137 Works

Polymorphisms in dipeptidyl peptidase 4 reduce host cell entry of Middle East respiratory syndrome coronavirus

Hannah Kleine-Weber, Simon Schroeder, Nadine Krüger, Alexander Prokscha, Hassan Y. Naim, Marcel A. Müller, Christian Drosten, Stefan Pöhlmann & Markus Hoffmann
Middle East respiratory syndrome (MERS) coronavirus (MERS-CoV) causes a severe respiratory disease in humans. The MERS-CoV spike (S) glycoprotein mediates viral entry into target cells. For this, MERS-CoV S engages the host cell protein dipeptidyl peptidase 4 (DPP4, CD26) and the interface between MERS-CoV S and DPP4 has been resolved on the atomic level. Here, we asked whether naturally-occurring polymorphisms in DPP4, that alter amino acid residues required for MERS-CoV S binding, influence cellular entry...

Survival of antimicrobial peptide resistant Staphylococcus aureus in mealworm beetles (Tenebrio molitor) with manipulated AMPexpression

Jens Rolff & Baydaa El Shazely
Antimicrobial peptides (AMP) are essential immune effectors of multicellular organisms. Bacteria can evolve resistance to AMPs. Surprisingly, when used to challenge the insect Tenebrio molitor, Staphylococcus aureus resistant to an abundant beetle AMP (tenecin 1) and also pleiotropically to phagocytosis did not increase host mortality or bacterial load compared to infections with wild-type S. aureus. A possible explanation is that antimicrobial resistance is costly due to collaterally increased sensitivity of AMP-resistant strains to other immune...

Mobility Transition Model - excerpt from 2018 Decision Theatre scenario data

Andreas Geiges, Steffen Fürst, Gesine Steudle, Sarah Wolf & Carlo Jaeger

Bee diversity in island-like habitats (kettle holes) to assess connectivity in agricultural landscapes - Part 1 of data collection

Sissi Lozada-Gobilard
During June and July of 2017, wild bees were collected using color traps (blue, yellow and white pans) in small water bodies called kettle holes embedded in agricultural landscapes in the north of Germany. After all wild bees were identified to species level, from a subset of samples we measured the Intertegular distance ITD (distance between the wings) as body size and searched for functional traits regarding sociality (solitary, eusocial, parasitic) nesting type (below- or...


Céline COUGOULE, David Pericat, Stephen Adonai Leon-Icaza, Marina Sánchez-Rico, Christiane Mühle, Iulia Zoicas, Fabian Schumacher, Rémi Planès, Raoul MAZARS, Germain Gros, Alexander Carpinteiro, Katrin Anne Becker, Jacques Izopet, Nathalie Strub-Wourgaft, Peter Sjö, Olivier Neyrolles, Burkhard Kleuser, Frédéric Limosin, Erich Gulbins, Johannes Kornhuber, Etienne Meunier & Nicolas Hoertel
Data from manuscript " Antiviral and Anti-Inflammatory Activities of Fluoxetine in a SARS-CoV-2 Infection Mouse Model" by Péricat David et al.

Voter Dynamics on Clustered Networks

Jan-Hendrik Niemann
The dynamical behavior of social systems can be described by agent-based models. One famous and important model for the description of voting behavior is the so-called (extended) voter model where agents decide between various options based on different rules. A key factor is the interaction network, that is what information the agents obtain and how they interact with each other. This data set provides simulation data to analyze the influence of the interaction network. A...

Livestock management promotes bush encroachment in savanna systems by altering plant-herbivore feedback

Franziska Koch, Britta Tietjen, Katja Tielbörger & Korinna Allhoff
This repository contains all code to reproduce the analysis in Koch et al. 2022 "Livestock management promotes bush encroachment in savanna systems by altering plant-herbivore feedback". We use a set of coupled differential equations to describe competition between shrubs and grasses, as well as plant biomass consumption via grazing and browsing. Grazers were assumed to receive a certain level of care from farmers, so that grazer densities emerge dynamically from the combined effect of vegetation...

Impact of new traumatic or stressful life events on pre-existing PTSD in traumatized refugees: results of a longitudinal study

Katrin Schock, Maria Böttche, Rita Rosner, Mechthild Wenk-Ansohn & Christine Knaevelsrud
Background: A significant proportion of trauma survivors experience an additional critical life event in the aftermath. These renewed experiences of traumatic and stressful life events may lead to an increase in trauma-related mental health symptoms. Method: In a longitudinal study, the effects of renewed experiences of a trauma or stressful life event were examined. For this purpose, refugees seeking asylum in Germany were assessed for posttraumatic stress symptoms (PTS), Posttraumatic Stress Diagnostic Scale (PDS), anxiety,...

Data from: Savanna resilience to droughts increases with proportion of browsing wild herbivores and plant functional diversity

Katja Irob
1. Maintaining the resilience and functionality of savannas is key to sustaining the ecosystem services they provide. This maintenance is largely dependent on the resilience of savannas to stressors, such as prolonged droughts. The resilience to drought is largely determined by the interaction of herbivores and the functional composition of vegetation. So far, our understanding and ability to predict the response of savannas to drought under different types of rangeland use and as a function...

Data from: Can fractal dimensions objectivize gastropod shell morphometrics? A case study from Lake Lugu (SW China)

Robert Wiese, Kyle Harrington, Kai Hartmann, Manja Hethke, Thomas Von Rintelen, Hucai Zhang, Le-Jia Zhang & Frank Riedel
Morphometrics are fundamental for statistical analyses of fossils, particularly because soft parts or DNA are rarely preserved and thus hard parts such as shells are commonly the only source of information. Geometric morphometrics i.e. landmark analysis has been successfully established but exhibits a couple of shortcomings. On the one hand landmarking is rather subjective and on the other hand the application at the level of micro-sculpture is difficult. With the aid of high-resolution 3D scanning...

Projective cover of ground vegetation types at 58 sites in Central and Eastern Yakutia, in Summer 2021 (RU-Land_2021_Yakutia)

Laura Schild, Stefan Kruse, Birgit Heim, Amelie Stieg, Barbara von Hippel, Josias Gloy, Viktor Smirnikov, Nils Töpfer, Elena I Troeva, Luidmila A Pestryakova & Ulrike Herzschuh
Vegetation surveys were carried out in four different study areas in the Sakha Republic, Russia: in the mountainous region of the Verkhoyansk Range within the Oymyakonsky and Tomponsky District (Event EN21-201 - EN21-219), and in three lowland regions of Central Yakutia within the Churapchinsky, Tattinsky and the Megino-Kangalassky District (Event EN21220 - EN21264). The study area is located within the boreal forest biome that is underlain by permafrost soils. The aim was to record the...

First Artificial Receptor for Caffeine—A New Concept for the Complexation of Alkylated Oxopurines

Siegfried R. Waldvogel, Roland Fröhlich & Christoph A. Schalley

Registration Year

  • 2023
  • 2022
  • 2021
  • 2020
  • 2019
  • 2018
  • 2017
  • 2016
  • 2015
  • 2014

Resource Types

  • Dataset


  • Freie Universität Berlin
  • Leibniz Institute of Freshwater Ecology and Inland Fisheries
  • Berlin Brandenburg Institute of Advanced Biodiversity Research
  • Leibniz Institute for Zoo and Wildlife Research
  • University of Göttingen
  • Fudan University
  • German Center for Integrative Biodiversity Research
  • North-Eastern Federal University
  • University of Potsdam
  • Institut für Biologie, Freie Universität Berlin