Supplementary Material 2

Supplemental material, sj-tif-6-npx-10.1177_1934578X221130874 for Cryptotanshinone From Salvia miltiorrhiza Inhibits the Growth of Tumors and Enhances the Efficacy of Chemotherapy in a Gastric Cancer Mouse Model by Wenkai Wu, Yezhi Cao, Ling Cheng, Linghu Wang, Qingsheng Yu, Hui Peng, Fuhai Zhou, Haiwei Liu and Qi Zhang in Natural Product Communications

Supplemental material, sj-tif-7-npx-10.1177_1934578X221130874 for Cryptotanshinone From Salvia miltiorrhiza Inhibits the Growth of Tumors and Enhances the Efficacy of Chemotherapy in a Gastric Cancer Mouse Model by Wenkai Wu, Yezhi Cao, Ling Cheng, Linghu Wang, Qingsheng Yu, Hui Peng, Fuhai Zhou, Haiwei Liu and Qi Zhang in Natural Product Communications

Supplemental material, sj-tif-12-npx-10.1177_1934578X221130874 for Cryptotanshinone From Salvia miltiorrhiza Inhibits the Growth of Tumors and Enhances the Efficacy of Chemotherapy in a Gastric Cancer Mouse Model by Wenkai Wu, Yezhi Cao, Ling Cheng, Linghu Wang, Qingsheng Yu, Hui Peng, Fuhai Zhou, Haiwei Liu and Qi Zhang in Natural Product Communications

Additional file 1: Fig. S1. Projection of totaL AF/AFL incidence and death and their age-standardized rates from, 1990 TO 2034.

Additional file 3: Supplementary Figure 3.

Additional file 2: Fig. S2. KEGG enrichment of differential expressed genes in septic patients compared with healthy person. a The volcano plot was constructed using the fold change values and P-adjust. Red dots indicate upregulated genes; blue dots indicate downregulated genes. b The heatmap of the differential gene expression, where different colors represent trends of gene expression in different tissues. c, d The enriched KEGG signaling pathways were selected to demonstrate the primary biological actions...

Additional file 4: Fig. S4. Effects of cilostazol treatment on complete blood counts after CLP. a, b The level of platelets (a), WBC (b), NEUT (c), MONO (d) and LYMPH (e) (n = 5). WBC, white blood cells; NEUT, neutrophil; MONO, monocyte; LYMPH, lymphocyte. The data are presented as the mean ± SEM, *P < 0.05, ***P < 0.001, and ns indicates no significant difference.

Additional file 8: Fig S7. Elimination of LSSL from serum to detect the deposition of VLRB and C1q on the surface of HeLa cells. (A) Immuno-fluorescence detection of VLRB and C1q deposited on the surface of HeLa cells treated with lamprey serum and LSSL-depleted serum. Scale bars, 10 µm. (B) A histogram shows the statistics of the above-mentioned results. The data are presented as the means ± SDs. (C) Western blotting analysis with mouse anti-VLRB...

Additional file 1: SupplementaryFigure 1. The top 10 cited countrys related to this field.

Additional file 2: SupplementaryFigure 2. The network map of top 10 institutions (A) and the top 10 cited networkmap of institutions in this field (B).

Supplemental material, sj-jpg-2-tej-10.1177_20417314221132093 for A new cell-free therapeutic strategy for liver regeneration: Human placental mesenchymal stem cell-derived extracellular vesicles by Ting Li, Yu Fu, Zeyi Guo, Honglei Zhu, Hangyu Liao, Xiaoge Niu, Lin Zhou, Shunjun Fu, Yang Li, Shao Li, Lujia Wang, Yizhou Zheng, Lei Feng, Yi Gao and Guolin He in Journal of Tissue Engineering

Supplemental material, sj-tif-5-tej-10.1177_20417314221132093 for A new cell-free therapeutic strategy for liver regeneration: Human placental mesenchymal stem cell-derived extracellular vesicles by Ting Li, Yu Fu, Zeyi Guo, Honglei Zhu, Hangyu Liao, Xiaoge Niu, Lin Zhou, Shunjun Fu, Yang Li, Shao Li, Lujia Wang, Yizhou Zheng, Lei Feng, Yi Gao and Guolin He in Journal of Tissue Engineering

Additional file 7: Figure S5. Association of each lncRNA in the identified signature with the molecular subtypes. The expression of lncRNA A NSMCE1-DT, B LINC02084, C MYOSLID, D LINC02428, and E MRPS9-AS1 in different molecular subtypes. MSI, microsatellite instability; CIN, chromosomal instability; GS, genome-stable; HM-SNV, hypermutated single nucleotide variants. -, not significant; *p < 0.05, **p < 0.01, and ***p < 0.001.

Additional file 8: Figure S6. Relationship among risk scores and clinical characteristics. Correlations of risk scores and A age, B sex, C T stage, D N stage, E metastatic status, F total stage, G immune score, and H Clusters. ns, not significant; *p < 0.05, **p < 0.01, and ***p < 0.001.

Additional file 3: Figure S2. Consensus clustering based on prognostic lipid metabolism-related lncRNAs. A Consensus clustering cumulative distribution function (CDF) for k = 2 to 9. B Relative changes in the areas under the CDF curve for k = 2 to 9. Consensus matrix similarity for C 2, D 3, E 4, and F 5 clusters.

Additional file 4: Figure S3. Association of immune checkpoints with Clusters and prognostic risk groups. The expression of immune checkpoints A PD-1, B PD-L1, C CTLA-4, D IDO1, E IDO2, F HAVCR2, and G LAG3 in Clusters 1 and 2. The expressions of H PD-L1, I PD-1, J CTLA-4, K IDO1, L IDO2, M HAVCR2, and N LAG3 in different risk groups. PD-1, programmed cell death 1; PD-L1, programmed cell death ligand 1; CTLA-4, cytotoxic...

Additional file 6: Figure S4. Association of each lncRNA in the identified signature with the immune subtypes. The expression of lncRNA A NSMCE1-DT, B LINC02084, C MYOSLID, D LINC02428, and E MRPS9-AS1 in different immune subtypes. -, not significant, *p < 0.05, and ***p < 0.001.

Additional file 1: Supplementary Figure 1. MMP-13 levels in the medium of IL-1β-induced C28/I2 cells detected by ELISA.

Additional file 1: Supplementary Figure S1. Mutation frequency and expression variation of the 76 necroptosis-related genes (NRGs). A-D Mutation frequency of NRGs in patients with CESC (A), OV (B), UCEC (C), and UCS D. The small figure above shows the TMB, the number on the right shows the mutation frequency of each NRG, and the figure on the right shows the proportion of each vari©. E Expression levels of NRGs in four gynecological tumors. The...

Additional file 5: Supplementary Figure 5.

Additional file 7: Fig. S7. Effect of LPS and CD40L on TRAFs proteins in EGCs. a Representative western blot images of TRAFs proteins expression in EGCs. b-g Western blot analysis of TRAF1 (b), TRAF2 (c), TRAF3 (d), TRAF4 (e), TRAF5 (f) and TRAF6 (g) expression in different groups of EGCs (n = 6). The data are presented as the mean ± SEM, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.

Additional file 1: Figure S1. The AR−/− mice genotyping and the expression level of AR in AR−/− mice. (A) AR null allele were identified by northern blot analysis. The expected bands of ∼119 bp is observed in the wild-type mice while not seen in AR−/− mice. (B) Western blot analyze the AR expression in the AR−/− mice. (C) Immunofluorescence analyze the AR expression in the spinal cord of AR−/− mice at 3 day following BPRA...

Additional file 6: Figure S6. Forest plot for withdrawals due to adverse events in ADA and control groups

Supplemental material, sj-tif-1-tct-10.1177_15330338221123634 for Ixazomib Combined With Autologous Stem Cell Transplantation for POEMS Syndrome: A Case Report and Meta-Analysis by Ji Ma, Xiaoyue Wang, Hui Lu, Zhihao Liang and Liang Wang in Technology in Cancer Research & Treatment