37 Works

Association of Serum Paraoxonase/Arylesterase Activity With All-Cause Mortality in Maintenance Hemodialysis Patients

Yasunori Suematsu, Masaki Goto, Christina Park, Ane C.F. Nunes, WangHui Jing, Elani Streja, Connie M. Rhee, Siobanth Cruz, Moti L. Kashyap, Nosratola D. Vaziri, Vasanthy Narayanaswami, Kamyar Kalantar-Zadeh & Hamid Moradi
Context: In end-stage renal disease (ESRD), serum high-density lipoprotein cholesterol (HDL-C) level is not an accurate predictor of mortality, partly because it does not necessarily correlate with indices of HDL function. Paraoxonase (PON) is a major enzyme constituent of HDL and key component of HDL antioxidant activity. Apolipoprotein (Apo) A-I is the core HDL structural protein that plays a major role in various aspects of HDL function. Objective: We sought to examine PON activity and...

Data from: Multichannel Stroboscopic Videography (MSV): A technique for visualizing multiple channels for behavioral measurements.

Alberto Soto, Matthew McHenry & Theodora Po
Biologists commonly visualize dierent features of an organism using distinct sources of illumination. Multichannel imaging has largely not been applied to behavioral studies due to the challenges posed by a moving subject. We address this challenge with the technique of Multichannel Stroboscopic Videography (MSV), which synchronizes multiple strobe lights with video exposures of a single camera. We illustrate the utility of this approach with kinematic measurements of a walking cockroach (Gromphadorhina portentosa) and calculations of...

Data from: Elevational cline in herbivore abundance driven by a monotonic increase in trophic level sensitivity to aridity

Annika S. Nelson, Cole T. Symanski, Matthew J. Hecking & Kailen A. Mooney
1. The abiotic environment drives species abundances and distributions both directly and indirectly through effects on multi-trophic species interactions. However, few studies have documented the individual and combined consequences of these direct and indirect effects. 2. We studied an ant-tended aphid along an elevational gradient, where lower elevations were more arid. Hypotheses of stronger species interactions at lower elevations and a greater sensitivity of higher trophic levels to climate led us to predict increased top-down...

Code and data from: Evolution of sexual cooperation from sexual conflict

Maria R Servedio, John M Powers, Russell Lande & Trevor D Price
This C code conducts deterministic iterations of the exact recursion equations presented in the Model section of "Evolution of sexual cooperation from sexual conflict" by Servedio, Powers, Lande and Price. The code produces a two-dimensional grid with any parameters of choice on the x and y axis. Examples can be found in Figures 2c, 3c and 4 of the main text as well as many similar figures in the Supplementary Material. A sample parameter file...

Positive allosteric modulation of the α7 nicotinic acetylcholine receptor as a treatment for cognitive deficits after traumatic brain injury

David Titus, Timothy Johnstone, Nathan Johnson, Sidney London, Meghana Chapalamadugu, Derk Hogenkamp, Kelvin Gee & Coleen Atkins
Cognitive impairments are a common consequence of traumatic brain injury (TBI). The hippocampus is a subcortical structure that plays a key role in the formation of declarative memories and is highly vulnerable to TBI. The α7 nicotinic acetylcholine receptor (nAChR) is highly expressed in the hippocampus and reduced expression and function of this receptor are linked with cognitive impairments in Alzheimer’s disease and schizophrenia. Positive allosteric modulation of α7 nAChRs with AVL-3288 enhances receptor currents...

Figures for \"California forest die-off linked to multi-year deep soil drying in 2012-2015 drought\"

Michael Goulden
Data underlying main figures in "California forest die-off linked to multi-year deep soil drying in 2012-2015 drought", published in Nature-Geoscience, July 2019, ML Goulden and RC Bales. Abstract of paper: Widespread episodes of recent forest die-off have been tied to the occurrence of anomalously warm droughts, though the underlying mechanisms remain inadequately understood. California’s 2012-2015 drought, with exceptionally low precipitation and warmth and widespread conifer death, provides an opportunity to explore the chain of events...

Environmental drivers of adult locomotion and reproduction in a symbiont-hosting sea anemone

Samuel Bedgood
This data was collected from the sea anemone species Exaiptasia diaphana collected in the Florida Keys in January 2016. Anemones were brought into the lab where they were exposed to feeding treatments (fed or starved) and algal symbiont manipulations (high or low symbiont denisties). We collected data on movement via time lapse photography, reproduction via counting of pedal lacerates, and anemone size via photography and analysis in the program ImageJ. We found that feeding treatments...

Rhythm of Attention

Haleh Farahbod, Kourosh Saberi & Gregory Hickok
Modulation patterns are known to carry critical predictive cues to signal detection in complex acoustic environments. The current study investigated the persistence of masker modulation effects on post-modulation detection of probe signals. Hickok et al. (2015) demonstrated that thresholds for a tone pulse in stationary noise follow a predictable periodic pattern when preceded by a 3-Hz amplitude modulated masker. They found entrainment of detection patterns to the modulation envelope lasting for approximately 2 cycles after...

Solar-J and Cloud-J models version 7.6c

Michael Prather & Juno Hsu
This dataset includes the models (fortran code, matlab code, data) used to simulate the heating and photolysis rates in a spherical atmosphere. Both Solar-J v7.5 and Cloud-J v7.3c have been published previously, but with the publication of Prather and Hsu, "A round Earth for climate models" in PNAS (2019) both models have been merged in terms of overlapping subroutines and both now include option for (0) a flat-Earth atmosphere, (1) solar ray tracing through a...

Grounding line of Denman Glacier, East Antarctica from satellite radar interferometry

Virginia Brancato, Eric Rignot, Pietro Milillo, Mathieu Morlighem, Jeremie Mouginot, Lu An, Bernd Scheuchl, Seong Su Jeong, Paola Rizzoli, Jose Luiz Bueso Bello & Pau Prats-Iraola
Grounding line, elevation changes, and melt rates maps of Denman Glacier, East Antarctica. Using satellite radar interferometry from the COSMO-SkyMed mission we map the grounding line of Denman Glacier, East Antarctica. We complement these data with some historical interferometric radar acquisition from the European satellite ERS-1/2. We present new maps of elevation changes on the grounded and floating portions of Denman Glacier obtained by temporally differencing TanDEM-X Digital Elevation Models.

Aerosol particle measurements taken during the airborn ARISTO 2016 campaign.

John Ortega, James Smith, Jefferson Snider & J. Michael Reeves
Several different types of measurements of particle size and concentration were compared during the 2016 Airborne Research Instrumentation Testing Opportunity (ARISTO) campaign. The scanning mobility particle sizer (SMPS) measured number-size distributions for mobility diameters between ~20-350 nm or ~8-110 nm, depending on the mobility analyzer chosen. Also included were two stand-alone condensation particle counters (CPC) for determining size-integrated particle concentrations. A wing-mounted and a rack-mounted Ultra-High Sensitivity Aerosol Spectrometer (UHSAS) were used to measure size...

Crystal Cove Marine Conservation Area Science Monitoring

Conservancy Crystal Cove
Crystal Cove Conservancy operates the Crystal Cove Marine Protected Area Science Cruise in partnership with Newport Landing Sportfishing. Under the supervision of trained Crystal Cove Conservancy staff, junior high school and high school students collect data on fish and plankton biodiversity and nearshore water quality in the Crystal Cove Marine Conservation Area, following protocols designed in partnership with UCI and other researchers. See README file for more detailed information. “Data made available in the OC...

Data from: Diet variability among insular populations of Podarcis lizards reveals diverse strategies to face resource-limited environments

Maxime Taverne, Anne-Claire Fabre, Nina King-Gillies, Marija Krajnović, Duje Lisičić, Louise Martin, Leslie Michal, Donat Petricioli, Anamaria Stambuk, Zoran Tadić, Chloé Vigliotti, Beck Wehrle & Anthony Herrel
Access to resources is a dynamic and multi-causal process that determines the success and survival of a population. It is therefore often challenging to disentangle the factors affecting ecological traits like diet. Insular habitats provide a good opportunity to study how variation in diet originates, in particular in populations of mesopredators such as lizards. Indeed, high levels of population density associated with low food abundance and low predation are selection pressures typically observed on islands....

Data from: Insensitivity of the cloud response to surface warming under radical changes to boundary layer turbulence and cloud microphysics: results from the ultraparameterized CAM

Hossein Parishani
This data set contains the simulation outputs used in the study summarized below: We study the cloud response to a +4K surface warming in a new multiscale climate model that uses enough interior resolution to begin explicitly resolving boundary layer turbulence (i.e., ultraparameterization or UP). UP's predictions are compared against those from standard superparameterization (SP). The mean cloud radiative effect feedback turns out to be remarkably neutral across all of our simulations, despite some radical...

Flood Resilient Infrastructure and Sustainable Environments (FloodRISE) data

Jochen Schubert
Existing needs to manage flood risk in the U.S. are underserved by available flood hazard information. This contributes to an alarming escalation of flood impacts that amount to hundreds of billions of dollars per year and countless disrupted lives and affected communities. Making information about flood hazards useful for the range of decisions by actors that dictate the consequences of flooding poses many challenges. This dataset contains a collection of flood hazard mapping layers for...

Classification of Type 2 Diabetes Genetic Variants and a Novel Genetic Risk Score Association with Insulin Clearance

Mark Goodarzi, Nicholette D Palmer, Jinrui Cui, Xiuqing Guo, Yii-Der I Chen, Kent D Taylor, Leslie J Raffel, Lynne E Wagenknecht, Thomas A Buchanan, Willa A Hsueh & Jerome I Rotter
Abstract Context Genome-wide association studies have identified >450 single nucleotide polymorphisms (SNPs) for type 2 diabetes (T2D). Objective To facilitate use of these SNPs in future genetic risk score (GRS)-based analyses, we aimed to classify the SNPs based on physiology. We also sought to validate GRS associations with insulin-related traits in deeply-phenotyped Mexican Americans. Design, Setting, and Participants 457 T2D SNPs from the literature were assigned physiologic function based on association studies and cluster analyses....

Data from: A phase 3 randomized study evaluating sialic acid extended-release for GNE myopathy

Hanns Lochmüller, Anthony Behin, Yoseph Caraco, Heather Lau, Massimiliano Mirabella, Ivailo Tournev, Mark Tarnopolsky, Oksana Pogoryelova, Catherine Woods, Alexander Lai, Jinay Shah, Tony Koutsoukos, Alison Skrinar, Hank Mansbach, Emil Kakkis & Tahseen Mozaffar
Objective: To investigate the efficacy and safety of aceneuramic acid extended-release (Ace-ER), a treatment intended to replace deficient sialic acid, in patients with GNE myopathy. Methods: UX001-CL301 was a Phase 3, double-blind, placebo-controlled, randomized, international study evaluating the efficacy and safety of Ace-ER in patients with GNE Myopathy. Participants who could walk ≥200 meters in a 6-minute walk test at screening were randomized 1:1, and stratified by sex, to receive Ace-ER 6g/day or placebo for...

UCI Libraries chatbot Transcripts (ANTswers)

Danielle Kane
ANTswers is an experimental chatbot that can answer questions about the UC Irvine Libraries. ANTswers is a web-based application, run on a remote library server and is accessed through a web interface page. ANTswers’ personality and persona is based on the UCI mascot, Peter the Anteater. ANTswers responds to simple and short questions. The first link in a response opens in a preview window, all other links open in a new window. Each transaction is...

Serum Endocannabinoid Levels in Patients With End-Stage Renal Disease

Hamid Moradi, Christina Park, Miki Igarashi, Elani Streja, Donovan A. Argueta, Melissa Soohoo, Jennifer Daglian, Amy S. You, Connie M. Rhee, Moti L. Kashyap, Nicholas V. DiPatrizio, Nosratola D. Vaziri, Kamyar Kalantar-Zadeh & Daniele Piomelli
Context: Previous studies have shown that the endocannabinoid system plays a major role in energy metabolism through the actions of its main mediators, 2-arachidonoyl-sn-glycerol (2-AG) and anandamide (AEA). Objective: We examined serum levels of major endocannabinoid mediators and their association with clinical parameters in patients with end-stage renal disease (ESRD). Design and Setting: Serum concentrations of 2-AG and AEA were measured in patients on maintenance hemodialysis (MHD), and correlations with various clinical and laboratory indices...

Acetylene and ethane surface flask measurements from Cape Grim, Australia and South Pole, Antarctica

Melinda Nicewonger, Murat Aydin & Eric Saltzman
Measurements of the abundance of acetylene and ethane in surface air flasks from Cape Grim, Australia (CGO) and South Pole, Antarctica (SPO) were made in the Saltzman/Aydin Research Group at the University of California, Irvine. The surface flasks are from the the NOAA Halocarbons and other Atmospheric Trace Species (HATS) monitoring network shared with UC Irvine by Dr. Stephen Montzka to compliment on-going ice core research at UC Irvine involving the same trace species.

Toward low-cloud-permitting cloud superparameterization with explicit boundary layer turbulence -- simulation data

Hossein Parishani, Michael Pritchard, Christopher Bretherton, Matthew Wyant & Marat Khairoutdinov
This data set contains the simulation outputs used in the study summarized below: Systematic biases in the representation of boundary layer (BL) clouds are a leading source of uncertainty in climate projections. A variation on superparameterization (SP) called ‘‘ultraparameterization’’ (UP) is developed, in which the grid spacing of the cloud-resolving models (CRMs) is fine enough (250x20 m) to explicitly capture the BL turbulence, associated clouds, and entrainment in a global climate model capable of multiyear...

Eddy flux measurements and transfer velocities of momentum, water vapor, and sulfur dioxide over the coastal Atlantic ocean

Eric Saltzman
This data set contains air/sea eddy covariance fluxes and related data measured at the US Army Corps of Engineers Field Research Facility (USACE FRF) at Duck, North Carolina. The goal of this study was to determine transfer velocities for momentum, water vapor, and sulfur dioxide in order to study the processes controlling air/sea deposition of highly soluble gases. The measurements were made during March and April, 2015.

Data from: Physician champions’ perspectives and practices on electronic health records implementation: challenges and strategies

Xinning Gui, Yunan Chen, Xiaomu Zhou, Tera L. Reynolds, Kai Zheng & David A. Hanauer
Objective: Physician champions are “boots on the ground” physician leaders who facilitate the implementation of, and transition to, new health information technology (HIT) systems within an organization. They are commonly cited as key personnel in HIT implementations, yet little research has focused on their practices and perspectives. Methods: We addressed this research gap through a qualitative study of physician champions that aimed to capture their challenges and strategies during a large-scale HIT implementation. Email interviews...

Ice thickness and bed elevation of the Patagonian Icefields

Romain Millan
We combine airborne gravity data collected in 2012 and 2016, with WISE and CECs radar sounder data from 2014 and 2015 to map bed elevation and ice thickness accross the Northern and Southern Patagonian Icefields. We perform a three dimensional inversion of the gravity field constrained by radar-derived thickness, ice boundary, and fjord bathymetry to infer bed elevation at 500-m spacing, with a precision of about 50 m. The enclosed netCDF contains the following fields:...

Annual Ice Velocity of the Greenland Ice Sheet (2001-2010)

Jeremie Mouginot, Eric Rignot, Bernd Scheuchl, Michael Wood & Romain Millan
We derive surface ice velocity using data from 16 satellite sensors deployed by 6 different space agencies. The list of sensors and the year that they were used are listed in the following (Table S1). The SAR data are processed from raw to single look complex using the GAMMA processor (www.gamma-rs.ch). All measurements rely on consecutive images where the ice displacement is estimated from tracking or interferometry (Joughin et al. 1998, Michel and Rignot 1999,...

Registration Year

  • 2019

Resource Types

  • Dataset


  • University of California, Irvine
  • Jet Propulsion Lab
  • French National Centre for Scientific Research
  • Grenoble Alpes University
  • University of North Carolina
  • University of Chicago
  • University of Copenhagen
  • Bernardino Rivadavia Natural Sciences Museum
  • New Bulgarian University
  • California State University, Long Beach