166 Works

Role of lncRNA LINC01194 in hepatocellular carcinoma via the miR-655-3p/SMAD family member 5 axis

Yang Liu, Jie Liu, Junkai Cui, Ruolei Zhong & Guoyang Sun
Long non-coding RNAs (lncRNAs) are involved in developing hepatocellular carcinoma (HCC). The present study explored the role of lncRNA LINC01194, which is upregulated in HCC tissues and might be a vital regulator in HCC progression. Levels of LINC01194, microRNA (miR)-655-3p, and SMAD family member 5 (SMAD5) were assessed using reverse transcription quantitative real-time polymerase chain reaction (RT-qPCR). The bioactivity of Huh-7 cells was assessed using cell counting kit-8 and transwell assays and flow cytometry. Western...

Ultrasound targeted microbubble destruction-mediated SOCS3 attenuates biological characteristics and epithelial-mesenchymal transition (EMT) of breast cancer stem cells

Xiaojiang Tang, Na Hao, Yuhui Zhou & Yang Liu
SOCS3 is low-expressed in breast cancer and may be a potential target. Ultrasound targeted microbubble destruction (UTMD) improved the efficiency of gene transfection. We explored the effects of UTMD-mediated transfection of SOCS3 on the biological characteristics and epithelial-mesenchymal transition (EMT) of breast cancer stem cells (BCSCs). The expression of SOCS3 in breast cancer (BC) and its association with prognosis were evaluated by GEPIA and The Cancer Genome Atlas (TCGA) websites. BCSCs were sorted by flow...

Inhibition of translocator protein 18 kDa suppressed the progression of glioma via the ELAV-like RNA-binding protein 1/MAPK-activated protein kinase 3 axis

Jingya Wang, Peng Ren, Zhirui Zeng, Li Ma, Yunjun Li, Hongmei Zhang & Wenzhi Guo
Glioma is the most common primary malignant brain tumors in adults. Despite considerable advances in treatment, the clinical outcome remains dismal. Translocator protein 18 kDa (TSPO), an evolutionarily conserved transmembrane protein, has always been found to be elevated in glioma, which predicts a poor prognosis. However, studies on the regulatory network of TSPO in glioma are limited. The Cancer Genome Atlas (TCGA) and our research group cohorts demonstrated that TSPO expression was also highly expressed...

Additional file 3 of Identification of pyroptosis-related genes and long non-coding RNAs signatures in osteosarcoma

Jian Zhang, Jianjian Deng, Rui Ding, Jinghong Yuan, Jiahao Liu, Xiaokun Zhao, Tianlong Wu, Jingyu Jia & Xigao Cheng
Additional file 3: Fig. S1. A, B PCA based on the six pyroptosis-related genes signature. C, D The relationship between the risk score and metastasis. E-G The nomogram calibration curves for predicting 1-, 3-, and 5-year survival in the GSE21257 cohort. H Kaplan–Meier analysis based on the pan-cancer data set and univariate Cox regression analysis of CHMP4C. I The expressions of CHMP4C in tumor and adjacent normal tissues.

Additional file 4 of Identification of pyroptosis-related genes and long non-coding RNAs signatures in osteosarcoma

Jian Zhang, Jianjian Deng, Rui Ding, Jinghong Yuan, Jiahao Liu, Xiaokun Zhao, Tianlong Wu, Jingyu Jia & Xigao Cheng
Additional file 4: Fig. S2. The PPI network.

sj-tif-5-tej-10.1177_20417314221132093 – Supplemental material for A new cell-free therapeutic strategy for liver regeneration: Human placental mesenchymal stem cell-derived extracellular vesicles

Ting Li, Yu Fu, Zeyi Guo, Honglei Zhu, Hangyu Liao, Xiaoge Niu, Lin Zhou, Shunjun Fu, Yang Li, Shao Li, Lujia Wang, Yizhou Zheng, Lei Feng, Yi Gao & Guolin He
Supplemental material, sj-tif-5-tej-10.1177_20417314221132093 for A new cell-free therapeutic strategy for liver regeneration: Human placental mesenchymal stem cell-derived extracellular vesicles by Ting Li, Yu Fu, Zeyi Guo, Honglei Zhu, Hangyu Liao, Xiaoge Niu, Lin Zhou, Shunjun Fu, Yang Li, Shao Li, Lujia Wang, Yizhou Zheng, Lei Feng, Yi Gao and Guolin He in Journal of Tissue Engineering

sj-jpg-2-tej-10.1177_20417314221132093 – Supplemental material for A new cell-free therapeutic strategy for liver regeneration: Human placental mesenchymal stem cell-derived extracellular vesicles

Ting Li, Yu Fu, Zeyi Guo, Honglei Zhu, Hangyu Liao, Xiaoge Niu, Lin Zhou, Shunjun Fu, Yang Li, Shao Li, Lujia Wang, Yizhou Zheng, Lei Feng, Yi Gao & Guolin He
Supplemental material, sj-jpg-2-tej-10.1177_20417314221132093 for A new cell-free therapeutic strategy for liver regeneration: Human placental mesenchymal stem cell-derived extracellular vesicles by Ting Li, Yu Fu, Zeyi Guo, Honglei Zhu, Hangyu Liao, Xiaoge Niu, Lin Zhou, Shunjun Fu, Yang Li, Shao Li, Lujia Wang, Yizhou Zheng, Lei Feng, Yi Gao and Guolin He in Journal of Tissue Engineering

Additional file 10 of System analysis based on the pyroptosis-related genes identifies GSDMC as a novel therapy target for pancreatic adenocarcinoma

Cheng Yan, Yandie Niu, Feng Li, Wei Zhao & Liukai Ma
Additional file 10: Figure S10. A.443654 inhibits the cell proliferation of PAAD. (A) Cell viability of PANC-1 cell line treated with DMSO and 50 nM A.443654, respectively. *P < 0.05, **P < 0.01 by a two-tailed unpaired t-test. (B) Colony formation assay of PANC-1 cells treated with DMSO and 50 nM A.443654, respectively. **P < 0.01 by a two-tailed unpaired t-test. (C) Edu assay of PANC-1 cells treated with DMSO and 50 nM A.443654, respectively....

Additional file 1 of System analysis based on the pyroptosis-related genes identifies GSDMC as a novel therapy target for pancreatic adenocarcinoma

Cheng Yan, Yandie Niu, Feng Li, Wei Zhao & Liukai Ma
Additional file 1: Figure S1. Functional enrichment analyses of gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG). (A) Bubble graph for GO enrichment (the bigger bubble means the more genes enriched, and the increasing depth of red means the differences were more obvious; q-value: the adjusted p-value). (B) KEGG enrichment analysis of differentially expressed genes.

Additional file 3 of System analysis based on the pyroptosis-related genes identifies GSDMC as a novel therapy target for pancreatic adenocarcinoma

Cheng Yan, Yandie Niu, Feng Li, Wei Zhao & Liukai Ma
Additional file 3: Figure S3. Risk model independent prognostic analysis. (A) Univariate independent prognosis Cox regression analysis of risk score and indicated clinical characteristics. (B) Multivariate independent prognosis Cox regression analysis of risk score and indicated clinical characteristics.

Additional file 6 of System analysis based on the pyroptosis-related genes identifies GSDMC as a novel therapy target for pancreatic adenocarcinoma

Cheng Yan, Yandie Niu, Feng Li, Wei Zhao & Liukai Ma
Additional file 6: Figure S6. The correlation of immune infiltrating cells with risk scores was determined in the training set. (A) Boxplots represent the level of different types of immune infiltrating cells in high- and low- risk group. (B-F) the correlation between the risk score and immune infiltrating cells was further examined by Spearman correlation analysis. *p < 0.05, ***p < 0.001.

Additional file 9 of System analysis based on the pyroptosis-related genes identifies GSDMC as a novel therapy target for pancreatic adenocarcinoma

Cheng Yan, Yandie Niu, Feng Li, Wei Zhao & Liukai Ma
Additional file 9: Figure S9. Overexpression GSDMC promotes cell proliferation and invasion in PAAD. (A)PANC-1 (left panel) and CFPAC-1 (right panel) cells were subjected to immunoblotting as indicated. (B, C) Cell growth of PANC-1 cells (B) and CFPAC-1 cells (C) were measured by CCK-8 assay. *P < 0.05, **P < 0.01 by two-way ANOVA. (D, F) Clone formation of PANC-1 cells (D) and CFPAC-1 cells (F) were measured as indicated ***P < 0.001 by a...

Additional file 1 of 3D-printed hemipelvic prosthesis combined with a dual mobility bearing in patients with primary malignant neoplasm involving the acetabulum: clinical outcomes and finite element analysis

Miao Wang, Tianze Liu, Changli Xu, Chang Liu, Bo Li, Qiujian Lian, Tongjiang Chen, Suchi Qiao & Zhiwei Wang
Additional file 1: Figure S1. The figure file shows the proceeding of soft tissue reconstruction in more detail.

Additional file 9 of Dynamic monitoring of cerebrospinal fluid circulating tumor DNA to identify unique genetic profiles of brain metastatic tumors and better predict intracranial tumor responses in non-small cell lung cancer patients with brain metastases: a prospective cohort study (GASTO 1028)

Meichen Li, Jing Chen, Baishen Zhang, Juan Yu, Na Wang, Delan Li, Yang Shao, Dongqin Zhu, Chuqiao Liang, Yutong Ma, Qiuxiang Ou, Xue Hou & Likun Chen
Additional file 9: Fig. S9 Mutational profilesof CSF and plasma samples at baseline and after 8 weeks of treatment.

Additional file 1 of Association of haemoglobin glycation index with outcomes in patients with acute coronary syndrome: results from an observational cohort study in China

Jiayu Li, Yanguo Xin, Jingye Li, Li Zhou, Hui Qiu, Aidong Shen, Hui Chen & Hongwei Li
Additional file 1: Figure S1. Adjusted RCS of HGI and the incidence of all-cause death (A), CV death (B), non-fatal MI (C), cardiac rehospitalization (D), revascularization (E), non-fatal stroke (F). Adjusted model included age, BMI, heart rate, hypertension, previous stroke, past PCI, NSTEMI, WBC, eGFR, HDL-C, LVEF, LM/three-vessel or proximal LAD involved, and antiplatelet agents during hospitalization. RCS, restricted cubic spline; HGI, haemoglobin glycation index; HR, hazard ratio; MACCEs, major adverse cardiac and cerebral events;...

Additional file 5 of A comprehensive pan-cancer analysis of necroptosis molecules in four gynecologic cancers

Jianfeng Zheng, Xintong Cai, Yu Zhang, Huihui Wang, Li Liu, Fengling Tang, Linying Liu & Yang Sun
Additional file 5: Supplementary Figure S5. The ROC curves for the risk model in the four GCs. A-C The ROC curves of CESC for training (A), validation (B), and total (C) sets. D-F The ROC curves of OV for training (D), valida©n (E), and total (F) sets. G-I The ROC curves of UCEC for training (G), validation (H), and total (I) sets. J-L The ROC curves of UCS for training (J), validation (K), and total...

Additional file 7 of A comprehensive pan-cancer analysis of necroptosis molecules in four gynecologic cancers

Jianfeng Zheng, Xintong Cai, Yu Zhang, Huihui Wang, Li Liu, Fengling Tang, Linying Liu & Yang Sun
Additional file 7: Supplementary Figure S7. Clinical value of risk score by independent prognostic analysis. A-H The Univariate Cox regression analysis and Multivariate Cox regression analysis for CESC (A-B), OV (C-D), UCEC (E-F), and UCS G-H.

Additional file 8 of A comprehensive pan-cancer analysis of necroptosis molecules in four gynecologic cancers

Jianfeng Zheng, Xintong Cai, Yu Zhang, Huihui Wang, Li Liu, Fengling Tang, Linying Liu & Yang Sun
Additional file 8: Supplementary Figure S8. The Nomogram model based on risk model and clinical features for GCs. A-B The Nomogram (A) and calibration curve (B) for CESC. C-D The Nomogram (C) and calibration curve (D) for OV. (E-F) The Nomo©m (E) and calibration curve (F) for UCEC. G-H The Nomogram (G) and calibration curve (H) for UCS.

Additional file 1 of A comprehensive pan-cancer analysis of necroptosis molecules in four gynecologic cancers

Jianfeng Zheng, Xintong Cai, Yu Zhang, Huihui Wang, Li Liu, Fengling Tang, Linying Liu & Yang Sun
Additional file 1: Supplementary Figure S1. Mutation frequency and expression variation of the 76 necroptosis-related genes (NRGs). A-D Mutation frequency of NRGs in patients with CESC (A), OV (B), UCEC (C), and UCS D. The small figure above shows the TMB, the number on the right shows the mutation frequency of each NRG, and the figure on the right shows the proportion of each vari©. E Expression levels of NRGs in four gynecological tumors. The...

Additional file 10 of Dynamic monitoring of cerebrospinal fluid circulating tumor DNA to identify unique genetic profiles of brain metastatic tumors and better predict intracranial tumor responses in non-small cell lung cancer patients with brain metastases: a prospective cohort study (GASTO 1028)

Meichen Li, Jing Chen, Baishen Zhang, Juan Yu, Na Wang, Delan Li, Yang Shao, Dongqin Zhu, Chuqiao Liang, Yutong Ma, Qiuxiang Ou, Xue Hou & Likun Chen
Additional file 10: Fig. S10 The association between extracranial and intracranial PFS with tumor/EGFR clonal status in CSF and plasma samples after 8 weeks of treatment.

Additional file 1 of CXCL1/CXCR2 is involved in white matter injury in neonatal rats via the gut–brain axis

Can Yang, Zhiyuan Feng, Hong Deng, Lu Dai, Ling He, Linlin Yin & Jing Zhao
Additional file 1: Figure S1. WB raw data of Figure 2A.

Additional file 1 of Age- and sex-specific reference values of biventricular strain and strain rate derived from a large cohort of healthy Chinese adults: a cardiovascular magnetic resonance feature tracking study

Gengxiao Li, Zhen Zhang, Yiyuan Gao, Chengcheng Zhu, Shanshan Zhou, Lizhen Cao, Zhiwei Zhao, Jun Zhao, Karen Ordovas, Mingwu Lou, Kuncheng Li & Gerald M. Pohost
Additional file 1: Fig. S1. Example of biventricular myocardial deformation analysis by Medis (Medis Medical Imaging, Leiden, the Netherlands). Contours are illustrated in LV endocardial and epicardial borders in short-axis view (a), four-chamber view (b), three-chamber view (c), and two-chamber view (d), and RV endocardial in four-chamber view (e).

Additional file 2 of Age- and sex-specific reference values of biventricular strain and strain rate derived from a large cohort of healthy Chinese adults: a cardiovascular magnetic resonance feature tracking study

Gengxiao Li, Zhen Zhang, Yiyuan Gao, Chengcheng Zhu, Shanshan Zhou, Lizhen Cao, Zhiwei Zhao, Jun Zhao, Karen Ordovas, Mingwu Lou, Kuncheng Li & Gerald M. Pohost
Additional file 2: Fig. S2. Correlation between biventricular global strain and age assessed by Medis. Linear regressions with the 95% prediction band for LV global radial strain (GRS) (a), global circumferential strain (GCS) (b), global longitudinal strain (GLS) (c), and RV free wall- global longitudinal strain (RVFW-GLS) (d).

Additional file 3 of CXCL1/CXCR2 is involved in white matter injury in neonatal rats via the gut–brain axis

Can Yang, Zhiyuan Feng, Hong Deng, Lu Dai, Ling He, Linlin Yin & Jing Zhao
Additional file 3: Figure S3. WB raw data of Figure 4A.

Additional file 6 of Effective-component compatibility of Bufei Yishen formula III ameliorated COPD by improving airway epithelial cell senescence by promoting mitophagy via the NRF2/PINK1 pathway

Min-yan Li, Yan-qin Qin, Yan-ge Tian, Kang-chen Li, Brian G. Oliver, Xue-fang Liu, Peng Zhao & Jian-sheng Li
Additional file 6.

Registration Year

  • 2022
    166

Resource Types

  • Image
    166

Affiliations

  • Henan University
    166
  • Capital Medical University
    133
  • Chinese Academy of Sciences
    128
  • Zhejiang University
    123
  • Southern Medical University
    120
  • Sun Yat-sen University
    115
  • Fudan University
    114
  • Sichuan University
    106
  • Shanghai Jiao Tong University
    103
  • Chinese Academy of Medical Sciences & Peking Union Medical College
    98