4 Works

Data from: Fine-scale spatial and temporal population genetics of Aedes japonicus, a new US mosquito, reveal multiple introductions

Dina Fonseca, Andrea Widdel, Sven-Erik Spichiger, Michael Hutchinson & Laura Kramer
The newly introduced mosquito Aedes japonicus has expanded from its original range in Northeastern Asia to twenty-two US states (including Hawaii) plus Canada and northern Europe. Our objectives were to test an earlier hypothesis of multiple introductions of this species to the Northeastern US, and evaluate putative temporal changes in genetic makeup. Using a panel of seven microsatellite loci, we confirmed the existence of two abundant genetic forms in specimens originally collected in 1999-2000 (FST...

Data from: Mosquito saliva increases endothelial permeability in the skin, immune cell migration, and dengue pathogenesis during antibody-dependent enhancement

Michael A. Schmid, Dustin R. Glasner, Sanjana Shah, Daniela Michlmayr, Laura D. Kramer, & Eva Harris
Dengue remains the most prevalent arthropod-borne viral disease in humans. While probing for blood vessels, Aedes aegypti and Ae. albopictus mosquitoes transmit the four serotypes of dengue virus (DENV1-4) by injecting virus-containing saliva into the skin. Even though arthropod saliva is known to facilitate transmission and modulate host responses to other pathogens, the full impact of mosquito saliva on dengue pathogenesis is still not well understood. Inoculating mice lacking the interferon-α/β receptor intradermally with DENV...

Data from: A phylogenomic approach to clarifying the relationship of Mesodinium within the Ciliophora: a case study in the complexity of mixed-species transcriptome analyses

Erica Lasek-Nesselquist & Matthew D. Johnson
Recent high-throughput sequencing endeavors have yielded multi-gene/protein phylogenies that confidently resolve several inter- and intra-class relationships within the phylum Ciliophora. We leverage the massive sequencing efforts from the Marine Microbial Eukaryote Transcriptome Sequencing Project, other SRA submissions, and available genome data with our own sequencing efforts to determine the phylogenetic position of Mesodinium and to generate the most taxonomically-rich phylogenomic ciliate tree to date. Regardless of the data mining strategy, the multi-protein dataset, or the...

Data from: A phylogenomic approach to clarifying the relationship of Mesodinium within the Ciliophora: a case study in the complexity of mixed-species transcriptome analyses

Erica Lasek-Nesselquist & Matthew D. Johnson
Recent high-throughput sequencing endeavors have yielded multi-gene/protein phylogenies that confidently resolve several inter- and intra-class relationships within the phylum Ciliophora. We leverage the massive sequencing efforts from the Marine Microbial Eukaryote Transcriptome Sequencing Project, other SRA submissions, and available genome data with our own sequencing efforts to determine the phylogenetic position of Mesodinium and to generate the most taxonomically-rich phylogenomic ciliate tree to date. Regardless of the data mining strategy, the multi-protein dataset, or the...

Registration Year

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Affiliations

  • Wadsworth Center
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  • Woods Hole Oceanographic Institution
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  • Pennsylvania Department of Environmental Protection
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  • University of California, Berkeley
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  • Rutgers University
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