497 Works

Inverse Boundary Value Problems for Polyharmonic Operators With Non-Smooth Coefficients

Landon Gauthier
We consider inverse boundary problems for polyharmonic operators and in particular, the problem of recovering the coefficients of terms up to order one. The main interest of our result is that it further relaxes the regularity required to establish uniqueness. The proof relies on an averaging technique introduced by Haberman and Tataru for the study of an inverse boundary value problem for a second order operator.

The Fantastic Debate

Morgan Keith Stewart
This dissertation analyzes fantastic short fiction in terms of its relationship to the traditionalist and progressive forces that were vying for hegemonic control over Spanish national identity in the ever-changing period of the nineteenth century, demonstrating how these powers shaped Spain’s past and future national character to suit ideologically driven narratives and revealing how fantastic literature can disrupt these narratives to unlock new patterns of thought. In Chapter 1, entitled “Fantastic Short Fiction and National...

KAROL LIPIŃSKI AS A MUSICAL INTERPRETER IN THE PRE-JOACHIM ERA

Andrzej Kunecki
The work concerns a study of Karol Lipiński – the early nineteenth century Polish violinist – focusing on his activity as a musical interpreter. The work is supported by a comparison with another violinist acknowledged in this field – Joseph Joachim. The work is divided between four chapters: The first chapter begins with a discussion on the development of the concept of musical interpretation in the context of the broader social and aesthetical changes of...

Tropical Geometry of T-Varieties with Applications to Algebraic Statistics

Joseph Cummings
Varieties with group action have been of interest to algebraic geometers for centuries. In particular, toric varieties have proven useful both theoretically and in practical applications. A rich theory blending algebraic geometry and polyhedral geometry has been developed for T-varieties which are natural generalizations of toric varieties. The first results discussed in this dissertation study the relationship between torus actions and the well-poised property. In particular, I show that the well-poised property is preserved under...

Social and Biological Determinants of Pregnancy-Related Mortality and Morbidity in a Rural, Underserved Population

Anna Hansen
Cases of severe maternal morbidity (SMM) and pregnancy-related mortality (PRM) are increasing in the US. Research concerning SMM and PRM has neglected women in Central Appalachia; a largely rural, health-disparate population. The aims of this study are two-fold: (1) Examine patient-level and place-based predictors of SMM/PRM via hierarchical logistic regression modeling, and (2) Elucidate Appalachian healthcare patients’ and providers’ experiences with SMM/PRM, perceptions of contributing factors, and insights on points of intervention. This study uses...

When Should Sales Managers Get Involved in Their Salesteams' Transactions

Daniel E. Chavez
The existing literature on sales teams explores various aspects of team members and their effects on sales performance. The literature on sales management has described how managers can promote better results from salespeople. The question at the intersection of these two streams of literature – if managers should be part of sales teams -- has not been addressed and is what we explore. Using data from a Fortune 1,000 firm that operates automotive service stores...

Models and Optimal Controls for Smart Homes and their Integration into the Electric Power Grid

Huangjie Gong
Smart homes can operate as a distributed energy resource (DER), when equipped with controllable high-efficiency appliances, solar photovoltaic (PV) generators, electric vehicles (EV) and energy storage systems (ESS). The high penetration of such buildings changes the typical electric power load profile, which without appropriate controls, may become a “duck curve” when the surplus PV generation is high, or a “dragon curve” when the EV charging load is high. A smart home may contribute to an...

Quantifying Crop Phenology for Food Sustainability under Climate Change

yanjun yang
Climate change is projected to continue and accelerate significantly in the future if global greenhouse gas emissions are not curbed. Previous studies have shown that crop growth and production in agroecosystems are primarily determined by the weather conditions over the growing season. Crop phenology represents one of the most critical indicators in determining crop yield and adjusting the adaptation of crops to climate change. It provides essential information for monitoring and modeling crop growth dynamics...

QUANTITATIVE METHODS FOR TOTAL LIFECYCLE RISK LIKELIHOOD AND IMPACT ASSESSMENT IN SUSTAINABLE PRODUCT DESIGN DECISION MAKING

Christian Enyoghasi
Sustainable products promise significant economic, environmental, and societal benefits. Numerous methods are available for use during the new product development process to identify alternate product designs that optimize sustainability performance. Once any such design is selected and the product is launched, many uncertainties are likely to affect its performance over the total lifecycle. Such uncertainties give rise to risks that can influence the overall product sustainability performance. However, comprehensive quantitative methods to evaluate the likelihood...

Structural basis of bacterial flagellin for NAIP5 binding and NLRC4 inflammasome activation and the mechanism of flagellin induced release of cytokines in vivo

Jian Cui
The bacterial flagellum is a whip-like structure that protrudes from the cell membrane and is one of the most complex and dynamic biological molecular machines that propels bacteria to swim toward beneficial environments and the sites of infection. It is composed of a basal body, a hook, and a long filament. The flagellar filament contains thousands of copies of the protein flagellin (FliC) monomer arranged helically and ending with a filament cap composed of oligomer...

OTAVALAN WOMEN WEAVERS

Kaitlin Zapel
This research focuses on the gendered labor of craft production and distribution of Otavaleños, an indigenous group in the Imbabura Valley in the Andes Mountains of Ecuador. Otavalans are often described as a society of weavers with strong gender divisions. Households typically function as units of production, with tasks ideally broken down along gender lines. Women are generally depicted as secondary workers who do not weave the textiles that make Otavalans famous; however, they are...

Mild Cognitive Impairment in Presurgical Deep Brain Stimulation for Parkinson's Disease

Elizabeth Wallace
Although clinically characterized by motor impairments, Parkinson's disease (PD) often affects cognition early in the disease course. Cognitive changes common in PD include visuospatial abnormalities and prominent executive function (EF) deficits, with 30% of individuals eventually developing Parkinson’s disease dementia (PDD). Mild cognitive impairment (MCI) has been identified as a transitional state between normal cognition and PDD. A large cohort of individuals with PD at the Kentucky Neuroscience Institute have undergone pre-surgical evaluations for deep...

Analysis of Graded Sensorimotor Rhythms for Brain-Computer Interface Applications

Chase Haddix
The emerging field of neural engineering is tasked with applying engineering principles towards understanding neuroscience. A by-product of such a venture has been the development of a class of assistive devices known as brain-computer interfaces (BCIs) which link brain activity to actions performed by external devices. One application of this technology is in the rehabilitative sector for individuals with neuromuscular diseases and disorders. Despite tremendous efforts in the last few decades, a reliable signal that...

INVESTIGATING THE ROLE OF CHD7 AND SOX11 IN RETINAL CELL DEVELOPMENT AND THE OCULAR COMPLICATIONS OF CHARGE SYNDROME

Laura Krueger
Proper formation of the visual system requires the precise interaction of several embryonic cell lineages, including the neuroectoderm (forms the retina and retinal pigment epithelium), surface ectoderm (forms the lens), mesoderm and cranial neural crest cells (form the ocular blood vessels and anterior ocular structures). When this process is disrupted structural birth defects such as coloboma result, leading to pediatric visual deficits. Ocular developmental defects are often present in larger syndromic disorders. One example is...

Interleukin-1 Receptor 1 signaling in mild TBI

Colleen N. Bodnar
Across the world, over 69 million people sustain a traumatic brain injury (TBI) per year making TBI a major health concern worldwide. Of all the TBIs that occur each year, it is suggested that up to 90 percent are mild in nature. Even a mild TBI causes both physical damages to the cells of the brain and activation of a variety of biochemical cascades. Inflammation is an extremely common pathology seen in the brains of...

THREE ESSAYS ON FOOD SAFETY AND PRIVATE FOOD SAFETY CERTIFICATIONS

Lijiao Hu
In the first essay, we provide a comprehensive literature review of the market of private food safety standards. Since the inception of private food safety standards in the late 1990s, producers, processors, retailers, and governments have been increasingly relying on them to provide assurances to food safety. This article first develops a conceptual framework for the market of private food safety standards through the lens of agri-food supply chain logistics, outlining how the key players...

FROM FEAR TO ACTION

Michele ("Micki") Olson
The extended parallel process model (EPPM) is a popular health and risk communication theory that explicates the relationship between perceived threat, perceived efficacy, fear, and adaptive and maladaptive responses. This study examines the EPPM in an imminent threat context and focuses on how warning message content influences EPPM perceptions and how these perceptions, in turn, influence both protective action and information seeking intentions. The first objective of this study focuses on applying the EPPM to...

The Utilization of Physical Literacy to Understand Physical Activity in Individuals with a History of Anterior Cruciate Ligament Reconstruction

Rachel Kleis
Injury to the anterior cruciate ligament (ACL) is common in physically active populations. Anterior cruciate ligament reconstruction (ACLR) is commonly performed after injury in order to restore joint stability and knee function and return patients to desired levels of physical activity. However, not everyone will return to their pre-injury levels of sport after surgery and recent evidence reveals that individuals with a history of ACLR are less likely to meet the recommended physical activity guidelines....

DEVELOPMENT AND PSYCHOMETRIC TESTING OF AN INSTRUMENT TO IDENTIFY FACTORS THAT PREDICT INTENTIONS RELATED TO POST-MORTEM ORGAN DONATION AMONG SAUDI ARABIAN NURSES

Salman Alreshidi
Organ donation shortage is a major international concern. Global data on organ donation and transplantation activities from the World Health Organization indicate that in 2019 organs were available for less than 10% of transplantations needed. In Saudi Arabia alone, the organ donation shortage accounts for 28.8% of deaths annually. Nearly 31% of donated organs are from donors outside of the country because many eligible donors in Saudi Arabia do not donate. While post-mortem organ donation...

The microbiome of the equine roundworm, Parascaris spp.

Jennifer Cain
Parasitic nematodes, including the large roundworms colloquially known as ascarids, affect the health and well-being of livestock animals worldwide. The equine ascarid, Parascaris spp., was the first ascarid parasite to develop wide-spread anthelmintic drug resistance, with other species slowly following suit. There are no new classes of anthelmintics currently in development, and a solution to the ever-increasing prevalence of resistance is desperately needed. The microbiome has been shown to be an important factor in the...

The Development and Validation of the Preservice Music Teacher Self-Efficacy Survey

Christen Dillon
Undergraduate programs to prepare future music teachers at colleges and universities across the United States require skill development in instrumental, choral, and general music (NASM, 2015). These preparation programs require students to matriculate through methods courses (e.g., instrumental methods) to learn pedagogical and content skills necessary to be considered competent music teachers. Although content knowledge and teaching skills could be influencing factors on preservice teachers’ future classroom effectiveness, personal beliefs of individual preservice teachers might...

NOVEL MECHANISM OF ENDOGENOUS PANCREATIC CANCER CELL EXPRESSION OF IMMUNE CHECKPOINT PROGRAMMED CELL-DEATH 1 PROTEIN (PD-1) INDUCING EPITHELIAL-TO-MESENCHYMAL TRANSITION (EMT) THROUGH THE MET PATHWAY AND PROMOTING CANCER PROGRESSION IN AN IMMUNE-INDEPENDENT PROCESS

Megan Harper
Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest cancers with few treatment options, necessitating an urgent need for novel therapeutics. Immuno-oncologic (IO) therapies have revolutionized anti-cancer regimens in the past decade but typically involve reactivation of adaptive immune responses. In particular, immune checkpoint PD-1 is traditionally expressed only on immune cells while PD-L1 (PD-1 ligand) is overexpressed on cancer cells. When tumor-endogenous PD-L1 binds the PD-1 receptor on T-cells, the immune cells undergo anergy...

EXPERIENTIAL-BASED FEEDBACK DURING ALCOHOL INTOXICATION AND ITS EFFECT ON DRINKERS’ RISK AWARENESS

Alexandra Kelly
The prevalence of alcohol-impaired driving injuries and fatalities has not decreased for over a decade despite strategies to reduce and prevent driving under the influence of alcohol (DUI). In 2019, 10,142 people died in alcohol-impaired driving crashes in the United States, which totaled to 28% of all traffic fatalities for the year. DUI interventions have been found to have moderate effects on reducing DUI recidivism. Prevention research has identified a lack of risk awareness in...

THE ISOLATED AS THE REVOLUTIONARY

Ruwen Chang
In contemporary China, demographers estimate that 30 million men are single because there are simply not enough women in the Chinese population, and the 2020 Chinese census shows that there are 34.9 million more men than women. These men are called guanggun, which can be directly translated to “bare sticks/branches,” a slur that indicates a lack of marriage and sex. In this project, I demonstrate that guanggun’s singlehood marks them as the marginalized at the...

THE EFFECTIVENESS OF HANDWRITING INTERVENTION ON HANDWRITING AND SPELLING OUTCOMES DELIVERED VIA TELEHEALTH

Laura Bray
Across the United States, there has been a push to improve the literacy of our population, especially in the school systems. This has resulted in emphasizing reading skill development; however, literacy encompasses more than just reading. Literacy is the internal processes needed to create and understand contextualized visual, written, and verbal information. According to the Common Core State Standards, foundational literacy skills include reading, but also writing, listening, and speaking abilities. Handwriting is an area...

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