14 Works

Genomic evidence of past and future climate-linked loss in a migratory Arctic fish

Kara K. S. Layton, Paul V. R. Snelgrove, J. Brian Dempson, Tony Kess, Sarah J. Lehnert, Paul Bentzen, Steven J. Duffy, Amber M. Messmer, Ryan R. E. Stanley, Claudio DiBacco, Sarah J. Salisbury, Daniel E. Ruzzante, Cameron M. Nugent, Moira M. Ferguson, Jong S. Leong, Ben F. Koop & Ian R. Bradbury
Despite widespread biodiversity losses, an understanding of how most taxa will respond to future climate change is lacking. Here we integrate genomics and environmental modelling to assess climate change responses in an ecologically and economically important Arctic species. Environmentally associated genomic diversity and machine learning are used to identify highly vulnerable populations of anadromous (migratory) Arctic charr, and we reconstruct estimates of effective population size spanning the twentieth century to identify past climate-associated declines. We...

Zostera marina microsatellite and environmental data

Erin Foster, Jane Watson, Matthew Lemay, Tim Tinker, James Estes, Rebecca Piercey, Lauren Henson, Carol Ritland, Allyson Miscampbell, Linda Nichol, Margot Hessing-Lewis, Anne Salomon & Chris Darimont
Microsatellite data for Zostera marina, sea otter occupancy information, and environmental data from the west coast of British Columbia, Canada.

Kananaskis/Willmore Camera and Landcover Data

Sandra Frey
Anthropogenic landscape change is a leading driver of biodiversity loss. Preceding dramatic changes such as wildlife population declines and range shifts, more subtle responses may signal impending larger-scale change. For example, disturbance-induced shifts to species’ activity patterns may disrupt temporal niche partitioning along the 24-h time axis, compromising community structure via altered competitive interactions. We investigated the impacts of human landscape disturbance on species’ activity patterns and temporal niche partitioning in the Canadian Rocky Mountain...

Noninnocent Role of Na+ Ions in the Binding of the N-Phenyl-2-naphthylammonium Cation as a Ditopic Guest with Cucurbit[7]uril

Suma S Thomas, Hao Tang & Cornelia Bohne
Na+ ions influence the mechanism for the binding of the ditopic guest N-phenyl-2-naphthylammonium cation (Ph-AH+-Np) to cucurbit[7]uril (CB[7]) by facilitating, at increased Na+ concentrations, the formation of a higher-order complex. Binding of the larger naphthyl moiety of Ph-AH+-Np forms the Ph-AH+-Np@CB[7] 1:1 complex (where “@” represents an inclusion complex) at low Na+ ion concentrations (≤5 mM), whereas the inclusion of the smaller phenyl moiety in CB[7] (CB[7]@Ph-AH+-Np) is transient. Ph-AH+-Np@CB[7] is formed by reactions with...

Data from: A synthesis of the prevalence and drivers of non-compliance in marine protected areas

Josephine Iacarella, Georgia Clyde, Brock Bergseth & Natalie Ban
Non-compliance regularly negates the effectiveness of marine protected areas (MPAs) worldwide. Understanding and addressing non-compliance is critical given continued efforts to establish MPAs to meet international milestones (e.g., Aichi targets). We conducted a literature review and meta-analysis to address five key questions and research gaps for MPAs: 1) how is non-compliance best measured? 2) what are common drivers of non-compliance? 3) what is the overall prevalence of non-compliance? 4) how frequently is ecological failure of...

Genotypes for herring samples collected from Chinook salmon gut contents

Eleni Petrou, Joshua Chamberlin, Will Duguid, Russel Barsh, Francis Juanes, Jessica Qualley & Lorenz Hauser
Dynamic prey resources influence foraging opportunities for consumers. In coastal food webs, forage fish abundance and seasonal reproduction mediate foraging opportunities for mobile consumers. Recent declines in Chinook salmon productivity have prompted efforts to determine whether poormarine survival is caused by limited feeding opportunities. To establish the importance of phenological diversity in Pacific herring for Chinook salmon, we used genetic stock identification to assign individual herring collected from the guts of juvenile and adult Chinook...

Inhibition of histone binding by supramolecular hosts

Fraser Hof, Hillary F. Allen, Kevin D. Daze, Takashi Shimbo, Anne Lai, Catherine A. Musselman, Jennifer K. Sims, Paul A. Wade & Tatiana G. Kutateladze
We report a new set of calixarene-based host compounds and show their applicability in characterizing functions of methyllysine-recognizing epigenetic readers. Calixarenes disrupt the association of the PHD finger of CHD4 with a trimethylated, but not an unmodified, histone tail.

Multispecies modelling reveals potential for habitat restoration to re-establish boreal vertebrate community dynamics

Christopher Beirne, Catherine Sun, Erin Tattersall, Joanna Burgar, Jason Fisher & Cole Burton
1. The restoration of habitats degraded by industrial disturbance is essential for achieving conservation objectives in disturbed landscapes. In boreal ecosystems, disturbances from seismic exploration lines and other linear features have adversely affected biodiversity, most notably leading to declines in threatened woodland caribou. Large-scale restoration of disturbed habitats is needed, yet empirical assessments of restoration effectiveness on wildlife communities remain rare. 2. We used 73 camera trap deployments from 2015-2019 and joint species distribution models...

Divergence in life history and behaviour between hybridizing Phymata

David Punzalan
Life history variation plays a central role in evolutionary and ecological processes, and may be especially pertinent to divergence in closely related species. We investigated life history differences in a pair of parapatric species of ambush bugs (Phymata) and a putative hybrid population. Despite the evidence of gene flow among these species, we found clear divergence between these parapatric populations for a suite of juvenile and adult life history traits including components of fitness. The...

Synthesis of New Trisulfonated Calix[4]arenes Functionalized at the Upper Rim, and Their Complexation with the Trimethyllysine Epigenetic Mark

Kevin D. Daze, Manuel C. F. Ma, Florent Pineux & Fraser Hof
A synthetic route to produce a new family of trisulfonated calix[4]arenes bearing a single group, selectively introduced, that lines the binding pocket is reported. Ten examples, including new sulfonamide and biphenyl-substituted hosts, each with additional binding elements, demonstrate the tuning of guest affinities and selectivities. NMR titrations in phosphate-buffered water show that one of the new hosts binds to the modified amino acid trimethyllysine with the highest affinity and selectivity observed to date.

Cross-continental comparison of parasite communities in a wide-ranging carnivore suggests associations with prey diversity and host density

Astrid Stronen, Barbara Molnar, Paolo Ciucci, Chris Darimont, Lorenza Grottoli, Paul Paquet, Tim Sallows, Judit Smits & Heather Bryan
Parasites are integral to ecosystem functioning yet often overlooked. Improved understanding of host-parasite associations is important, particularly for wide-ranging species for which host range shifts and climate change could alter host-parasite interactions and their effects on ecosystem function. Among the most widely distributed mammals with diverse diets, grey wolves (Canis lupus) host parasites that are transmitted among canids and via prey species. Grey wolf-parasite associations may therefore influence the population dynamics and ecological functions of...

Supramolecular hosts that recognize methyllysines and disrupt the interaction between a modified histone tail and its epigenetic reader protein

Kevin D. Daze, Thomas Pinter, Cory S. Beshara, Andreas Ibraheem, Samuel A. Minaker, Manuel C. F. Ma, Rebecca J. M. Courtemanche, Robert E. Campbell & Fraser Hof
Post-translational modifications of proteins (including phosphorylation, acetylation and methylation, among others) frequently carry out their biological functions by serving as ‘on’ switches for protein–protein interactions. As highly localized and perfectly defined hot-spots for protein–protein binding, th

Host–guest interaction of coumarin-derivative dyes and cucurbit[7]uril: leading to the formation of supramolecular ternary complexes with mercuric ions

Margarita E. Aliaga, Luis García-Río, Márcia Pessêgo, Rodrigo Montecinos, Denis Fuentealba, Iván Uribe, Manuel Martín-Pastor & Olimpo García-Beltrán
The interaction between the studied coumarin derivatives-cucurbit[7]uril complexes and mercuric ions displays a positive cooperative effect relative to the dyes alone.

Guest Binding Dynamics with Cucurbit[7]uril in the Presence of Cations

Hao Tang, Denis Fuentealba, Young Ho Ko, Narayanan Selvapalam, Kimoon Kim & Cornelia Bohne
The binding dynamics of R-(+)-2-naphthyl-1-ethylammonium cation (NpH+) with cucurbit[7]uril (CB[7]) was investigated. Competitive binding with Na+ or H3O+ cations enabled the reaction to be slowed down sufficiently for the kinetics to be studied by fluorescence stopped-flow experiments. The binding of two Na+ cations to CB[7], i.e., CB[7]·Na+ (K01 = 130 ± 10 M–1) and Na+·CB[7]·Na+ (K02 = 21 ± 2 M–1), was derived from the analysis of binding isotherms and the kinetic studies. NpH+ binds...

Registration Year

  • 2021

Resource Types

  • Dataset


  • University of Victoria
  • Fisheries and Oceans Canada
  • Department of Physical and Technical Sciences
  • University of British Columbia
  • University of Washington
  • National Institute of Environmental Health Sciences
  • University of Neuchâtel
  • Facultad Latinoamericana de Ciencias Sociales
  • Institute for Basic Science
  • University of Aberdeen