220 Works

Data from: Hovering in the heat: effects of environmental temperature on heat regulation in foraging hummingbirds

Donald R. Powers, Kathleen M. Langland, Susan M. Wethington, Sean D. Powers, Catherine H. Graham & Bret W. Tobalske
At high temperature (>40 ºC) endotherms experience reduced passive heat dissipation (radiation, conduction, and convection) and increased reliance on evaporative heat loss. High temperatures challenge flying birds due to heat produced by wing muscles. Hummingbirds depend on flight for foraging, yet inhabit hot regions. We used infrared thermography to explore how lower passive heat dissipation during flight impacts body-heat management in broad-billed (Cynanthus latirostris, 3.0g), black-chinned (Archilochus alexandri, 3.0g), Rivoli’s (Eugenes fulgens, 7.5g), and blue-throated...

Investigations of the underlying mechanisms of HIF-1α and CITED2 binding to TAZ1

Wen-Ting Chu, Xiakun Chu & Jin Wang
The TAZ1 domain of CREB binding protein is crucial for transcriptional regulation and recognizes multiple targets. The interactions between TAZ1 and its specific targets are related to the cellular hypoxic negative feedback regulation. Previous experiments reported that one of the TAZ1 targets CITED2 is an efficient competitor of another target HIF-1α. Here by developing the structure-based models of TAZ1 complexes we have uncovered the underlying mechanisms of the competitions between the two intrinsic disordered proteins...

Diversity in lac Operon Regulation among Diverse Escherichia coli Isolates Depends on the Broader Genetic Background but Is Not Explained by Genetic Relatedness

Tim Cooper, Kelly Phillips, Scott Widmann, Jennifer Nguyen, Christian Ray, Gabor Balazsi & Huei-Yi Lai
Transcription of bacterial genes is controlled by the coordinated action of cis- and trans-acting regulators. The activity and mode of action of these regulators can reflect different requirements for gene products in different environments. A well-studied example is the regulatory function that integrates the environmental availability of glucose and lactose to control the Escherichia coli lac operon. Most studies of lac operon regulation have focused on a few closely related strains. To determine the range...

Data from: Estimation of energetic condition in wild baboons using fecal thyroid hormone determination

Laurence R. Gesquiere, Mya Pugh, Susan C. Alberts & A. Catherine Markham
Understanding how environmental and social factors affect reproduction through variation in energetic condition remains understudied in wild animals, in large part because accurately and repeatedly measuring energetic condition in the wild is a challenge. Thyroid hormones (THs), such as triiodothyronine (T3) and thyroxine (T4), have a key role in mitigating metabolic responses to energy intake and expenditure, and therefore are considered important biomarkers of an animal's energetic condition. Recent method development has shown that T3...

Data from: Fruiting phenology is linked to rainfall variability in a tropical rain forest

Amy E. Dunham, Onja H. Razafindratsima, Paul Rakotonirina, Patricia C. Wright. & Patricia C. Wright
As the influence of climate change on tropical forests becomes apparent, more studies are needed to understand how changes in climatic variables like rainfall are likely to affect tree phenology. Using a twelve-year dataset (2005–2016), we studied the impact of seasonal rainfall patterns on the fruiting phenology of 69 tree species in the rain forest of southeastern Madagascar. We found that average annual rainfall in this region has increased by >800mm (23%) during this period...

Data from: Multifactorial processes underlie parallel opsin loss in neotropical bats

Alexa Sadier, Kalina T. J. Davies, Laurel R. Yohe, Kun Yun, Paul Donat, Brandon P. Hedrick, Elizabeth R. Dumont, Liliana M. Davalos, Stephen J. Rossiter & Karen E. Sears
The loss of previously adaptive traits is typically linked to relaxation in selection, yet the molecular steps leading to such repeated losses are rarely known. Molecular studies of loss have tended to focus on gene sequences alone, but overlooking other aspects of protein expression might underestimate phenotypic diversity. Insights based almost solely on opsin gene evolution, for instance, have made mammalian color vision a textbook example of phenotypic loss. We address this gap by investigating...

Differential activation of c-Fos and Egr1 during development of the mouse visual cortex

Alexander Lazutkin, Anna Ivanova, Pavel Rogozin, Grigori Enikolopov & Konstantin Anokhin
Critical periods (CP) in brain development are associated with profound changes in gene expression cascades. Here we examine the expression of the immediate early genes c-Fos and Egr1 at different stages of mouse visual cortex (VC) development. Mice 11, 25, and 50 days of age were maintained under standard light-dark conditions, deprived of light for 5 days, or deprived of light for 5 days and then exposed to light for 90 min. Their brains were...

Supporting Data To: Shark tooth collagen stable isotopes (δ15N and δ13C) as ecological proxies

Oliver Shipley, Gregory Henkes, James Gelsleichter, Clark Morgan, Eric Schneider, Brendan Talwar & Michael Frisk
The isotopic composition of tooth-bound collagen has long been used to reconstruct dietary patterns of animals in extant and paleoecological systems. For sharks that replace teeth rapidly in a conveyor-like system, stable isotopes of tooth collagen (δ13Ctooth & δ15Ntooth) are poorly understood and lacking in ecological context relative to other non-lethally sampled tissues. This tissue holds promise, because shark jaws may preserve isotopic chronologies from which to infer individual-level ecological patterns across a range of...

Using 2D dental geometric morphometrics to identify modern Perognathus and Chaetodipus specimens (Rodentia, Heteromyidae)

Megan R Wyatt, Samantha S B Hopkins & Edward B Davis
The Heteromyidae (pocket mice and kangaroo rats) are a group of extant small rodents abundant in western North America, as well as in fossil assemblages over the last 20 million years. Two genera of heteromyids, Chaetodipus and Perognathus, share similar tooth morphology and teeth are the primary fossil remains. Previous genetic studies show these extant sister genera likely diverged in the middle Miocene (~16 million years ago); however, the Chaetodipus fossil record starts in the...

Structure-from-motion-generated imagery, nest location coordinates and counts for Adelie, chinstrap, gentoo and macaroni penguins on the South Sandwich Islands, from December to February, 2019-2020.

Tom Hart, Sarah Manthorpe, Gemma Clucas & Heather Lynch
This dataset contains penguin survey data and imagery from unmanned aerial vehicles (UAV) across the South Sandwich Islands, from December 2019 to February 2020. It comprises orthotiff images (orthotiffs) and digital elevation models (DEMS) of surveyed sites, geographic penguin colony outlines, nest coordinates for individual species, mixed species' sub-colonies and groups where species-level identification was not possible. Finally, it also includes the total count for these different categories for each individual site, alongside an estimate...

Recombination experiments with inversion heterozygotes

Spencer Koury
Recombination suppression in chromosomal inversion heterozygotes is a well-known but poorly understood phenomenon. Surprisingly, recombination suppression extends far outside of inverted regions where there are no intrinsic barriers to normal chromosome pairing, synapsis, double-strand break formation, or recovery of crossover products. The interference hypothesis of recombination suppression proposes heterozygous inversion breakpoints possess chiasma-like properties such that recombination suppression extends from these breakpoints in a process analogous to crossover interference. This hypothesis is qualitatively consistent with...

Why the long teeth? Morphometric analysis suggests different selective pressures on functional occlusal traits in Plio-Pleistocene African suids

Deming Yang, Asli Pisano, Joan Kolasa, Tea Jashashvili, Job Kibii, Ana Gomez Cano, Laurent Viriot, Frederick Grine & Antoine Souron
Neogene and Pleistocene African suids displayed convergent evolutionary trends in the third molar (M3) morphology, with increasingly elongated and higher crowns through time. While these features can prevent premature loss of masticatory functionality and potentially increase long-term reproductive success, changes in dental occlusal traits such as enamel complexity and thickness can also improve chewing efficiency and increase short-term energetic return. While both long-term and short-term benefits can contribute to the thriving of a lineage, the...

Additional file 2 of Replication stress generates distinctive landscapes of DNA copy number alterations and chromosome scale losses

Nadeem Shaikh, Alice Mazzagatti, Simone De Angelis, Sarah C. Johnson, Bjorn Bakker, Diana C. J. Spierings, René Wardenaar, Eleni Maniati, Jun Wang, Michael A. Boemo, Floris Foijer & Sarah E. McClelland
Additional file 2. Contains CNAs for RPE1 after treatment with DMSO, Aphidicolin or siRNA.

Additional file 8 of Novel trends of genome evolution in highly complex tropical sponge microbiomes

Joseph B. Kelly, David E. Carlson, Jun Siong Low & Robert W. Thacker
Additional file 8: Table S3. Table of genes and domains that are significantly enriched or depleted in Ircinia, and which are plotted in Fig. 2.

Additional file 10 of Novel trends of genome evolution in highly complex tropical sponge microbiomes

Joseph B. Kelly, David E. Carlson, Jun Siong Low & Robert W. Thacker
Additional file 10: Data File S1. Fasta-formatted CSGs found in bacterial symbionts of Ircinia.

Supplemental Material, original_data - Effectiveness of Continuous Positive Airway Pressure Versus Mandibular Advancement Device in Severe Obstructive Sleep Apnea Patients With Mandibular Retrognathia: A Prospective Clinical Trial

Haichun Lai, Wei Huang, Wei Chen & Desheng Wang
Supplemental Material, original_data for Effectiveness of Continuous Positive Airway Pressure Versus Mandibular Advancement Device in Severe Obstructive Sleep Apnea Patients With Mandibular Retrognathia: A Prospective Clinical Trial by Haichun Lai, Wei Huang, Wei Chen and Desheng Wang in Ear, Nose & Throat Journal

Additional file 2 of Development and validation of an extended Cox prognostic model for patients with ER/PR+ and HER2− breast cancer: a retrospective cohort study

Yiqun Xie, Xizhou Li, Ying Wu, Wenting Cui & Yang Liu
Additional file 2: Appendix 2. Hazard ratios and their 95% confidence limits of Ki67, PR, ER, and age. Figure 1. Hazard ratios and their 95% confidence limits for a series of binary variables of Ki67. Figure 2. Hazard ratios and their 95% confidence limits for a series of binary variables of ER. Figure 3. Hazard ratios and their 95% confidence limits for a series of binary variables of PR. Figure 4. Hazard ratios and their...

Additional file 2 of Cross-watershed distribution pattern challenging the elimination of Oncomelania hupensis, the intermediate host of Schistosoma japonicum, in Sichuan province, China

Shen Chen, Ding Lu, Lei Duan, Ben Ma, Chao Lv, Yin-long Li, Shen-ning Lu, Lan-hua Li, Liang Xu, Zi-song Wu, Shang Xia, Jing Xu, Yang Liu & Shan Lv
Additional file 2: Dataset S1. The 130 unique cox1 haplotypes of Oncomelania hupensis from this study including two outgroups

Preparation of bisDOPO-NH2-POSS flame retardant and its application to plywood using modified urea-formaldehyde resin

Mingyu Wen, Junxian Xu, Jiazhi Zhu, Yang Liu, Chao Deng, Junyou Shi & Heejun Park
A new type of polyhedral oligomeric silsesquioxanes bisDOPO-NH2-POSS flame retardant consisting of one polyhedral oligomeric silsesquioxane (POSS), two units of 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide (DOPO) and reactive –NH2 groups, was synthesized and characterized by FTIR, 1H NMR, and 31P NMR. It was applied to modified conventional environmentally friendly E0 grade urea formaldehyde (UF) resin to prepare flame-retardant plywood. Two other POSS structure flame retardants were used for comparison. The results showed that the addition of bisDOPO-NH2-POSS flame retardant...

IMPROVING EXPLOSIVE BODY CAPACITY IN FEMALE SHORT TRACK SPEED SKATERS

Jianjun Li, Xinchao Ge & Yang Liu
ABSTRACT Introduction The peculiar characteristics of short track speed skating should be integrated into the psychology of competitions; it is considered that elite athletes engaged in this particular sport should have a healthy psychic condition. Objective Investigate the explosive power of female speed skaters in short track speed skating. Methods 10 key athletes from the national short track speed skating team were selected, and explosive power was tested by T-test, hexagonal test, and pro sensitivity...

IMPACTS OF PHYSICAL COORDINATION TRAINING ON SPEED IN SHORT TRACK SPEED SKATING

Xinchao Ge, Jianjun Li & Yang Liu
ABSTRACT Introduction Although the development time of short-track speed skating in China is relatively short, with the joint efforts of many athletes and coaches, the special technical level can be comparable with that of European and American countries. Objective Verify the impacts of physical coordination training on speed in short track speed skating. Methods Athletes from the provincial skating team were randomly selected and distributed into control and experimental groups to apply the training method...

IMPACTS OF PHYSICAL COORDINATION TRAINING ON SPEED IN SHORT TRACK SPEED SKATING

Xinchao Ge, Jianjun Li & Yang Liu
ABSTRACT Introduction Although the development time of short-track speed skating in China is relatively short, with the joint efforts of many athletes and coaches, the special technical level can be comparable with that of European and American countries. Objective Verify the impacts of physical coordination training on speed in short track speed skating. Methods Athletes from the provincial skating team were randomly selected and distributed into control and experimental groups to apply the training method...

Additional file 2 of Sequential gene expression analysis of cervical malignant transformation identifies RFC4 as a novel diagnostic and prognostic biomarker

Jianwei Zhang, Silu Meng, Xiaoyan Wang, Jun Wang, Xinran Fan, Haiying Sun, Ruoqi Ning, Bing Xiao, Xiangqin Li, Yao Jia, Dongli Kong, Ruqi Chen, Changyu Wang, Ding Ma & Shuang Li
Additional file 2: Table S7. Enrichment of chromosomal region. Table S8. Simplified results of GO enrichment. Table S9. KEGG enrichment results.

RETRACTED ARTICLE: KIAA1429 promotes osteosarcoma progression by promoting stem cell properties and is regulated by miR-143-3p

Qicai Han, Jie Yang, Hao Yang, Chao Li, Juan Li & Yuan Cao
We, the Editors and Publisher of the journal Cell Cycle, have retracted the following article: Qicai Han, Jie Yang, Hao Yang, Chao Li, Juan Li & Yuan Cao (2020) KIAA1429 promotes osteosarcoma progression by promoting stem cell properties and is regulated by miR-143-3p, Cell Cycle, 19:10, 1172-1185, DOI: 10.1080/15384101.2020.1749465 Since publication, concerns have been raised about similarity of the data in another published article: Yang J, Han Q, Li C, Yang H, Chen X, Wang...

Additional file 26 of Proteogenomic insights into the biology and treatment of pancreatic ductal adenocarcinoma

Yexin Tong, Mingjun Sun, Lingli Chen, Yunzhi Wang, Yan Li, Lingling Li, Xuan Zhang, Yumeng Cai, Jingbo Qie, Yanrui Pang, Ziyan Xu, Jiangyan Zhao, Xiaolei Zhang, Yang Liu, Sha Tian, Zhaoyu Qin, Jinwen Feng, Fan Zhang, Jiajun Zhu, Yifan Xu, Wenhui Lou, Yuan Ji, Jianyuan Zhao, Fuchu He, Yingyong Hou … & Chen Ding
Additional file 26: Table S4. The Effects of Diabetes on the Proteogenomic Characteristics of PDAC. Table S4A Mutations and arm events information in PDAC patients with or without diabetes history. Table S4B Matrix of differential pathway enrichment in patients with or without diabetes history at mRNA level. Table S4C Matrix of differential pathway enrichment in patients with or without diabetes history at protein level.

Registration Year

  • 2022
    85
  • 2021
    26
  • 2020
    20
  • 2019
    8
  • 2018
    14
  • 2017
    18
  • 2016
    16
  • 2015
    13
  • 2014
    4
  • 2013
    8

Resource Types

  • Dataset
    220

Affiliations

  • Stony Brook University
    220
  • Chinese Academy of Medical Sciences & Peking Union Medical College
    65
  • Zhejiang University
    60
  • Shanghai Jiao Tong University
    60
  • Capital Medical University
    56
  • University of Chinese Academy of Sciences
    54
  • Sun Yat-sen University
    53
  • Fudan University
    53
  • China Agricultural University
    49
  • Chinese Academy of Sciences
    48