2 Works

Homeobox A5 activates p53 pathway to inhibit proliferation and promote apoptosis of adrenocortical carcinoma cells by inducing Aldo-Keto reductase family 1 member B10 expression

Danyan Chen, Zhaonan Shen, Xi Cheng, Qi Wang, Junlin Zhou, Fang Ren, Yue Sun, Hongman Wang & Rongxi Huang
Figure published via Taylor & Francis
Aldo-Keto Reductase Family 1 Member B10 (AKR1B10) and Homeobox A5 (HOXA5) are both down-regulated in adrenocortical carcinoma (ACC), and HOXA5 is predicted to bind to the promoter of AKR1B10. We aimed to investigate whether HOXA5 could bind to AKR1B10 to regulate ACC cells proliferation and apoptosis. The expression of AKR1B10 and HOXA5 in ACC patients and the relationship of their expression between ACC prognosis were evaluated by searching database. Then, NCI-H295R cells were overexpressed to...
No citations were reported. No usage information was reported.
https://doi.org/10.6084/m9.figshare.14655567 Cite

Homeobox A5 activates p53 pathway to inhibit proliferation and promote apoptosis of adrenocortical carcinoma cells by inducing Aldo-Keto reductase family 1 member B10 expression

Danyan Chen, Zhaonan Shen, Xi Cheng, Qi Wang, Junlin Zhou, Fang Ren, Yue Sun, Hongman Wang & Rongxi Huang
Figure published via Taylor & Francis
Aldo-Keto Reductase Family 1 Member B10 (AKR1B10) and Homeobox A5 (HOXA5) are both down-regulated in adrenocortical carcinoma (ACC), and HOXA5 is predicted to bind to the promoter of AKR1B10. We aimed to investigate whether HOXA5 could bind to AKR1B10 to regulate ACC cells proliferation and apoptosis. The expression of AKR1B10 and HOXA5 in ACC patients and the relationship of their expression between ACC prognosis were evaluated by searching database. Then, NCI-H295R cells were overexpressed to...
No citations were reported. No usage information was reported.
https://doi.org/10.6084/m9.figshare.14655567.v1 Cite

Registration Year

  • 2021
    2

Resource Types

  • Image
    2

Affiliations

  • State Administration of Traditional Chinese Medicine of the People's Republic of China
    2
  • West China Hospital of Sichuan University
    2
  • Zhejiang University
    2
  • Jiangxi Agricultural University
    2
  • Central South University
    2
  • Jilin University
    2
  • Air Force Medical University
    2
  • Huazhong University of Science and Technology
    2
  • Anhui University of Science and Technology
    2
  • Sichuan University
    2

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