521 Works

THE EFFECTS OF A STRENGTHS BASED FACULTY COACHING INTERVENTION ON FIRST-YEAR UNDERGRADUATE STUDENT ACADEMIC CONFIDENCE

Conrad Davies
Deficiency remediation models of education imply that students may enter the university with deficiencies, problems, or needs that imply the student needs to be “fixed” before they can proceed in their academic studies. In contrast, strengths-based education models infer that students come to the university with inherent talents, natural propensities, and behaviors that can be leveraged to overcome their challenges. These differing perspectives can influence the effectiveness of university policies designed to improve student retention....

Psychological Distress and Relationship Satisfaction Among Survivors of Sexual Violence

Alyssa Campbell
The World Health Organization (WHO; 2002) has indicated that sexual violence is a serious public health concern, and both the WHO and the United Nations (UN) have declared that violence against women, in particular, is a profound violation of human rights (UN General Assembly, 1993; WHO, 2017). Although the systemic and negative impact of trauma on family and intimate relationships have been well documented, the empirical literature regarding the effects of adult sexual trauma on...

INCORPORATION OF SUMMER ANNUAL MIXTURES INTO GRAZING SYSTEMS IN KENTUCKY

Kelly Mercier
Utilizing summer annual grass-legume forage mixtures has the potential to improve forage yield and nutritive characteristics, and/or animal performance during times when cool-season pasture growth is limited by high temperatures. Legumes can utilize atmospheric nitrogen, which can increase crude protein and forage digestibility in mixtures. As nitrogen application generally improves both the yield and nutritive characteristics of summer annual forages, but can have a negative effect on legume competitiveness, nitrogen fertilizer recommendations for legume-containing summer...

To “Reawaken The Conscience of Mankind”

Cody Foster
This dissertation looks at the International War Crimes Tribunal (IWCT) as a vessel for human rights’ ideas during the Vietnam War. I argue that the IWCT supported a transnational advocacy network that used the language of human rights to oppose the Vietnam War and rally support from those around the world who stood against American imperialism. On the one hand, the tribunal precedes the institutionalization of human rights in the 1970s. On the other, it...

ABC TRANSPORTERS IN GLIOBLASTOMA

Julia Schulz
Glioblastoma is one of the deadliest cancers, with a median survival of only one year. Even after aggressive treatment consisting of surgical resection, radiation, and chemotherapy, most glioblastoma patients suffer from tumor recurrence within 6-9 months. One reason for treatment failure of anticancer drugs is the blood-brain barrier that protects the brain by impeding xenobiotic uptake from the blood. To this end, efflux transporters at the human blood-brain barrier, such as P-glycoprotein (ABCB1) and Breast...

EXPLORING THE X-RAY UNIVERSE IN THE MICROCALORIMETER ERA

Priyanka Chakraborty
Next-generation microcalorimeter missions like XRISM and Athena will revolutionize X-ray spectroscopy by offering a plethora of high-resolution X-ray spectra. Interpreting these observations requires a complete understanding of how matter interacts with light through such microphysical processes as absorption and excitation. I developed a framework describing the atomic processes for both collisionally-ionized and photoionized plasmas over a wide range of column densities. Through various line-intensity and line-ratio spectral diagnostics, I established four asymptotic limits; Cases A,...

An Electrochemical-Mechanical Investigation of Next Generation Lithium Metal Electrode and Solid Electrolyte

Andrew Meyer
Lithium-ion batteries (LIBs) are a staple in today’s society. From our cellphones, laptops, power tools, the ever-growing electric vehicle, and many more application, LIBs are more important to us than most realize. They provide the best combination of both high-energy and high-power density compared to other battery types such as Ni-Cd, Ni-MH, or the lead acid batteries used in our cars. Plus, LIBs are much safer. However, as new technologies grow and are developed, the...

FIRST-GENERATION DOCTORAL STUDENTS’ EXPERIENCES NAVIGATING GRADUATE SCHOOL

Leah Vance-Berg
First-generation students who pursue graduate programs face a unique set of challenges and rely on their strengths to help them navigate their graduate programs. This study will look at how first-generation students have navigated their graduate course work. Semi-structured interviews were conducted with 19 doctoral students at Magnolia University where participants discussed the challenges they have faced during graduate school and how they have navigated these challenges. This exploratory study uses social and cultural capital...

SCIENCE-BASED REGULATION OF PHARMACOLOGICAL SUBSTANCES IN COMPETITION HORSES

Jacob Machin
Current testing methodologies within equine forensic toxicology focus on arbitrary thresholds and zero-tolerance policy. Modern analytical chemistry’s limits of detection are low enough that oftentimes femtogram-per-milliliter amounts of a substance can readily be identified in both blood and urine of a horse. For most pharmacologically relevant compounds, these concentrations have no relevance to pharmacological effect. It is therefore crucial that testing methodologies to determine appropriate thresholds and cut-offs be developed that are driven by biological...

Development and Cross-Validation of Personality Assessment Inventory Decision Rules for the Identification of Psychogenic Nonepileptic Seizures

Chelsea Bosch
The published literature on the Personality Assessment Inventory (PAI) for psychogenic nonepileptic seizure (PNES) diagnosis includes a variety of interpretation methods to distinguish PNES from epileptic seizures (ES) and offers mixed findings. The purpose of this study was to use a cross-validation approach to create and derive new decision rules for the PAI to best differentiate PNES from ES. Data from 773 patients (PNES n = 328, ES n = 445) who underwent long-term video...

Weakly Supervised Learning for Multi-Image Synthesis

Muhammad Usman Rafique
Machine learning-based approaches have been achieving state-of-the-art results on many computer vision tasks. While deep learning and convolutional networks have been incredibly popular, these approaches come at the expense of huge amounts of labeled data required for training. Manually annotating large amounts of data, often millions of images in a single dataset, is costly and time consuming. To deal with the problem of data annotation, the research community has been exploring approaches that require less...

AN ASSESSMENT OF THE CARRIER STATE AND A NOVEL MARKER OF LEPTOSPIRA AND ABORTION IN CENTRAL KENTUCKY HORSES

Gloria Gellin
Leptospirosis is a reemerging zoonotic infection of worldwide importance and affects all mammals. The bacterium is transmitted to animals and humans by urine, fetal membranes and body fluids. Leptospira shedding in the urine contaminates both soil and water, exposing both humans and animals to the bacterium. Leptospirosis in horses can cause abortion and is one of the etiologies of equine recurrent uveitis which can lead to blindness. Equine leptospiral abortion in Central Kentucky is primarily...

Myelin, cPLA2, and Azithromycin

Timothy Kopper
Spinal cord injury (SCI) produces a chronic inflammatory state primarily mediated by macrophages consisting of resident microglia and infiltrating monocytes. These chronically activated SCI macrophages adopt a pro-inflammatory, pathological state that continues to cause additional damage after the initial injury and inhibits recovery. While the roles of macrophages in SCI pathophysiology are well documented, the factors contributing to this maladaptive response are poorly understood. Here, we identify the detrimental effects of myelin debris on macrophage...

Revisiting Absolute Pose Regression

Hunter Blanton
Images provide direct evidence for the position and orientation of the camera in space, known as camera pose. Traditionally, the problem of estimating the camera pose requires reference data for determining image correspondence and leveraging geometric relationships between features in the image. Recent advances in deep learning have led to a new class of methods that regress the pose directly from a single image. This thesis proposes methods for absolute camera pose regression. Absolute pose...

THE EFFECTS OF FORM OF SELENIUM ON THE BOVINE CORPUS LUTEUM, UTERINE ENDOMETRIUM, AND DEVELOPMENT OF THE CONCEPTUS

Benjamin Ryne Crites
Widespread regions of the southeast United States have soils deficient in selenium (Se), necessitating Se supplementation to cattle grazing in these areas. Adequate dietary Se is required for optimal immune function, growth, and fertility. In forages, Se is predominantly found in the organic form (OSe), which is known to increase bioavailability. However, the inorganic form (ISe) is typically found in commercial mineral mixes. We previously reported that supplementation with an isomolar 1:1 mix (MIX) of...

Mobile Technology Use During the COVID-19 Pandemic

Yi Lin
The COVID-19 pandemic led to quarantines and mandatory spatial distancing; people of all ages were encouraged to use technologies instead of actual human contact for COVID-19 prevention and daily activities. The special circumstances of living plus innovation and promotion of mobile applications (apps) during the pandemic influenced mobile technology use behavior. In this study we explored age differences in mobile technology use, the factors that influenced use behavior during the COVID-19 pandemic, and proposed a...

UNDERSTANDING ABSORPTION, SUPERSATURATION, AND DRUG ACTIVITY IN SOLUTION

Freddy Arce
With the looming dominance of poorly water-soluble chemical entities within the pharmaceutical pipeline, the pharmaceutical industry has leaned on the use of supersaturating drug delivery systems (SDDSs) to achieve efficacious concentrations within the gastrointestinal fluids. SDDSs aim to achieve concentrations in solutions greater than the solubility of the lowest energy crystalline form. However, the generation of supersaturated solutions of active pharmaceutical ingredients (APIs) creates a strong crystallization potential, which is undesirable. In product development, supersaturating...

SUCCINYLATED POLYETHYLENIMINE GENE DELIVERY AGENTS FOR ENHANCED TRANSFECTION EFFICACY

MdNasir Uddin
Gene therapy aims to treat patients by altering or controlling gene expression. Today, most clinical approaches are viral-based due to their inherent gene delivery activity. However, there is still a significant interest in nonviral alternatives for gene delivery, particularly synthetic lipids and polymers, that do not suffer the immunogenicity, high cost, or mutagenesis concerns of viral vectors. Polymeric vectors are of particular interest due to the ability to further tune the polymer properties through the...

PARENTAL BARRIERS TOWARD SEEKING MENTAL HEALTHCARE FOR SAUDI CHILDREN AT RISK OF ADHD

Amani Kappi
Attention deficit hyperactivity disorder (ADHD) is a mental health disorder commonly diagnosed in childhood. Underdiagnosis and undertreatment of ADHD can lead to the development of other mental illnesses and disruptions in social functioning in adulthood. Therefore, parents can play a crucial role in proactively seeking mental healthcare for children who are at risk for or who have a clear diagnosis of ADHD. Studies in the United Kingdom and the United States highlight many barriers that...

Early Maturing Out of Problematic Alcohol Use

Sarah Peterson
Most research suggests that alcohol use peaks in the college years then declines into the mid-thirties (Jochman & Fromme, 2010). However, there is evidence that some individuals mature out earlier: downward trends for some individuals begin in college, with as many as one third of students decreasing their drinking (Baer et al., 2001). It is crucial to identify factors that differentiate those who decrease their drinking early from those who persist in high levels of...

TURNING THE TIDES

Sarah Geegan
Extensive research, predating and during the COVID-19 pandemic, demonstrates the rising prevalence of anxiety and depression among Gen Z college students in the United States—findings which are accompanied by rising rates of suicide, the second leading cause of death among people aged 15-24. Although college campuses often offer mental health resources, the number of college students utilizing them is significantly less than the number of students reporting mental health challenges. A dearth of empirical evidence,...

Regulation of Skeletal Muscle Plasticity by the Gut Microbiome

Taylor Valentino
Recent evidence suggests that the gut microbiome could play a role in skeletal muscle plasticity, providing novel treatments for muscle wasting diseases and/or performance enhancements. I first sought to determine if the gut microbiome is necessary for skeletal muscle adaptation to exercise. Forty-two, four-month old, female C57Bl/6J underwent nine weeks of weighted wheel running or remained in cage with a locked wheel, without or without the administration of antibiotics (treated). In response to wheel running,...

LA REPRESENTACIÓN DE LA MASCULINIDAD EN EL PERSONAJE DEL POLICÍA

Daniel Fonfría-Perera
This research focuses on the type of hegemonic masculinity—a term that has traditionally belonged to a purely sociology domain—exhorted in the works of fiction published and released in Spain in the last two decades, searching for patterns that indicate that a normative type is encouraged. After tracing the different types of hegemonic masculinities that have characterized policemen since the late 30’s, the findings show how the modern notion of masculinity depicted in the works analyzed,...

The Hybrid Teacher:

Mary Joy Nelson
The world of professional vocal training is becoming more and more eclectic and demanding in the United States. Academic music programs, and subsequently, vocal and vocal pedagogy programs are still predominantly classical in 2022, due to the American university system’s historical roots. In the 21st century, the commercial music industry is at an all-time high. However, in contemporary academia, vocal and vocal pedagogy degree programs remain primarily classical. In recent years, voice professionals have been...

SOCIAL CONSTRUCTION OF HATE CRIMES IN THE US

Chenghui Zhang
Hate crime is a social construct that is conceptualized and defined through judgments about the meaning of bias and prejudice, as well as the causal link between motivation and criminal act. While the enforcement of federal statutes has extended the protected grounds of hate crime, significant underreporting issues impede the understanding of the actual scale, scope, and severity of hate crimes. The purpose of this dissertation is to investigate what and how incident factors and...

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