2 Works

Roundup causes high levels of mortality following contact exposure

Edward Straw, Edward Carpentier & Mark Brown
1. Pollinators underpin global food production, but they are suffering significant declines across the world. Pesticides are thought to be important drivers of these declines. Herbicides are the most widely applied type of pesticides and are broadly considered ‘bee safe’ by regulatory bodies who explicitly allow their application directly onto foraging bees. We aimed to test the mortality effects of spraying the world’s most popular herbicide brand (Roundup®) directly onto bumble bees (Bombus terrestris audax)....

Association of SUMOlation pathway genes with stroke in a genome-wide association study in India

Amit Kumar, Ganesh Chauhan, Shriram Sharma, Surekha Dabla, P. N. Sylaja, Neera Chaudhary, Salil Gupta, Chandra Sekhar Agrawal, Kuljeet Singh Anand, Achal Kumar Srivastava, Deepti Vibha, Ram Sagar, Ritesh Raj, Ankita Maheswari, Subbiah Vivekanandhan, Bhavna Kaul, Samudrala Raghavan, Sankar Prasad Gorthi, Dheeraj Mohania, Samander Kaushik, Rohtas Kanwar Yadav, Anjali Hazarika, Pankaj Sharma & Kameshwar Prasad
Objective: To undertake a genome-wide association study (GWAS) to identify genetic variants for stroke in Indians. Methods: In a hospital-based case-control study, eight teaching hospitals in India recruited 4,088 subjects, including 1,609 stroke cases. Imputed genetic variants were tested for association with stroke subtypes using both single-marker and gene-based tests. Association with vascular risk factors was performed using logistic regression. Various databases were searched for replication, functional annotation, and association with related traits. Status of...

Registration Year

  • 2021
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  • Dataset
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Affiliations

  • University of London
    2
  • Dr. Ram Manohar Lohia Hospital
    1
  • Sir Ganga Ram Hospital
    1
  • All India Institute of Medical Sciences
    1
  • Maharshi Dayanand University
    1
  • Vardhman Mahavir Medical College & Safdarjung Hospital
    1
  • Indian Institute of Science Bangalore
    1
  • Army Hospital Research and Referral
    1
  • Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences
    1
  • Sree Chitra Thirunal Institute for Medical Sciences and Technology
    1