2 Works

Data from: Genomic islands of speciation separate cichlid ecomorphs in an East African crater lake

Milan Malinsky, Richard J. Challis, Alexandra M. Tyers, Stephan Schiffels, Yohey Terai, Benjamin P. Ngatunga, Eric A. Miska, Richard Durbin, Martin J. Genner & George F. Turner
The genomic causes and effects of divergent ecological selection during speciation are still poorly understood. Here we report the discovery and detailed characterization of early-stage adaptive divergence of two cichlid fish ecomorphs in a small (700 meters in diameter) isolated crater lake in Tanzania. The ecomorphs differ in depth preference, male breeding color, body shape, diet, and trophic morphology. With whole-genome sequences of 146 fish, we identified 98 clearly demarcated genomic “islands” of high differentiation...

Data from: Population genomic datasets describing the post-vaccine evolutionary epidemiology of Streptococcus pneumoniae

Nicholas J. Croucher, Jonathan A. Finkelstein, Steven I. Pelton, Julian Parkhill, Stephen D. Bentley, William P. Hanage & Marc Lipsitch
Streptococcus pneumoniae is common nasopharyngeal commensal bacterium and important human pathogen. Vaccines against a subset of pneumococcal antigenic diversity have reduced rates of disease, without changing the frequency of asymptomatic carriage, through altering the bacterial population structure. These changes can be studied in detail through using genome sequencing to characterise systematically-sampled collections of carried S. pneumoniae. This dataset consists of 616 annotated draft genomes of isolates collected from children during routine visits to primary care...

Registration Year

  • 2015
    2

Resource Types

  • Dataset
    2

Affiliations

  • Wellcome Sanger Institute
    2
  • Bangor University
    1
  • Tanzania Fisheries Research Institute
    1
  • Harvard Medical School
    1
  • Imperial College London
    1
  • University of Bristol
    1
  • Boston University
    1