2 Works

Data from: The role of platelets in mediating a response to human influenza infection

Milka Koupenova, Heather A. Corkrey, Olga Vitseva, Giorgia Manni, Catherine J. Pang, Lauren Clancy, Chen Yao, Jeffrey Rade, Daniel Levy, Jennifer P. Wang, Robert W. Finberg, Evelyn A. Kurt-Jones & Jane E. Freedman
Influenza infection increases the incidence of myocardial infarction but the reason is unknown. Platelets mediate vascular occlusion through thrombotic functions but are also recognized to have immunomodulatory activity. To determine if platelet processes are activated during influenza infection, we collected blood from 18 patients with acute influenza infection. Microscopy reveals activated platelets, many containing viral particles and extracellular- DNA associated with platelets. To understand the mechanism, we isolated human platelets and treated them with influenza...

Transitions in paternal social status predict patterns of offspring growth and metabolic transcription

Joseph W. Cauceglia, Adam C. Nelson, Nimrod D. Rubinstein, Shweta Kukreja, Lynsey N. Sasso, John A. Beaufort, Oliver J. Rando & Wayne K. Potts
Parental effects occur when changes in the parental phenotype or environment cause changes to offspring phenotype. While some parental effects are triggered in response to an environmental cue in a time-locked fashion, other parental effects persist even after the cue has been removed, suggesting multiple timescales of action. For parental effects to serve as reliable signals of current environmental conditions, they should be reversible, such that when the cue changes, offspring phenotypes change in accordance....

Registration Year

  • 2019
    2

Resource Types

  • Dataset
    2

Affiliations

  • University of Massachusetts Medical School
    2
  • Google (United States)
    1
  • University of Perugia
    1
  • National Institutes of Health
    1
  • University of Utah
    1
  • Harvard University
    1