4 Works

Data from: Land-use type and intensity differentially filter traits in above- and belowground arthropod communities

Klaus Birkhofer, Martin M. Gossner, Tim Diekötter, Claudia Drees, Olga Ferlian, Mark Maraun, Stefan Scheu, Wolfgang W. Weisser, Volkmar Wolters, Susanne Wurst, Andrey S. Zaitsev & Henrik G. Smith
1. Along with the global decline of species richness goes a loss of ecological traits. Associated biotic homogenization of animal communities and narrowing of trait diversity threaten ecosystem functioning and human well-being. High management intensity is regarded as an important ecological filter, eliminating species that lack suitable adaptations. Belowground arthropods are assumed to be less sensitive to such effects than aboveground arthropods. 2. Here, we compared the impact of management intensity between (grassland vs. forest)...

Data from: Olive oil bioactives protect pigs against experimentally-induced chronic inflammation independently of alterations in gut microbiota

Martin Liehr, Alessandro Mereu, Jose Javier Pastor, Jose Carlos Quintela, Stefanie Staats, Gerald Rimbach & Ignacio Rodolfo Ipharraguerre
Subclinical chronic inflammation (SCI) is associated with impaired animal growth. Previous work has demonstrated that olive-derived plant bioactives exhibit anti-inflammatory properties that could possibly counteract the growth-depressing effects of SCI. To test this hypothesis and define the underlying mechanism, we conducted a 30-day study in which piglets fed an olive-oil bioactive extract (OBE) and their control counterparts (C+) were injected repeatedly during the last 10 days of the study with increasing doses of Escherichia coli...

Data from: Transcriptomic alterations during ageing reflect the shift from cancer to degenerative diseases in the elderly

Peer Aramillo Irizar, Sascha Schäuble, Daniela Esser, Marco Groth, Christiane Frahm, Steffen Priebe, Mario Baumgart, Nils Hartmann, Shiva Marthandan, Uwe Menzel, Jule Müller, Silvio Schmidt, Volker Ast, Amke Caliebe, Rainer König, Michael Krawczak, Michael Ristow, Stefan Schuster, Alessandro Cellerino, Stephan Diekmann, Christoph Englert, Peter Hemmerich, Jürgen Sühnel, Reinhard Guthke, Otto W. Witte … & Christoph Kaleta
Disease epidemiology during ageing shows a transition from cancer to degenerative chronic disorders as dominant contributors to mortality in the old. Nevertheless, it has remained unclear to what extent molecular signatures of ageing reflect this phenomenon. Here we report on the identification of a conserved transcriptomic signature of ageing based on gene expression data from four vertebrate species across four tissues. We find that ageing-associated transcriptomic changes follow trajectories similar to the transcriptional alterations observed...

Data from: Adhesion forces and mechanics in mannose-mediated acanthamoeba interactions

Steven Huth, Julia F. Reverey, Matthias Leippe & Christine Selhuber‐Unkel
The human pathogenic amoeba Acanthamoeba castellanii (A. castellanii) causes severe diseases, including acanthamoeba keratitis and encephalitis. Pathogenicity arises from the killing of target-cells by an extracellular killing mechanism, where the crucial first step is the formation of a close contact between A. castellanii and the target-cell. This process is mediated by the glycocalix of the target-cell and mannose has been identified as key mediator. The aim of the present study was to carry out a...

Registration Year

  • 2017
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Affiliations

  • Kiel University
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  • University of Hamburg
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  • Lund University
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  • German Center for Integrative Biodiversity Research
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  • University of Göttingen
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  • Technical University Munich
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  • Brandenburg University of Technology
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  • University of Giessen
    1
  • Jena University Hospital
    1
  • Leipzig University
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