3 Works

Data from: Genetic diversity and population structure of the tsetse fly Glossina fuscipes fuscipes (Diptera: Glossinidae) in Northern Uganda: implications for vector control

Robert Opiro, Norah P. Saarman, Richard Echodu, Elizabeth A. Opiyo, Kirstin Dion, Alexis Halyard, Augustine W. Dunn, Serap Aksoy, Adalgisa Caccone & Philippe Solano
Uganda is the only country where the chronic and acute forms of human African Trypanosomiasis (HAT) or sleeping sickness both occur and are separated by < 100 km in areas north of Lake Kyoga. In Uganda, Glossina fuscipes fuscipes is the main vector of the Trypanosoma parasites responsible for these diseases as well for the animal African Trypanosomiasis (AAT), or Nagana. We used highly polymorphic microsatellite loci and a mitochondrial DNA (mtDNA) marker to provide...

Data from: A spatial genetics approach to inform vector control of tsetse flies (Glossina fuscipes fuscipes) in Northern Uganda

Norah Saarman, Mary Burak, Robert Opiro, Chaz Hyseni, Richard Echodu, Kirstin Dion, Elizabeth A. Opiyo, Augustine W. Dunn, Giuseppe Amatulli, Serap Aksoy & Adalgisa Caccone
Tsetse flies (genus Glossina) are the only vector for the parasitic trypanosomes responsible for sleeping sickness and nagana across sub-Saharan Africa. In Uganda, the tsetse fly Glossina fuscipes fuscipes is responsible for transmission of the parasite in 90% of sleeping sickness cases, and co-occurrence of both forms of human-infective trypanosomes makes vector control a priority. We use population genetic data from 38 samples from northern Uganda in a novel methodological pipeline that integrates genetic data,...

Data from: The population genomics of multiple tsetse fly (Glossina fuscipes fuscipes) admixture zones in Uganda

Norah P. Saarman, Robert Opiro, Chaz Hyseni, Richard Echodu, Elizabeth A. Opiyo, Kirstin Dion, Thomas Johnson, Serap Aksoy & Adalgisa Caccone
Understanding the mechanisms that enforce, maintain, or reverse the process of speciation is an important challenge in evolutionary biology. This study investigates the patterns of divergence and discusses the processes that form and maintain divergent lineages of the tsetse fly Glossina fuscipes fuscipes in Uganda. We sampled 251 flies from 18 sites spanning known genetic lineages and the four admixture zones between them. We apply population genomics, hybrid zone, and approximate Bayesian computation to the...

Registration Year

  • 2018
    3

Resource Types

  • Dataset
    3

Affiliations

  • Yale University
    3
  • Gulu University
    3
  • Boston Children's Hospital
    2
  • University of Mississippi
    2