44,111 Works

Gabapentin for Neuropathic Pain: An application to the 21st meeting of the WHO Expert Committee on Selection and Use of Essential Medicines for the inclusion of gabapentin on the WHO Model List of Essential Medicines

Peter Kamerman, Nanna Finnerup, Liliana De Lima, Simon Haroutonian, Srinivasa Raja, Blair Smith, Andrew Rice & Rolf-Detlef Treede
ABOUTThis repository contains all the files required to generate the application (and supporting documents) the International Association for the Study of Pain (IASP) and the International Association of Hospice and Palliative Care (IAHPC) made to the 21st meeting of the WHO Expert Committee on Selection and Use of Essential Medicines (2017) for the inclusion of gabapentin on the WHO Model List of Essential Medicines for the treatment of neuropathic pain.For a brief summary of why...

Data from: Among-species overlap in rodent body size distributions predicts species richness along a temperature gradient

Quentin Read, John Grady, Phoebe Zarnetske, Sydne Record, Benjamin Baiser, Jonathan Belmaker, Mao-Ning Tuanmu, Angela Strecker, Lydia Beaudrot & Katherine Thibault
The associated data files and R script are all that is required to reproduce the analyses in the manuscript "A thermal gradient of trait similarity across North America," published in Ecography: https://onlinelibrary.wiley.com/doi/10.1111/ecog.03641
The following .csv files contain data required to reproduce the analysis, with raw unprocessed small mammal data from NEON, small mammal data that has been put through our QC code, mammal trait data compiled from different sources, and site-level environmental covariates: raw_NEON_mammal_data.csv, final_NEON_mammal_data.csv, mammal_traits.csv,...

Data from: Among-species overlap in rodent body size distributions predicts species richness along a temperature gradient

Quentin Read, John Grady, Phoebe Zarnetske, Sydne Record, Benjamin Baiser, Jonathan Belmaker, Mao-Ning Tuanmu, Angela Strecker, Lydia Beaudrot & Katherine Thibault
The associated data files and R script are all that is required to reproduce the analyses in the manuscript "A thermal gradient of trait similarity across North America," published in Ecography: https://onlinelibrary.wiley.com/doi/10.1111/ecog.03641
The following .csv files contain data required to reproduce the analysis, with raw unprocessed small mammal data from NEON, small mammal data that has been put through our QC code, mammal trait data compiled from different sources, and site-level environmental covariates: raw_NEON_mammal_data.csv, final_NEON_mammal_data.csv, mammal_traits.csv,...

Figure file and plotting code

Yan Li
Figure files for the paper "Li et al 2017, Estimating global ecosystem iso/anisohydry using active and passive microwave satellite data, JGR" and plotting codes in Python.

Figure file and plotting code

Yan Li
Figure files for the paper "Li et al 2017, Estimating global ecosystem iso/anisohydry using active and passive microwave satellite data, JGR" and plotting codes in Python.

Additional file 3: of DeepCpG: accurate prediction of single-cell DNA methylation states using deep learning

Christof Angermueller, Heather Lee, Wolf Reik & Oliver Stegle
Sequence motifs. HTML files with sequence logos and summary statistics for all cell types. (ZIP 19482Â kb)

Randomization Inference and Sensitivity Analysis for Composite Null Hypotheses With Binary Outcomes in Matched Observational Studies

Colin B. Fogarty, Pixu Shi, Mark E. Mikkelsen & Dylan S. Small
We present methods for conducting hypothesis testing and sensitivity analyses for composite null hypotheses in matched observational studies when outcomes are binary. Causal estimands discussed include the causal risk difference, causal risk ratio, and the effect ratio. We show that inference under the assumption of no unmeasured confounding can be performed by solving an integer linear program, while inference allowing for unmeasured confounding of a given strength requires solving an integer quadratic program. Through simulation...

Plant species and abundance records for burned and unburned areas

Erica Newman, David Hembry & Carlea Winkler
These data were collected from three sites with paired burned and unburned comparison areas (6 survey units). Plant species and their abundances were recorded on 5 transects in each survey unit, at 4 meter intervals, for a total of 390 data points. More information available with published article: https://peerj.com/articles/5114/ p.p1 {margin: 0.0px 0.0px 0.0px 0.0px; font: 12.0px 'Helvetica Neue'; color: #454545}

Plant species and abundance records for burned and unburned areas

Erica Newman, David Hembry & Carlea Winkler
These data were collected from three sites with paired burned and unburned comparison areas (6 survey units). Plant species and their abundances were recorded on 5 transects in each survey unit, at 4 meter intervals, for a total of 390 data points. More information available here: https://peerj.com/articles/5114/

Homogeneous earthquake catalogue for Northeast region of India using robust statistical approaches

Auchitya Kumar Pandey, Prasanta Chingtham & P. N. S. Roy
Regular seismic hazard assessment requires essentially an updated and refined homogenous earthquake catalogue for the study region. Here, we have compiled the earthquake data for Northeast region of India in a chronological order from International Seismological Centre and Global Centroid Moment Tensor databases during the period 1 January 1900 to 31 April 2016. For this purpose, the regression techniques such as least square (SR), inverse least square (ISR), orthogonal (OR) and generalized orthogonal (GOR) which...

Homogeneous earthquake catalogue for Northeast region of India using robust statistical approaches

Auchitya Kumar Pandey, Prasanta Chingtham & P. N. S. Roy
Regular seismic hazard assessment requires essentially an updated and refined homogenous earthquake catalogue for the study region. Here, we have compiled the earthquake data for Northeast region of India in a chronological order from International Seismological Centre and Global Centroid Moment Tensor databases during the period 1 January 1900 to 31 April 2016. For this purpose, the regression techniques such as least square (SR), inverse least square (ISR), orthogonal (OR) and generalized orthogonal (GOR) which...

Landslide manual and automated inventories, and susceptibility mapping using LIDAR in the forested mountains of Guerrero, Mexico

Krzysztof Gaidzik, María Teresa Ramírez-Herrera, Michael Bunn, Ben A. Leshchinsky, Michael Olsen & Netra R. Regmi
Landslides are a pervasive natural disaster, resulting in severe social, environmental and economic impacts worldwide. The tropical, mountainous landscape in South-West Mexico is predisposed to landslides because of frequent hurricanes and earthquakes. The main goal of this study is to compare landslide susceptibility maps in Guerrero derived using high-resolution LIDAR (light detection and ranging) data from both a manual landslide event inventory and an automated landslide inventorying algorithm. The paper also highlights the importance of...

Landslide manual and automated inventories, and susceptibility mapping using LIDAR in the forested mountains of Guerrero, Mexico

Krzysztof Gaidzik, María Teresa Ramírez-Herrera, Michael Bunn, Ben A. Leshchinsky, Michael Olsen & Netra R. Regmi
Landslides are a pervasive natural disaster, resulting in severe social, environmental and economic impacts worldwide. The tropical, mountainous landscape in South-West Mexico is predisposed to landslides because of frequent hurricanes and earthquakes. The main goal of this study is to compare landslide susceptibility maps in Guerrero derived using high-resolution LIDAR (light detection and ranging) data from both a manual landslide event inventory and an automated landslide inventorying algorithm. The paper also highlights the importance of...

Safety and effectiveness of high-dose methotrexate (over 8 mg/week) in 2838 Japanese patients with rheumatoid arthritis: A postmarketing surveillance report

Yasuo Suzuki, Naonobu Sugiyama, Yuri Fukuma, Noriko Sugiyama & Takeshi Kokubo
Objectives: To confirm the safety and effectiveness of high-dose (>8 mg/week) methotrexate (MTX) for the treatment of rheumatoid arthritis in Japan. Methods: A postmarketing surveillance program enrolled Japanese patients with rheumatoid arthritis starting on high-dose MTX followed up for either 24- or 52-weeks. Analyses for safety, risk factors affecting safety, and effectiveness were conducted. Results: The safety/effectiveness analysis sets included 2838/2779 and 335/326 patients in the 24-weeks and 52-weeks follow-up groups, respectively. Incidence rates of...

RETRACTED ARTICLE: Safety and effectiveness of high-dose methotrexate (over 8 mg/week) in 2838 Japanese patients with rheumatoid arthritis: A postmarketing surveillance report

Yasuo Suzuki, Naonobu Sugiyama, Yuri Fukuma, Noriko Sugiyama & Takeshi Kokubo
RETRACTED ARTICLE: Safety and effectiveness of high-dose methotrexate (over 8 mg/week) in 2838 Japanese patients with rheumatoid arthritis: A postmarketing surveillance report

RETRACTED ARTICLE: Safety and effectiveness of high-dose methotrexate (over 8 mg/week) in 2838 Japanese patients with rheumatoid arthritis: A postmarketing surveillance report

Yasuo Suzuki, Naonobu Sugiyama, Yuri Fukuma, Noriko Sugiyama & Takeshi Kokubo
RETRACTED ARTICLE: Safety and effectiveness of high-dose methotrexate (over 8 mg/week) in 2838 Japanese patients with rheumatoid arthritis: A postmarketing surveillance report

Gomez-Casanovas et al_EAP16-0667

Nuria Gomez-Casanovas, Nicholas DeLucia, Carl J Bernacchi, Elizabeth Boughton, Jed Sparks, Samuel Chamberlain & Evan H DeLucia
Description: Environmental (air temperature and precipitation) and soil variables (soil temperature and moisture) along with CO2 and CH4 fluxes for both grazed and ungrazed pastures. Environmental variables: Air temperature and precipitation values provided are daily averages. Soil variables: Soil temperature and moisture values provided are daily averages measured at 10 and 15-cm depth, respectively. CO2 and CH4 fluxes provided are half-hour gap filled values. Fluxes of CO2 were gap filled using the Eddy covariance gap-filling...

Gomez-Casanovas et al_EAP16-0667

Nuria Gomez-Casanovas, Nicholas DeLucia, Carl J Bernacchi, Elizabeth Boughton, Jed Sparks, Samuel Chamberlain & Evan H DeLucia
Description: Environmental (air temperature and precipitation) and soil variables (soil temperature and moisture) along with CO2 and CH4 fluxes for both grazed and ungrazed pastures. Environmental variables: Air temperature and precipitation values provided are daily averages. Soil variables: Soil temperature and moisture values provided are daily averages measured at 10 and 15-cm depth, respectively. CO2 and CH4 fluxes provided are half-hour gap filled values. Fluxes of CO2 were gap filled using the Eddy covariance gap-filling...

Raw data set for the manuscript PeerJ 11801 on Lid opening and conformational stability of T1 lipase is mediated by increasing chain length polar solvents.

Maiangwa Jonathan
This is a repository data set for peerJ publications

Raw data set for the manuscript PeerJ 11801

Maiangwa Jonathan
This is a repository data set for peerJ publications

Raw data set for the manuscript PeerJ 11801 on Lid opening and conformational stability of T1 lipase is mediated by increasing chain length polar solvents.

Maiangwa Jonathan
This is a repository data set for peerJ publications

Systematic review of the literature on triclosan and health outcomes in humans

Michael Goodman, Daniel Q. Naiman & Judy S. LaKind
The ability of epidemiologic evidence to inform regulatory decisions is largely dependent on the coherence and quality of the published literature. This systematic review examines the quality and consistency of studies assessing health outcomes associated with exposure to triclosan (TCS), an antimicrobial chemical with a short physiologic half-life. We used elements of the Biomonitoring, Environmental Epidemiology, and Short-Lived Chemicals instrument to evaluate aspects of study quality. Each methodological domain – overall design, exposure assessment, and...

Systematic review of the literature on triclosan and health outcomes in humans

Michael Goodman, Daniel Q. Naiman & Judy S. LaKind
The ability of epidemiologic evidence to inform regulatory decisions is largely dependent on the coherence and quality of the published literature. This systematic review examines the quality and consistency of studies assessing health outcomes associated with exposure to triclosan (TCS), an antimicrobial chemical with a short physiologic half-life. We used elements of the Biomonitoring, Environmental Epidemiology, and Short-Lived Chemicals instrument to evaluate aspects of study quality. Each methodological domain – overall design, exposure assessment, and...

Systematic review of the literature on triclosan and health outcomes in humans

Michael Goodman, Daniel Q. Naiman & Judy S. LaKind
The ability of epidemiologic evidence to inform regulatory decisions is largely dependent on the coherence and quality of the published literature. This systematic review examines the quality and consistency of studies assessing health outcomes associated with exposure to triclosan (TCS), an antimicrobial chemical with a short physiologic half-life. We used elements of the Biomonitoring, Environmental Epidemiology, and Short-Lived Chemicals instrument to evaluate aspects of study quality. Each methodological domain – overall design, exposure assessment, and...

Basis set limit coupled-cluster studies of hydrogen-bonded systems

A. Daniel Boese
As hydrogen-bonded systems are of utmost importance in especially biological and chemical systems, a new set of highly accurate reference dissociation energies, denoted HB49, is devised. For the molecules in this set, the basis set convergence of post-Hartree–Fock methods, including F12 methods, is investigated. Using combined Møller–Plesset perturbation theory (MP2) and CCSD(T) approaches for energies and MP2 and QCISD(T) for gradients, we achieve CCSD(T) accuracy, which has been determined before to yield an accuracy of...

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