30 Works

Data from: Distribution and population structure of the anther smut fungus Microbotryum silenes-acaulis parasitizing an arctic-alpine plant

Britta Bueker, Chris Eberlein, Pierre Gladieux, Angela Schaefer, Alodie Snirc, Dominic Bennett, Dominik Begerow, Michael Hood, Tatiana Giraud & Dominic J. Bennett
Cold-adapted organisms with current arctic-alpine distributions have persisted during the last glaciation in multiple ice-free refugia, leaving footprints in their population structure that contrast with temperate plants and animals. However, pathogens that live within hosts having arctic-alpine distributions have been little studied. Here, we therefore investigated the geographical range and population structure of a fungus parasitizing an arctic-alpine plant. A total of 1437 herbarium specimens of the plant Silene acaulis were examined, and the anther...

Association of gray matter atrophy patterns with clinical phenotype and progression in multiple sclerosis

Maria A Rocca, Paola Valsasina, Alessandro Meani, Claudio Gobbi, Chiara Zecca, Alex Rovira, Jaume Sastre-Garriga, Hugh Kearney, Olga Ciccarelli, Lucy Matthews, Jacqueline Palace, Antonio Gallo, Alvino Bisecco, Carsten Lukas, Barbara Bellenberg, Frederik Barkhof, Hugo Vrenken, Paolo Preziosa & Massimo Filippi
Objectives. Grey matter (GM) involvement is clinically relevant in multiple sclerosis (MS). Using source-based morphometry (SBM), we characterized GM atrophy and its 1-year evolution across different MS phenotypes. Methods. Clinical and MRI data were obtained at 8 European sites from 170 healthy controls (HCs) and 398 MS patients (34 clinically isolated syndromes [CIS], 226 relapsing-remitting [RR], 95 secondary progressive [SP] and 43 primary progressive [PP] MS). Fifty-seven HC and 144 MS underwent 1-year follow-up. Baseline...

Repositories for taxonomic data: Where we are and what is missing

Aurélien Miralles, Teddy Bruy, Katherine Wolcott, Mark Scherz, Dominik Begerow, Bank Beszteri, Michael Bonkowski, Janine Felden, Birgit Gemeinholzer, Frank Glaw, Frank Oliver Glöckner, Oliver Hawlitschek, Ivaylo Kostadinov, Tim Nattkemper, Christian Printzen, Jasmin Renz, Nataliya Rybalka, Marc Stadler, Tanja Weibulat, Thomas Wilke, Susanne Renner & Miguel Vences
Natural history collections are leading successful large-scale projects of specimen digitization (images, metadata, DNA barcodes), transforming taxonomy into a big data science. Yet, little effort has been directed towards safeguarding and subsequently mobilizing the considerable amount of original data generated during the process of naming 15–20,000 species every year. From the perspective of alpha-taxonomists, we provide a review of the properties and diversity of taxonomic data, assess their volume and use, and establish criteria for...

Data from: Evolutionary–phylogenetic pathway of the Cretaceous ammonite genus Aegocrioceras and its relationship to Juddiceras spp. and Crioceratites spp.

Manuel F. G. Weinkauf, René Hoffmann & Kurt Wiedenroth
The systematics of ammonoids are complicated by their large degree of intra-specific variation, which complicates a stable validation of species. Aegocrioceras is a heteromorph ammonite from the Lower Saxony Basin in the Hauterivian Boreal, and a prime example of a genus with an unstable internal systematic and external relationship to other ammonoids. Here, we use quantitative morphometrics on Aegocrioceras species from an assemblage collected in the clay pit Resse (north-west Germany) to evaluate the systematics...

An environmental DNA metabarcoding approach versus a visual survey for reefs of Koh Pha‐ngan in Thailand

Fabian Gösser, Maximilian Schweinsberg, Pierre Mittelbach, Eike Schoenig & Ralph Tollrian
Information on diversity indices and abundance of individual species is crucial for the assessment of ecosystem health, especially for endangered ecosystems such as coral reefs. The application of environmental DNA (eDNA) to monitor coral biodiversity is, however, just beginning to come into focus for marine biologists. In this study, an eDNA metabarcoding approach of seawater samples in three different reefs on Koh Pha-ngan, Thailand, was compared with simultaneously collected visual census data. In addition, differences...

Separable gain control of ongoing and evoked activity in the visual cortex by serotonergic input

Zohre Azimi, Ruxandra Barzan, Katharina Spoida, Tatjana Surdin, Patric Wollenweber, Melanie D. Mark, Stefan Herlitze & Dirk Jancke
Controlling gain of cortical activity is essential to modulate weights between internal ongoing communication and external sensory drive. Here, we show that serotonergic input has separable suppressive effects on the gain of ongoing and evoked visual activity. We combined optogenetic stimulation of the dorsal raphe nucleus (DRN) with wide-field calcium imaging, extracellular recordings, and iontophoresis of serotonin (5-HT) receptor antagonists in the mouse primary visual cortex. 5-HT1A receptors promote divisive suppression of spontaneous activity, while...

Data from: Biocultural approaches to sustainability: a systematic review of the scientific literature

Jan Hanspach, L. Jamila Haider, Elisa Oteris-Rozas, Anton Stahl Olafsson, Natalie Gulsrud, Chris Raymond, Mario Torralba, Berta Martín-López, Claudia Bieling, María García Martín, Christian Albert, Thomas Beery, Nora Fagerholm, Isabel Díaz-Reviriego, Annika Drews-Shambroom & Tobias Plieninger
Current sustainability challenges demand approaches that acknowledge a plurality of human-nature interactions and worldviews, for which biocultural approaches are considered appropriate and timely. This systematic review analyses the application of biocultural approaches to sustainability in scientific journal articles published between 1990 and 2018 through a mixed methods approach combining qualitative content analysis and quantitative multivariate methods. The study identifies seven distinct biocultural lenses, i.e. different ways of understanding and applying biocultural approaches, which to different...

Data from: Metabolites of n-Butylparaben and iso-Butylparaben exhibit estrogenic properties in MCF-7 and T47D human breast cancer cell lines

Thomas L. Gonzalez, Rebecca K. Moos, Christina L. Gercsh, Michael D. Johnson, Rudy J. Richardson, Holger M. Koch, James M. Rae & Christina L Gersch
Two oxidized metabolites of n-butylparaben (BuP) and iso-butylparaben (IsoBuP) discovered in human urine samples exhibit structural similarity to endogenous estrogens. We hypothesized that these metabolites bind to the human estrogen receptor (ER) and promote estrogen signaling. We tested this using models of ER-mediated cellular proliferation. The estrogenic properties of 3-hydroxy n-butyl 4-hydroxybenzoate (3OH) and 2-hydroxy iso-butyl 4-hydroxybenzoate (2OH) were determined using the ER-positive, estrogen-dependent human breast cancer cell lines MCF-7, and T47D. The 3OH metabolite...

Transcriptional response of mushrooms to artificial sun exposure

Franz-Sebastian Krah, Jaqueline Hess, Florian Hennicke, Ritwika Kar & Claus Bässler
Climate change causes increased tree mortality leading to canopy loss and thus sun-exposed forest floors. Sun exposure creates extreme temperatures and radiation, with potentially more drastic effects on forest organisms than the current increase in mean temperature. Such conditions might potentially negatively affect the maturation of mushrooms of forest fungi. A failure of reaching maturation would mean no sexual spore release and, thus, entail a loss of genetic diversity. However, we currently have a limited...

ISIMIP3b water abstraction input data

Yoshihide Wada, Martina Flörke, Naota Hanasaki, Hannes Müller Schmied, Simon N. Gosling & Jacob Schewe
This data is based on ISIMIP2a varsoc simulations for 1901-2005, and on RCP6.0 simulations from the Water Futures and Solutions project (Wada et al., 2016) for after 2005. Years before 1901 have been filled with the value for the year 1901.


Bjoern Samans, Marta Rossello Chornet, Araceli Rossello Chornet, Janine Jung, Konstantin Schildknecht, Laura Lozza, Lourdes Alos Zaragoza, Javier Hernández Laforet, Nina Babel & Sven Olek
We analysed whole blood and nasopharyngeal swabs from COVID-19 patients in two different cohorts collected at hospitals in Germany (Bochum) and Spain (Valencia) by epigenetic immune cell quantification using qPCR assays (demethyl-specific). The aim was to investigate the prognostic potential of this approach to identify patients with higher risk for a poor outcome. Also, we compared epigenetic data of patients with those of healthy donors.
Dataset includes Cp (crossing-point) values, cell specific plasmid units...

Data from: Isolation and characterization of nine polymorphic microsatellite markers for the deep-sea shrimp Nematocarcinus lanceopes (Crustacea: Decapoda: Caridea)

Johannes Dambach, Michael J. Raupach, Christoph Mayer, Julia Schwarzer & Florian Leese
BACKGROUND: The shrimp Nematocarcinus lanceopes Bate, 1888 is found in the deep sea around Antarctica and sub-Antarctic islands. Previous studies on mitochondrial data and species distribution models provided evidence for a homogenous circum-Antarctic population of N. lanceopes. However, to analyze the fine-scale population genetic structure and to examine influences of abiotic environmental conditions on population composition and genetic diversity, a set of fast evolving nuclear microsatellite markers is required. FINDINGS: We report the isolation and...

Data from: Phylogeographic analysis of Ligia oceanica (Crustacea: Isopoda) reveals two deep divergent mitochondrial lineages

Michael Raupach, Olaf Bininda-Emonds, Thomas Knebelsberger, Silke Laakmann, Jobst Pfaender & Florian Leese
Isopods of the species Ligia oceanica are typical inhabitants of the rocky intertidal of the northern European coastline. The aim of this study was to assess the genetic structure of this species using mitochondrial and nuclear sequence data. We analysed partial mitochondrial cytochrome c oxidase subunit I (CO1) and 16S rRNA gene sequence data of 161 specimens collected from ten sites ranging from Spain to Norway. For selected specimens, we also sequenced the hypervariable V7...

Data from: The flashlight fish Anomalops katoptron uses bioluminescent light to detect prey in the dark

Jens Hellinger, Peter Jägers, Marcel Donner, Franziska Sutt, Melanie D. Mark, Budiono Senen, Ralf Tollrian, Stefan Herlitze & Ralph Tollrian
Bioluminescence is a fascinating phenomenon occurring in numerous animal taxa in the ocean. The reef dwelling splitfin flashlight fish (Anomalops katoptron) can be found in large schools during moonless nights in the shallow water of coral reefs and in the open surrounding water. Anomalops katoptron produce striking blink patterns with symbiotic bacteria in their sub-ocular light organs. We examined the blink frequency in A. katoptron under various laboratory conditions. During the night A. katoptron swims...

Data from: Humans recognize emotional arousal in vocalizations across all classes of terrestrial vertebrates: evidence for acoustic universals

Piera Filippi, Jenna V. Congdon, John Hoang, Daniel Liu Bowling, Stephan A. Reber, Andrius Pašukonis, Marisa Hoeschele, Sebastian Ocklenburg, Bart De Boer, Christopher B. Sturdy, Albert Newen & Onur Gunturkun
Writing over a century ago, Darwin hypothesized that vocal expression of emotion dates back to our earliest terrestrial ancestors. If this hypothesis is true, we should expect to find cross-species acoustic universals in emotional vocalizations. Studies suggest that acoustic attributes of aroused vocalizations are shared across many mammalian species, and that humans can use these attributes to infer emotional content. But do these acoustic attributes extend to non-mammalian vertebrates? In this study, we asked human...

Data from: Convergent evolution in Arabidopsis halleri and Arabidopsis arenosa on calamine metalliferous soils

Veronica Preite, Christian Sailer, Lara Syllwasschy, Sian Bray, Hassan Ahmadi, Ute Krämer & Levi Yant
It is a plausible hypothesis that parallel adaptation events to the same environmental challenge should result in genetic changes of similar or identical effects, depending on the underlying fitness landscapes. However, systematic testing of this is scarce. Here we examine this hypothesis in two closely related plant species, Arabidopsis halleri and Arabidopsis arenosa, which co-occur at two calamine metalliferous (M) sites harbouring toxic levels of the heavy metals zinc and cadmium. We conduct individual genome...

Data from: Statistical comparison of trait-dependent biogeographical models indicates that Podocarpaceae dispersal is influenced by both seed cone traits and geographical distance

Kristina Vanessa Klaus & Nicholas Joseph Matzke
The ability of lineages to disperse long distances over evolutionary timescales may be influenced by the gain or loss of traits adapted to enhance local, ecological dispersal. For example, some species in the southern conifer sister families Podocarpaceae and Araucariaceae have fleshy cones that encourage bird dispersal, but it is unknown how this trait has influenced the clade’s historical biogeography, or its importance compared to other predictors of dispersal such as the geographic distance between...

ISIMIP3a water abstraction input data

Yoshihide Wada, Martina Flörke, Naota Hanasaki, Hannes Müller Schmied, Simon N. Gosling & Jacob Schewe
The Inter-Sectoral Impact Model Intercomparison Project (ISIMIP) provides a framework for the collation of a consistent set of climate impact data across sectors and scales. It also provides a unique opportunity for considering interactions between climate change impacts across sectors through consistent scenarios.
The ISIMIP3a part of the third simulation round is dedicated to i) impact model evaluation and improvement and ii) detection and attribution of observed impacts according to the framework of IPCC AR5 Working...

Back-Side SEM Images and Respective Modified GDSII Chip Designs

Endres Puschner, Thorben Moos, Steffen Becker, Christian Kison, Amir Moradi & Christof Paar
This data set consists of backside scanning electron microscope (SEM) images of four different CMOS integrated circuits (90nm, 65nm, 40nm and 28nm technologies) recorded for this study. The images are tiled with a 10% overlap and arranged in a grid according to their respective file names (Tile_001-YYY-XXX-[...].tif). More precise coordinates generated by stitching can be found in the file "stitching.zip" which is included in the data set, as well as in the corresponding GitHub repository....

The evolution of sexual signaling is linked to odorant receptor tuning in perfume-collecting orchid bees

Philipp Brand, Ismael A. Hinojosa-Diaz, Ricardo Ayala, Michael Daigle, Carmen L. Yurrita Obiols, Thomas Eltz & Santiago Ramirez
Sexual signaling is an important reproductive barrier known to evolve early during the formation of new species, but the genetic mechanisms that facilitate the divergence of sexual signals remain elusive. Here we isolate a gene linked to the rapid evolution of a signaling trait in a pair of nascent neotropical orchid bee lineages, Euglossa dilemma and E. viridissima. Male orchid bees acquire chemical compounds from their environment to concoct species-specific perfumes to later expose during...

Data from: Neurons in primate visual cortex alternate between responses to multiple stimuli in their receptive field

Kang Li, Vladislav Kozyrev, Søren Kyllingsbæk, Stefan Treue, Susanne Ditlevsen & Claus Bundesen
A fundamental question concerning representation of the visual world in our brain is how a cortical cell responds when presented with more than a single stimulus. We find supportive evidence that most cells presented with a pair of stimuli respond predominantly to one stimulus at a time, rather than a weighted average response. Traditionally, the firing rate is assumed to be a weighted average of the firing rates to the individual stimuli (response-averaging model) (Bundesen...

Working memory capacity of crows and monkeys arises from similar neuronal computations

Lukas Hahn, Dmitry Balakhonov & Jonas Rose
Complex cognition relies on flexible working memory, which is severely limited in its capacity. The neuronal computations underlying these capacity limits have been extensively studied in humans and in monkeys, resulting in competing theoretical models. We probed the working memory capacity of crows (Corvus corone) in a change detection task, developed for monkeys (Macaca mulatta), while we performed extracellular recordings of the prefrontal-like area nidopallium caudolaterale. We found that neuronal encoding and maintenance of information...

Taking a walk through time: aversive memory re-experiencing may be linked to spatio-temporal distance

Thomas Meyer, Janna Nelson & Nexhmedin Morina
Individuals with posttraumatic stress disorder (PTSD) often report intrusive memories that appear to lack the appropriate spatio-temporal context. We examined whether focusing on the spatio-temporal context of aversive autobiographical memories reduces negative emotions, appraisals, and re-experiencing symptoms. We recruited 109 healthy adults and had them rate emotionality, vividness, and re-experiencing of an aversive autobiographical memory. Furthermore, we assessed automatic associations of idiosyncratic memory triggers with the concepts ‘past’ vs. ‘now’, and self-reported sense of memory...

Data from: Integrating 2D and 3D shell morphology to disentangle the palaeobiology of ammonoids: a virtual approach

René Hoffmann, Robert Evan Lemanis, Janina Falkenberg, Steffen Schneider, Hendrik Wesendonk & Stefan Zachow
Based on data derived from computed tomography, we demonstrate that integrating 2D and 3D morphological data from ammonoid shells represents an important new approach for investigating the palaeobiology of ammonoids. Characterization of ammonite morphology has long been constrained to 2D data, with only a few studies collecting ontogenetic data in 180° steps. Here we combine this traditional approach with 3D data collected from high-resolution nano-computed tomography. Ontogenetic morphological data on the hollow shell of a...

Data from: Calcium imaging with genetically encoded sensor Case12: facile analysis of α7/α9 nAChR mutants

Irina Shelukhina, Ekaterina Spirova, Denis Kudryavtsev, Lucy Ojomoko, Markus Werner, Christoph Methfessel, Michael Hollmann & Victor Tsetlin
Elucidation of the structural basis of pharmacological differences for highly homologous α7 and α9 nicotinic acetylcholine receptors (nAChRs) may shed light on their involvement in different physiological functions and diseases. Combination of site-directed mutagenesis and electrophysiology is a powerful tool to pinpoint the key amino-acid residues in the receptor ligand-binding site, but for α7 and α9 nAChRs it is complicated by their poor expression and fast desensitization. Here, we probed the ligand-binding properties of α7/α9...

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  • Ruhr University Bochum
  • Potsdam Institute for Climate Impact Research
  • University of Münster
  • Zoological Research Museum Alexander Koenig
  • University of Göttingen
  • University of Copenhagen
  • Heidelberg University
  • University of Vienna
  • Senckenberg am Meer
  • Freie Universität Berlin