Chronic kidney disease (CKD) in clinical is defined as a gradual loss of kidney function for more than 3 months. The pathologic course of CKD is characterized by extensive renal fibrosis; thus, preventing renal fibrosis is vital for the treatment of CKD. It has been reported that microRNA (miR)-374a-5p was under-expressed in renal venous blood samples from patients with CKD. In addition, it exhibited anti-apoptotic effects in renal tissues suggesting that miR-374a-5p may play an...

The dysregulated circular RNAs (circRNAs) are linked to progression and chemoresistance in colorectal cancer (CRC). However, the role of circRNA protein tyrosine kinase 2 (circPTK2) in CRC progression and chemoresistance is uncertain. The circPTK2, microRNA (miR)-136-5p, m6A ‘reader’ protein YTH domain family protein 1 (YTHDF1), β-catenin and cyclin D1 abundances were examined via quantitative reverse transcription PCR or Western blotting. The progression was investigated by cell counting kit-8 (CCK-8), colony formation, transwell and xenograft analysis....

Additional file 1: Supplementary Figure S1. BUSCO assembly evaluation results. C (complete): matches the BUSCO database sequence; F (fragmented): only part of the sequence can be compared with the BUSCO database; D (duplicate): multiple genes are compared with the same BUSCO; M (missing): the filtered sequence.

Additional file 1: Supplementary Figure 1.

Additional file 2: Supplementary Figure 2.

Additional file 3: Supplementary Figure 3.

Additional file 3: Figure S1. (A, D, G) The heat map of 10 prognostic DEOSG expressions in the train (A), testing (D), and entire sets (G), respectively. (B, E, H) The comparison of 10 prognostic DEOSG expressions between high- and low-risk groups in the training (B), testing (E), and entire sets (H), respectively. (C, F, I) The correlations among 10 prognostic DEOSG between high- and low-risk groups in the training (C), testing (F), and entire...

Additional file 4: Figure S4. (A) KEGG pathways involved by YAP expression related genes.

Additional file 4: Figure S4. (A) KEGG pathways involved by YAP expression related genes.

Additional file 2: Figure S2. (A) Quantifications of Colony formation assays. (B) Flow cytometry analysis was utilized in the control or WZ35-treated HCCLM3 cells to measure the possible arrest in the cell cycle. Representative fitting curve of the cell cycle qualitatively illustrated the percentage of cells in G1, S and G2/M phase. (C) Apoptosis was assessed via flow cytometry in HCCLM3 cells with or without the treatment of WZ35 (10 μg/mL) for 18h using Annexin...

Additional file 6: Figure S6. (A) Heatmap visualizing DEGs' in liver cancer samples from TCGA datasets. (B) Heatmap visualizing glucose metabolism genes' expression levels exposed to different YAP1 expression in liver cancer samples from TCGA datasets.

Additional file 7: Figure S7. (A) Volcano plot of RNA-seq data from GEO database with SLC2A1 being marked out. (B) Box plot exhibits the distinct expression of SLC2A1 in the normal and the tumor samples, with the blue box being the representative of the tumor samples and the red box of the normal samples. (C) Kaplan–Meier analysis displaying survival for liver cancer patients stratified by expression levels of SLC2A1 (P = 3.7×10-6). (D) Western blotting...

Additional file 9: Figure S9. (A and C) Time-dependent ROC curves analyzing the potential value of expression levels of SLC2A1 (A) and combination of SLC2A1 and YAP1 (C) in diagnosis of liver cancer. (B and D) Kaplan–Meier analysis displaying survival rate for liver cancer samples from GEO datasets according to the expression levels of single factor of SLC2A1 (B) (P = 0.00035) and multi factors of YAP1 and SLC2A1 (D) (P < 0.0001). High integrated...

Supplemental material, sj-png-1-taj-10.1177_20406223221143245 for Chest X-ray features facilitate screening for pulmonary hypertension caused by fibrosing mediastinitis by Mingfang Zhou, Bo Li, Yaling Chen, Aqian Wang, Yining Zhu, Yu Li, Hongling Su, Jingchun Fan, Yan Zhang and Yunshan Cao in Therapeutic Advances in Chronic Disease

Additional file 6: Figure S2. (A, F, K) Comparison of the relationship between the clinical characteristics of patients between high- and low-risk groups in the training, testing, and entire sets, respectively. (B–E) The scatter diagram showed the relationship between gender (B), clinical stage (C), T stage (D), N stage (E) and the risk score in the training set. (G–J) The scatter diagram showed the relationship between gender (G), clinical stage (E), T stage (F), N...

Supplemental material, sj-tif-2-cll-10.1177_09636897221139103 for Low-Dose Anti-Thymocyte Globulin Plus Low-Dose Posttransplant Cyclophosphamide as an Effective Regimen for Prophylaxis of Graft Versus Host Disease After Haploidentical Peripheral Blood Stem Cell Transplantation With Maternal/Collateral Related Donors by Ting Li, Qiaomei He, Jun Yang, Yu Cai, Chongmei Huang, Xiaowei Xu, Huiying Qiu, Jiahua Niu, Kun Zhou, Yin Zhang, Xinxin Xia, Yu Wei, Chang Shen, Xueying Ding, Yin Tong, Liping Wan and Xianmin Song in Cell Transplantation

BETA PRIME: Phase I study of AdAPT-001 as monotherapy and combined with a checkpoint inhibitor in superficially accessible, treatment-refractory solid tumors Infographic

Supplemental material, sj-png-2-taj-10.1177_20406223221143245 for Chest X-ray features facilitate screening for pulmonary hypertension caused by fibrosing mediastinitis by Mingfang Zhou, Bo Li, Yaling Chen, Aqian Wang, Yining Zhu, Yu Li, Hongling Su, Jingchun Fan, Yan Zhang and Yunshan Cao in Therapeutic Advances in Chronic Disease

Supplementary materials to the article ' National survey on unplanned readmissions for diabetic kidney disease: Insight from a new paradigm of obesity '

MRI images of colon

Supplementary materials to the article ' National survey on unplanned readmissions for diabetic kidney disease: Insight from a new paradigm of obesity '

Additional file 5: Figure S5. Genes in central carbon metabolism pathway of YAP high expression group on KEGG graph rendered by pathview. Gene expression levels are indicated as significantly higher (red), unchanged (gray), or lower (green).

Supplemental material, sj-tif-3-onc-10.1177_11795549221134735 for First-Line Osimertinib in Patients With EGFR-Mutated Non-Small Cell Lung Cancer: Effectiveness, Resistance Mechanisms, and Prognosis of Different Subsequent Treatments by Naifu Nie, Jianghua Li, Jian Zhang, Jie Dai, Zhulin Liu, Zhenyu Ding, Yubo Wang, Mengxiao Zhu, Chen Hu, Rui Han, Huan Tang, Li Li and Yong He in Clinical Medicine Insights: Oncology

Supplementary materials to the article ' National survey on unplanned readmissions for diabetic kidney disease: Insight from a new paradigm of obesity'

Additional file 3: Supplementary Figure 3.