40 Works

Data from: Experimentally reduced insulin/IGF-1 signalling in adulthood extends lifespan of parents and improves Darwinian fitness of their offspring

Martin I. Lind, Sanjana Ravindran, Zuzana Sekajova, Hanne Carlsson, Andrea Hinas & Alexei A. Maklakov
Classical theory maintains that ageing evolves via energy trade-offs between reproduction and survival leading to accumulation of unrepaired cellular damage with age. In contrast, the emerging new theory postulates that ageing evolves because of deleterious late-life hyper-function of reproduction-promoting genes leading to excessive biosynthesis in late-life. The hyper-function theory uniquely predicts that optimizing nutrient-sensing molecular signalling in adulthood can simultaneously postpone ageing and increase Darwinian fitness. Here we show that reducing evolutionarily conserved insulin/IGF-1 nutrient-sensing...

Data from: Postglacial colonization routes coincide with a life history breakpoint along a latitudinal gradient

Emilien Luquet, Patrik Rödin-Mörch, Maria Cortazar-Chinarro, Yvonne Meyer-Lucht, Jacob Höglund & Anssi Laurila
While adaptive divergence along environmental gradients has repeatedly been demonstrated, the role of postglacial colonization routes in determining phenotypic variation along gradients has received little attention. Here we used a hierarchical QST-FST approach to separate the roles of adaptive and neutral processes in shaping phenotypic variation in moor frog (Rana arvalis) larval life-histories along a 1700 km latitudinal gradient across northern Europe. This species has colonized Scandinavia via two routes with a contact zone in...

Data from: Asymmetrical habitat coupling of an aquatic predator – the importance of individual specialisation

Maria H.K. Marklund, Richard Svanback, Leanne Faulks, Martin F. Breed, Kristin Scharnweber, Yinghua Zha & Peter Eklöv
Predators should stabilise food webs because they can move between spatially separate habitats. However, predators adapted to forage on local resources may have a reduced ability to couple habitats. Here we show clear asymmetry in the ability to couple habitats by Eurasian perch – a common polymorphic predator in European lakes. We sampled perch from two spatially separate habitats – pelagic and littoral zones – in Lake Erken, Sweden. Littoral perch showed stronger individual specialisation,...

Data from: The effects of male social environment on sperm phenotype and genome integrity

Willian T.A.F. Silva, Paula Saez-Espinosa, Stephanie Torijo Boix, Alejandro Romero, Caroline Devaux, Mathilde Durieux, Maria Jose Gomez Torres & Simone Immler
Sperm function and quality are primary determinants of male reproductive performance and hence fitness. The presence of rival males has been shown to affect ejaculate and sperm traits in a wide range of taxa. However, male physiological conditions may not only affect sperm phenotypic traits but also their genetic and epigenetic signatures, affecting the fitness of the resulting offspring. We investigated the effects of male-male competition on sperm quality using TUNEL assays and geometric morphometrics...

Data from: Parental genetic similarity and offspring performance in blue tits in relation to brood size manipulation

Aneta Arct, Szymon Drobniak, Samantha Mellinger, Lars Gustafsson & Mariusz Cichon
In birds, as in many other taxa, the level of genetic similarity between parents is an important source of variation in offspring fitness. The majority of avian studies which explore the influence of mates’ genetic similarity on offspring viability have focused on hatching success as a viability measure. Yet, viability benefits may extend into later life stages, including the nestling period and beyond. Here, we analysed data from free-living blue tits (Cyanistes caeruleus) across three...

Data from: Structural consequence of the most frequently recurring cancer-associated substitution in DNA polymerase ε

Vimal Parkash, Yashraj Kulkarni, Josy Ter Beek, Polina V. Shcherbakova, Shina C. L. Kamerlin & Erik Johansson
The most frequently recurring cancer-associated DNA polymerase ε (Pol ε) mutation is a P286R substitution in the exonuclease domain. While originally proposed to increase genome instability by disrupting exonucleolytic proofreading, the P286R variant was later found to be significantly more pathogenic than Pol ε proofreading deficiency per se. The mechanisms underlying its stronger impact remained unclear. Here we report the crystal structure of the yeast orthologue, Pol ε−P301R, complexed with DNA and an incoming dNTP....

Dietary Restriction Improves Fitness of Aging Parents But Reduces Fitness of Their Offspring in Nematodes

Brian Mautz, Martin I Lind & Alexei A Maklakov
Abstract Dietary restriction (DR) is a well-established intervention to extend lifespan across taxa. Recent studies suggest that DR-driven lifespan extension can be cost-free, calling into question a central tenant of the evolutionary theory of aging. Nevertheless, boosting parental longevity can reduce offspring fitness. Such intergenerational trade-offs are often ignored but can account for the “missing costs” of longevity. Here, we use the nematode Caenorhabditis remanei to test for effects of DR by fasting on fitness...

Data from: Broad-scale patterns of the Afro-Palearctic landbird migration

Martins Briedis, Silke Bauer, Peter Adamík, José Alves, Joana Costa, Tamara Emmenegger, Lars Gustafsson, Jaroslav Koleček, Miloš Krist, Felix Liechti, Simeon Lisovski, Christoph Meier, Petr Procházka & Steffen Hahn
Aim: Animal migration strategies balance trade-offs between mortality and reproduction in seasonal environments. Knowledge of broad-scale biogeographical patterns of animal migration is important for understanding ecological drivers of migratory behaviours. Here we present a flyway-scale assessment of the spatial structure and seasonal dynamics of the Afro-Palearctic bird migration system and explore how phenology of the environment guides long-distance migration. Location: Europe and Africa. Time period: 2009–2017. Major taxa studied: Birds. Methods: We compiled an individual-based...

A genome-wide investigation of adaptations related to tool use behaviour in New Caledonian and Hawaiian crows

Nicolas Dussex, Verena E. Kutschera, R. Axel W. Wiberg, Darren Parker, Gavin Hunt, Russell D. Gray, Kim Rutherford, Abe Hideaki, Robert Fleischer, Christian Rutz, Michael G. Ritchie, Jochen B.W. Wolf & Neil J. Gemmell
GFF3 file with protein-coding gne predictions for the C. moneduloides de novo genome assembly (available at the National Center for Biotechnology Information (NCBI); assembly accession number: VRTO00000000), generated using the MAKER2 pipeline.

Distribution patterns of fungal taxa and inferred functional traits reflect the non-uniform vertical stratification of soil microhabitats in a coastal pine forest

Kerri Kluting, Karina Clemmensen, Stanislovas Jonaitis, Rimvydas Vasaitis, Sara Holmström, Roger Finlay & Anna Rosling
In boreal systems, soil profiles typically consist of distinct stratified horizons, with organic layers at the surface overlying deeper mineral horizons providing microhabitat variation along a depth gradient, and vertical stratification of fungal communities along such soil profiles is commonly observed. We studied fungal community structure in a coastal pine forest along a gradient of decreasing influence from the coast. In this system, the vertical stratification pattern of soil microhabitats (defined here as organic, mineral...

Data from: Cryptic genetic variation shapes the adaptive evolutionary potential of enzymes

Florian Baier, Nansook Hong, Gloria Yang, Anna Pabis, Charlotte M. Miton, Alexandre Barrozo, Paul D. Carr, Shina C. L. Kamerlin, Colin J. Jackson & Nobuhiko Tokuriki
Genetic variation among orthologous proteins can cause cryptic phenotypic properties that only manifest in changing environments. Such variation may impact the evolvability of proteins, but the underlying molecular basis remains unclear. Here, we performed comparative directed evolution of four orthologous metallo-β-lactamases toward a new function and found that different starting genotypes evolved to distinct evolutionary outcomes. Despite a low initial fitness, one ortholog reached a significantly higher fitness plateau than its counterparts, via increasing catalytic...

Data from: Genotype-free estimation of allele frequencies reduces bias and improves demographic inference from RADSeq data

Vera Warmuth, Hans Ellegren & Vera M. Warmuth
Restriction-site associated sequencing (RADSeq) facilitates rapid generation of thousands of genetic markers at relatively low cost; however, several sources of error specific to RADSeq methods often lead to biased estimates of allele frequencies and thereby to erroneous population genetic inference. Estimating the distribution of sample allele frequencies without calling genotypes was shown to improve population inference from whole genome sequencing data, but the ability of this approach to account for RADSeq-specific biases remains unexplored. Here...

Data from: Damage shielding mechanisms in hierarchical composites in nature with potentials in design of tougher structural materials

Otte Marthin & Kristofer Gamstedt
Load-carrying materials in nature, such as wood and bone, consist of relatively simple building blocks assembled into a hierarchical structure, ranging from the molecular scale up to the macroscopic level. This results in composites with a combination of high strength and high toughness, showing very large fracture surfaces indicating energy dissipation by cracking on multiple length scales. Manmade composites instead consists typically of fibres embedded in a uniform matrix, and frequently shows brittle failure through...

Data from: Conflicting selection on floral scent emission in the orchid Gymnadenia conopsea

Elodie B. Chapurlat, Jon Ågren, Joseph Anderson, Magne Friberg & Nina Sletvold
• Floral scent is a crucial trait for pollinator attraction. Yet, only a handful of studies have estimated selection on scent in natural populations and no study has quantified the relative importance of pollinators versus other agents of selection.• In the fragrant orchid Gymnadenia conopsea s.s., we used electroantennographic data to identify floral scent compounds detected by local pollinators and quantified pollinator-mediated selection on emission rates of ten target compounds as well as on flowering...

Data from: Predation selects for smaller eye size in a vertebrate: effects of environmental conditions and sex

Richard Svanback & Frank Johansson
Increased eye size in animals results in a larger retinal image and thus improves visual acuity. Thus, larger eyes should aid both in finding food as well as detecting predators. On the other hand, eyes are usually very conspicuous and several studies have suggested that eye size is associated with predation risk. However, experimental evidence is scanty. In this study, we address how predation affects variation in eye size by performing two experiments using Eurasian...

Intraspecific mating system evolution and its effect on complex male secondary sexual traits: does male-male competition increase selection on size or shape?

Julian Baur, Jeannine Roy, Martin A. Schäfer, Nalini Puniamoorthy, Wolf U. Blanckenhorn & Patrick T. Rohner
Sexual selection is generally held responsible for the exceptional diversity in secondary sexual traits in animals. Mating system evolution is therefore expected to profoundly affect the covariation between secondary sexual traits and mating success. While there is such evidence at the interspecific level, data within species remain scarce. We here investigate sexual selection acting on the exaggerated male fore femur and the male wing in the common and widespread dung flies Sepsis punctum and S....

Data from: Earth history and the passerine superradiation

Carl H. Oliveros, Daniel J. Field, Daniel T. Ksepka, F. Keith Barker, Alexandre Aleixo, Michael J. Andersen, Per Alström, Brett W. Benz, Edward L. Braun, Michael J. Braun, Gustavo A. Bravo, Robb T. Brumfield, R. Terry Chesser, Santiago Claramunt, Joel Cracraft, Andrés M. Cuervo, Elizabeth P. Derryberry, Travis C. Glenn, Michael G. Harvey, Peter A. Hosner, Leo Joseph, Rebecca T. Kimball, Andrew L. Mack, Colin M. Miskelly, A. Townsend Peterson … & Brant C. Faircloth
Avian diversification has been influenced by global climate change, plate tectonic movements, and mass extinction events. However, the impact of these factors on the diversification of the hyperdiverse perching birds (passerines) is unclear because family level relationships are unresolved and the timing of splitting events among lineages is uncertain. We analyzed DNA data from 4,060 nuclear loci and 137 passerine families using concatenation and coalescent approaches to infer a comprehensive phylogenetic hypothesis that clarifies relationships...

Data from: Does thermal plasticity align with local adaptation? – An interspecific comparison of wing morphology in sepsid flies

Patrick T. Rohner, Jeannine Roy, Martin A. Schäfer, Wolf U. Blanckenhorn & David Berger
Although genetic and plastic responses are sometimes considered as unrelated processes, their phenotypic effects may often align because genetic adaptation is expected to mirror phenotypic plasticity if adaptive, but run counter to it when maladaptive. The magnitude and direction of this alignment has further consequences for both the tempo and mode of adaptation. To better understand the interplay between phenotypic plasticity and genetic change in mediating adaptive phenotypic variation to climate variability, we here quantified...

Data from: Modelling durophagous predation and mortality rates from the fossil record of gastropods

Graham E. Budd & Richard P. Mann
Gastropods often show signs of unsuccessful attacks by durophagous predators in the form of healed scars in their shells. As such, fossil gastropods can be taken as providing a record of predation through geological time. However, interpreting the number of such scars has proved to be problematic - would a low number of scars mean a low rate of attack, or a high rate of success, for example? Here we develop a model of population...

Data from: The efficacy of good genes sexual selection under environmental change

Ivain Martinossi-Allibert, Claus Rueffler, Göran Arnqvist & David Berger
Sexual selection can promote adaptation if sexually selected traits are reliable indicators of genetic quality. Moreover, models of good genes sexual selection suggest that, by operating more strongly in males than in females, sexual selection may purge deleterious alleles from the population at a low demographic cost, offering an evolutionary benefit to sexually reproducing populations. Here, we investigate the effect of good genes sexual selection on adaptation following environmental change. We show that the strength...

Data from: A full annual perspective on sex-biased migration timing in long-distance migratory birds

Martins Briedis, Silke Bauer, Peter Adamik, José A. Alves, Joana S. Costa, Tamara Emmenegger, Lars Gustafsson, Jaroslav Koleček, Felix Liechti, Christoph M. Meier, Petr Prochazka & Steffen Hahn
In many taxa, the most common form of sex-biased migration timing is protandry – the earlier arrival of males at breeding areas. Here we test this concept across the annual cycle of long-distance migratory birds. Using more than 350 migration tracks of small-bodied trans-Saharan migrants, we quantify differences in male and female migration schedules and test for proximate determinants of sex-specific timing. In spring, males on average departed from the African non-breeding sites about 3...

Data from: Pipefish embryo oxygenation, survival and development: egg size, male size and temperature effects

Malin Nygård, Charlotta Kvarnemo, Ingrid Ahnesjö & Ines Braga Goncalves
In animals with uniparental care, the quality of care provided by one sex can deeply impact the reproductive success of both sexes. Studying variation in parental care quality within a species and which factors may affect it can therefore shed important light on patterns of mate choice and other reproductive decisions observed in nature. Using Syngnathus typhle, a pipefish species with extensive uniparental male care, with embryos developing inside a brood pouch during a lengthy...

Data from: Size-mediated priority and temperature effects on intra-cohort competition and cannibalism in a damselfly

Szymon Sniegula, Maria J. Golab & Frank Johansson
1. A shift in the relative arrival of offspring, e.g., a shift in hatching time, can affect competition at the intraspecific level through size-mediated priority effects, where the larger individuals gain more resources. These priority effects are likely to be affected by climate warming and the rate of intraspecific predation, i.e., cannibalism. 2. In a laboratory experiment, we examined size-mediated priority effects in larvae of the univoltine damselfly, Lestes sponsa, at two different temperatures (21°C...

Data from: Effects of photoperiod on life-history and thermal stress resistance traits across populations of Drosophila subobscura

Neda N. Moghadam, Zorana K. Novicic, Cino Pertoldi, Torsten N. Kristensen & Simon Bahrndorff
Intro: Organisms use environmental cues to match their phenotype with the future availability of resources and environmental conditions. Changes in the magnitude and frequency of environmental cues such as photoperiod and temperature along latitudes can be used by organisms to predict seasonal changes. While the role of temperature variation on the induction of plastic and seasonal responses is well established, the importance of photoperiod for predicting seasonal changes is less explored. M&M: Here we studied...

Data from: Fusion pore regulation by cAMP/Epac2 controls cargo release during insulin exocytosis

Alenka Guček, Nikhil R. Gandasi, Muhmmad Omar-Hmeadi, Marit Bakke, Stein O. Døskeland, Anders Tengholm & Sebastian Barg
Regulated exocytosis establishes a narrow fusion pore as initial aqueous connection to the extracellular space, through which small transmitter molecules such as ATP can exit. Co-release of polypeptides and hormones like insulin requires further expansion of the pore. There is evidence that pore expansion is regulated and can fail in diabetes and neurodegenerative disease. Here we report that the cAMP-sensor Epac2 (Rap-GEF4) controls fusion pore behavior by acutely recruiting two pore-restricting proteins, amisyn and dynamin-1,...

Registration Year

  • 2019
    40

Resource Types

  • Dataset
    40

Affiliations

  • Uppsala University
    40
  • University of Zurich
    3
  • University of Aveiro
    2
  • University of Cambridge
    2
  • Swedish University of Agricultural Sciences
    2
  • Jagiellonian University
    2
  • Swiss Ornithological Institute
    2
  • Palacký University, Olomouc
    2
  • University of Bristol
    2
  • Academy of Sciences of the Czech Republic
    2