4 Works

Neferine hinders choriocarcinoma cell proliferation, migration and invasion through repression of long noncoding RNA-CHRF

Gang Wang, Ping Wang, Xiaojun Yan & Jing Liu
The comprehensive pathological peculiarities of Neferine (NEF) have been testified in disparate diseases. But, the functions of NEF in choriocarcinoma progression remain unexplored. The research endeavoured to uncover the anti-tumour action of NEF in choriocarcinoma cells. NEF at diverse doses was employed to dispose JEG-3 and HTR-8 cells, and cell viability assessment adopted CCK-8 assay. After 60 μg/mL NEF management, BrdU-positive cells, apoptosis, migration, invasion and correlative factors were assessed. CHRF expression in choriocarcinoma tumour...

Identification of hepatocellular carcinoma-related genes associated with macrophage differentiation based on bioinformatics analyses

Jun Cao, Chi Zhang, Guo-Qing Jiang, Sheng-Jie Jin, Qian Wang, Ao-Qing Wang & Dou-Sheng Bai
Macrophage differentiation is associated with tumorigenesis, including the tumorigenesis of hepatocellular carcinoma (HCC). Herein, we explored the value of macrophage differentiation-associated genes (MDGs) in the prognosis of HCC using data from The Cancer Genome Atlas (TCGA) and the International Cancer Genome Consortium (ICGC) databases. We performed multivariate Cox regression analyses to identify the hub genes affecting HCC patient prognoses. The correlations between hub genes and macrophage differentiation and immune checkpoint inhibitors (PD-1, PD-L1, and CTLA4)...

Homologous chromosomes undergo sequential quasi-stable interactions during meiotic prophase

Trent Newman
The pairing of homologous chromosomes in meiosis I is essential for sexual reproduction and is mediated, in part, by the formation and repair of Spo11-induced DNA double strand breaks (DSBs). In budding yeast, each cell receives 150-200 DSBs, yet only a fraction go on to form crossover products. How and why the cell initially coordinates so many interactions along each chromosome is not well understood. Using a fluorescent reporter-operator system (FROS), we measure the kinetics...

RETRACTED ARTICLE: Neferine hinders choriocarcinoma cell proliferation, migration and invasion through repression of long noncoding RNA-CHRF

Gang Wang, Ping Wang, Xiaojun Yan & Jing Liu
We, the Editors and Publisher of the journal Artificial Cells, Nanomedicine, and Biotechnology, have retracted the following article: Gang Wang, Ping Wang, Xiaojun Yan & Jing Liu (2019) Neferine hinders choriocarcinoma cell proliferation, migration and invasion through repression of long noncoding RNA-CHRF, Artificial Cells, Nanomedicine, and Biotechnology, 47:1, 4089–4096, DOI: 10.1080/21691401.2019.1671429 Since publication, concerns have been raised about the integrity of the data in the article. When approached for an explanation, the authors have been...

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  • Stanford University
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  • Sun Yat-sen University
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  • Zhejiang University
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  • Huazhong University of Science and Technology
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  • Guangzhou Medical University
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  • Fudan University
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  • Tianjin Medical University Cancer Institute and Hospital
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  • Second Hospital of Hebei Medical University
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  • Affiliated Hospital of Southwest Medical University
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  • Jiangsu Academy of Agricultural Sciences
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