40 Works

Data from: Structural classification and scaffold diversity of sesquiterpene lactones in the angiosperms

Astrid Henz Ryen, Rosa Buonfiglio, Anders Backlund & Thierry Kogej
Sesquiterpene lactones (STLs) present one of the largest groups of plant specialized metabolites with a wide range of biological activities. They are a valuable source for new plant derived drugs and drug leads since they contain several important chemical properties responsible for their versatile therapeutic potential. The aim of this study was to analyze and compare the chemical diversity of all types of STLs in different plant groups, both qualitatively and quantitatively. For this purpose,...

Gene flow limits adaptation along steep environmental gradients

Judith Bachmann, Alexandra Jansen Van Rensburg, Maria Cortazar-Chinarro, Anssi Laurila & Josh Van Buskirk
When environmental variation is spatially continuous, dispersing individuals move among nearby sites with similar habitat conditions. But as an environmental gradient becomes steeper, gene flow may connect more divergent habitats, and this is predicted to reduce the slope of the adaptive cline that evolves. We compared quantitative genetic divergence of Rana temporaria frog populations along a 2000-m elevational gradient in eastern Switzerland (new experimental results) with divergence along a 1550-km latitudinal gradient in Fennoscandia (previously...

Data from: Sex-biased gene expression, sexual antagonism and levels of genetic diversity in the collared flycatcher (Ficedula albicollis) genome

Ludovic Dutoit, Carina Mugal, Paulina Bolivar, Mi Wang, Krystyna Nadachowska-Brzyska, Linnea Smeds, Homa Papoli, Lars Gustavsson & Hans Ellegren
Theoretical work suggests that sexual conflict should promote the maintenance of genetic diversity by the opposing directions of selection on males and females. If such conflict is pervasive, it could potentially lead to genomic heterogeneity in levels of genetic diversity an idea that so far has not been empirically tested on a genome-wide scale. We used large-scale population genomic and transcriptomic data from the collared flycatcher (Ficedula albicollis) to analyse how sexual conflict, for which...

Towards a comparative approach to the structure of animal personality variation

Stephen White, David Pascall & Alastair Wilson
Latent personality traits underpinning observed behavioral variation have been studied in a great many species. However, a lack of standardized behavioral assays, coupled to a common reliance on inferring personality from a single, observed, behavioral trait makes it difficult to determine if, when, and how conclusions can be directly compared across taxa. Here, we estimate the among-individual (co)variance structure (ID) for a set of four behaviors expressed in an open field trial, putatively indicative of...

Data from: Genetic basis of amphibian larval development along a latitudinal gradient: gene diversity, selection and links with phenotypic variation in transcription factor C/EBP-1

Yvonne Meyer-Lucht, Emilien Luquet, Frida Johannesdottir, Patrik Rödin-Mörch, Maria Quintela, Alex Richter-Boix, Jacob Höglund & Anssi Laurila
Ectotherm development rates often show adaptive divergence along climatic gradients, but the genetic basis for this variation is rarely studied. Here, we investigated the genetic basis for phenotypic variation in larval development in the moor frog Rana arvalis from five regions along a latitudinal gradient from Germany to northern Sweden. We focused on the C/EBP-1 gene, a transcription factor associated with larval development time. Allele frequencies at C/EBP-1 varied strongly among geographic regions. Overall, the...

Data from: Climbing adaptations, locomotory disparity and ecological convergence in ancient stem ‘kangaroos’

Wendy Den Boer, Nicolas E. Campione & Benjamin P. Kear
Living kangaroos, wallabies and rat-kangaroos (Macropodoidea) constitute the most ecologically diverse radiation of Australasian marsupials. Indeed, even their hallmark bipedal hopping gait has been variously modified for bounding, walking, and climbing. However, the origins of this locomotory adaptability are uncertain because skeletons of the most ancient macropodoids are exceptionally rare. Some of the stratigraphically oldest fossils have been attributed to Balbaridae — a clade of potentially quadrupedal stem macropodoids that became extinct during the late...

Data from: Selection for novel metabolic capabilities in Salmonella enterica

Omar Warsi, Erik Lundin, Ulrika Lustig, Joakim Näsvall & Dan Andersson
Bacteria are known to display extensive metabolic diversity and many studies have shown that they can use an extensive repertoire of small molecules as carbon- and energy sources. However, it is less clear to what extent a bacterium can expand its existing metabolic capabilities by acquiring mutations that, for example, rewire its metabolic pathways. To investigate this capability and potential for evolution of novel phenotypes, we sampled large populations of mutagenized Salmonella enterica to select...

Data from: Birds with high lifetime reproductive success experience increased telomere loss

Joanna Sudyka, Aneta Arct, Szymon M. Drobniak, Lars Gustafsson & Mariusz Cichoń
Lifetime reproductive success (LRS) is what counts in terms of evolution, but investments in reproduction entail costs for an organism. The idea that telomere dynamics may be shaped in response to such costs is already established, however we still lack information if this relation translates to overall fitness. Here, we quantified lifetime reproductive success (number of fledged young) and longitudinal telomere dynamics of small passerine birds - the blue tits. We found that individual telomere...

Data from: Selection for longer-lived sperm within ejaculate reduces reproductive ageing in offspring

Ghazal Alavioon, Andrea Cabrera Garcia, Magali LeChatelier, Alexei Maklakov & Simone Immler
Males produce numerous sperm in a single ejaculate that greatly outnumber their potential egg targets. Recent studies found that phenotypic and genotypic variation among sperm in a single ejaculate of a male affects the fitness and performance of the resulting offspring. Specifically, within-ejaculate sperm selection for sperm longevity increased the performance of the resulting offspring in several key life-history traits in early-life. Because increased early-life reproductive performance often correlates with rapid ageing, it is possible...

Data from: Exploring a Pool-seq only approach for gaining population genomic insights in non-model species

Sara Kurland, Chris Wheat, Maria De La Paz Celorio-Mancera, Verena Kutschera, Jason Hill, Anastasia Andersson, Carl Johan Rubin, Leif Andersson, Nils Ryman & Linda Laikre
Developing genomic insights is challenging in non-model species for which resources are often scarce and prohibitively costly. Here, we explore the potential of a recently established approach using Pool-seq data to generate a de novo genome assembly for mining exons, upon which Pool-seq data is used to estimate population divergence and diversity. We do this for two pairs of sympatric populations of brown trout (Salmo trutta); one naturally sympatric set of populations and another pair...

How does joint evolution of consumer traits affect resource specialization?

Paula Vasconcelos & Claus Rueffler
Consumers regularly experience trade-offs in their ability to find, handle and digest different resources. Evolutionary ecologists recognized the significance of this observation for the evolution and maintenance of biological diversity long ago and continue to elaborate on the conditions under which to expect one or several specialists, generalists or combinations thereof. Existing theory based on a single evolving trait predicts that specialization requires strong trade-offs such that generalists perform relatively poorly, while weak trade-offs favor...

Data from: Stabilizing selection and adaptive evolution in a combination of two traits in an arctic ungulate

Håkon Holand, Thomas Kvalnes, Knut Røed, Øystein Holand, Bernt-Erik Sæther & Jouko Kumpula
Stabilizing selection is thought to be common in wild populations and act as one of the main evolutionary mechanisms which constrain phenotypic variation. When multiple traits interact to create a combined phenotype, correlational selection may be an important process driving adaptive evolution. Here we report on phenotypic selection and evolutionary changes in two natal traits in a semi-domestic population of reindeer (Rangifer tarandus) in northern Finland. The population has been closely monitored since 1969, and...

Quantifying the structure and dynamics of fish shoals under predation threat in three-dimensions

Maksym Romenskyy, James Herbert-Read, Christol Ioannou, Alex Szorkovszky, Ashley Ward & David Sumpter
Detailed quantifications of how predators and their grouping prey interact in three dimensions (3D) remain rare. Here we record the structure and dynamics of fish shoals (Pseudomugil signifer) in 3D both with and without live predators (Philypnodon grandiceps) under controlled laboratory conditions. Shoals adopted two distinct types of shoal structure; ‘sphere-like’ geometries at depth, and flat ‘carpet-like’ structures at the water’s surface, with shoals becoming more compact in both horizontal and vertical planes in the...

Data from: Antibiotic uptake across gram-negative outer membranes: better predictions towards better antibiotics

Peter Kasson & Ricardo Ferreira
Crossing the gram-negative bacterial membrane poses a major barrier to antibiotic development, as many small molecules that can biochemically inhibit key bacterial processes are rendered microbiologically ineffective by their poor cellular uptake. The outer membrane is the major permeability barrier for many drug-like molecules, and the chemical properties that enable efficient uptake into mammalian cells fail to predict bacterial uptake. We have developed a computational method for accurate prospective prediction of outer-membrane uptake of drug-like...

Data from: Footprints of adaptive evolution revealed by whole Z chromosomes haplotypes in flycatchers

Krystyna Nadachowska-Brzyska, Reto Burri & Hans Ellegren
Detecting positive selection using genomic data is critical to understanding the role of adaptive evolution. Of particular interest in this context is sex chromosomes since they are thought to play a special role in local adaptation and speciation. We sought to circumvent the challenges associated with statistical phasing when using haplotype-based statistics in sweep scans by benefitting from that whole-chromosome haplotypes of the sex chromosomes can be obtained by re-sequencing of individuals of the hemizygous...

Registration Year

  • 2019

Resource Types

  • Dataset


  • Uppsala University
  • University of Zurich
  • University of Aveiro
  • University of Cambridge
  • Swedish University of Agricultural Sciences
  • Jagiellonian University
  • Swiss Ornithological Institute
  • Palacký University, Olomouc
  • University of Bristol
  • Academy of Sciences of the Czech Republic