Russell Garwood, Philip Mannion & Mark Sutton
It has been widely hypothesised that the productivity of an ecosystem affects the number of species that it can support. Despite decades of study, the nature, extent, and underlying mechanisms of this relationship are unclear. One suggested mechanism is the “more individuals” hypothesis (MIH). This proposes that productivity controls the number of individuals in the ecosystem, and that more individuals can be divided into a greater number of species before their population size is sufficiently...

MeSH + acetonitrile + H2O

Henry Rzepa
Gaussian 16 (C01) calculation

Biotin sub fragment

Henry Rzepa
Gaussian 16 (C01) calculation

hexane-CFCl3-wb97xd-def2svpp

Alexandre Dumon
Gaussian Calculation

hexane-CFCl3-B3LYP-def2svpp

Alexandre Dumon
Gaussian Calculation

Heptane-CFCl3-B3LYP-augpvdz

Alexandre Dumon
Gaussian Calculation

o-DCB-CFCl3-wb97xd-augpvdz

Alexandre Dumon
Gaussian Calculation

H2O-CFCl3-wb97xd-augpcSseq1

Alexandre Dumon
Gaussian Calculation

Registration Year

  • 2021
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  • Dataset
    1,092

Affiliations

  • Imperial College London
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  • University of Cambridge
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  • Estación Biológica de Doñana
    2
  • Zhejiang University
    2
  • University of Sussex
    2
  • University of Notre Dame
    2
  • University of Georgia
    2