zong non-coding RNAs (lncRNAs) have been identified as crucial effector in modulating the progression of assorted malignancies. In our study, the main aim was to unveil the role and the underlying regulatory mechanism of long intergenic non-protein coding RNA 1605 (LINC01605) in nasopharyngeal carcinoma (NPC). RT-qPCR analysis results suggested that LINC01605 was upregulated in NPC cells. According to the results of function experiments, LINC01605 promoted NPC cell proliferation and impeded cell apoptosis. The oncogenic role...

We present here the Bedmap2 ice thickness, bed and surface elevation standardised CSV data points that were used to create the Bedmap2 gridding products. The data consists of 25 million points coming from 68 individual surveys acquired in Antarctica. The associated datasets consist of: - Bedmap1 standardised CSV data points: https://doi.org/10.5285/f64815ec-4077-4432-9f55-0ce230f46029 - Bedmap3 standardised CSV data points: https://doi.org/10.5285/91523ff9-d621-46b3-87f7-ffb6efcd1847 - Bedmap2 statistically-summarised data points (shapefiles): https://doi.org/10.5285/0f90d926-99ce-43c9-b536-0c7791d1728b - Bedmap2 gridding products: https://doi.org/10.5285/fa5d606c-dc95-47ee-9016-7a82e446f2f2 This work is supported by...

Changes in some combination of niche availability, niche overlap and the strength of interspecific interactions are thought to drive changes in plant composition along resource gradients. However, because these processes are difficult to measure in the field, their relative importance in driving compositional change in plant communities remains unclear. In an Australian temperate grassland, we added seeds of three native and three exotic grasses to 1,875 experimental plots in a way that allowed us to...

Effective restoration planning tools are needed to mitigate global carbon and biodiversity crises. Published spatial assessments of restoration potential are often at large scales or coarse resolutions inappropriate for local action. Using a Tanzanian case study, we introduce a systematic approach to inform landscape restoration planning, estimating spatial variation in cost-effectiveness, based on restoration method, logistics, biomass modelling and uncertainty mapping. We found potential for biomass recovery across 77.7% of a 53,000 km2 region, but...

Additional file 3. Lists of bacterial and fungal OTUs identified as rhythmic through analysis of a 72-hour time-course under 12L12D.

Additional file 5: Table S4A. PHASTER prophage genome information. Table S4B. PhiSpy prophage genome information. Table S4C. Virsorter2 + CheckV prophage genome information. Table S4D. Combined PHASTER/PhiSpy/Virsorter2+CheckV hits with grouped prophages labels. Table S4E. De-duplicated prophage hits. Table S4F. Filtered PHASTER intact prophages with taxonomic labels and/or cross-tool validation.

Additional file 5: Table S4A. PHASTER prophage genome information. Table S4B. PhiSpy prophage genome information. Table S4C. Virsorter2 + CheckV prophage genome information. Table S4D. Combined PHASTER/PhiSpy/Virsorter2+CheckV hits with grouped prophages labels. Table S4E. De-duplicated prophage hits. Table S4F. Filtered PHASTER intact prophages with taxonomic labels and/or cross-tool validation.

Additional file 6: Table S5A. VIGA annotations of intact prophages. Table S5B. Megablast results of intact prophage metabolic genes (CAZy database). Table S5C. Megablast results of intact prophage type III effectors (Ralsto T3E database). Table S5D. Megablast results of intact prophage virulence factors (Phi-Base database). Table S5E. Predicted functions of abundant intact prophage hypothetical proteins using Structure-based function tool.

The large-scale expansion of built infrastructure is profoundly reshaping the geographies of Africa, generating lock-in patterns of development for future generations. Understanding the impact of these massive investments can allow development opportunities to be maximised and therefore be critical for attaining the United Nations Sustainable Development Goals and Africa Union Agenda 2063. However, until now information on the types, scope, and timing of investments, how they have evolved, and their spatial-temporal impact was dispersed amongst...

Electroadhesion provides a promising route to augment robotic functionalities with continuous, astrictive, and reversible adhesion force. However, the lack of suitable conductive/dielectric materials and processing capabilities have impeded the integration of electroadhesive modules into soft robots requiring both mechanical compliance and robustness. We present herein a novel iontronic adhesive based on a dynamically crosslinked gel-elastomer system, including an ionic organohydrogel as adhesive electrodes and a resilient polyurethane with high electrostatic energy density as dielectric layers....

Tropical peat swamp forests retain large carbon stocks and support unique biodiversity, but clearance and drainage for agriculture have resulted in fires, carbon emissions and biodiversity losses. Initiatives to re-wet cultivated peatlands may benefit biodiversity if this protects remaining forests from fire and agricultural encroachment, but there are concerns that re-wetting could reduce yields and damage livelihoods, as relationships between drainage, on-farm biodiversity, and crop yields have not been studied. We examined oil palm fruit...

The dataset comprises of physical and biogeochemical measurements of saltmarsh soils from across 22 UK saltmarshes. Between 2018 and 2021, 462 narrow diameter gouge cores (30 mm in diameter) were collected as part of the Carbon Storage in Intertidal Environments (C-SIDE) project to facilitate the calculation of saltmarsh soil organic carbon stocks. Sites were chosen to represent contrasting habitats types in the UK, in particular sediment types, vegetation and sea level history. The data provides...

Biological transportation networks must balance competing functional priorities. The self-organizing mechanisms used to generate such networks have inspired scalable algorithms to construct and maintain low-cost and efficient human-designed transport networks. The pheromone-based trail networks of ants have been especially valuable in this regard. Here, we use turtle ants as our focal system: In contrast to the ant species usually used as models for self-organized networks, these ants live in a spatially constrained arboreal environment where...

Estimating plasticity of leaf silicon (Si) in response to abiotic and biotic factors underpins our comprehension of plant defences and stress resistance in natural and agroecosystems. However, how nitrogen (N) addition and intraspecific plant-plant interactions affect Si accumulation remains unclear. We grew 19 durum wheat genotypes (Triticum turgidum ssp. durum) in pots, either alone, or in intra- or intergenotypic cultures of two individuals, and with or without N. Aboveground biomass, plant height and leaf [Si]...

Additional file 2: Table S1. RSSC isolates used in this study.

This dataset consists of landscape and agricultural management archetypes (1 km resolution) at three levels, defined by different opportunities for adaptation. Tier 1 archetypes quantify broad differences in soil, land cover and population across Great Britain, which cannot be readily influenced by the actions of land managers; Tier 2 archetypes capture more nuanced variations within farmland-dominated landscapes of Great Britain, over which land managers may have some degree of influence. Tier 3 archetypes are built...

This dataset details information collected from smallholder oil palm farms in Sabah, Malaysian Borneo. Including: management practices, oil palm fruit yield, understorey vegetation, and soil chemical properties (SOC, total N, total P and available P). We collected data between August to November 2019 from 40 smallholdings (defined as farms < 50 ha) across six governance areas in Sabah. We used responses from face-to-face questionnaires to collect information about their management practices, including Best Management Practices...

We present here the Bedmap2 ice thickness, bed and surface elevation aggregated points and survey lines. The aggregated points consist of statistically-summarised shapefile points (centred on a continent-wide 500 m x 500 m grid) that reports the average values of ice thickness, bed and surface elevation from the full-resolution survey data and information on their distribution. The points presented here correspond to the additional points to Bedmap1 used for the gridding of Bedmap2. The data...

Additional file 6: Table S5A. VIGA annotations of intact prophages. Table S5B. Megablast results of intact prophage metabolic genes (CAZy database). Table S5C. Megablast results of intact prophage type III effectors (Ralsto T3E database). Table S5D. Megablast results of intact prophage virulence factors (Phi-Base database). Table S5E. Predicted functions of abundant intact prophage hypothetical proteins using Structure-based function tool.

Saudi Arabia’s Vision 2030 aims to reform health care across the Kingdom, with health technology assessment being adopted as one tool promising to improve the efficiency with which resources are used. An understanding of the opportunity costs of reimbursement decisions is key to fulfilling this promise and can be used to inform a cost-effectiveness threshold. This paper is the first to provide a range of estimates of this using existing evidence extrapolated to the context...

MALDI-TOF MS spectra, LC-MS/MS datafiles, and Mascot MZID files of modern bone collagen of 18 species of Pleuronectiformes as reference spectra that were used to develop peptide biomarkers for ZooMS (Zooarchaeology by Mass Spectrometry). Details on the samples used can be found in the file "Reference spectra information.csv". Further information on the method and results can be found in the manuscript. The file names contain the type of data file and the species name. MALDI-TOF...

During courtship, male butterflies produce androconial secretions containing male sex pheromones (MSPs) that communicate species identity and affect female choice. MSPs are thus likely candidates as reproductive barriers, yet their role in speciation remains poorly studied. Although Heliconius butterflies are a model system in speciation, their MSPs have not been investigated from a macroevolutionary perspective. We use GC-MS to characterise male androconial secretions in 33 of the 69 species in the Heliconiini tribe. We found...

We present here the Bedmap3 ice thickness, bed and surface elevation standardised CSV data points that are used to create the Bedmap3 gridding products in addition to the previous data releases. The data consists of 50 million points acquired by 17 different data providers in Antarctica. The associated datasets consist of: - Bedmap1 standardised CSV data points: https://doi.org/10.5285/f64815ec-4077-4432-9f55-0ce230f46029 - Bedmap2 standardised CSV data points: https://doi.org/10.5285/2fd95199-365e-4da1-ae26-3b6d48b3e6ac - Bedmap3 statistically-summarised data points (shapefiles): https://doi.org/10.5285/a72a50c6-a829-4e12-9f9a-5a683a1acc4a This work is...

Additional file 4: Table S3. Predicted functions of known proteins using structure-based annotation tool.

Additional file 1. Lists of bacterial and fungal OTUs identified as rhythmic in dawn vs dusk comparisons under 12L12D.