25 Works
LINC00857 regulated by ZNF460 enhances the expression of CLDN12 by sponging miR-150-5p and recruiting SRSF1 for alternative splicing to promote epithelial-mesenchymal transformation of pancreatic adenocarcinoma cells
Yong Zhang, Yuan Fang, Lijie Ma, Jing Xu, Chentao Lv, Li Deng & Guanghui Zhu
Recent research unveiled that LINC00857 plays a regulatory role in multiple human cancers, such as lung adenocarcinoma and gastric cancer. Nevertheless, the function of LINC00857 in pancreatic adenocarcinoma (PAAD) remains unclear. This study concentrates on LINC00857 to discuss the relevant molecular mechanism of this gene in PAAD. Quantitative reverse transcription polymerase chain reaction (RT-qPCR) and western blot were implemented for measuring the expressions of RNAs and proteins. Wound healing and Transwell assays were used to...
Additional file 4 of De novo full length transcriptome analysis and gene expression profiling to identify genes involved in phenylethanol glycosides biosynthesis in Cistanche tubulosa
Lei Hou, Guanghui Li, Qingliang Chen, JinJin Zhao, Jiaowen Pan, Ruxia Lin, Xiujin Zhu, Pengfei Wang & Xingjun Wang
Additional file 4: Supplementary Table S2. Coding ability prediction results of the full-length transcripts.
Additional file 6 of De novo full length transcriptome analysis and gene expression profiling to identify genes involved in phenylethanol glycosides biosynthesis in Cistanche tubulosa
Lei Hou, Guanghui Li, Qingliang Chen, JinJin Zhao, Jiaowen Pan, Ruxia Lin, Xiujin Zhu, Pengfei Wang & Xingjun Wang
Additional file 6: Supplementary Table S4. Differential expression of genes involved in PS, PM and TM pathways.
Additional file 8 of De novo full length transcriptome analysis and gene expression profiling to identify genes involved in phenylethanol glycosides biosynthesis in Cistanche tubulosa
Lei Hou, Guanghui Li, Qingliang Chen, JinJin Zhao, Jiaowen Pan, Ruxia Lin, Xiujin Zhu, Pengfei Wang & Xingjun Wang
Additional file 8: Supplementary Table S6. KEGG pathways of DEGs between HS2 and YS1.
Additional file 9 of De novo full length transcriptome analysis and gene expression profiling to identify genes involved in phenylethanol glycosides biosynthesis in Cistanche tubulosa
Lei Hou, Guanghui Li, Qingliang Chen, JinJin Zhao, Jiaowen Pan, Ruxia Lin, Xiujin Zhu, Pengfei Wang & Xingjun Wang
Additional file 9: Supplementary Table S7. Primers for qRT-PCR analysis.
Chloroquine treatment induces secretion of autophagy-related proteins and inclusion of Atg8-family proteins in distinct extracellular vesicle populations
Jing Xu, Kevin C Yang, Nancy Erro Go, Shane Colborne, Cally J Ho, Elham Hosseini-Beheshti, Alf H Lystad, Anne Simonsen, Emma Tomlinson Guns, Gregg B Morin & Sharon M Gorski
Chloroquine (CQ), a lysosomotropic agent, is commonly used to inhibit lysosomal degradation and macroautophagy/autophagy. Here we investigated the cell-extrinsic effects of CQ on secretion. We showed that lysosomal and autophagy inhibition by CQ altered the secretome, and induced the release of Atg8 orthologs and autophagy receptors. Atg8-family proteins, in particular, were secreted inside small extracellular vesicles (sEVs) in a lipidation-dependent manner. CQ treatment enhanced the release of Atg8-family proteins inside sEVs. Using full-length ATG16L1 and...
Additional file 10 of De novo full length transcriptome analysis and gene expression profiling to identify genes involved in phenylethanol glycosides biosynthesis in Cistanche tubulosa
Lei Hou, Guanghui Li, Qingliang Chen, JinJin Zhao, Jiaowen Pan, Ruxia Lin, Xiujin Zhu, Pengfei Wang & Xingjun Wang
Additional file 10: Supplementary Table S8. Differential expression of transcription factors genes.
Additional file 6 of De novo full length transcriptome analysis and gene expression profiling to identify genes involved in phenylethanol glycosides biosynthesis in Cistanche tubulosa
Lei Hou, Guanghui Li, Qingliang Chen, JinJin Zhao, Jiaowen Pan, Ruxia Lin, Xiujin Zhu, Pengfei Wang & Xingjun Wang
Additional file 6: Supplementary Table S4. Differential expression of genes involved in PS, PM and TM pathways.
Additional file 7 of De novo full length transcriptome analysis and gene expression profiling to identify genes involved in phenylethanol glycosides biosynthesis in Cistanche tubulosa
Lei Hou, Guanghui Li, Qingliang Chen, JinJin Zhao, Jiaowen Pan, Ruxia Lin, Xiujin Zhu, Pengfei Wang & Xingjun Wang
Additional file 7: Supplementary Table S5. Differentially expressed genes between HS2 and YS1.
Additional file 7 of De novo full length transcriptome analysis and gene expression profiling to identify genes involved in phenylethanol glycosides biosynthesis in Cistanche tubulosa
Lei Hou, Guanghui Li, Qingliang Chen, JinJin Zhao, Jiaowen Pan, Ruxia Lin, Xiujin Zhu, Pengfei Wang & Xingjun Wang
Additional file 7: Supplementary Table S5. Differentially expressed genes between HS2 and YS1.
Additional file 10 of De novo full length transcriptome analysis and gene expression profiling to identify genes involved in phenylethanol glycosides biosynthesis in Cistanche tubulosa
Lei Hou, Guanghui Li, Qingliang Chen, JinJin Zhao, Jiaowen Pan, Ruxia Lin, Xiujin Zhu, Pengfei Wang & Xingjun Wang
Additional file 10: Supplementary Table S8. Differential expression of transcription factors genes.
RESEARCH ON WIND PRESSURE DISTRIBUTION OF PLASTIC GREENHOUSES IN VALLEY TOPOGRAPHY
Jing Xu, Guifeng He, Xiaoying Ren & Zhikang Hu
ABSTRACT As the wind pressure distribution on plastic greenhouses in valley areas is different from that of greenhouses on plains, it is necessary to find out the variation trend of the wind pressure coefficient on greenhouses in the valley areas. Based on the ‘Realizable k-e turbulence’ model, the wind pressure characteristics on plastic greenhouses located in valley and plain areas are studied by using the verified numerical simulation method. The wind pressures on greenhouses and...
Additional file 2 of Cross-watershed distribution pattern challenging the elimination of Oncomelania hupensis, the intermediate host of Schistosoma japonicum, in Sichuan province, China
Shen Chen, Ding Lu, Lei Duan, Ben Ma, Chao Lv, Yin-long Li, Shen-ning Lu, Lan-hua Li, Liang Xu, Zi-song Wu, Shang Xia, Jing Xu, Yang Liu & Shan Lv
Additional file 2: Dataset S1. The 130 unique cox1 haplotypes of Oncomelania hupensis from this study including two outgroups
LINC00857 regulated by ZNF460 enhances the expression of CLDN12 by sponging miR-150-5p and recruiting SRSF1 for alternative splicing to promote epithelial-mesenchymal transformation of pancreatic adenocarcinoma cells
Yong Zhang, Yuan Fang, Lijie Ma, Jing Xu, Chentao Lv, Li Deng & Guanghui Zhu
Recent research unveiled that LINC00857 plays a regulatory role in multiple human cancers, such as lung adenocarcinoma and gastric cancer. Nevertheless, the function of LINC00857 in pancreatic adenocarcinoma (PAAD) remains unclear. This study concentrates on LINC00857 to discuss the relevant molecular mechanism of this gene in PAAD. Quantitative reverse transcription polymerase chain reaction (RT-qPCR) and western blot were implemented for measuring the expressions of RNAs and proteins. Wound healing and Transwell assays were used to...
Additional file 2 of Cross-watershed distribution pattern challenging the elimination of Oncomelania hupensis, the intermediate host of Schistosoma japonicum, in Sichuan province, China
Shen Chen, Ding Lu, Lei Duan, Ben Ma, Chao Lv, Yin-long Li, Shen-ning Lu, Lan-hua Li, Liang Xu, Zi-song Wu, Shang Xia, Jing Xu, Yang Liu & Shan Lv
Additional file 2: Dataset S1. The 130 unique cox1 haplotypes of Oncomelania hupensis from this study including two outgroups
Additional file 3 of De novo full length transcriptome analysis and gene expression profiling to identify genes involved in phenylethanol glycosides biosynthesis in Cistanche tubulosa
Lei Hou, Guanghui Li, Qingliang Chen, JinJin Zhao, Jiaowen Pan, Ruxia Lin, Xiujin Zhu, Pengfei Wang & Xingjun Wang
Additional file 3: Supplementary Table S1. Seven databases showed the annotation results of the full-length transcripts.
Additional file 8 of De novo full length transcriptome analysis and gene expression profiling to identify genes involved in phenylethanol glycosides biosynthesis in Cistanche tubulosa
Lei Hou, Guanghui Li, Qingliang Chen, JinJin Zhao, Jiaowen Pan, Ruxia Lin, Xiujin Zhu, Pengfei Wang & Xingjun Wang
Additional file 8: Supplementary Table S6. KEGG pathways of DEGs between HS2 and YS1.
Additional file 4 of De novo full length transcriptome analysis and gene expression profiling to identify genes involved in phenylethanol glycosides biosynthesis in Cistanche tubulosa
Lei Hou, Guanghui Li, Qingliang Chen, JinJin Zhao, Jiaowen Pan, Ruxia Lin, Xiujin Zhu, Pengfei Wang & Xingjun Wang
Additional file 4: Supplementary Table S2. Coding ability prediction results of the full-length transcripts.
Additional file 5 of De novo full length transcriptome analysis and gene expression profiling to identify genes involved in phenylethanol glycosides biosynthesis in Cistanche tubulosa
Lei Hou, Guanghui Li, Qingliang Chen, JinJin Zhao, Jiaowen Pan, Ruxia Lin, Xiujin Zhu, Pengfei Wang & Xingjun Wang
Additional file 5: Supplementary Table S3. Transcription factor families and transcription factor genes.
Additional file 9 of De novo full length transcriptome analysis and gene expression profiling to identify genes involved in phenylethanol glycosides biosynthesis in Cistanche tubulosa
Lei Hou, Guanghui Li, Qingliang Chen, JinJin Zhao, Jiaowen Pan, Ruxia Lin, Xiujin Zhu, Pengfei Wang & Xingjun Wang
Additional file 9: Supplementary Table S7. Primers for qRT-PCR analysis.
Chloroquine treatment induces secretion of autophagy-related proteins and inclusion of Atg8-family proteins in distinct extracellular vesicle populations
Jing Xu, Kevin C Yang, Nancy Erro Go, Shane Colborne, Cally J Ho, Elham Hosseini-Beheshti, Alf H Lystad, Anne Simonsen, Emma Tomlinson Guns, Gregg B Morin & Sharon M Gorski
Chloroquine (CQ), a lysosomotropic agent, is commonly used to inhibit lysosomal degradation and macroautophagy/autophagy. Here we investigated the cell-extrinsic effects of CQ on secretion. We showed that lysosomal and autophagy inhibition by CQ altered the secretome, and induced the release of Atg8 orthologs and autophagy receptors. Atg8-family proteins, in particular, were secreted inside small extracellular vesicles (sEVs) in a lipidation-dependent manner. CQ treatment enhanced the release of Atg8-family proteins inside sEVs. Using full-length ATG16L1 and...
Additional file 2 of Cross-watershed distribution pattern challenging the elimination of Oncomelania hupensis, the intermediate host of Schistosoma japonica, in Sichuan province, China
Shen Chen, Ding Lu, Lei Duan, Ben Ma, Chao Lv, Yin-long Li, Shen-ning Lu, Lan-hua Li, Liang Xu, Zi-song Wu, Shang Xia, Jing Xu, Yang Liu & Shan Lv
Additional file 2: Dataset S1. The 130 unique cox1 haplotypes of Oncomelania hupensis from this study including two outgroups
RESEARCH ON WIND PRESSURE DISTRIBUTION OF PLASTIC GREENHOUSES IN VALLEY TOPOGRAPHY
Jing Xu, Guifeng He, Xiaoying Ren & Zhikang Hu
ABSTRACT As the wind pressure distribution on plastic greenhouses in valley areas is different from that of greenhouses on plains, it is necessary to find out the variation trend of the wind pressure coefficient on greenhouses in the valley areas. Based on the ‘Realizable k-e turbulence’ model, the wind pressure characteristics on plastic greenhouses located in valley and plain areas are studied by using the verified numerical simulation method. The wind pressures on greenhouses and...
Additional file 3 of De novo full length transcriptome analysis and gene expression profiling to identify genes involved in phenylethanol glycosides biosynthesis in Cistanche tubulosa
Lei Hou, Guanghui Li, Qingliang Chen, JinJin Zhao, Jiaowen Pan, Ruxia Lin, Xiujin Zhu, Pengfei Wang & Xingjun Wang
Additional file 3: Supplementary Table S1. Seven databases showed the annotation results of the full-length transcripts.
Additional file 5 of De novo full length transcriptome analysis and gene expression profiling to identify genes involved in phenylethanol glycosides biosynthesis in Cistanche tubulosa
Lei Hou, Guanghui Li, Qingliang Chen, JinJin Zhao, Jiaowen Pan, Ruxia Lin, Xiujin Zhu, Pengfei Wang & Xingjun Wang
Additional file 5: Supplementary Table S3. Transcription factor families and transcription factor genes.
Affiliations
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Huangshan University25
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Capital Medical University21
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Shandong University19
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Beijing University of Chinese Medicine18
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Agricultural University of Hebei16
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Shandong Academy of Agricultural Sciences16
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Shanxi Agricultural University12
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Shanghai University of Traditional Chinese Medicine9
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Sun Yat-sen Memorial Hospital9
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Qingdao University9